Number and location of draining veins in pediatric arteriovenous malformations: association with hemorrhage

2014 ◽  
Vol 14 (5) ◽  
pp. 538-545 ◽  
Author(s):  
Christopher P. Kellner ◽  
Michael M. McDowell ◽  
Michelle Q. Phan ◽  
E. Sander Connolly ◽  
Sean D. Lavine ◽  
...  

Object The significance of draining vein anatomy is poorly defined in pediatric arteriovenous malformations (AVMs). In adult cohorts, the presence of fewer veins has been shown to lead to an increased rate of hemorrhage, but this phenomenon has not yet been studied in pediatric AVMs. This report analyzes the impact of draining vein anatomy on presentation and outcome in a large series of pediatric AVMs. Methods Eighty-five pediatric patients with AVMs were treated at the Columbia University Medical Center between 1991 and 2012. Charts were retrospectively reviewed for patient characteristics, clinical course, neurological outcome, and AVM angioarchitectural features identified on the angiogram performed at presentation. Univariate analyses were performed using chi-square test and ANOVA when appropriate; multivariate analysis was performed using logistic regression. Results Four patients were excluded due to incomplete records. Twenty-seven patients had 2 or 3 draining veins; 12 (44.4%) of these patients suffered from hemorrhage prior to surgery. Fifty-four patients had 1 draining vein; 39 (72.2%) of these 54 suffered from hemorrhage. Independent predictors of hemorrhage included the presence of a single draining vein (p = 0.04) and deep venous drainage (p = 0.02). Good outcome (modified Rankin Scale [mRS] score < 3) on discharge was found to be associated with higher admission Glasgow Coma Scale (GCS) scores (p = 0.0001, OR 0.638, 95% CI 0.40–0.93). Poor outcome (mRS score > 2) on discharge was found to be associated with deep venous drainage (p = 0.04, OR 4.68, 95% CI 1.1–19.98). A higher admission GCS score was associated with a lower discharge mRS score (p = 0.0003, OR 0.6, 95% CI 0.46–0.79), and the presence of a single draining vein was associated with a lower mRS score on long-term follow-up (p = 0.04, OR 0.18, 95% CI 0.032–0.99). Conclusions The authors' data suggest that the presence of a single draining vein or deep venous drainage plays a role in hemorrhage risk and ultimate outcome in pediatric AVMs. Small AVMs with a single or deep draining vein may have the highest risk of hemorrhage.

2020 ◽  
Vol 44 (3) ◽  
pp. 135-141
Author(s):  
Evan Cyrkin ◽  
Aaron Myers ◽  
Jaffer Shariff ◽  
Richard Yoon

Purpose: To evaluate utilization and trends associated with patients who presented with emergencies at a community dental clinic at Columbia University Medical Center, New York, NY. Study design: Data from deidentified dental records of patients aged 0–12 years old who presented as emergencies for oral and dental reasons for 2012, 2013, and 2014 were collected. Variables analyzed included demographic information, oral diagnosis, and current health status. Frequency distributions analysis, chi-square test and analysis of variance (ANOVA) test were performed using Stata 13.0. Results: There were 4,328 dental and oral-related emergencies with a mean age of 6-years-old. Approximately 50% were females, 71% were Hispanic, and 90% had Medicaid managed care. Most emergencies (49%) were caries-related, 41% were considered atraumatic in nature, and approximately 10% were traumatic. About 10% of patients presented with comorbidities and 37% were either first-time patients or patients that presented exclusively for emergencies. Acute tooth pain (45%) caused by dental caries was the most common chief complaint. The trends for emergency presentations showed a significant decrease (p&lt;.001) between years 2012–2014 for caries-related visits and a significant increase (p&lt;.001) between 2012–2013 and 2012–2014 for atraumatic visits. Conclusions: Caries-related dental diagnoses were more common than trauma-related diagnoses. The most common caries-related diagnosis was pulp necrosis for both primary and permanent dentitions while the most common traumarelated diagnosis was subluxation for the primary dentition and enamel-dentin fracture for the permanent dentition.


2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 377-377
Author(s):  
Caitlin Takahashi ◽  
Ravi Shridhar ◽  
Jamie Huston ◽  
Anjan Jayantilal Patel ◽  
Richard H. Brown ◽  
...  

377 Background: Extra-hepatic cholangiocarcinomas (EHC) are low-incidence cancers that are difficult to diagnose and associated with a dismal prognosis. Surgery remains the only option for durable survival however R1 resections are high. We sought to examine the impact of adjuvant therapies on survival in patients with EHC. Methods: Utilizing the National Cancer Database we identified patients who underwent resection for EHC. We then stratified by adjuvant therapy (chemo(AC) or chemoradiation(CRT). Baseline comparisons of patient characteristics were made using Mann-Whitney U, Kruskal Wallis and Pearson’s Chi-square test as appropriate. Survival analyses were performed using the Kaplan-Meier method. Multivariable cox proportional models (MVA) were developed to identify predictors of survival. All statistical tests were two-sided and α < 0.05 was considered significant. Results: We identified 4334 patients who underwent EHC resection: AC = 775, CRT = 1254, no adjuvant (NA) therapy = 2305 and a median age of 67 (18-90) years. R0 resections was performed in 71.6% of patients and the median LN harvest was 9 (3-18). R0 resections and lymph node negative patients demonstrate improved survival p < 0.001 and p < 0.001. Adjuvant therapy did not improve survival in R0 resections, p = 0.2. However survival was benefited in R1 patients, with those receiving CRT demonstrating the most significant improvement: median and overall 5-year survival AC = 16.7 months 8%, CRT = 23.1 months, 20.4%, and NA = 16.1 months and 11.6% p < 0.001. In LN- patients CRT (47.3 months, 47%) but not AC (45 months, 44.5%) demonstrated benefit in survival compared to NA (37.8 months, 40.1) p = 0.04 and p = 0.7. Additionally, patients with LN+ and R1 resection had survival benefit when treated with (CRT 24.9 months and 24.3%), compared to NA (20.2 and 21.1%), p = 0.02. AC (24 months and 24%) did not demonstrate survival in these patients, p = 0.21. MVA demonstrated that age, T-stage, LN+, R0 resection and CRT were predictors of survival. Conclusions: Adjuvant CRT improves survival for patients with EHC who underwent R1 resections, and in LN- and LN+ patients. However, AC only benefited node positive patients with R0 resections. Patients with resected EHC should be referred for adjuvant CRT.


2021 ◽  
pp. 112067212110280
Author(s):  
Maria L Salvetat ◽  
Carlo Salati ◽  
Patrizia Busatto ◽  
Marco Zeppieri

Purpose: To assess ocular pathologies admitted to Italian Emergency Eye Departments (EEDs) during the COVID-19 pandemic national lockdown in 2020 in comparison with the same period in 2019. Methods: Electronic records of all patients presenting at EEDs of two tertiary-care Eye Centers during the COVID-19 national lockdown in Italy (March 10–May 3, 2020) were compared with the equivalent period in 2019. Main outcomes were patient age, gender, and diagnoses. Statistical analysis included unpaired Student t-tests, Poisson regression, and chi-square test. Results: Overall EED visits significantly decreased by 54.1% during the 2020 lockdown compared to 2019 (851 vs 1854, p < 0.001). During lockdown, patients showed comparable mean age (52.8 years in 2020 vs 53.3 years in 2019, p = 0.52) and significant male gender bias (61.1% in 2020 vs 55.8% in 2019, p < 0.0001). The most frequent pathologies were eye inflammations, trauma-related incidents, and spontaneous acute vitreous detachment. Patients with inflammation, headache/hemicrania, and spontaneous subconjunctival hemorrhages were significantly less, whereas those with trauma-related diagnoses were significantly higher during the lockdown as compared with 2019 ( p < 0.05). The proportion of non-urgent visits decreased from 17% in 2019 to 8% in 2020 ( p < 0.001). Conclusions: During the 2020 lockdown, there was a significant reduction of accesses to EED, especially for non-urgent pathologies. Potentially visual function threatening conditions, such as trauma-related pathologies, retinal detachment or ruptures, and wet AMD, showed lower number of cases but higher or stable proportion relative to the total caseload, suggesting a correct and efficient access to ophthalmic health care during the pandemic period.


2018 ◽  
Vol 4 (4) ◽  
pp. 295-300 ◽  
Author(s):  
F.O. Miantsia ◽  
F. Meutchieye ◽  
S. Niassy

The current work is aimed at generating information on giant crickets and the impact of commonly used pesticides on the natural population of these crickets. Data was collected based on interviews and complemented with field observations. Out of 319 respondents surveyed, 290 were aware of the use of the giant cricket as a food source, and 161 were active consumers. Regarding the availability of the giant cricket, respondents reported that the crickets’ populations were diminishing because of farming practices. About 219 persons reported that commonly used herbicides harm giant crickets at different stages. This could be attributed to the scarcity of this species, as mentioned by 233 respondents. The results showed that 130 respondents were engaged in gathering giant crickets for consumption. This insect gathering is related to soil tilling. Chi-square test showed a significant dependence relationship between herbicides use and cricket scarcity. Although less than a majority (129) of respondents are making regular use of persistent pesticides (herbicides), it has been observed that intensive use of pesticides could become a popular practice in smallholder farming categories. This paper thus suggests the need for training and surveillance concerning the trade of pesticides in the region and proposes further investigations into pesticides residues or traces in collected giant crickets consumed in the study site and in all areas with similar conditions.


Author(s):  
Ch.Narahari Et. al.

In the present study we analyze the employees’ perception towards coping measures adopted byfirms in software industry. The considered coping constructs adopted for the study in stress abatement areVenting of Emotions,Problem Focused, Seeking Information and emotional support, Positive Emotion-Focused, were, employee perception was acquired by a systematic survey.A total sample of 800 employees’perceptions have been collected through simple random technique and out of which survey respondents, irregular responses are eliminated finally 756 samples are determined for statistical analysis. Chi-square test was performed to determine the association between perceptions and model constructs. Results are reported and discussions are made as per the results and in correlation between results of previous literature.Finally, suggestions and future indication for extension of the study are proposed.


2019 ◽  
Vol IV (I) ◽  
pp. 95-107
Author(s):  
Sajjad Ali ◽  
Muhammad Saqib Ilmas ◽  
Shajee Hassan

This study analyzes the impact of watching television sports channels on the promotion of sports activities among the students of the University of Sargodha. The aim of the study is to explore the impact of sports channels on students. Previous researches are used to set up the concepts of the present study. In this research, a survey technique is used to collect the data. The population of the study consists of male and female students of the University of Sargodha. In this research, the Stratified and Purposive sampling technique is used, through which specification characteristics of the respondent's demographics. The study explores the impact of sports channels in the view of Uses and Gratification Theory. The data for this study is collected through the use of a well-designed questionnaire. Chi-square test and other statistical tests like ANOVA and t-Test are applied to test the hypothesis. The finding shows that more the exposure to TV sports channels more the information level of students of the University of Sargodha.


2021 ◽  
Vol 9 (2) ◽  
pp. 53-63
Author(s):  
Dragana Pešić-Jenačković

Motivation and employee satisfaction are very important precondition for the effectiveness of work and the achievement of set goals for individuals and organizations. Consequently, continuous measurement of employee motivation and satisfaction is essential to improve company's efficiency and improve human resource use. The results of a well-planned, detailed and adequate methods and techniques of research on employee motivation and satisfaction can be applied to the design of various schemes in order to reduce absenteeism and employee turnover and overall business success. In this paper, the emphasis is on the methodology of researching employee motivation and satisfaction. In addition to the elaboration of questionnaires with scales for measuring the motivation and satisfaction of employees, it is explained in which situations, in which types of questions and answers, respectively, types of data, and how certain statistical techniques are applied, such as: T-test, One-factor analysis of variance (ANOVA), Chi-square test, Point-two-series correlations. Also, the importance of using the subsequent post hoc test (LSD comparison) in the analysis of variance, as well as the indicators of correlation, the strength of the impact, such as: phi correlation coefficient, Kramer's coefficient and contingency coefficient, is pointed out in the Chi-square test. In addition to the mentioned techniques and indicators from SPSS, the role of certain indicators (eta squared and coefficient of determination) is calculated, which are calculated using data from research results and with the help of certain formulas


2018 ◽  
Vol 5 (1) ◽  
pp. 16-22
Author(s):  
Jaenudin ◽  
Sandi Aprianto ◽  
Citra Setyo Dwi Andini

Background: Garbage is something material or solid objects that is no used by humans. The impact or risk of improper handling of garbage can cause to environmental damages that can cause health problems and disesase, one of them is diarrhea disease. According to the health profile of West Java Province (2012) showed that the 1.906.886 diarrhea incidence. Cirebon City is ranked ninth with 88,702 diarrhea incidence. Purpose: The purpose of this research is to know the relationship of waste management with the incidence of diarrhea In Argasunya Village Cirebon City. Method: This research used descriptive correlation with kohort retrospekif approach. The population in this study that is all the people who suffer from diarrhea in the Argasunya Village with 72 respondents. The sample in this study using total sampling with 72 respondents who suffer from diarrhea. The research instrument used the observation sheet of waste management and the result of the status of the patient according the medical record data in Sitopeng Public Health Center. The analysis used univariate and bivariate used Chi Square test. Result: The result of univariate analysis showed that most of the waste management did not fulfill the requirement of 59 respondents (81,9%) and most of the acute diarrhea was 62 respondents (86,1%). There was no significant relationship of waste management with the incidence of diarrhea In Argasunya Village Cirebon City, p-value = 0,677.


Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Leslie Corless ◽  
Tamela L Stuchiner ◽  
Cameron Garvin ◽  
Alexandra C Lesko ◽  
Elizabeth Baraban

Background: Few studies have shown the impact of substance use (SU) on treatment and outcomes of stroke patients. Research suggests stigma related to SU impacts patient experience in healthcare settings. In this study we assessed whether there were differences in patient characteristics and outcomes for stroke patients with SU compared to those with no substance use (NSU). Methods: Retrospective data from two Oregon hospitals included patients admitted with stroke diagnosis, 18 years or older, who discharged between October 2017 and May 2019. Patients with documented SU and specific SU type were compared to patients with NSU with regard to demographics, medical history, stroke subtypes, treatment, discharge disposition and length of stay (LOS). SU was defined as any documented abuse of alcohol (ETOH), methamphetamine (MA), cannabis, opiates, cocaine, benzodiazepines, and Methyl-enedioxy-methamphetamine (MDMA). Non parametric median tests and Pearson’s chi square tests were used. Results: Among 2,030 patients included in the analysis, 13.8% (n=280) were SU and 86.2% (n=1,750) were NSU. Patients with SU were significantly younger, median age (61 vs. 73, p <.001) and less were female (35.4% vs. 53.6%, p <0.001). Those with SU had lower prevalence of dyslipidemia (43.6% vs. 59.5%, p <0.001), AFIB (12.5% vs. 22.2%, p <0.001), and previous TIA (6.1% vs 10.8%, p=0.02), and more smoked (54.3% vs 13.3% p <0.001). More patients with SU arrived via transfer (38.4% vs 27.4%, p=.001). Fewer patients with SU expired or were discharged to hospice (8.9% vs 13.7%) and a greater percent left against medical advice (AMA) (3.2% vs 0.6%) (p<.001). When comparing specific SU types to NSU, all SU groups were younger, had similar medical histories and a greater proportion left AMA. Only MA users had differentiating stroke diagnoses with a higher percent of SAH (14.5% vs 5.6%) (p=.003) in addition to longer LOS (6 vs 4 days, p=.006). No differences were found in acute stroke treatment rates. Conclusion: Patients with SU were demographically different from the NSU population and did differentiate on some stroke care outcomes and processes, potentially indicating opportunities to address stigma around substance use to meet the needs of patients with both stroke and substance use.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 318-318
Author(s):  
Cierra N Crowell ◽  
Erin B Perry

Abstract Work in other species has demonstrated an impact of gestational exposure on flavor preferences. Although equine palatability preferences in mature horses have been identified, feeding behaviors in growing horses are not well documented. The objective of this study was to evaluate the impact of exposure to common palatants in utero on feeding preferences of weanlings. Stock-type weanlings (n = 4) weighing 225(±18.15) kg at 29(±2.55) weeks of age were used in a side-by-side comparison test with a divided feeding platform. Common palatants (apple and anise) were utilized throughout the broodmare gestational period. A novel palatant, peppermint, was withheld during gestation to identify impacts associated with neophobic tendencies. Treatments were offered once daily for three consecutive days across three periods (4 weeks apart) using a pelleted concentrate feed with an application rate of 0.375 mL/0.23 kg. Weanlings were allowed free access to the feeding platform with identical pans spaced 6” apart for 20 minutes. Treatment location within the feeding platform was changed daily to limit effects associated with side-eating. Data were measured as a Chi Square test of SAS using PROC FREQ statement with α ≤. 0.05. Despite gestational exposure to apple and anise, no preference was measured in palatability assessments including First Sniff (P = 0.29), First Consumed (P = 0.70), First Finished (P = 0.29). These data suggest that exposure in utero failed to elicit a preference for common palatants in weanling horses. Additionally, these data fail to demonstrate a neophobic effect for a novel palatant, peppermint.


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