scholarly journals DIAGNOSTIC EFFICIENCY OF LIQUID BASED CYTOLOGY COMPARED WITH CONVENTIONAL PAP.

Author(s):  
Pammy Pravina ◽  
Rita Sinha

Aim: Diagnostic efficiency of liquid based cytology compared with conventional pap Methods: The present analytical study entitled was conducted in the Department of Obstetrics and Gynecology, Nalanda Medical College and Hospital, Patna, Bihar, India over the period of 1 year. The study includes total 100 subjects. Results: Mean age of the study population was 39.12 years. Majority belongs to 30-40 years of age group. Vaginal discharge was the major problem reported by the study subjects. There were statistically significant differences of satisfactory/unsatisfactory rate and Diagnostic efficacy i.e. sensitivity and specificity of LBC is greater than CPS for evaluation of cervical cytology. Conclusions: the present study concluded that LBC may improve the sample's quality, reduce the number of unsatisfactory smear and increases the diagnostic efficacy in comparison to CPS. Keywords: Cervical cancer, Conventional pap smear, Liquid-based cytology, Sensitivity, Specificity.

Author(s):  
Shruti Singh ◽  
Amit Gupta ◽  
D. Nath ◽  
Hema J. Shobha

Background: Cervical cancer is the second highest cause of cancer-related mortality in women, and the only sign of this cancer in the early stages is the loss of abnormal cells. Clinical signs of the disease appear only after cancer has reached advanced stages. Conversely, this cancer in precancerous conditions is completely curable and screening with conventional Papanicolaou (CP) has reduced the mortality by 70% but it is also associated with a significant number of false-negative cases (20-50%). In 1996, liquid-based cytology (LBC) method was developed to overcome the disadvantages of the previous method expecting to have good features such as high sensitivity, faster sample preparation, and decreased the rate of inadequate smears.Methods: This descriptive-analytic study was conducted at the Department of Pathology and Department of Obstetrics and Gynaecology, government medical college, Datia for the period of 11 months from April 2018 to February 2019. The study includes total 80 subjects. Total No. of Pap smear examined (both LBC and CPS) are 160.Results: There were statistically significant differences of satisfactory/unsatisfactory rate, smear cellularity, background clarity and detection of endocervical cells, in between liquid based cytology and conventional Pap smear finding (p<0.05). Diagnostic efficacy i.e. sensitivity and specificity of LBC is greater than CPS for evaluation of cervical cytology.Conclusions: Results shows, that LBC may improve the sample's quality, reduce the number of unsatisfactory smear and increases the diagnostic efficacy.


2021 ◽  
Vol 15 (6) ◽  
pp. 1249-1252
Author(s):  
R. Mukhtar ◽  
A. U.- Rehman ◽  
A. Ilyas ◽  
M. J. Khan ◽  
R. Liaqat ◽  
...  

Aim: To determine the frequency of Bacterial vaginosis by pap smear cytology and find its association with its sociodemographic determinants. Study design: Cross sectional analytical study Place and duration of study: Department of Histopathology, Shaikh Zayed Hospital, Lahore from 1st January 2016 to 31st October 2016. Methodology: Two hundred and sixty pap smears of married women of reproductive age group with vaginal discharge who attended Gynecology OPD were included. Proper history regarding age, socioeconomic status, age of marriage, literacy level, smoking, and nutritional status was taken. Results: Disease prevalence was found to be 19.2%(50)in this sample of 260 while 9.1% had Candidiasis, 47%, 17.2% ,3.7%, 4.1% had Mild nonspecific inflammation, Moderate nonspecific inflammation, Moderate to severe nonspecific inflammation, and negative smears respectively. Bacterial vaginosis was associated with age, monthly income, illiteracy, early age at marriage, history of abortion and nutritional status with significant p-value ≤ 0.05. However no association was found between the disease and marital status, smoking and pallor. Conclusion: Low socioeconomic status, literacy, age >35, nutritional status is strongly related to occurrence of bacterial vaginosis in women of reproductive age group with vaginal discharge. Key Words: Bacterial vaginosis, Pap smear, Sociodemographic determinants


Author(s):  
N. Swathi ◽  
Voleti Vijaya Kumar ◽  
M. Farjana ◽  
M. Vishnu Vardhan ◽  
M. Munendra ◽  
...  

Objective: To determine the prevalence of hypothyroidism in a rural population of Nandyal.Methods: A prospective study was conducted in Santhiram medical college and general hospital, Nandyal from July 2017 to December 2017, to study the prevalence of hypothyroidism among the population. Results: In this study, 1000 patients were evaluated for the thyroid functioning, among them n=104(10.4%) showing positive results in hypothyroidism. The positive 104 patients showed that n=63 (60.57%) of the population are in the age limit of 21-40. Out of the same population are n=11 (10.6%) are male and female are n=93 (89.43%). In age group distribution more prevalence was observed in 21-30 y of age group n=36 (34.61%). In this study, sub-clinical hypothyroidism was prevalent in females n=80 (76.92%) than males n=10 (9.61%).Conclusion: Our study demonstrates that hypothyroidism was higher in a female with age group as 21-40 y and there is a significant prevalence of hypothyroidism in the study population.


2018 ◽  
Vol 16 (1) ◽  
pp. 3-7
Author(s):  
Rumi Farhad Ara ◽  
Jahangir Alam

Background: Teenage pregnancy is a huge problem in developed as well as developing countries.Objective: The purpose of the present study was to see the socio-demographic characteristics of teenage pregnant mother.Methodology: This cross-sectional study was conducted in the Department of Obstetrics and Gynecology, Dhaka Medical College & Hospital, Dhaka, Bangladesh and Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh from April to July 1999 for a period of four (4) months. The teenager mothers with the age group of 11 to 19 years who were admitted in the study period was selected as study population. At the time of entry, all relevant parameters like religion, residence, occupation, education and monthly income were recorded in a predesigned data sheet.Result: A total number of 50 teenager mothers were recruited for this study. Majority of the study population were Muslim which was 45(90.0%) cases followed by Hindu which was 3(6.0%) cases. Maximum were non-city dweller which was 26(52.0%) cases followed by city and slum dwellers which were 16(32.0%) cases and 8(16.0%) cases respectively. Majority of the study were housewife which was 49(98.0%) cases. Monthly income was less than 3000 taka in 29(58.0%) cases. Majority of the study population were completed the primary education level which was 26(52.0%) cases. Married was found in 49(98.0%) cases.Conclusion: In conclusion Muslim non-city dwellers housewife were the most common group of teenager motherJournal of Science Foundation 2018;16(1):3-7


1970 ◽  
Vol 4 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Md Din-ul Islam ◽  
Sufi HZ Rahman ◽  
SM Shamsuzzaman ◽  
Naima Muazzaman ◽  
Nasim Ahmed ◽  
...  

The present study was conducted in the department of Microbiology, Dhaka Medical College, Dhaka during the period of January, 2007 to December, 2007. Urine samples were collected from 86 dyspeptic patients undergoing upper Gastrointestinal Tract (GIT) endoscopy to determine anti-H. pylori IgG antibody by an ELISA method. Gastric biopsy tissues were tested for culture, rapid urease test and H&E/Giemsa stain. Out of 86 endoscopic biopsy specimens, 45 (52.33%) were culture positive, 63 (73.26%) were rapid urease test positive and 64 (74.42%) were H&E/Giemsa stained positive for H. pylori. According to operational standard definition, among the 86 study population, 66 (76.74%) were H. pylori infected, 16 (18.60%) were uninfected and 4 (4.65%) were indeterminate. Among 66 H. pylori infected cases, 63 (95.45%) were urine ELISA positive and among 16 uninfected cases 3 (18.75%) were urine ELISA positive. Out of 86 study population, 66 (76.74%) were urine ELISA positive. The sensitivity, specificity, PPV, NPP and accuracy of urine ELISA were 95.45%, 81.25%, 95.45%, 81.25% and 92.68% respectively. The result of the study shows that H. pylori infection can be rapidly and reliably diagnosed by detecting anti-H. pylori IgG from urine. Key words: H. pylori; ELISA; GIT; IgG. DOI: http://dx.doi.org/10.3329/bjmm.v4i1.8463 BJMM 2011; 4(1): 14-17


Author(s):  
Prakash Kumar Nayak ◽  
Sudeep Satpathy ◽  
Magna Manjareeka ◽  
Priyadarshini Samanta ◽  
Jayanti Mishra ◽  
...  

AbstractThe appropriateness of spirometric reference value depends on all its features matching those of the person being assessed, like ethnicity, environment, nutrition, absence of disease, measurement protocol, as well as equipment used. The present study determines the lung function parameters in normal young healthy Indians and derives reliable prediction formulae for Indian population.Computerized spirometry was done in 298 nonsmoking medical students of both genders studying in MKCG Medical College, Berhampur. All the data were statistically analyzed, and prediction equations for the young Indian population were derived.All the lung parameters showed significant gender difference. Height showed the greatest effect on the predicted value of FEVThe computed regression norms may be used to predict the spirometric values in young Indian population of similar age group as the study population.


Author(s):  
Manish Munjal ◽  
Gopika Talwar ◽  
Shubham Munjal ◽  
Tulika Saggar

Background: Different tympano meatal vascularised flaps were compared in the tympanoplastic surgery in chronic suppurative otitis media.Methods: 60 cases with diagnosis of chronic suppurative otitis media were selected from ENT OPD of Dayanand Medical College and Hospital Ludhiana. 6 types of tympanomeatal flaps were used and 10 cases of each flap were taken. The study was conducted for the period of 1 year from June 2015 to August 2016.Results: Maximum numbers of patients were in the age group of 31-40 years (26.7%), followed by age group of >50 years (23.3%). Minimum age among these patients was 11 years and maximum 65 years. Mean age was 36.67. Graft failure was in 2 patients, 1 lies under age group 31-40 years and other was in more than 50yrs group. Female patients constituted 56.7% and male patients were 43.3% in our study population. Graft uptake was 93% in females and 100% in males. In our study on 60 patients, 41 (68.3%) patients had a rural and 19 (31.7%) an urban background.Conclusions: Age does not affect the results of tympanoplasty, whatever flap maybe utilised. Awareness in rural population regarding reconstructive ear surgery is there nowadays though there is still gender discrimination, with less number of ladies opting for this elective surgery.


Author(s):  
Chitralekhya Rao ◽  
Oudeacoumar Paqurissamy ◽  
Govardhan J. ◽  
Varsha Medasani

<p class="abstract"><strong>Background:</strong> Hypermelanoses involving predominantly the face and the neck is relatively common and often presents a complex diagnostic problem. The present study titled “Clinico-epidemiological study of facial hyperpigmentation” was done in the study population of 500 patients of facial pigmentation, attending the skin outpatient department in AarupadaiVeedu Medical College and Hospital from October 2015 to September 2017.</p><p class="abstract"><strong>Methods:</strong> Aim and objective of the study was to study various clinical patterns of facial pigmentation, their clinical characteristics, their association with other pigmentary disorders and to evaluate the different etiotogical and precipitating factors. A special proforma was prepared. Patients were thoroughly interviewed and examined to find out dermatological and systemic diseases and they were subjected to investigations to evaluate different etiological factors and diagnose the clinical type of facial pigmentation.<strong></strong></p><p class="abstract"><strong>Results:</strong> The present study showed a strong female preponderance. Among the total study population there were 55% cases of melasma, 20% cases of Riehls melanosis, 10% cases of periorbital pigmentation and 5% of miscellaneous causes.</p><p><strong>Conclusions:</strong> Facial pigmentation was commonly seen in the females. 21-30 years age group was the most commonly affected age group in all types of facial pigmentation. Melasma, Riehls melanosis and periorbital pigmentation were the most common clinical types of facial pigmentation observed.</p>


Author(s):  
Pushpa Kannoujiya ◽  
Arpita Shrivastava ◽  
Tariq Ahmed Mala

Background: The study was conducted to screen women who have abnormal vaginal discharge with Pap smear to do histopathological analysis of colposcopically directed biopsies.Methods: A prospective analytical study carried out in the department of obstetrics and gynaecology. The patients were randomly selected who fulfilled the selection criteria and was carried out to study the correlation of Pap smear and colposcopy in women with unhealthy cervix.   Results: Among all patients 13% were between 20-29 years, 38% were between 30- 39%, 31% belonging to 40-49 years group and 18% was between 50-59%.  Among 100 Women studied, 33% were illiterates, 55% had primary/high school education and 12% had Higher education Majority of the patients (68.7%) of CIN occurred in the age group of 30-49years, 41.7% with CIN were paragrvida 2, 43.8% with CIN were paragravida 3 and 18.6% were greater than paragravida 4 showing high incidence of CIN in multiparity.The incidence of CIN was found to be high among the lower income group 87.5%.The major presenting complains in the study patients were white discharge per vagina.Conclusions: Colposcopy was found to be useful in understanding the morphology of the cervical lesion, both of the neoplastic and nonneoplastic ones and was very helpful in planning their management. Cytology is an accepted method for screening for cervical cancer and the value of colposcopy has been recognized. Hence it may be better to utilize cervical cytology smear with colposcopy should be offered as a diagnostic method in all patients with unhealthy cervix.


Author(s):  
Girishma J. ◽  
Rupakala B. M. ◽  
Sunil Chavan

Background: Bacterial vaginosis is the most common cause of vaginal discharge among women in reproductive age group. It is characterized by an increased vaginal pH and loss of normal lactobacilli and overgrowth of anaerobes like Gardnerella vaginalis and other gram-negative rods. Purpose of this study is to compare the characteristics of pap smear and microbiological pattern in patients with abnormal vaginal discharge.Methods: The study was conducted in the Department of Gynecology and Obstetrics of Rajarajeswari Medical College and Hospital (RRMCH) Bangalore, India. All patients with vaginal discharge were included in the study. Vaginal discharge samples were sent to gram staining, culture and pap smear examination.Results: Of the 52 patients, 18 patients (34.6%) showed positive for bacterial vaginosis according to Nugent’s score. Of the 18 patients with positive Gram stains, 8 of them were positive for bacterial vaginosis according to pap’s smear (44%) and 10 had negative pap smears. In our study, of the 18 patients with positive Gram stains, 14 (77%) of them were positive for bacterial vaginosis according to culture.Conclusions: In the present study we found out that correlation of gram stain and pap smear was 44% whereas correlation of gram stain and culture was 77%. Hence, we conclude that gram stain and culture are preferred for the diagnosis of bacterial vaginosis rather than the pap smear evaluation.


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