scholarly journals The effect of photodynamic therapy on the hematological and biochemical parameters of the blood of cats

2021 ◽  
pp. 15-17
Author(s):  
E. V. Davydov ◽  
B. V. Usha ◽  
T. O. Maryushina ◽  
M. V. Matveeva ◽  
Yu. S. Nemtseva
Keyword(s):  
Photodynamic Therapy ◽  
Standard Method ◽  
Biochemical Parameters ◽  
White Blood Cells ◽  
Blood Parameters ◽  
Effect Of Therapy ◽  
Oncological Diseases ◽  
Biochemical Analyzer ◽  
Automatic Biochemical Analyzer ◽  
Hematological And Biochemical Parameters

Relevance. In this article, we present experimental study on the effect of photodynamic therapy with a chlorin-type photosensitizer on the hematological and biochemical blood parameters of cats with malignant oncological diseases.Methods. During conducting studies in experimental animals, we took blood samples from 44 cats aged 8 to 16 years, of different breeds and different sexes, before photodynamic therapy and two days after treatment, in order to determine the possible effect of therapy on the blood counts of patients. Blood sampling was carried out according to the standard method. Hematological examination was performed on a PCE90vet analyzer (HTI, USA), biochemical on an automatic biochemical analyzer Biosystems A15 (Biosystems, Spain) and on a semi-automatic analyzer Biohaem SA (HTI, USA). Photodynamic therapy was performed according to the standard method, with the preliminary introduction of the photosensitizer “Photoditazine” at a dose of 0.8– 1 mg/kg, 3 hours before irradiation.Results. The most significant changes in the hematological study were found among the following parameters: the level of white blood cells after irradiation increased by 18%, the number of eosinophils decreased by 28%, the number of segmented neutrophils increased by 11%, the content of lymphocytes decreased by 21%. When studying the biochemical parameters of blood, changes were found in the following parameter: the glucose level increased by 13% after irradiation, the level of GGT decreased by 19% after irradiation. At the same time, all indicators of the hematological and biochemical composition of the blood were within the normal values for this type of animal. Photodynamic therapy does not significantly affect the hematological and biochemical parameters of the blood of cats, this proves the safety of using this method of treatment in these animals.

scholarly journals Study of Hematological Parameters in Children Suffering from Iron Deficiency Anaemia in Chattagram Maa-o-Shishu General Hospital, Chittagong, Bangladesh

Anemia ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Abu Syed Mohammed Mujib ◽  
Abu Sayeed Mohammad Mahmud ◽  
Milton Halder ◽  
Chowdhury Mohammad Monirul Hasan
Keyword(s):  
Iron Deficiency ◽  
Analysis Of Variance ◽  
Iron Deficiency Anemia ◽  
Biochemical Parameters ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Deficiency Anemia ◽  
Hematological And Biochemical Parameters ◽  
And Control ◽  
First Time

A total of 150 (30.61%) anemic patients out of 490 patients diagnosed to have iron deficiency anemia (IDA) have been selected for the first time in Bangladesh. For detailed study, blood samples from 150 anemic patients along with 25 controls were analyzed. Analysis of variance showed significantPvalue between mean platelet volume (MPV) in females (8.08 μm3) and males (7.59 μm3) (P<0.05) in iron deficiency anemia patients. Besides, the value of white blood cells (WBC) in males (10946.08/cmm) was significantly higher than in females (9470.833/cmm) (P<0.05). The significant correlation was observed among hemoglobin levels with hematocrits, hemoglobin with RBC, RBC with hematocrits, and MCV with MCH as well as MCH with MCHC. However, the negative correlation was observed between the hematological variables neutrophils and lymphocytes (r=-0.989). The common complaints we have found in the survey were weight loss 73.33%, attention problem 68%, dyspepsia 65%, decrease of appetite 72%, weakness 68%, diarrhea 65%, and headache 55% among IDA patients. ANOVA showed significant statistical difference in all the hematological and biochemical parameters. Analysis of variance test between anemias with only one of three biochemical parameters decreased and control showed that this group does not have iron deficiency.

scholarly journals Assessment of Haematological and Biochemical Parameters of Women at Childbirth and their Newborn in Abidjan, Côte d’ Ivoire

2020 ◽  
Vol 1 (2) ◽  
pp. 91-108
Author(s):  
Mathieu Nahounou Bleyere ◽  
Jean-Baptiste N'Guessan Oussou ◽  
Jean Paul Aristide Amani ◽  
Paul Angoué Yapo
Keyword(s):  
Nutritional Status ◽  
Biochemical Parameters ◽  
Blood Parameters ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Normocytic Anaemia ◽  
Hematological And Biochemical Parameters ◽  
Almost All ◽  
The Impact ◽  
Lipid Parameters

Purpose: The objective of this study is to compare the hematological and biochemical parameters in women with those of their newborns in order to assess the impact of the nutritional status of the former on the latter. Study Design: A cross sectional and prospective study. Subjects and Methods: The study was conducted on 83 women who came to give birth in the hospitals of Abobo Sud (from April 3 to 20, 2017) and Yopougon Attié (from December 19, 2017 to January 18, 2018). The recruitment was based on their consent and according to specific inclusion and exclusion criteria. The blood, taken from the elbow’s vein of the women in labor and in the umbilical cord after childbirth, is put in suitable tubes for the assays of the blood parameters. Results: The results showed that 29% of women in childbirth and 41% of newborns were anemic with the occurrence of almost all forms of anemia such as Normochromic Normocytic Anaemia (ANN), Normochromic Microcytic Anaemia (ANm) and Hypochromic Normocytic Anaemia (AHN), in both groups. The glycemia and lipid parameters studied as well as the atherogenicity indices were increased in women during childbirth, unlike newborns. Regarding hepatic and renal parameters, no significant differences were observed in total proteins, Alanine aminotransferase (ALT) and total bilirubin between women and newborns. However, the other parameters such as creatinine, Aspartate aminotransferase (AST) and conjugated bilirubin were elevated in newborns. As for the blood ion levels, the results showed high levels of calcium and potassium in newborns and high levels of chlorine in women. Conclusion: Women nutritional status significantly influences that of their newborn babies.

scholarly journals Exposure of gasoline professionals to leaded gasoline in Asyut governorate

2015 ◽  
Vol 4 (2) ◽  
pp. 200
Author(s):  
Hatem Ahmed ◽  
Shaaban M. Ahmed
Keyword(s):  
Biochemical Parameters ◽  
Blood Lead Level ◽  
Venous Blood ◽  
Lead Level ◽  
White Blood Cells ◽  
Blood Lead ◽  
Automotive Gasoline ◽  
Unleaded Gasoline ◽  
Hematological And Biochemical Parameters ◽  
Total Sales

<p><strong>Background:</strong> Gasoline is a complex manufactured mixture that does not exist naturally in the environment and produced from petroleum in the refining process. Gasoline discussed in this profile is automotive gasoline used as a fuel for engines in automobiles and other vehicles. Unleaded gasoline was introduced in the greater area Asyut, and 10% of the total sales of gasoline were unleaded. There were no previous studies on pollution caused by gasoline exposure in Asyut governorate in Upper Egypt, so, in this study we try to concern on the effect of air pollution from automobile exhaust on hematological and biochemical parameters of professionals.</p><p><strong>Materials and methods:</strong> Hundred and twenty samples from professionals have been collected from Asyut Governorate; they divided into four groups each group contain thirty samples. 10 milliliter of venous blood sample was withdrawn, over EDTA, from each individual, to determine the values of hematological, biochemical parameters and blood-lead level.</p><p><strong>Results and discussion:</strong> According to the present study, it was found that there was a significant increase in blood-lead level, hemoglobin levels and white blood cells count in all of the exposed groups. On the other hand, creatinine level shows significant decrease but there were a significant increase urea level and increase in some liver function's levels (ALT and AST) in all tested groups.</p><p><strong>Conclusion:</strong> The exposure to gasoline caused some toxic lesions on some parameters (hematological and biochemical). It is also observed that enzyme activity (AST, ALT) increase significantly compared with control.</p>

scholarly journals EFFECT OF THE "UNICOCCIDUM" ON HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS OF PIGLETS

2020 ◽  
pp. 496-501
Author(s):  
Cheskidova ◽  
Shelyakin ◽  
Bliznetsova ◽  
Semenov
Keyword(s):  
Therapeutic Dose ◽  
Biochemical Parameters ◽  
Clinical Status ◽  
White Blood Cells ◽  
New Drugs ◽  
Clinical State ◽  
Control Group ◽  
Group I ◽  
Negative Effect ◽  
Hematological And Biochemical Parameters

For the treatment of eimeriosis, drugs that are different in their chemical structure and direction of action are used, which can have a negative effect on productive animals. When conducting preclinical studies of new drugs, we carried out a study of the harmlessness (tolerance) of the drug Unicoccidum in piglets. Healthy of 2 months old animals (n = 18) were selected for this purpose. Piglets of group I – for the control, they didn’t receive the drug. Animals of group II were orally individually administered Unicoccidum at a dose of 2.0 ml/kg (therapeutic dose), and III group – at a dose of 10.0 ml/kg (5-fold therapeutic dose). The toxic effect of the drug was evaluated by the clinical state of the animals, hematological (erythrocytes, hemoglobin, white blood cells, leukogram) and biochemical parameters (total protein, urea, creatinine, AST, ALT, AP, γ-GT, cholesterol, glucose, total calcium, inorganic phosphorus). It was found that the use of Unicoccidum in the studied doses did not have a negative effect on the clinical status of piglets. Single administration of Unicoccidum at doses of 2.0 ml/kg and 10.0 ml/kg did not significantly differ in hematological and biochemical parameters of piglets' blood from animals from the control group, and the fluctuations in the values of these indicators were within the physiological norm for this animal species. This can serve as a proof of its good tolerance and harmlessness.

Influence of feed additives on the hematological and biochemical parameters of the blood of lactating cows

2022 ◽  
pp. 27-33
Author(s):  
R. A. Maksimova ◽  
◽  
E. M. Ermolova ◽  
V. I. Kosilov ◽  
Yu. A. Karmatskikh ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Live Weight ◽  
Blood Parameters ◽  
Feed Additives ◽  
The Body ◽  
Farm Animals ◽  
Feed Additive ◽  
Main Task ◽  
Lactating Cows ◽  
Hematological And Biochemical Parameters

Increasing the milk productivity of cows is the main task facing the livestock industry of our country. The study of some hematological and biochemical blood parameters in dairy cows when different feed additives are included in their rations is an urgent research task. The purpose of the investigations was to study the hematological and biochemical parameters of the blood of lactating cows when using different feed additives in the ration. During the investigations, the influence of feed additives such as Zaslon 2+ (at a dose of 20 g/head/day to the main ration), Diatomite (100 g/head/day to the main ration) and Monosporin (70 g/head/day to the main ration) on the hematological and biochemical blood parameters of lactating cows has been observed. The studied feed additives are used for the adsorption of mycotoxins in feed, normalization of digestive processes, and improvement of the livability and productivity of farm animals. In order to study the influence of the tested feed additives on the hematological parameters of the blood of lactating cows under the conditions of the Troitsky area in the Chelyabinsk region, on four groups of cows selected according to the principle of analogues (age, live weight, productivity, breed, physiological condition) the scientific and economic experiment has been carried out. As the result of the investigations, data have been obtained indicating that the feed additive Zaslon 2+ at the dose of 20 g/head/day has the greatest effect on the metabolism in the body of lactating cows.

scholarly journals The influence of hypothermia prevention by application of skin moisture absorbent on the value of body temperature, body weight and blood parameters in piglets

2021 ◽  
Vol 73 (5) ◽  
pp. 1058-1066
Author(s):  
M. Mirkov ◽  
I. Radović ◽  
M. Cincović ◽  
M. P. Horvatović ◽  
S. Dragin
Keyword(s):  
Body Weight ◽  
Body Temperature ◽  
Biochemical Parameters ◽  
Blood Parameters ◽  
Economic Losses ◽  
Control Group ◽  
Pig Production ◽  
Hematological And Biochemical Parameters ◽  
Moisture Absorbent ◽  
Skin Moisture

ABSTRACT Reducing the mortality rate is of a great economic importance for pig farming. Therefore, it is necessary to define the conditions in the farrowing unit based on the performance of the piglets, and specific hematological and biochemical parameters. Therefore, the aim of this paper is to examine the importance of using skin moisture absorbent and its influence in preventing hypothermia, which causes great economic losses in pig production. The experiment was set up on a commercial farm in Serbia and included 92 pigs divided into the experimental and control group. Body temperature values, body weight and blood parameters were monitored. The obtained values indicate that there is a significantly positive correlation of body temperature change and body weight values, and body temperature showed a significantly higher increase in the experimental group compared to the control group. The results obtained from hematological and biochemical parameters provide a clearer picture of the metabolic processes in piglets in the farrowing unit and can be used to further improve pig production and as a complement to genetic enhancement.

scholarly journals Effects of gentaminoseleferon on blood parameters during treatment of Mycoplasma dispar respiratory infection in calves

2020 ◽  
Vol 13 (10) ◽  
pp. 2197-2202
Author(s):  
Mohammad Abed Alhussen ◽  
Hamdan Naef ◽  
Yury Anatolyevich Vatnikov
Keyword(s):  
Therapeutic Efficacy ◽  
Biochemical Parameters ◽  
Respiratory Diseases ◽  
Clinical Signs ◽  
Blood Parameters ◽  
Total Serum ◽  
Economic Damage ◽  
Control Group ◽  
Hematological And Biochemical Parameters ◽  
Experimental Group

Background and Aim: Respiratory diseases in young cattle are among the significant cattle pathologies that cause considerable economic damage globally. For the treatment of respiratory diseases, coformulated drugs that increase general nonspecific resistance, exhibit adaptogenic and anti-inflammatory properties, and normalize metabolic processes in animals are currently being used. The aim of our study was to investigate the therapeutic efficacy of the complex drug "gentaminoseleferon", used in the treatment of respiratory diseases in calves, especially in Mycoplasma dispar infection. Materials and Methods: The animals were divided into three groups. Calves with the first clinical signs of respiratory pathology were randomly divided into two groups. The first experimental group (n=5) was intramuscularly injected with sulfetrisan at a dose of 5-10 mL/animal once per day for 7 days. The second experimental group (n=5) was given gentaminoseleferon at a dose of 1 mL/10 kg of body weight once per day for 7 days. The drugs were not used in the control group, the "healthy animals (n=5)". Blood samples were taken 10 days before and after treatment and compared between the experimental and healthy calves. The changes in the hematological and biochemical parameters of blood and serum were evaluated. Results: During the recovery process of animals in the experimental groups, a normalization of the hematological and biochemical parameters of blood and serum was noted. Interestingly, in calves of the second experimental group, an increase in the total serum protein content by 2.2% (p<0.05) was recorded in comparison with the first group. The second group, furthermore, showed an increase in Vitamins A, E, and C concentrations by 13.5% (p<0.05), 11.9% (p<0.005), and 15.1% (p<0.0005), respectively, as well as in zinc and iron concentrations by 4.1% (p<0.05) and 9.3% (p<0.0001), respectively. These findings indicate a more pronounced decrease in the inflammatory process in the respiratory system and intensive restoration of metabolism, thereby establishing the high therapeutic efficacy of gentaminoseleferon. Conclusion: Gentaminoseleferon was proven highly effective in the treatment of calves with respiratory illnesses and in restoring homeostasis in the organisms of animals after treatment, as indicated by the normalization of morphological and biochemical blood parameters with a reduction in the recovery time.

scholarly journals Blood parameters in fattening pigs from two genetic types fed diet with three different protein concentrations1

2018 ◽  
Vol 2 (4) ◽  
pp. 372-382 ◽  
Author(s):  
Fabio Abeni ◽  
Francesca Petrera ◽  
Aldo Dal Prà ◽  
Luca Rapetti ◽  
Gianni Matteo Crovetto ◽  
...  
Keyword(s):  
Total Bilirubin ◽  
Protein Profile ◽  
White Blood Cells ◽  
Experimental Period ◽  
Blood Parameters ◽  
Tartrate Resistant Acid Phosphatase ◽  
Large White ◽  
Plasma Urea ◽  
Conventional Diet ◽  
Hematological And Biochemical Parameters

Abstract The study aimed to evaluate possible differences between two genetic groups (GG) of pigs, fed diets varying in dietary CP level, in hematological and biochemical plasma profiles. The study was carried out in an experimental farm and involved 36 barrows (average BW 129 ± 11 kg) from two GG: group A (18 Italian Duroc boars × Italian Large White sows) and group D (18 DanBred Duroc), fed three experimental diets: a conventional diet and two low-protein diets (LP1 and LP2). A digestibility/balances trial was carried out on 12 pigs A and 12 pigs D that were housed individually in metabolic cages during four digestibility/balances periods. The experimental design was a factorial design, with 3 diets × 2 GG × 4 periods. The experiment lasted 56 d. Blood was sampled from jugular vein in the morning before feed distribution from all barrows in pens at the start and the end of the experimental period; a supplementary blood sample was collected from the 24 pigs at the end of the four digestibility periods (six pigs per period). Blood was analyzed for hematological and biochemical parameters and serum protein profile using automated analyzers. The GG D showed lower white blood cells (WBC), lymphocyte, and monocyte counts than A group. The GG affected several plasma metabolite concentrations: triglycerides, creatinine, Cl, Fe, alkaline phosphatase, and tartrate-resistant acid phosphatase activities were higher in D groups, while urea, albumin, Ca, Na, total bilirubin, and albumin as percentage of total protein were lower than A group. On the contrary, the dietary protein level neither affects WBC nor their populations; only a trend was reported for erythrocytes (red blood cell) and platelets. The diet affected only plasma urea and total bilirubin concentrations.

scholarly journals Hematological and Serum Biochemical Reference Values for the Posavina and Croatian Coldblood Horse Breeds

2014 ◽  
Vol 64 (2) ◽  
pp. 200-212 ◽  
Author(s):  
Lana Pađen ◽  
Tomislav Gomerčić ◽  
Martina Đuras ◽  
Haidi Arbanasić ◽  
Ana Galov
Keyword(s):  
Clinical Diagnosis ◽  
Reference Values ◽  
Environmental Conditions ◽  
Biochemical Parameters ◽  
Blood Parameters ◽  
Specific Reference ◽  
Harsh Environment ◽  
Serum Biochemical ◽  
Hematological And Biochemical Parameters ◽  
The Way

Abstract In this study the hematological and biochemical parameters in the blood of indigenous Croatian working horse breeds were investigated. The Posavina and Croatian Coldblood horses are adapted to harsh environmental conditions and their blood parameters might differ from other horse breeds. The study was carried out on 100 mares and 12 stallions of ages from 2 to 19 years. Fifteen hematological and 19 biochemical parameters were analysed. Values of 22 parameters showed considerable overlapping with values obtained for other horse breeds, and substantial resemblance is evident with values reported for Pakistani working horses. Several reference values showed statistically significant effect of sex (Hb, ALB, CREA, TBIL and Ca where significantly higher in stallions; EOS, CK, ALP, UREA and Mg were significantly higher in mares). None of the parameters studied showed any differences associated with age. The adaptation of Posavina and Croatian Coldblood horses to the harsh environment of flooded pastures and the way of breeding might be reflected in their specific reference values. The obtained results enabled the establishment of hematological and biochemical reference values in the blood of Posavina and Croatian Coldblood horses that will in turn support clinical diagnosis and further research into horse physiology.

scholarly journals The effect of plant hormone indoleacetic acid (IAA) on hematological and biochemical parameters in mice

1970 ◽  
pp. 5-8 ◽  
Author(s):  
MH Morshed ◽  
M Shamm Hossain ◽  
M Anwar Habib ◽  
MM Moinuddin Ahmed ◽  
M Ibrahim ◽  
...  
Keyword(s):  
Blood Cells ◽  
Biochemical Parameters ◽  
Plant Hormone ◽  
Indoleacetic Acid ◽  
White Blood Cells ◽  
Control Group ◽  
Differential Count ◽  
General Observation ◽  
Hematological And Biochemical Parameters ◽  
Serum Glutamate

The subacute toxicity of plant hormone indoleacetic acid (IAA) was studied on Swiss albino mice. The studies include the gross general observation such as changes in body weight, hematological profiles [total count of red blood cells (RBC) and white blood cells (WBC), differential count of WBC, platelet count, hemoglobin (Hb)%], biochemical parameters of blood [serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), serum alkaline phospatase(SALP), creatinine] and histopathology of the liver, kidney, lung, spleen, heart and brain of both control and experimental day-1 for consecutive 14 days, showed no significant change of hematological and biochemical parameters. No abnormalities were also found in the histopathology of the liver, kidney, lung, spleen, heart and brain in the experimental group of animals following same dose when compared with control group. This preliminary toxicological study suggests that the plant hormone indoleacetic acid (IAA) may be used safely for agricultural purposes and as an external preservative DOI: 10.3329/bjpp.v22i1.3561 Bangladesh J Physiol Pharmacol 2006; 22(1/2) : 5-8  

Sign in / Sign up

Export Citation Format

Share Document