scholarly journals System of antioxidant protection of the body of piglets under the action of feed additive “Butaselmevit-plus”

2021 ◽  
Vol 4 (2) ◽  
pp. 38-43
Author(s):  
T. V. Martyshuk ◽  
B. V. Gutyj ◽  
V. I. Khalak
Keyword(s):  
Body Weight ◽  
Antioxidant Defense ◽  
Vena Cava ◽  
Antioxidant Defense System ◽  
The Body ◽  
Feed Additive ◽  
Before And After ◽  
Experimental Group ◽  
Technological Stress ◽  
Protective Systems

The aim of the study was to investigate the effect of the feed additive “Butaselmevit-plus” on the state of the antioxidant defense system of piglets during weaning. The experiments were conducted on the basis of the LTD “KOSHET” Mukachevo district of Zakarpattia region. Two groups of piglets were formed – control and experimental, in the amount of 10 individuals in each group, selected on the principle of analogs – age, breed and body weight. Animals were fed according to the norms for this age of pigs. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests for further maintenance during fattening and rearing with a change in the structure of the diet, which served as technological stress for the animal's body. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed additive “Butaselmevit-plus” at a dose of 100 mg/kg body weight per day. The material for the study was blood, which was taken in the morning before feeding the animals by puncture of the cranial vena cava for 20 days of life (the period before weaning), for 25 days of life (the period before weaning), for 30 days of life (2 days after weaning), for 35 days of life (7 days after weaning), 40 days of life (12 days after weaning). It is proved that feeding piglets feed additive “Butaselmevit-plus” enhanced the antioxidant status of piglets after weaning. It was found that under conditions of technological stress, the use of feed additive “Butaselmevit-plus” in the amount of 100 mg/kg body weight per day improves the antioxidant defense of the body, as evidenced by an increase in blood 35-day-old piglets superoxide dismutase activity by 26.7 % (P < 0.001), catalase – by 39.5 % (P < 0.001), glutathione peroxidase – by 51.7 % (P < 0.05), glutathione reductase – by 52.9 % (P < 0.05), the content of reduced glutathione – at 58.3 % (P < 0.001). These results confirm the effectiveness of the use of milk thistle, methionine, selenium, and vitamins A, E, and D3 in the feed additive “Butaselmevit-plus” to piglets in the period before and after weaning to activate the protective systems of their body.

scholarly journals System of antioxidant protection of the body of piglets under the action of feed additive “Sylimevit”

2021 ◽  
Vol 23 (104) ◽  
pp. 10-17
Author(s):  
L. V. Vyslotska ◽  
B. V. Gutyj ◽  
O. V. Kozenko ◽  
V. I. Khalak ◽  
M. V. Chornyj ◽  
...  
Keyword(s):  
Body Weight ◽  
Antioxidant Defense System ◽  
Feed Additives ◽  
The Body ◽  
Biologically Active ◽  
Feed Additive ◽  
Free Access ◽  
Direct Acting ◽  
Active Substances ◽  
Technological Stress

One of the conditions for obtaining high-quality pig products is the use of feed additives, which contain all the necessary biologically active substances, eliminating their deficiency in feed and acting as catalysts for metabolic processes in pigs. That is why the aim of the study was to study the effect of feed additive “Sylimevit” on the enzymatic and non-enzymatic parts of the antioxidant system of piglets after weaning. Two groups of piglets were formed – control and experimental, in the amount of 10 individuals in each group, selected on the principle of analogues – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. Feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. Feeding piglets Silimevit feed enhances their antioxidant status. The use of this feed additive in piglets contributed to the activation of both enzymatic and non-enzymatic parts of the antioxidant defense system of piglets after weaning, as indicated by an increase in blood 35-day-old piglets superoxide dismutase activity by 26.9 % (P < 0.001), catalase – 41.1 % (P < 0.001), glutathione peroxidase – by 52.7 % (P < 0.05), glutathione reductase – by 53.5 % (P < 0.05), the content of reduced glutathione – by 75 % (P < 0.001). This is due to the fact that silimevit contains active substances such as milk thistle and vitamins, which are strong direct-acting antioxidants and directly interact with free radicals and reactive oxygen species.

scholarly journals «Energosil» in the diets of replacement gilts

2019 ◽  
Vol 20 (2) ◽  
pp. 153-162
Author(s):  
A. A. Suvorov ◽  
в Sh. Gayirbegov ◽  
A. S. Fedin ◽  
A. M. Guryanov
Keyword(s):  
Body Weight ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Practical Training ◽  
Optimal Dosage ◽  
Growth Energy ◽  
Experimental Group

The article gives scientific substantiation of using silicon-containing new feed additive “Energosil” for replacement gilts. The studies were conducted in pig-breeding complex of the Center for Practical Training of Agricultural Specialists in Mordovia Republic. There were three experimental groups of replacement gilts (10 animals each). The effect of various dosages of Energosil (5.0, 7.5, and 10 mg per kg of body weight) on digestibility, nutrient utilization, and animal growth energy was studied. The most optimal dosage of a new feed additive in their rations was revealed, which constituted 5 mg / kg of the animal live weight. It was established that the animals from the first experimental group, who received silicon-containing feed additives of this amount digested the nutrients of the diet better than their counterparts from the other groups. Compared to the control group, the digestibility of dry matter increased by 3.62% (p<0.05), organic matter by 3.29% (p<0.01), crude protein by 4.09% (p<0.001), fat by 4.30% (p<0.01), cellulose by 3.79% (p<0.01) and nitrogen-free extractives by 2.03% (p>0.05).Replacement gilts of the first experimental group, who were given Energosil in the amount of 5 mg / kg body weight in addition to the basic ration, retained nitrogen in their bodies by 17.1%, calcium by 55.9% and phosphorus by 69.7% more than their counterparts from the control group. It contributed to an increase in body weight of gilts from the first group compared to control counterparts by 10.8%. Increased dosages of Energosil (7.5 and 10 mg / kg body weight) also had a better effect on the growth energy of gilts compared with the control group. The feed additive in the amount of 7.5 mg kg of animal  live weight contributed to an increase in animal weight compared with control counterparts by 6.21 kg or 4.8% (p<0.05), with a third experimental group by 4.4 kg or by 3.4% (p<0.05). When given Energosil in the dosage of 10 mg/kg, the body weight of gilts from the third experimental group was higher by 1.81 kg or 1.4% (p> 0.05) compared with the control counterparts.

scholarly journals effect of ascorbic acid as a feed additive on indicators of the reproductive performance of Pulawska breed gilts

2016 ◽  
Vol 72 (6) ◽  
pp. 378-382
Author(s):  
Jerzy Lechowski ◽  
Anna Kasprzyk ◽  
Mirosław Tyra ◽  
Beata Trawińska
Keyword(s):  
Body Weight ◽  
Vitamin C ◽  
Reproductive Performance ◽  
Reproductive Organs ◽  
The Body ◽  
Reproductive Value ◽  
Feed Additive ◽  
Corpora Lutea ◽  
Reproduction Cycle ◽  
Experimental Group

The aim of the study was to determine the effect of vitamin C on indicators of gilts and sows reproductive value. The study was conducted using 64 gilts of the Pulawska breed. The experimental gilts received a supplement of vitamin C in an amount of 2.4 g daily throughout the whole experiment. Sixteen gilts from both control and experimental groups were mated in their third estrus. In order to determine the number of corpora lutea and the state of development of the reproductive organs, other gilts from the control and experimental groups were slaughtered after third estrus between the 5th and 10th day of the following estrous cycle. The results showed that gilts from the experimental group were characterized by higher potential fertility, as well as reared more piglets per litter. In the body weight and backfat thickness of sows during the first reproduction cycle in the control and experimental groups were not statistically significantly different. The piglets in the experimental group had higher body weight in the 1st and 21st day of rearing. Larger contents of protein, immunoglobulins, and vitamin C were recorded in the colostrum and milk from experimental sows.

scholarly journals State of antioxidant protection system in carp hepatopancrease affected by associative Aeromonas Hydrophila infection with Saprolegnia Sp.

2020 ◽  
pp. 85-89
Author(s):  
Kh. Ya. Solopova ◽  
◽  
O. I. Vishchur ◽  
M. Z. Korylyak ◽  
I. Ye. Solovodzinska ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Aeromonas Hydrophila ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
The Body ◽  
Control Group ◽  
Research Station ◽  
Defense System ◽  
Peroxidation Processes ◽  
Experimental Group

Bacterial diseases are responsible for heavy mortality in both wild and cultured fish. Co-infections are very common in nature and occur when hosts are infected by two or more different pathogens either by simultaneous or secondary infections so that two or more infectious agents are active together in the same host. Associative infections pose a significant threat to fish farming, so it is necessary to develop effective means of prevention and treatment of these infections; it is advisable to study in detail their impact on various fish. The aim of the study was to determine the intensity of lipid peroxidation processes and the activity of the antioxidant defense system in the body of carp suffering from aeromonosis and the associated infection of aeromonosis with saprolegniosis. The research was conducted at the Lviv Research Station of the Institute of Fisheries of NAAS. There were three groups of fish, 5 in each. The control group consisted of clinically healthy fish, the first experimental group (D1) – carps affected by Aeromonas hydrophila infection, the second experimental group (D2), which consisted of carps affected by associative Aeromonas hydrophila infection with Saprolegnia Sp. The results of studies have shown that carp with associative infection ‒ of Aeromonas hydrophila infection with Saprolegnia Sp. leads to the activation of lipid peroxidation processes, especially the primary product of LPO. Thus, in the hepatopancreas of fish there was an increase of 1.4 (p <0.05) in the reasonable content of diene conjugates and there was a tendency to increase the content of TBA-active products. At the same time, the inhibitory effect of pathogenic factors of this disease on the activity of the enzymatic link of the antioxidant defense system was stated. In particular, carp patients with associative infection ‒ of Aeromonas hydrophila infection with Saprolegnia Sp. had higher catalase and superoxide dismutase activity, respectively, 1.3 (p <0.05) and 2.3 (p <0.01) times. The results of experimental studies made it possible to expand and deepen the mechanisms of the pathogenesis of the co-infection of Aeromonas hydrophila infection with Saprolegnia Sp. and to use the data to develop effective treatments.

MORPHOLOGICAL INDICATORS OF BLOOD, RESISTANCE OF THE ORGANISM AND MEAT PRODUCTIVITY OF PIGLET AT APPLICATION OF 20-HYDROXYEXDISONE

2020 ◽  
Vol 1 (3) ◽  
pp. 371-377
Author(s):  
A.G. Solovieva ◽  
◽  
K.T. Erimbetov ◽  
O.V. Obvintseva ◽  
◽  
...  
Keyword(s):  
Blood Plasma ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
The Body ◽  
Natural Resistance ◽  
Defense System ◽  
Growing Period ◽  
Meat Productivity ◽  
Experimental Group ◽  
In Blood Plasma

The effectiveness of using 20-hydroxyecdysone in the diet of piglets during the growing period and its effect on the formation of natural resistance, the antioxidant defense system of the body and their meat productivity were studied. The introduction of 20-hydroxyecdysone into the diet at the rate of 30 mg per kg of feed positively influenced on the bactericidal and lysozyme activity of blood serum, which in the experimental group were higher by 12,9 and 14,0%, respectively, compared with the control. The activity of superoxide dismutase and catalase enzymes in blood plasma in piglets of the experimental group was statistically significantly higher compared to the control. On the contrary, the content of malondialdehyde in blood plasma was statistically significantly lower in piglets of the experimental group compared with the control (17,1%, P≤0,01). In piglets of the experimental group, in comparison with the control, the output of muscle tissue (by 5,3%, P≤0,01), the area of the “muscle eye” (34,5%, P≤0,05) was statistically significantly higher, with less adipose tissue outlet.

scholarly journals Effect of Germinated Pigmented Rice “Superjami” on the Glucose Level, Antioxidant Defense System, and Bone Metabolism in Menopausal Rat Model

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2184
Author(s):  
Soo Im Chung ◽  
Tae-ho Ham ◽  
Mi Young Kang
Keyword(s):  
Body Weight ◽  
Bone Metabolism ◽  
Glucose Level ◽  
Rat Model ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Rice Cultivar ◽  
The Body ◽  
Defense System ◽  
Pigmented Rice

Women experience physical, mental, and social changes during menopause. It is important to maintain a healthy diet for effective menopause management. The effect of germinated Superjami, a deep violet colored rice cultivar, on the body weight, glucose level, antioxidant defense system, and bone metabolism in a menopausal rat model was investigated. The animals were randomly divided into three groups and fed with a normal diet (ND), a control diet supplemented with 20% (w/w) non-germinated Superjami flour (NGSF), or germinated Superjami flour (GSF) for eight weeks. The NGSF and GSF groups exhibited significantly lower body weight and fat, glucose and insulin contents, adipokine concentrations, and bone resorption biomarker levels, and higher antioxidant enzyme activities and 17-β-estradiol content than the ND group (p < 0.05). The GSF group showed greater glucose homeostasis, antioxidative, and bone metabolism-improving effects compared with the NGSF group. These findings demonstrate that germination could further improve the health-promoting properties of Superjami and that this germinated pigmented rice cultivar could be useful in the treatment and management of menopause-induced hyperglycemia, oxidative stress, and bone turnover imbalance.

scholarly journals Growth and development dynamics of Hyplus meat breed of young rabbits under the influence of «Humilid» feed additive

2020 ◽  
pp. 96-101
Author(s):  
V. A. Utkina ◽  
◽  
L. M. Stepchenko ◽  
Keyword(s):  
Body Weight ◽  
Growth And Development ◽  
Physiological State ◽  
The Body ◽  
Biologically Active ◽  
Daily Weight Gain ◽  
Feed Additive ◽  
Control Group ◽  
Age Related ◽  
Experimental Group

The research objective is to establish Hyplus meat breed of young rabbits and to determine growth and development characteristics during the period from weaning to slaughter age under conditions of the biologically active feed additive of humic nature «Humilid» introducted into their general diet. The control and experimental groups of animals were formed according to the principle of similar groups. Experiment study lasted for 35 days, including 7 days preparatory period, 21 days research period and 7 days aftereffect period. The young rabbits of the control and experimental groups were fed with the main diet, which included compound feed with an individual calculation of nutrients per animal. The young rabbits of the experimental group were additionally injected with a biologically active feed additive «Humilid» in the form of an aqueous solution in an amount of 5 mg/kg of body weight according to the active substance to the main diet for 21 days. During the experiment, the effect of «Humilid» on the growth and development of young rabbits and their physiological state was studied. The weighing of young rabbits in the experimental groups was carried out once a week. At the same time, their body weight was determined on average and average daily growth, the safety of the livestock, in addition, the weight and mass index of the liver, heart and kidneys after slaughter by the calculation method. With the introduction of the feed additive «Humilid» to young rabbits, an increase in the body weight of the animals is observed throughout the experiment. The body weight on average of young animals of the experimental group exceeded this indicator in comparison with animals in the control group by 17.2 % (p˂0.001). Under the conditions of the introduction of the biologically active feed additive «Humilid» over the period of the experiment, the average daily weight gain of young rabbits in the experimental group was higher by 20.7 % (p˂0.01) compared to this indicator in the animals of the control group, respectively. The safety of the livestock was 100% in both groups. However, it should be noted that young rabbits of the control group had more pronounced motor activity and signs of anxiety than the animals of the experimental group, which obtained the feed additive of humic nature «Humilid». When «Humilid» was used in the diet, the mass of organs and the index of their development in young rabbits in the experimental and control groups of animals were within the range of age-related changes, which indicates the non-toxic effect of this additive.

scholarly journals The level of products of lipid peroxidation in the blood of piglets at the action feed additive “Sylimevit”

2021 ◽  
Vol 23 (95) ◽  
pp. 154-159
Author(s):  
L. V. Vyslotska ◽  
B. V. Gutyj ◽  
V. I. Khalak ◽  
T. V. Martyshuk ◽  
V. B. Todoriuk ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Body Weight ◽  
Feed Additive ◽  
Free Access ◽  
Lipid Hydroperoxides ◽  
Adaptive Responses ◽  
Peroxidation Processes ◽  
Weaning Piglets ◽  
Experimental Group ◽  
Technological Stress

Intensive pig breeding has been reported in the literature to suggest that early weaning of piglets from sows is an extreme stimulus that reduces the protective and adaptive responses of piglets. That is why the aim of the study was to study the effect of the feed additive “Sylimevit” on the level of lipid peroxidation products of piglets after weaning. Two groups of piglets were formed – control and experimental in the amount of 10 individuals in each group, selected on the principle of analogs – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. While feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. The technological stress of weaning piglets from sows is accompanied by a gradual probable intensification of lipid peroxidation processes. Feeding Sylimevit feed to piglets after weaning helped to reduce the content of intermediate and final products of lipid peroxidation: lipid hydroperoxides – by 52 % (P < 0.001) and TBA-active products – by 22.5 % (P < 0.01). Thus, feeding the piglets of the experimental group of the feed additive “Sylimevit” helped to suppress the processes of lipid peroxidation in animals. Thus, the results of the use of feed additive “Sylimevit” in weaned piglets showed a pronounced antioxidant effect. The components of the feed additive directly interacted with reactive oxygen species and free radicals, preventing the development of oxidative stress.

scholarly journals The Influence of Highly Dispersed Metal Forms on Calcium and Phosphorus Metabolism in Polygastric Animals

2022 ◽  
Author(s):  
Makaeva Ayna Maratovna ◽  
Sizova Elena Anatolevna ◽  
Atlanderova Ksenya Nikolaevna
Keyword(s):  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Utilization Rate ◽  
Control Group ◽  
Ruminal Fluid ◽  
Group I ◽  
Calcium And Phosphorus ◽  
Group Ii ◽  
Experimental Group

Determining which forms of mineral feed additives can increase farm animal productivity is a key area of research. This study assessed the mineral composition of ruminal fluid and the effectiveness of calcium and phosphorus used by animals after the introduction of finely dispersed particles (FDP) of SiO2 (group I) and FeCo (group II) with a hydrodynamic radius of 109.6 ± 16.6 and 265 ± 25 nm, respectively. The deposition and use of calcium and phosphorus in the body of the experimental animals exceeded the control values. In group I, 30.8% more calcium was deposited (p ≥ 0.05), and in group II, the value was 30.3% (p ≥ 0.01). In the experimental groups, the calcium utilization rate was 27.3% higher in group I (p ≥ 0.05), and 28.2% higher in group II (p ≥ 0.01) compared to in the control. Phosphorus deposition was 34% higher (p ≤ 0.01) in experimental group I and 6% higher in experimental group II, compared with the control. Group I had a high utilization rate of phosphorus from the feed (with a 29% difference compared to the control). Comparison of the experimental groups revealed that the introduction of SiO2 FDP promoted an increase in the concentration of silicon, phosphorus, and calcium in the ruminal fluid. The introduction of FeCo FDP was accompanied by a decrease in the concentration of iron and cobalt in the ruminal fluid. Thus, the use of feed additive in finely dispersed form in the diet of animals was accompanied by an increase in the use of calcium and phosphorus by the animal’s body, which is advisable when intensifying milk and meat productivity. The obtained results require further research. Keywords: finely dispersed forms of microelements, ruminants, calcium and phosphorus exchange, feeding

scholarly journals INFLUENCE OF «METISEVIT» ON THE ACTIVITY OF ENZYME AND NONENZYME LINK OF ANTIOXIDANT PROTECTION UNDER THE BULL’S BODY CADMIUM LOADING

2016 ◽  
Vol 18 (2(66)) ◽  
pp. 52-59
Author(s):  
B.V. Gutyj ◽  
Y. Lavryshyn ◽  
V. Binkevych ◽  
O. Binkevych ◽  
О. Paladischuk ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Superoxide Dismutase ◽  
Vitamin E ◽  
Glutathione Peroxidase ◽  
Antioxidant Defense ◽  
Cadmium Stress ◽  
Antioxidant Defense System ◽  
The Body ◽  
Antioxidant Protection ◽  
Young Cattle

The article contains the research results of the effect of cadmium chloride on the indexes of enzyme and nonenzyme systems of  antioxidant defense system in young cattle, such as the activity of catalase, superoxide dismutase, glutathione peroxidase, glutathione levels of vitamins A and E. It is established that feeding calves at a dose of toxicant 0.04 mg / kg activity of catalase, superoxide dismutase, glutathione peroxidase, glutathione levels of vitamins A and E in the blood of experimental animals decreased throughout the experiment. The lowest indicators of antioxidant in the blood of young cattle is set on the twenty -fourth day of the experiment, which is associated with increased activation of lipid peroxidation and the balance between antioxidant system and lipid peroxidation intensity. Given the cadmium load of young cattle it is used a new integrated drug with antioxidant action «Metisevit», which includes metifen, sodium selenite and vitamin E wich is founded as stimulating effects on the activity of antioxidant protection. In particular,it is established probable increase in activity of catalase, superoxide dismutase, glutathione peroxidase, glutathione levels, vitamin A and vitamin E in the blood of young cattle, which has performed cadmium stress. These changes occur through comprehensive action components of the drug «Metisevit» that leads to the normalization of metabolic processes and free radical in the body of the bull. The results of the research indicate antioxidant drug «Metisevit» in the application of its young cattle and the validity of his administration to improve the body's antioxidant status of chronic cadmium toxicosis.

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