scholarly journals RESPONS GLUKOSA DARAH BENIH IKAN JELAWAT (Leptobarbus hoeveni Blkr) DALAM MEDIA YANG DIBERI EKSTRAK DAUN UBI JALAR (Ipomoea batatas)

2020 ◽  
Vol 5 (2) ◽  
pp. 50
Author(s):  
Nur Rizki ◽  
Muhammad Sugihartono ◽  
Muarofah Ghofur
Keyword(s):  
Blood Glucose ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Leaf Extract ◽  
Potato Leaf ◽  
Glucose Response ◽  
Glucose Levels ◽  
Extract Concentration ◽  
Blood Glucose Response ◽  
Blood Glucose Levels

Use of sweet potato leaf extract to determine the blood glucose response of jelawat fish       (L. hoeveni, Blkr)  seeds maintained in the media.This study aims to determine the optimal concentration of sweet potato leaf extract to reduce the stress level of Jelawat fish (L. hoeveni, Blkr) seeds by measuring blood glucose. In this study, four treatments were used with three replications using a concentration of 2ml / L sweet potato leaf extract, 4ml / L extract concentration, 6ml / L extract concentration, and control. The results showed that the 2ml / L extract concentration was the best because it was proven that the fish blood glucose response at every 1st, 6th, 12th hour, 24th hour, 168th hour fish (L. hoeveni, Blkr)  seed blood glucose levels nettle nearly close to normal blood glucose levels in fish.

scholarly journals Assessment of Different Commercially Available Breads and Its Effect on Blood Glucose Levels of Healthy Individuals

2019 ◽  
pp. 1-5
Author(s):  
Bhavana Parmar ◽  
Rupali Sengupta
Keyword(s):  
Blood Glucose ◽  
Plasma Glucose ◽  
White Bread ◽  
Healthy Individuals ◽  
Glucose Response ◽  
High Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Response ◽  
Blood Glucose Levels ◽  
Breakfast Food

Background: Bread is one of the most commonly used breakfast food in India. The consumption also increased tremendously among children and adolescents as well as to some extent among adults. It was found that white bread raises the blood glucose levels and is not considered to be a healthy breakfast option especially for those with diabetes mellitus and those at risk of increased or borderline glucose intolerance. Aim: To assess different commercially available bread and its effect on Blood Glucose Levels of Healthy Individuals. Study Design: 5 bread varieties were chosen (namely White, Brown, Multigrain, Oats and Tutty fruity bread). The samples were fed to 30 subjects and their effect on blood glucose was analysed. Place of Study: The study was conducted in BMN College of Home Science, Matunga, Mumbai, India. Methodology: A pilot study was conducted on 30 samples to assess the Blood Glucose Levels of each type of bread. The subjects were then given bread-butter and the blood glucose response was re-tested at gap of 1 hour and 2 hour respectively. Each subject was given 5 different varieties of bread for 5 consecutive days i.e. White bread, Brown bread, Multigrain bread, Tutty Fruity bread and Oats bread. White bread is a universal standard, was used as a standard in the study.  The average plasma glucose levels were analysed in the study. Results: The average plasma glucose spike of the standard (White bread) was found to be the highest i.e (131.63 mg/dl).  It was observed that oats bread was found to have the lowest spike post 1 hour (103.43mg/dl) while tutty fruity bread exhibited a very high blood glucose response (123.90mg/dl) following the standard white bread. Conclusion: Investigations proved that oats bread should be consumed by people to mitigate metabolic syndrome due to a stressful lifestyle. Also, a healthy diet and exercise regime to be followed by subjects in the study.

Polymorphisms in the stearoyl-CoA desaturase gene modify blood glucose response to dietary oils varying in monounsaturated fatty acid content in adults with obesity

2021 ◽  
pp. 1-28
Author(s):  
David M Mutch ◽  
Dana E Lowry ◽  
Michael Roth ◽  
Jyoti Sihag ◽  
Shatha S Hammad ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Blood Glucose ◽  
Glycemic Control ◽  
Canola Oil ◽  
Glucose Response ◽  
Glucose Levels ◽  
Dietary Oils ◽  
Blood Glucose Response ◽  
Blood Glucose Levels ◽  
Stearoyl Coa Desaturase

ABSTRACT Diets varying in saturated (SFA) and monounsaturated fatty acid (MUFA) content can impact glycemic control; however, whether underlying differences in genetic make-up can influence blood glucose responses to these dietary fatty acids is unknown. We examined the impact of dietary oils varying in SFA/MUFA content on changes in blood glucose levels (primary outcome) and whether these changes were modified by variants in the stearoyl-CoA desaturase (SCD) gene (secondary outcome). Obese men and women participating in the randomized, crossover, isocaloric, controlled-feeding Canola Oil Multicenter Intervention Trial II consumed 3 dietary oils for 6 wk, with washout periods of ˜6 wk between each treatment. Diets studied included a high SFA/low MUFA Control oil (36.6% SFA/28.2% MUFA), a conventional canola oil (6.2% SFA/63.1% MUFA), and a high oleic acid canola oil (5.8% SFA/74.7% MUFA). No differences in fasting blood glucose were observed following the consumption of the dietary oils. However, when stratified by SCD genotypes, significant SNP-by-treatment interactions on blood glucose response were found with additive models for rs1502593 (p=0.01), rs3071 (p=0.02), and rs522951 (p=0.03). The interaction for rs3071 remained significant (p=0.005) when analyzed with a recessive model, where individuals carrying the CC genotype showed an increase (0.14±0.09 mmol/L) in blood glucose levels with the Control oil diet, but reductions in blood glucose with both MUFA oil diets. Individuals carrying the AA and AC genotypes experienced reductions in blood glucose in response to all 3 oils. These findings identify a potential new target for personalized nutrition approaches aimed at improving glycemic control.

PENGARUH PEMBERIAN FRAKSI ETILASETAT KULIT UBI JALAR UNGU TERHADAP KADAR MALONDIALDEHID (MDA) SERUM MENCIT PUTIH JANTAN HIPERGLIKEMIA

2018 ◽  
Vol 8 (2) ◽  
pp. 144
Author(s):  
Ria Afrianti
Keyword(s):  
Blood Glucose ◽  
Statistical Analysis ◽  
Sweet Potato ◽  
Ethyl Acetate Fraction ◽  
Serum Levels ◽  
Negative Control ◽  
Control Group ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Purple Sweet Potato

This study aims to determine the effect giving of ethylacetate fraction of leather  purple sweet potato (Ipomoea batatas (L.) Lam, on levels of malondialdehyde (MDA) serum in mice hyperglicemia were induced with streptozocin dose of 50 mg/kgBW. Mice were divided into 5 groups, each group consisting of 3 tails, group I is a negative control, group II is a positive control, group III,IV and V is given ethylacetate fraction a dose of 100 mg/kgBW, 300 mg/kgBW, and 600 mg/kgBW. Ethyl Acetate Fraction leather purple sweet potato given orally for 15 days after the animal is declared hyperglicemia and measurement of blood glucose levels on 5, 10, and 15 day after giving test preparation in animal experiments. On the 16 day throughout the mice were taken serum levels measured malondialdehid. The statistical analysis results showed that giving of ethyl acetate fraction of leather purple sweet potato at a dose of 100 mg/kgBW, 300 mg/kgBW, and 600 mg/kgBW can lower blood glucose levels in mice hyperglycemia significantly (p<0.05). Malondialdehid levels on average in each group is 1.35 nmol/ml, 3.00 nmol/ml, 2.72 nmol/ml, 2.20 nmol/ml and 2.61 nmol/ml, the results of statistical analysis showed a decrease in melondialdehid serum levels were significantly (p<0.05), where a dose of 300 mg/kgBW is an effective dose for lowering blood glucose levels followed by decreased levels of malondialdehid which give effect approaching negative control.

scholarly journals Effectiveness of Graptophyllum pictum (L.) Griff leaf extraction on blood glucose level in alloxan-induced Wistar rat

Food Research ◽  
2020 ◽  
Vol 4 (S3) ◽  
pp. 123-126
Author(s):  
A. Leonoreza ◽  
T. Excelinda ◽  
J. Elnitiarta ◽  
H.S. Heri-Nugroho ◽  
M. Hendrianingtyas ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Treatment Group ◽  
Wistar Rats ◽  
Leaf Extract ◽  
Negative Control ◽  
Normal Group ◽  
Treatment Groups ◽  
Glucose Levels ◽  
Blood Glucose Levels

Diabetes mellitus is a metabolic disease that always increasing in prevalence. Excessive glucose intake and oxidative stress that can lead to damage to the pancreatic cell or insulin resistance, are such factors that influence the occurrence of diabetes mellitus. Graptophyllum pictum (L.) Griff leaf contains active metabolites such as flavonoid which able to decrease free radical levels. This study aimed to prove the effectiveness of Graptophyllum pictum (L.) Griff leaves extract on blood glucose levels in alloxan-induced Wistar rats. In this study, twenty-five male Wistar rats were divided into five groups. On day 0, the negative control and each treatment group injected with 125 mg/kg dose of alloxan and would be checked on 4th day. On the 4th day after the rats had diabetes, normal group (K-1) was given only standard feed, Negative control (K-2) was given only alloxan intraperitoneally on day 0, first treatment group (K-3) was given 50 mg/kg dose of Graptophyllum pictum (L.) Griff, second treatment group (K-4) was given 100 mg/kg dose of the leaf extract, and the third treatment group (K-5) was given the leaf 200 mg/kg dose of the leaf extract. On the 10th day, fasting blood glucose was taken from the rats. Post-test only group design was used to be the experimental design. There were significant differences in the treatment groups (K-3, K-4, and K-5) compared to the negative control group (K-2) after treatment. The mean of blood glucose levels decreased with the increased doses of Graptophyllum pictum (L.) Griff leaf extract treatment. The treatment groups (K-3, K-4, and K-5) were not significant compared to the normal group (K-1).

scholarly journals UJI AKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK ETANOL DAUN ECENG GONDOK (Eichhornia crassipes (Mart.)Solms) DAN DAUN SINTRONG (Crassocephalum crepidioides (Benth.) S. Moore) PADA MENCIT

2021 ◽  
Vol 4 (1) ◽  
pp. 44-53
Author(s):  
Andri Priyoherianto ◽  
◽  
Panji Ratih Suci ◽  
Putri Rizki Cahya Fatimah ◽  
Atik Nur Wijayanti
Keyword(s):  
Blood Glucose ◽  
Blood Sugar ◽  
Water Hyacinth ◽  
Leaf Extract ◽  
Positive Control ◽  
Negative Control ◽  
Glucose Levels ◽  
Normal Limits ◽  
Blood Glucose Levels ◽  
Sugar Levels

Diabetes mellitus is a chronic metabolic disorder that occurs due to destruction of pancreatic ? cells characterized by blood glucose levels that exceed normal limits. The purpose of this study was to determine the therapeutic effect of the combination of water hyacinth leaf extract and Sintrong leaf in reducing blood glucose levels in alloxan-induced experimental animals. Water hyacinth leaf powder and Sintrong leaves were extracted using the maceration method with 70% ethanol as a solvent. A total of 25 mice were divided into 5 groups, namely negative control CMC-Na 0.5%, positive control glibenclamide 0.00065 mg / g BW, water hyacinth leaf extract 17.5 mg / kg BW, Sintrong leaf extract 10.5 mg/ kg BW and a combination of water hyacinth leaf extract 17.5 mg / kg BW and sintrong leaf 10.5 mg / kg BW. The results showed that a single extract of water hyacinth and Sintrong leaves was able to reduce blood sugar levels for 7 days. The combination dose was effective in reducing blood sugar levels with a combination dose of 17.5 mg/ kg water hyacinth leaf extract in combination for 7 days.

scholarly journals EVALUATION OF ANTIDIABETIC AND ANTIOXIDANT EFFECTS OF ETHANOLIC LEAF EXTRACT OF ERYTHRINA ABBYSINICA LAM, EX DC

2018 ◽  
Vol 11 (8) ◽  
pp. 300
Author(s):  
Kamadyaapa Davie Rexon ◽  
Gondwe Mavuto Masopera ◽  
Shauli Mathulo ◽  
Sewani Rusike Constance ◽  
Nkeh Chungag Benedicta
Keyword(s):  
Blood Glucose ◽  
Leaf Extract ◽  
Antioxidant Properties ◽  
Diabetic Rats ◽  
Control Group ◽  
Oral Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Ethanolic Leaf Extract ◽  
Antioxidant Effects

  Objective: This study was conducted to scientifically evaluate the antidiabetic and antioxidant effects of ethanolic leaf extract of Erythrina abbysinica (EEA).Methods: Acute and sub-chronic effects of EEA at 100, 200, and 400 mg/kg/bwt and glibenclamide (GL) at 5 mg/kg/bwt. were evaluated in both normal and streptozotocin (STZ)-induced diabetic male Wistar rats (250–300 g). The acute studies were performed using oral glucose tolerance test (OGTT). In sub-chronic studies, animals were orally administered with EEA and GL daily for 6 w. Brine shrimp assay was used to determine the toxicity of EEA. 1, 1-diphenyl-2-picrylhydrazyl, ferric reducing capacity of plasma, and thiobarbituric acid reactive substances assays were used to determine antioxidant properties of EEA.Results: Following OGTT, EEA significantly (p<0.05) and dose-dependently (100, 200, and 400 mg/kg/bwt) decreased blood glucose levels in both normal and STZ-induced diabetic rats when compared with positive and negative control counterparts at all-time points, whereas GL significantly (p<0.05) decreased blood glucose only in normal rats but not in diabetic rats. Daily, oral administration of EEA for 6 w significantly (p<0.05) and dose-dependently (100, 200, and 400 mg/kg/bwt) decreased blood glucose levels in STZ-induced diabetic rats when compared with the diabetic control group. EEA revealed weak toxicity with a lethal concentration50 value of 997 μg/ml). Furthermore, EEA showed significant free radical scavenging, total antioxidant, and anti-lipid peroxidative capacities.Conclusion: The study has shed more light on the scientific basis for the use of E. abbysinica in management of diabetes in some communities of Eastern Cape of South Africa.

scholarly journals Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Pariyarath Sangeetha Thondre ◽  
Helen Lightowler ◽  
Lis Ahlstrom ◽  
Andrew Gallagher
Keyword(s):  
Blood Glucose ◽  
Leaf Extract ◽  
Lifestyle Changes ◽  
Glycaemic Response ◽  
Double Blind ◽  
Glucose Levels ◽  
Mulberry Leaf ◽  
Blood Glucose Levels ◽  
Mulberry Leaf Extract ◽  
White Mulberry

Abstract Background There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycaemia. Significant health-related lifestyle changes are often difficult to implement and functional ingredients that can reduce glycaemic and insulaemic responses may help at risk populations. The aim of this study was to investigate whether a mulberry leaf extract could lower the glycaemic and insulinaemic responses to 75 g sucrose in healthy individuals. Methods A double-blind, randomised, placebo-controlled, crossover design trial was conducted by the Oxford Brookes Centre for Nutrition and Health. Thirty-eight participants were recruited into the trial and, after an overnight fast, were given 75 g sucrose + white mulberry leaf extract, or 75 g sucrose alone. Capillary blood samples were collected at 15-min intervals in the first hour and at 30-min intervals over the second hour to determine glucose and plasma insulin levels. Data analysis was conducted using a paired samples T test or a Wilcoxon signed rank test. Results The addition of mulberry leaf extract to sucrose resulted in a significantly lower glycaemic response and insulinaemic response compared to a matched placebo (sucrose alone). The change in blood glucose measurements were significantly lower at 15 min (p < 0.001), 30 min (p < 0.001), 45 min (p = 0.008), and 120 min (p < 0.001) and plasma insulin measurements were significantly lower at 15 min (p < 0.001), 30 min (p < 0.001), 45 min (p < 0.001), 60 min (p = 0.001) and 120 min (p < 0.001). The glucose iAUC (− 42%, p = 0.001), insulin iAUC (− 40%, p < 0.001), peak glucose (− 40.0%, p < 0.001) and peak insulin (− 41%, p < 0.001) from baseline were significantly lower for white mulberry leaf extract compared with the placebo. White mulberry leaf extract was well tolerated and there were no reported adverse events. Conclusions Mulberry leaf extract can be used as part of lifestyle changes that may lead to healthy blood glucose levels. Trial registration: ISRCTN99601810 (23 October 2020, retrospectively registered)

Effect of Aloe vera leaf extract on blood glucose levels in alloxan induced diabetic rats

2016 ◽  
Vol 6 (5) ◽  
pp. 471 ◽  
Author(s):  
Manjunath K ◽  
Bhanu G ◽  
Subash KR ◽  
Tadvi NA ◽  
Manikanta M ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Leaf Extract ◽  
Aloe Vera ◽  
Diabetic Rats ◽  
Glucose Levels ◽  
Blood Glucose Levels
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