The Correlation of Transaminase Enzymes on the Prognosis of Covid-19 Patients in the ICU Infection Center Dr. Wahidin Sudirohusodo General Hospital Makassar

Corona Virus Disease 2019 (COVID-19) is an infectious disease that has been designated as a worldwide pandemic. Symptoms of Covid-19 are not only respiratory symptoms but also extrapulmonary symptoms, including the discovery of impaired liver function in the form of increased transaminase enzymes. Therefore, this study was conducted to see the correlation of transaminase enzymes with the prognosis of COVID-19 patients treated in the Intensive Care Unit (ICU) Dr. Wahidin Sudirohusodo Hospital. The study was conducted on June to August 2021. The cross-sectional analytical research method used retrospective medical record data for the period from July to December 2020 with a sample of 137 patients with COVID-19 confirmed. From the results of the Pearson test, patients with increased SGOT were associated with a mortality prognosis (p=0.000, p<0.05) with a correlation coefficient (r) of -0.383 and an increase in SGPT were associated with a mortality prognosis (p=0.013, p<0.05) with a correlation coefficient (r) of -0.211. From the results of the Kruskal Wallis test, there were differences in prognosis in patients with increased SGOT and SGPT grades 1,2,3, and 4 (p = 0.000 and p = 0.028). There is a correlation between the increased transaminase enzymes with the prognosis of the patient's mortality. Patients with severe elevated SGOT and SGPT enzymes had a greater prognosis of mortality than those with mild enzyme elevations. Extrapulmonary symptoms of stroke were associated with increased SGOT and myocardial infarction symptoms, and nephropathy was associated with increased SGOT and SGPT. Comorbid coronary artery disease and hepatitis were associated with increased SGOT and SGPT.

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Relationship between Alcohol Consumption and Impaired Liver Function

JURNAL INFO KESEHATAN ◽

10.31965/infokes.vol18.iss2.474 ◽

2020 ◽

Vol 18 (2) ◽

pp. 163-170

Author(s):

Agustina W. Djuma ◽

Novian A. Yudhaswara ◽

Suzanne Patricia Dardeau

Keyword(s):

Alcohol Consumption ◽

Liver Function ◽

Gamma Glutamyl Transferase ◽

Research Subjects ◽

Impaired Liver Function ◽

Cross Sectional ◽

Impaired Liver ◽

Glutamyl Transferase ◽

The Impact ◽

The Relationship

East Nusa Tenggara is a province of high alcohol abuse in Indonesia. Ngada Regency has a prevalence of 38.8%. The high prevalence is inseparable from traditional factors and socio-cultural norms which strongly influence the habit of consuming alcohol, the cold temperature in this area further strengthens this habit. The impact of alcohol consumption is the emergence of various types of diseases, one of which is impaired liver function such as alcoholic liver disease. The objective of this study is to determine the relationship between alcohol consumption and impaired liver function in communities in Bajawa and Golewa Districts, Ngada Regency. This research method is an observational analytic with cross-sectional design. The research subjects were 55 people who consumed alcohol in Golewa and Bajawa Districts, who had met the inclusion criteria. Alcohol consumption was measured by the AUDIT (The Alcohol Use Disorders Identification Test) questionnaire, while the parameter for liver disorders was the level of Gamma Glutamyl Transferase (GGT). The prevalence of liver dysfunction based on GGT examination was 15%. Meanwhile, the relationship between alcohol consumption and impaired liver function was tested with the Spearman correlation with α 0.05, the correlation value was p = 0.413, which means it has a moderate or significant, not too strong relationship. It is recommended that the people of Ngada Regency reduce alcohol consumption so that it can reduce the risk of impaired liver function.

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Factors Associated with The Incidence of Infection in Tracheostomy Stoma at Mohammad Hoesin Hospital

BioScientia Medicina ◽

10.32539/bsm.v5i9.349 ◽

2021 ◽

Vol 5 (9) ◽

pp. 842-850

Author(s):

Lisa Apri Yanti ◽

Nelly Oktriyani ◽

Erial Bahar

Keyword(s):

Multivariate Analysis ◽

Tracheostomy Tube ◽

Bivariate Analysis ◽

Medical Record Data ◽

Design Data ◽

Cross Sectional ◽

Factors Associated ◽

Record Data ◽

Cross Sectional Design ◽

Significant Factors

Introduction: Tracheostomy is a surgery to open the trachea to allow air to enter the airway. Tracheostomy cannot be separated from possible complications. Tracheostomy stoma infection is one of the complications of post-tracheostomy that occurs due to the activity of several bacteria. Many factros can cause the incidence of tracheostomy stoma infection. Objective: The aim of this study is to determine the factors associated with the incidence of tracheostomy stoma infection. Methods: Observational study with cross-sectional design. Data collection was carried out using medical record data on 71 subjects who underwent tracheostomy tube replacement from july 2019 to November 2020. Results: From 71 subjects, it was found that the subjects who had tracheostomy stoma infection were 54.9%. The results of bivariate analysis showed that age (p=0.031), comorbidities (p=0.009), the type of tracheostomy tube (p=0.015), the use of antiseptic in tracheostomy dressing (p=0.020), tracheostomy tube care (p=0.013), and the interval of changing the tracheostomy tube (p=0.041) are the significant factors. The results of multivariate analysis showed that tracheostomy tube care and the interval of changing the tracheostomy tube had a significant effect on tracheostomy stoma infection. Tracheostomy tube care has a risk of 9.362 times to experience infection with CI95%(1.535-57.086) and the interval of changing the tracheostomy tube has a risk of 10.669 with CI95% (1.074-105.985). Conclusion: There is a significant relationship between age, comorbidities, type of tracheostomy tube, the use of antiseptic in tracheosotmy dressing, tracheosotmy tube care, and interval of changing the tracheostomy tube with the incidence of tracheostomy stoma infection.

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Characteristics of Pregnant Women with Premature Rupture of the Membranes at Assalam Hospital, Gemolong, Sragen

Jurnal Biometrika dan Kependudukan ◽

10.20473/jbk.v8i1.2019.93-99 ◽

2019 ◽

Vol 8 (1) ◽

pp. 93

Author(s):

Rica Frastia Prahardani ◽

Lutfi Agus Salim

Keyword(s):

Pregnant Women ◽

Secondary Data ◽

Sampling Technique ◽

Descriptive Study ◽

Premature Rupture ◽

Medical Record Data ◽

Cross Sectional ◽

Record Data ◽

Cross Sectional Design ◽

Common Infection

Gestation is the growth of an embryo which starts from conception and ends at the beginning of labor. The most common direct causes of complications in pregnancy respectively are preeclampsia (28.7%), bleeding (22.42%), and infection (3.45%). The most common infection that is experienced by mothers due to complications of pregnancy is due to premature ruptured membranes (65%). The purpose of this study was to determine the characteristics of pregnant women who experienced premature ruptured membranes at Assalam Hospital, Gemolong. This is a descriptive study with a cross-sectional design. The population is all pregnant women with premature ruptured membranes (KPD) at Assalam Hospital, Gemolong, in April–May 2015, totalling 36 women. The sample was all pregnant women with premature ruptured membranes (KPD) at Assalam Hospital, Gemolong, throughout April–May 2015 and the sampling technique used was non probability sampling. The secondary data were obtained from medical record data at Assalam Hospital, Gemolong, from April to May 2015. The results showed that the characteristics of pregnant women with KPD were that they were mostly 20–35 years of age (91.7%), had primiparous parity (63.9%), were mostly working mothers (72.2%), and had secondary education (80.6%).

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IDENTIFICATION AND ANALYSIS OF DRUG-RELATED PROBLEMS INCIDENCE AT HOSPITALIZED PATIENTS IN HAJI REGIONAL GENERAL HOSPITAL, MAKASSAR

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2021.v14i3.40391 ◽

2021 ◽

pp. 130-133

Author(s):

MUHAMMAD ALDILA SATRIA ◽

SUDIBYO SUPARDI

Keyword(s):

Length Of Stay ◽

Drug Treatment ◽

General Hospital ◽

Patient Characteristics ◽

Cross Sectional Study ◽

Bivariate Analysis ◽

Sectional Study ◽

Medical Record Data ◽

Cross Sectional ◽

Record Data

Objective: This study aims to identify inpatient medication problems and analyze the association between patient characteristics and the incidence of the drug-related problem (DRP) experienced by patients. Methods: The cross-sectional study was conducted at Haji Regional General Hospital, Makassar, using medical record data for inpatients from January to February 2020. Data were collected from September to October 2020. A total of 247 inpatients were identified using the Indonesian version of the Pharmaceutical Care Network Europe. Results: The most common DRP problem found is the effect of drug treatment not optimal (P1.2) by 35.76% and the most common cause found is no or incomplete drug treatment despite existing indication (C1.6) by 20.16%. Bivariate analysis shows that age, length of stay, and the number of drugs received are significant different with the incidence of DRP in patients (p < 0,01) respectively. Multivariate analysis using logistic regression shows that age, sex, and the number of drugs could significantly affect the incidence of DRP (p<0.05) with the r-square (R2) of 21.6%. According to this model, the largest odds ratio number and the most likely to experience DRP in a patient are age, the number of drugs, then gender (5,2; 4,6; and 2,3). Conclusion: Age, length of stay, and the number of drugs received affect the DRP incidence in a patient, while gender together with age and the number of drugs affecting the incidence of DRP in a patient.

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The Relationship between Demographic Characteristic and Quality of Life in Patients with Coronary Artery Disease

NurseLine Journal ◽

10.19184/nlj.v5i2.18514 ◽

2021 ◽

Vol 5 (2) ◽

pp. 248

Author(s):

Teguh Santoso ◽

Suhartini Suhartini ◽

Untung Sujianto ◽

Dwi Susilawati

Keyword(s):

Quality Of Life ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Correlation Coefficient ◽

Communicable Disease ◽

Demographic Characteristics ◽

Cross Sectional ◽

Artery Disease ◽

The Relationship

Background: coronary artery disease is one of non-communicable disease that leading cause of death in the global, which can disturb physical, psychological, and social aspects on the quality of life (QoL). The perception of QoL are difference among patients. The purpose of this study was to examine the relationship between demographic characteristics and quality of life in patients with coronary artery disease. Methods: This is a cross-sectional study surveyed patients with coronary artery disease. Participants were 124 (96 males and 28 females) with purposive sampling. Quality of life was measured with (SF-36) questionnaire. Spearman rho correlation coefficient were used to examine the relationships between the independent and dependent variable. Results: Spearman rho correlation coefficient analysis indicated that demographic characteristics (age, gender, marital status, and alcohol consumption) were not correlated significantly, but education level, occupation, income, and exercise were correlated significantly with quality of life. Conclusion: There were statistically significant the relationship between demographic characteristics and quality of life in patients with coronary artery disease.

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HUBUNGAN DERAJAT KEPARAHAN SIROSIS HATI DAN NILAI LAJU GLOMERULUS PADA SIROSIS HATI

e-CliniC ◽

10.35790/ecl.3.1.2015.7482 ◽

2015 ◽

Vol 3 (1) ◽

Author(s):

Pamela M. Poluan ◽

Ventje Kawengian ◽

Cerelia Sugeng

Keyword(s):

Liver Cirrhosis ◽

Medical Records ◽

Spearman Correlation ◽

Medical Record Data ◽

Cross Sectional ◽

Record Data ◽

Class B ◽

Spearman Correlation Test ◽

Cross Sectional Design ◽

Increased Activity

Abstract: Liver cirrhosis is often associated with impaired renal function. This can be due to disturbances of hemodynamic and neurohormonal systems and increased activity of the sympathetic nervous system. This will lead to a decrease in glomerular filtration rate (GFR). This study aimed to find out the connection of the liver cirrhosis degree and GFR values in liver cirrhosis subjects. This study was a cross-sectional design. Samples were 30 liver cirrhosis cases’ medical records at BLU Prof. Dr R.D Kandou Hospital Manado in the period of October 2013 to October 2014.The medical record data included age, gender, values of albumin, bilirubin, and creatinine, Child’s score, and the GFR values by using CKD-EPI formula. The corrrelation of the liver cirrhosis degrees and GFR values was tested by using the Spearman correlation test. The results showed that there was a negative, not significant correlation between class B Child’s score and GFR (r = -0.231, p = 0.618); a positive, not significant correlation between class C Child’s score and GFR (r = 0.188, p = 0.428), and btween Child’s score and GFR (r = 0.118, p = 0.533)Conclusion: There was no significant correlation between the liver cirrhosis degree (Child’s score) and GFR values.Keywords: liver cirhhosis, Child’s score, GFRAbstrak: Sirosis hati sering disertai gangguan fungsi ginjal. Hal tersebut dapat disebabkan adanya gangguan sistem hemodinamik dan neurohormonal, serta peningkatan aktivitas sistem saraf simpatis. Gangguan ini akan memicu penurunan laju filtrasi glomerulus (LFG). Penelitian ini bertujuan untuk melihat hubungan derajat keparahan sirosis hati dengan nilai laju filtrasi glomerulus pada subyek sirosis hati. Penelitian ini menggunakan desain potong lintang. Sampel peneltian ini berjumlah 30 rekam medik subyek sirosis hati yang tercatat di BLU RSUP Prof. Dr. R.D. Kandou Manado periode Oktober 2013 sampai Oktober 2014. Data rekam medik tersebut mencakup umur, jenis kelamin, nilai albumin, bilirubin, kreatinin, skor Child, dan nilai LFG menggunakan formula CKD-EPI. Hubungan derajat keparahan Child dengan LFGdiuji dengan uji korelasi Spearman. Hasil uji korelasi Spearman menunjukkan bahwa terdapat hubungan negatif dan tidak signifikan antara skor Child kelas B dengan LFG (r = -0,231, p = 0,618), hubungan positif dan tidak signifikan antara skor Child kelas Cdengan LFG (r = 0,188, p = 0,428), serta skor Child dengan LFG (r = 0,118, p = 0,533). Simpulan: Tidak terdapat hubungan signifikan antara derajat keparahan sirosis hati (Skor Child) dengan nilai LFG.Kata kunci: sirosis hati, skor Child, LFG

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INCIDENCE OF HYPERTENSION IN ASTHMA PATIENTS WHO TREATED WITH BETA-2 AGONISTS BRONCHODILATORS

International Journal of Pharmacy and Pharmaceutical Sciences ◽

10.22159/ijpps.2017v9i4.17013 ◽

2017 ◽

Vol 9 (4) ◽

pp. 181

Author(s):

Aprilita Rina Yanti Eff

Keyword(s):

Medical Record Data ◽

Cross Sectional ◽

Duration Of Therapy ◽

Record Data ◽

Asthma Patients ◽

Study Population ◽

Retrospective Study Design ◽

Beta 2 ◽

Β2 Agonist ◽

Β2 Agonists

Objective: To determine the prevalence of hypertension in hospitalized patients with asthma who were treated with beta-2 agonists. To evaluate the correlation between the duration of the use of beta-2 agonist with the incidence of hypertension.Methods: This research is a descriptive epidemiological, observational cross-sectional and retrospective study design. The study population was all adult asthma patients (age ≥ 25) without a concomitant diseases such as hypertension or metabolic syndrome treated with β2 agonists as a bronchodilator and underwent hospitalized in January 2015-December 2015 (n=108). Patient data were collected from the medical record. Data were analyzed using univariate and bivariate to count the number of occurrences of hypertension and recognizing the correlation between the duration of the use of β2 agonists with hypertension event.Results: The incidence of hypertension in patients with asthma who were treated with beta-2 agonists are 50, 93% at the stage of pre-hypertension (120 mm Hg/80 mm Hg) and 25, 9% in stage I hypertension (140 mmHg/90 mmHg). Body weight and duration of therapy with a β2 agonist positively correlated with the incidence of hypertension with a correlation coefficient (r) 0.231 and 0.386 respectively.Conclusion: In this study, duration of therapy with a β2 agonist in asthma patients positively correlated with the incidence of hypertension.

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Identification of CTX-M Gene Resistance on Bacteria Acinetobacter baumannii and Klebsiella pneumoniae in Pneumonia Patients in Haji Adam Malik Center Hospital, Medan, Indonesia

Asian Journal of Pharmaceutical Research and Development ◽

10.22270/ajprd.v8i1.640 ◽

2020 ◽

Vol 8 (1) ◽

pp. 25-28

Author(s):

Safrina S ◽

Urip Harahap ◽

Fransiscus Ginting

Keyword(s):

Klebsiella Pneumoniae ◽

Acinetobacter Baumannii ◽

M Gene ◽

Chain Reaction ◽

Medical Record Data ◽

Prospective Design ◽

Cross Sectional ◽

Record Data ◽

Center Hospital ◽

Polymerase Chain

Objectives: To find out whether Acinetobacter baumannii and Klebsiella pneumoniae that cause pneumonia have Ceftriaxon-resistant CTX-M coding genes. Interventions: The method used in this study is a cross sectional prospective design and carried out prospectively in pneumonia patients who have medical record data on the diagnosis of pneumonia patients in the period January to September 2019 at the Haji Adam Malik General Hospital in Medan by taking sputum from the patient, then detected using Polymerase Chain Reaction (PCR) in the Integrated Laboratory of the Faculty of Medicine, Universitas Sumatra Utara. Main outcomes measure: The resistance coding gene in Klebsiella pneumoniae with the percentage of CTX-M gene is 93.7% and Acinetobacter baumannii has a low percentage where the expression of CTX-M gene is 17.6%. Conclusion: The distribution of the CTX-M gene in Klebsiella Pneumoniae is higher than that of Acinetobacter baumannii.

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Charasteristics of COVID-19 Patients Treated At Santa Elisabeth Medan Hospital 2020

Sumatera Medical Journal ◽

10.32734/sumej.v4i1.5958 ◽

2021 ◽

Vol 4 (1) ◽

Author(s):

Nency Triputri ◽

Noni Novisari Soeroso

Keyword(s):

Clinical Symptoms ◽

Virus Disease ◽

Secondary Data ◽

Sampling Technique ◽

Cross Sectional Study ◽

Cross Sectional ◽

Record Data ◽

New Type ◽

Age Range ◽

First Time

Corona Virus Disease (COVID-19) is a disease caused by a new type of coronavirus (SARS-CoV-2). This virus was first discovered in Wuhan, China for the first time and has infected 90,308 people as of March 2, 2020. Infection is transmitted by large droplets or droplets within 1 - 2 m, which are generated during coughing and sneezing by symptomatic patients and people without symptoms. This infection is acquired by inhaling these droplets or touching a contaminated surface and then touching the nose, mouth and eyes. To see the characteristics of COVID-19 patients who are treated at the Santa Elisabeth Hospital Medan in 2020. Type of research is a descriptive study with a cross-sectional study design with a retrospective approach using total sampling technique. This type of research data is secondary data obtained from the medical record data of positive COVID-19 patients confirmed to be hospitalized in several Medan city hospitals in 2020.Of the 230 study samples, 147 confirmed positive COVID-19 patients were found, dominated by the age range 46-55 years. The sex most common is male. The most common clinical symptoms are respiratory disorders such as coughing, shortness of breath and fever.The number of confirmed positive patients at the hospital. Santa Elisabeth in March to October 2020 is 147 people (51.1%).

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