scholarly journals Accuracy of Platelet Count in Assessing Severity of Preeclampsia

2016 ◽  
Vol 4 (2) ◽  
pp. 21-25
Author(s):  
Nahid Reaz ◽  
Mirza Md Asaduzzaman ◽  
Shahnaj Akter Jahan ◽  
Shafeya Khanam

Background and Objectives: The present cross-sectional study was conducted to determine whether platelet count can predict the severity of preeclampsia (PE) with fair degree of accuracy. Methodology: The study was carried out at Department of Obstetrics & Gynaecology, Dhaka Medical College Hospital, Dhaka between January 2013 to December 2013 on admitted preeclamptic women. Preeclamptic women ranging between 20-35 years, gestational age between 28-40 weeks and systolic pressure 140 mmHg and/or diastolic pressure 90 mmHg with proteinuria were the study population. A total of 96 preeclamptic women meeting the enrollment criteria were included in the study. Of them 76 had severe preeclampsia and 22 had mild preeclampsia. Platelet count below 1,50000/mm3 of blood was considered low in this study. Result: Over one-quarter (27.1%) of the patients were < 20 years, 43.8% (20 - 30) years and 29.2% 30 years old with mean age of the patients being 24.9 years. Over three-quarters (77.1%) of the patients belonged to middle class and 22.9% to lower class. Majority (79.2%) of the women was at term pregnancy with ratio of primigravida and multigravida being roughly 2:3. Eight (8.3%) patients had past history of PET. Over one-third (37.5%) of the patients had systolic blood pressure 160 mmHg and 27.1% had diastolic blood pressure 110 mmHg. About 64% of the patients had anemia and 73% had severe proteinuria (albumin 3+). More than 20% of the severe preeclamptics had low (< 1,50,000 per cu-mm of blood) platelet count as opposed to 9.1% of the mild preeclamptic group. The risk of having low platelet count among severe preeclamptics was found to be more than 2-fold (95% CI = 0.5 -12.1) than their mild preeclamptic counterparts (p = 0.037). Conclusion: The study concluded that, platelet count tends to fall as severity of preeclampsia increases. However, platelet count alone cannot predict the severity of preeclampsia as majority of the severe preeclampsia bears platelet within normal range. Ibrahim Cardiac Med J 2014; 4(2): 21-25

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Rivanli Polii ◽  
Joice N.A. Engka ◽  
Ivonny M. Sapulete

Abstract: Sodium is an extracellular fluid cation which is the highest in amount, 35-40% sodium (Na) is found in the body skeleton. The function of sodium is the regulation of fluid volume, the regulation of fluid balance, the regulation of osmolarity, and the regulation of blood pressure. Blood pressure is the force that is needed to keep the blood flowing inside the blood vessel and circulates to reach all the tissues in human body. Blood pressure consists of two components, the systolic pressure and diastolic pressure. According to the study conducted by Riset Kesehatan Dasar on 2007, it was found that the Natuna Islands (coastal areas) has the highest prevalence of hypertension, which is 53,3%, while the highlands of Jayawijaya has the lowest prevalence of hypertension, which is 6,8%. The North Bolaang Mongondow regency, especially West Bolangitang district is an area which is conditioned around the coastal areas. Adolescents, according to WHO, are those aged 12-24 years old. This was an analytical descriptive research is conducted with a cross sectional study design. Afterward, the collected datas are processed using the help of SPSS software. The population is all of the students in SMAN 1 Bolangitang Barat, North Bolaang Mongondow regency and the samples were collected with purposive sampling technique. The results showed that the number of respondents who follow the research were 60 students, consisting 16 boy and 44 girl by spearman’s correlation statistical test.This study shows no correlation between the levels of sodium and blood pressure on adolescents in West Bolangitang district North Bolaang Mongondow regency. Conclusion: there is no correlation between the levels of sodium and blood pressure on adolescents in West Bolangitang district, North Bolaang Mongondow regency. Keywords: sodium, blood pressure, adolescent Abstrak: Natrium ialah kation terbanyak dalam cairan ekstrasel , 35-40% natrium (Na) ada didalam kerangka tubuh. Fungsi natrium untuk mengatur volume cairan, mengatur keseimbangan cairan, mengatur osmolaritas, dan mengatur tekanan darah. Tekanan darah adalah kekuatan yang diperlukan agar darah dapat mengalir di dalam pembuluh darah dan beredar mencapai semua jaringan tubuh manusia. Tekanan darah terdiri atas 2 bagian tekanan sistolik dan tekanan diastolik. Berdasarkan data yang dilakukan Riset Kesehatan Dasar tahun 2007 didapatakan bahwa prevalensi hipertensi tertinggi di Kepulauan Natuna (wilayah pantai) sebanyak 53,3 % sedangkan prevalensi hipertensi terendah di pegunungan jayawijaya sebanyak 6,8%. Kabupaten Bolaang mongondow utara khususnya Kecamatan Bolangitang Barat merupakan suatu wilayah yang terletak disekitaran pesisir pantai, Remaja menurut WHO adalah mereka yang berumur 12-24 tahun. Jenis penelitian ialah deskriptif analitik dengan desain potong lintang. Data diolah dengan menggunakan program SPSS. Populasi ialah semua siswa/i SMAN 1 Bolangitang Barat Kabupaten Bolaang Mongondow Utara dan sampel diambil dengan cara purposive sampling. Hasil uji korelasi Spearman menunjukkan tidak terdapat hubungan antara kadar natrium dengan tekanan darah pada remaja di Kecamatan Bolangitang Barat Kabupaten Bolaang Mongondow Utara. Simpulan: Tidak terdapat hubungan antara kadar natrium dengan tekanan darah pada remaja di Kecamatan Bolangitang Barat Kabupaten Bolaang Mongondow Utara.Kata kunci: natrium, tekanan darah, remaja


2017 ◽  
Vol 4 (4) ◽  
pp. 1218
Author(s):  
Balakrishnan Nadesan ◽  
Mani Madhavan Sachithananthamoorthi ◽  
Sivaraman Thirumalaikumarasamy ◽  
Ezhilarasu Ramalingam

Background: Hypertension is considered as a major health issue in developed as well as developing countries and its possible origin during childhood prompts pediatricians to routinely include measurement of blood pressure (BP) as an integral part of pediatric physical examination. The objectives of the study were to evaluate the normal range of blood pressure in adolescent school going students of 12-16 years, prevalence of hypertension and relationship of BP with variables like age, body mass index (BMI), socioeconomic status and family history of hypertension.Methods: A cross sectional study was undertaken for a period of one year in adolescent school children in age groups between 12-16 years. Detailed clinical examination was done in 1060 adolescent school children and BP was recorded in right upper limb and correlation of BP with BMI, family history of hypertension and diabetes were studied.Results: Mean systolic and diastolic pressure showed linear relationship with age. There was a highly statistically significant difference between mean systolic and diastolic blood pressure between lower and middle socio-economic class. Prevalence of obesity in our study was 1.13%, overweight was 7.83%. Prevalence of hypertension in obese children was 33.33% and in overweight children 18.07%. Family history of hypertension and diabetes carry a significant correlation with elevated systolic and diastolic blood pressure in adolescents.Conclusions: This study revealed that socio economic factors play a significant role in determining the blood pressure of the individual. Children of middle class have significantly elevated mean systolic pressure and mean diastolic pressure than low socio-economic groups. 


VASA ◽  
2019 ◽  
Vol 48 (3) ◽  
pp. 236-243 ◽  
Author(s):  
Theodore G. Papaioannou ◽  
Evangelos Oikonomou ◽  
George Lazaros ◽  
Evangelia Christoforatou ◽  
Georgia Vogiatzi ◽  
...  

Abstract. Background: The 2017 ACC/AHA blood pressure (BP) guidelines generated controversies due to the new proposed BP cut-off values defining hypertension. We aimed to assess aortic stiffness of subjects who are reclassified as stage 1 hypertensive according to the new guidelines and compare them with the subjects of “elevated BP” category. Patients and methods. Data from the “Corinthia” study, an observational, cross-sectional survey of 2,043 participants were analyzed. Subjects were classified into 4 groups: group A: systolic pressure (SBP) 120–129 and diastolic pressure (DBP) < 80 mmHg, group B: SBP 130–139 or DBP 80–89 mmHg, group B1: SBP 130–139 and DBP < 80 mmHg and group B2: SBP 130–139 and DBP 80–89 mmHg. Aortic stiffness was assessed by carotid-to-femoral pulse wave velocity (PWV). A value of PWV > 10m/s was consider indicative of asymptomatic organ damage while values of PWV exceeded the 90 % percentile for each age group were consider as abnormal. Results: Groups B, B1 and B2 have significantly increased PWV compared to group A, independently from age and other risk factors (PWV: 9.2 ± 2.8 vs 9.4 ± 2.7 vs 8.6 ± 2.5 vs 8.1 ± 2.3 m/s, p < 0.01, respectively). The prevalence of PWV > 10 m/s and abnormal PWV values in group A was significantly lower than the corresponding prevalence in randomly selected, age-matched subjects from group B (13.5 % vs 24.4 %, p = 0.027 and 5.6 % vs 14.2 %, p = 0.022, respectively). Conclusions: The reclassified subjects as stage 1 hypertensive by the new guidelines have a significantly increased aortic stiffness and greater prevalence in asymptomatic aortic damage compared to subjects with elevated BP. This finding may indirectly explain the increased cardiovascular risk of this group.


2018 ◽  
Vol 7 (1) ◽  
pp. 54-62
Author(s):  
Rohmah Syahitdah ◽  
Choirun Nissa

Backgrounds: Prediabetes and hypertension was being a health issue in the world. Prediabetes and hypertension that occur together will increase the risk of developing Type 2 Diabetes Mellitus (T2DM) and cardiovascular disease. Risk factor of prediabetes and hypertension who can changed is phyisical activity, stress, and nutrition intake.Objectives: This study aims to determine the association between physical activity and stress with blood pressure in prediabetes woman.Methods: The study was done at Semarang in April-June 2016. The cross-sectional study design with the 28 subjects predibetes woman aged 35-50 years selected by consecutive-sampling method. The data taken were blood presure, fat, fiber, sodium, pottasium, calsium, magneisum intake, physical activity score, and stress score. Spearman test were used to determine the association between physical activity and stress with blood pressure. Linear regression were used to multivariate analysisResults: Seventy five percent of subjects was hypertensive with mean of blood pressure was 89,25 ± 14,64 mmHg. The result showed that most subject (64,3%) were minimally active with mean 2.258,4±1.228,8 MET-minutes/week. Majority, subjects were moderate stress (56,3%). There were an association between physical activity with diastolic pressure, but not in systolic pressure. There were no association between stress with blood pressure.Conclusion: Physical activity was only associated with diastolic pressure and stress was not associated with blood pressure.


e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Queen Mandang ◽  
Adrian Umboh ◽  
Stefanus Gunawan

Abstract: Blood pressure in children varies because there are many factors that influence. One is geographic factors. Based on data from the Health Research in 2007 found that the prevalence of hypertension is highest in coastal areas while the lowest prevalence of hypertension in the coastal area. Altitude and different sodium intake on mountain and coastal areas are assumed to affect the blood pressure. This study aimed to determine the difference in blood pressure between children who live in the mountains and in the coast. We used descriptive analytic method with cross sectional design, with 107 samples according to criteria of children aged 6-12 years with no family history of obesity and hypertension. Data were obtained by using questionnaire, measurement of weight and height (BMI) and blood pressure measurement using a sphygmomanometer and cuff child. The results showed 15.5% of children with high-normal systolic pressure and 17.4% of children with high diastolic pressure in the mountains. In coastal areas, found 28% of children with normal systolic pressure-high, 13% of children of normal-high diastolic pressure, and 5% of children of high diastolic pressure. These data were analyzed using Mann Whitney test, showing the results were not statistically significantly systolic (p = 0.815) diastolic (p = 0.221) so that H0 and H1 is rejected. Conclusion: There was no difference in blood pressure among children aged 6-12 years who live in the mountains and the coast.Keywords: child's blood pressure, mountains, coastal.Abstrak: Tekanan darah pada anak bervariasi karena ada banyak faktor yang memengaruhi. Salah satunya adalah faktor geografis. Berdasarkan data Riset Kesehatan Dasar tahun 2007 didapatkan prevalensi hipertensi tertinggi di wilayah pantai sedangkan prevalensi hipertensi terendah di wilayah pantai. Ketinggian lokasi dan asupan natrium yang berbeda pada daerah pegunungan dan pesisir pantai diasumsikan berpengaruh terhadap tekanan darah. Penelitian ini bertujuan untuk mengetahui perbedaan tekanan darah antara anak yang tinggal di pegunungan dan pesisir pantai. Metode penelitian deskriptif analitik dengan rancangan potong lintang, dengan 107 sampel sesuai kriteria anak umur 6-12 tahun tanpa obesitas dan riwayat keluarga hipertensi. Data diperoleh melalui kuesioner, pengukuran berat badan dan tinggi badan (IMT) dan pengukuran tekanan darah menggunakan sphygmomanometer dan manset anak. Hasil penelitian menunjukkan 15,5% anak dengan tekanan sistolik normal-tinggi dan 17,4% anak dengan tekanan diastolik tinggi pada daerah pegunungan. Pada daerah pesisir pantai ditemukan 28% anak dengan tekanan sistolik normal-tinggi, 13% anak tekanan diastolik normal-tinggi, dan 5% anak tekanan diastolik tinggi. Data ini dianalisis menggunakan uji mann whitney, menunjukkan hasil secara statistik tidak bermakna sistolik (p=0,815) diastolik (p=0,221) sehingga H0 diterima dan H1 ditolak. Simpulan: Tidak ada perbedaan tekanan darah antara anak berumur 6-12 tahun yang tinggal di pegunungan dan pesisir pantai.Kata kunci: tekanan darah anak, pegunungan, pantai.


2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Yoel P. Abaa ◽  
Hedison Polii ◽  
Pemsi M. Wowor

Abstract: This study was aimed to obtain the profile of blood pressure and factors that could influence blood pressure of Medical Faculty students of Sam Ratulangi University of Manado year 2014. This was a descriptive study with a cross sectional design. Study population consisted of 75 students year 2014. Respondents were 48 students obtained by using simple random sampling technique. The results showed that most respondents had normal systolic pressure (41 respondents; 85.4%), normal diastolic pressure (44 respondents; 91.6%), normal body mass index (27 respondents; 56.2%), and low physical activity (43 respondents; 89.6%). Conclusion: Most students had normal systolic blood pressure, normal diastolic blood pressure, normal BMI, and low physical activity.Keywords: blood pressure, body mass index, physical activity Abstrak: Penelitian ini bertujuan untuk mengetahui gambaran tekanan darah dan faktor-faktor yang dapat memengaruhi tekanan darah mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Manado angkatan tahun 2014. Jenis penelitian ialah deskriptif dengan desain potong lintang. Populasi penelitian ialah seluruh mahasiswa angkatan 2014 Fakultas Kedokteran Universitas Sam Ratulangi yang berjumlah 75 orang. Terdapat 48 responden diperoleh dengan teknik simple random sampling. Hasil penelitian mendapatkan bahwa tekanan sistolik terbanyak ialah kategori normal (41 responden; 85,4%) dan tekanan diastolik terbanyak ialah kategori normal (44 responden; 91,6%). Indeks massa tubuh terbanyak ialah kategori normal (27 responden; 56,2%). Tingkat aktivitas fisik responden terbanyak yaitu aktifitas fisik ringan 43 orang (89,6%). Simpulan: Pada penelitian ini sebagian besar mahasiswa memiliki tekanan darah sistolik kategori normal, tekanan darah diastolik kategori normal, IMT normal, dan aktivitas fisik ringan.Kata kunci: tekanan darah, indeks massa tubuh, dan aktivitas fisik


Author(s):  
Somesh Raju ◽  
Rina Kumari ◽  
Sunita Tiwari ◽  
NS Verma

Background: Interarm systolic blood pressure difference more than 10 mm of Hg is predictor of cardiovascular and metabolic risk. Despite of sufficient physical activity there is high prevalence of obesity in police personal because of stressful working environment. No studies have addressed the significance of interarm pressure difference among them. Therefore, the present study conducted to access the relation of interarm blood pressure difference with obesity in police personnel. Aims and Objective: To estimate the interarm pressure difference in police personal to see its association with their obesity. Material and Method: This cross-sectional observational study done on 245 police workers in PAC, Sitapur, India. Subjects having more than ten years of working experience were included in study. Anthropometric measurements of subject recorded by following standard protocol. Measurement of systolic pressure in both arm recorded simultaneously by mercury sphygmomanometer. Available data analyze and expressed in percentage, mean with SD and chi square test to see the significance of association. Results: According to anthropometric results of subjects 77.14 prcent subjects were having generalised obesity and 82.04 percent of subjects having abdominal obesity. 34.29 percent of subjects showed abnormally high (?10 mmHg) inter-arm systolic blood pressure difference. Both type of obesity showed positive association with blood sugar level but no association with interarm pressure difference. Conclusion: Interarm blood pressure difference is greater in individual having obesity or prolong duration of service. Such subjects are more susceptible to develop coronary artery disease or peripheral arterial disease in future. Early screening can help to detect the vascular events likely to occur in the future Keywords: Body mass index, Waist circumference, Interarm pressure difference, Random blood sugar


Genes ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 78
Author(s):  
Vaithinathan Selvaraju ◽  
Megan Phillips ◽  
Anna Fouty ◽  
Jeganathan Ramesh Babu ◽  
Thangiah Geetha

Disparities between the races have been well documented in health and disease in the USA. Recent studies show that telomere length, a marker of aging, is associated with obesity and obesity-related diseases, such as heart disease and diabetes. The current study aimed to evaluate the connection between telomere length ratio, blood pressure, and childhood obesity. The telomere length ratio was measured in 127 children from both European American (EA) and African American (AA) children, aged 6–10 years old. AA children had a significantly high relative telomere to the single copy gene (T/S) ratio compared to EA children. There was no significant difference in the T/S ratio between normal weight (NW) and overweight/obese (OW/OB) groups of either race. Blood pressure was significantly elevated in AA children with respect to EA children. Hierarchical regression analysis adjusted for race, gender, and age expressed a significant relationship between the T/S ratio and diastolic pressure. Low T/S ratio participants showed a significant increase in systolic pressure, while a high T/S ratio group showed an increase in diastolic pressure and heart rate of AA children. In conclusion, our findings show that AA children have high T/S ratio compared to EA children. The high T/S ratio is negatively associated with diastolic pressure.


Author(s):  
Tetsuo Shoji ◽  
Hisako Fujii ◽  
Katsuhito Mori ◽  
Shinya Nakatani ◽  
Yuki Nagata ◽  
...  

Abstract Background Previous studies reported mixed results regarding the contributions of cardiovascular disease (CVD) and blood pressure to cognitive impairment in chronic kidney disease. Methods This was a cross-sectional study in 1213 patients on maintenance hemodialysis from 17 dialysis units in Japan. The main exposures were prior CVD and blood pressure components including systolic (SBP) and diastolic pressure (DBP). The outcome was low cognitive function evaluated with the Modified Mini-Mental State examination (3MS) with a cut-off level of 3MS &lt; 80. Results The median age was 67 years, median duration of dialysis was 71 months, 37% were women, 39% had diabetic kidney disease, and 36% had any pre-existing CVD. Median (interquartile range) of 3MS score was 91 (82 to 97), and 240 patients (20%) had 3MS &lt; 80. Logistic regression analysis showed that 3MS &lt; 80 was associated with the presence of any prior CVD, particularly prior stroke. 3MS &lt; 80 was associated with lower DBP but not with SBP. When patients were stratified by the presence of prior stroke, lower DBP, higher age, and lower education level were factors associated with 3MS &lt; 80 in both subgroups. In the subgroup of patients without prior stroke, diabetic kidney disease was an additional factor associated with 3MS &lt; 80. CVDs other than stroke were not associated with 3MS in either subgroup. Conclusions Prior stroke and lower DBP were associated with 3MS &lt; 80 in hemodialysis patients. These findings support the hypothesis that these vascular factors contribute to low cognitive performance in patients undergoing hemodialysis.


PEDIATRICS ◽  
1991 ◽  
Vol 87 (5) ◽  
pp. 708-711
Author(s):  
Matthew W. Gillman ◽  
Bernard Rosner ◽  
Denis A. Evans ◽  
Laurel A. Smith ◽  
James O. Taylor ◽  
...  

Previous studies of childhood blood pressure have shown tracking correlations, which estimate the magnitude of association between initial and subsequent measurements, to be lower than corresponding adult values. Inasmuch as this disparity could arise from failing to account for a larger week-to-week variability in children, blood pressure was measured for 4 successive years, on four weekly visits in each year, and with three measurements at each visit, using a random-zero sphygmomanometer, in a cohort of 333 schoolchildren aged 8 through 15 at entry. Ninety percent of subjects had measurements in 1 or more years of follow-up. For all follow-up periods (1, 2, and 3 years from baseline), the Pearson correlation coefficient (r) for both systolic and diastolic blood pressure rose substantially with the number of weekly visits used to calculate each subject's yearly blood pressure (P &lt; .0001). For systolic pressure, the 3-year r values for 1, 2, 3, and 4 visits were .45, .55, .64, and .69, respectively. For diastolic pressure (Korotkoff phase 4), the corresponding values were .28, .41, .47, and .54. These higher multiple-visit estimates of tracking approximate published adult values and raise the possibility that prediction of adult blood pressure from childhood measurements may be improved by averaging readings from multiple weekly visits.


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