scholarly journals Incidence of Pancreatic Cancer Cases in Dr. Soedarso Hospital Pontianak

2021 ◽  
Vol 15 (2) ◽  
pp. 54
Author(s):  
Dery Wahyudi ◽  
Sari Eka Pratiwi
Keyword(s):  
Pancreatic Cancer ◽  
Demographic Data ◽  
Epidemiological Studies ◽  
Incidence Rates ◽  
Strategy Development ◽  
Published Data ◽  
Preventive Strategy ◽  
West Kalimantan ◽  
Morbidity Data ◽  
And Gender

Background: Pancreatic cancer has a poor prognosis, and the symptoms are difficult to be detected early in the early stages. Indonesia Statistics on 2004–2007 states that pancreatic cancer is not included in the 10 cancers with the highest incidence. In West Kalimantan. There are no published data related to pancreatic cancer cases. This is the reason for the researchers because this data is sufficiently needed to support other studies related to pancreatic cancer.Methods: Epidemiological studies were conducted in the form of data collection at Dr. Soedarso Hospital Pontianak. Data were retrieved from cases of pancreatic cancer regression in annual Morbidity Data of Pancreatic Cancer Patients in Dr. Soedarso Hospital Pontianak from 2018 until 2009 consisting of the frequency of new cases and deaths, as well as demographic data such as age and gender of patients. Data were processed using Microsoft Excel.Results: A total of 79 cases and 9 deaths caused by pancreatic cancer were recorded in Dr. Soedarso Hospital Pontianak from January 2009 to December 2018. The highest incidence rates occurred in 2014 with 17 out of 79 cases (21.5%). As many as 63.3% of pancreatic cancer cases are dominated by men. Most cases of pancreatic cancer in patients with the age range of 45-64 years (67.1%) and the average age is 53.8 years.Conclusions: Incidence of pancreatic cancer in Dr. Soedarso Hospital Pontianak each year of 7.9 cases. Men and elderly people dominate cases of pancreatic cancer. Further study of the clinical characteristics and analysis of risk factors in patients with pancreatic cancer needs to be done to support preventive strategy development.

scholarly journals Epidemiological Trends of Rheumatoid Arthritis and PADI4, PTPN22, and HLA-DRB9 Genes Distribution in the Kazakhstan Population

2021 ◽  
Vol 9 (B) ◽  
pp. 747-757
Author(s):  
Argul Issilbayeva ◽  
Almagul Kushugulova ◽  
Assel Meiramova ◽  
Samat Kozhakhmetov ◽  
Zhanar Akhmetova ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Demographic Data ◽  
Tyrosine Phosphatase ◽  
Strong Association ◽  
Human Leukocyte ◽  
Epidemiological Studies ◽  
Incidence Rates ◽  
Nucleotide Polymorphisms ◽  
The People ◽  
The Republic

BACKGROUND: The prevalence of rheumatoid arthritis (RA) is 1% in the global population. The lack of epidemiological studies in developing countries makes it difficult to obtain a complete global epidemiological picture of RA. RA develops due to the interaction of multiple genetic and environmental factors, though the contribution of these factors to the various disease occurrence seen in different populations is unclear. AIM: The aim of our study was to analyze the dynamics of the general prevalence and incidence of RA among the population of Kazakhstan in 2017–2019 as well as to investigate the three most common single-nucleotide polymorphisms (SNP) of RA in the Kazakhstan population. METHODS: The analysis of statistical data on Form 12 “On the health of the people and the health care system” was carried out. Prevalence and incidence rates were calculated according to generally accepted rules. Demographic data for the Republic of Kazakhstan were obtained from the official website stat.gov.kz. Our study included 70 RA patients and 113 control subjects. Blood samples were collected and genotyped for peptidylarginine deiminase 4 (PADI4), protein tyrosine phosphatase 22, and human leukocyte antigen (HLA)-DRB9 SNPs by reverse transcription polymerase chain reaction. RESULTS: The prevalence of RA in Kazakhstan in 2017–2019 was 0.36–0.38%, with an incidence rate of 0.085–0.087%, which can be comparable to data of other countries in Central Asia. The allele and genotypes frequency analyses were carried out between patients and controls. The HLA-DRB9 showed significant association of the G allele odds ratio (OR) 1.96 (95% confidence interval [CI]: 1.252–3.081), p= 0.0025 and G/G genotype OR = 3.67 (95% CI: 1.58–8.54), p = 0.00162 with RA in our sample. Strong association between anti-citrullinated protein antibody (ACPA) profile and PADI4 (OR 12.19 [95% CI: 2.19–67.94], p = 0.00115) was found. CONCLUSION: There was an increase in RA prevalence with age among females and a higher crude prevalence and incidence of RA in the southern regions of Kazakhstan. HLA-DRB9 prevailed in Kazakhstani patients with RA, PADI4 showed association with ACPA-positive RA. Further studies on larger samples are required to confirm our obtained results.

scholarly journals Comorbid non-alcohol substance misuse among people with schizophrenia

2001 ◽  
Vol 179 (6) ◽  
pp. 509-513 ◽  
Author(s):  
Peter J. Duke ◽  
Christos Pantelis ◽  
Michael A. McPhillips ◽  
Thomas R. E. Barnes
Keyword(s):  
Substance Misuse ◽  
Alcohol Misuse ◽  
Demographic Data ◽  
Epidemiological Studies ◽  
Lifetime History ◽  
The Usa ◽  
History Of ◽  
And Gender ◽  
The Uk ◽  
Drug And Alcohol

BackgroundFew epidemiological studies have assessed the extent and nature of comorbid non-alcohol substance misuse in people with schizophrenia in the community in the UK.AimsTo study the extent and nature of comorbid non-alcohol substance misuse in people with schizophrenia in central London.MethodSubjects were identified in an epidemiological census survey of South Westminster. Standardised assessment of each subject included demographic data, ratings of mental state and movement disorder and questioning about drug and alcohol misuse.ResultsIndividuals with schizophrenia or related psychoses were identified (n=352) and 57 (16%) reported a lifetime history of non-alcohol substance misuse. Age and gender were the main variables relevant to the extent and pattern of misuse. Self-reported non-alcohol substance misuse showed no significant relationship with a range of outcome measures.ConclusionsThe high proportion of subjects reporting non-alcohol substance misuse is comparable with figures from the USA. The reports of lifetime misuse most commonly referred to cannabis, psychostimulants, LSD, opiates and anticholinergics. Misuse was concentrated in those younger than 36 years and was reported more often by males.

scholarly journals Demographic determinants forCampylobacterinfection in England and Wales: implications for future epidemiological studies

2008 ◽  
Vol 136 (12) ◽  
pp. 1717-1725 ◽  
Author(s):  
I. A. GILLESPIE ◽  
S. J. O'BRIEN ◽  
C. PENMAN ◽  
D. TOMPKINS ◽  
J. COWDEN ◽  
...  
Keyword(s):  
Demographic Data ◽  
Epidemiological Data ◽  
Epidemiological Studies ◽  
Population Based ◽  
Public Health Burden ◽  
Active Population ◽  
Epidemiological Tool ◽  
Significant Public Health ◽  
Gender Specific Differences ◽  
And Gender

SUMMARYDespite a significant public health burden the epidemiology of humanCampylobacterinfection remains blurred. The identification of demographic determinants forCampylobacterinfection is therefore essential for identifying potential areas for intervention. Demographic data from an active, population-based sentinel surveillance system forCampylobacterinfection (from 2000 until 2003,n=15 907) were compared with appropriate denominator data from the 2001 United Kingdom Census. Incidence was higher in males from birth until the late teens and in females from 20 to 36 years. Age- and gender-specific differences inCampylobacterincidence were observed in different ethnic and socioeconomic groups and hence are all major drivers forCampylobacterinfection. Epidemiological studies onCampylobacterinfection need to take these factors into consideration during design and analysis. The collation of detailed epidemiological data and its comparison with appropriate denominator data provides a valuable epidemiological tool for studying infection.

No Venous Thromboembolism Increase Among Transgender Female Patients Remaining on Estrogen for Gender-Affirming Surgery

2021 ◽  
Author(s):  
Aki Kozato ◽  
G W Conner Fox ◽  
Patrick C Yong ◽  
Sangyoon J Shin ◽  
Bella K Avanessian ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Demographic Data ◽  
Significant Risk ◽  
Retrospective Chart Review ◽  
Published Data ◽  
Vte Prophylaxis ◽  
Exogenous Estrogen ◽  
Increased Risk ◽  
And Gender

Abstract Background Both surgery and exogenous estrogen use are associated with increased risk of venous thromboembolism (VTE). However, it is not known whether estrogen hormone therapy (HT) exacerbates the surgery-associated risk among transgender and gender nonbinary (TGNB) individuals. The lack of published data has contributed to heterogeneity in perioperative protocols regarding estrogen HT administration for TGNB patients undergoing gender-affirming surgery. Methods A single-center retrospective chart review was performed on all TGNB patients who underwent gender-affirming surgery between November 2015 and August 2019. Surgery type, preoperative HT regimen, perioperative HT regimen, VTE prophylaxis management, outcomes, and demographic data were recorded. Results A total of 919 TGNB patients underwent 1858 surgical procedures representing 1396 unique cases, of which 407 cases were transfeminine patients undergoing primary vaginoplasty. Of the latter, 190 cases were performed with estrogen suspended for 1 week prior to surgery, and 212 cases were performed with HT continued throughout. Of all cases, 1 patient presented with VTE, from the cohort of transfeminine patients whose estrogen HT was suspended prior to surgery. No VTE events were noted among those who continued HT. Mean postoperative follow-up was 285 days. Conclusions Perioperative VTE was not a significant risk in a large, homogenously treated cohort of TGNB patients independent of whether HT was suspended or not prior to surgery.

scholarly journals Total Laparoscopic Hysterectomy: A Two-Year Experience in Apollo Hospitals Dhaka

Pulse ◽  
2016 ◽  
Vol 8 (1) ◽  
pp. 21-29
Author(s):  
Monowara Begum ◽  
Nasrin Zulfiqar ◽  
Fatema Yasmin
Keyword(s):  
Hospital Stay ◽  
Demographic Data ◽  
Operating Time ◽  
Length Of Hospital Stay ◽  
Laparoscopic Hysterectomy ◽  
Total Laparoscopic Hysterectomy ◽  
Bladder Injury ◽  
Published Data ◽  
Complication Rates ◽  
Morbidity Data

Objective: Aim of our study is to analyze the surgical outcome of total laparoscopic hysterectomy (TLH) in our patient perspective of Apollo Hospitals Dhaka.Methods: This is a retrospective, observational study where we have reviewed demographic data, intraoperative and postoperative outcomes, and morbidity data on 100 women who underwent TLH between January 2011 and December 2012.Results: Total 100 patients were studied. Among them five patient required conversion to laparotomy due to presence of severe adhesion. The major and minor complication rates were 2% (bladder injury-2 cases) and 0% respectively. The average operating time was 148 ± 40 minutes and the mean length of hospital stay was 3±1 day. The average uterine size was 10 ± 4 weeks. In our cases operating time and duration of hospital stay were very similar with lower procedural complications to other published data elsewhere.Conclusion: We have observed that TLH is a safe and acceptable alternative procedure to standard hysterectomy from the patients perspective at Apollo Hospital Dhaka.Pulse Vol.8 January-December 2015 p.21-29

Substance Use Portrayal in Oscar-nominated Movies

2020 ◽  
Vol 12 ◽  
Author(s):  
João Mauricio Castaldelli-Maia ◽  
Felipe Gil ◽  
Antonio Ventriglio ◽  
Julio Torales ◽  
Ligia Florio ◽  
...  
Keyword(s):  
Substance Use ◽  
Drug Use ◽  
Epidemiological Studies ◽  
Progressive Increase ◽  
Media Content ◽  
Media Content Analysis ◽  
Monitoring Drug ◽  
And Gender ◽  
Multiple Drugs ◽  
Gender Convergence

Background: As one of the forms of media and art most consumed in the world, Oscar-nominated movies should have their drug use representation monitored because of possibly influencing but also reflecting society’s behavior. Objective: To investigate drug use representation in scenes from movies nominated for the Academy Awards (Oscar) from 2008-2011, through media content analysis. Methods: 437 scenes from Oscar-nominated movies (best film, best actor and best actress categories) showing drug consumption and/or its effects were assessed. Each drug represented and identified in a given scene (i.e., drug use incident) was counted as a unit for the present study (n = 515). Survey settings were used to control for over- or under-estimation of the prevalence of a variable in a given year or movie. Results: All the Oscar-nominated movies portrayed at least one scene of drug use. There was a massive predominance of alcohol and tobacco in movies, with a high use among men who also use drugs, habitually or occasionally, but related to stress/tension, predominantly at home. However, there was a significant progressive increase in the use of drugs other than alcohol and tobacco, multiple drugs, and by women. Conclusion: These findings echo epidemiological studies on substance use in western countries, an overall trend towards greater home drug use representation and gender convergence since 1970, which increased since 2000. Monitoring drug use representation in Oscar-nominated movies may represent an important public health tool.

Adolescent smoking behavior and communication with parents: Depression as a mediator and gender as a moderator

2019 ◽  
Vol 47 (10) ◽  
pp. 1-9 ◽  
Author(s):  
Xieping Chen ◽  
Qian Xie ◽  
Yuting Yang
Keyword(s):  
Smoking Behavior ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Adolescent Smoking ◽  
Junior High Schools ◽  
Test Results ◽  
Negative Effect ◽  
And Gender ◽  
The Relationship ◽  
Communication Scale

Parent–adolescent communication is assumed to be an important factor affecting adolescent smoking behavior. However, the inner mechanism accounting for this association has still not been clarified in research. Our purpose in this study was to examine the relationships between parent–adolescent communication, adolescent smoking behavior, and depression, as well as gender differences in the relationship between depression and adolescent smoking behavior. Participants were 1,134 students at 6 junior high schools in China who completed the Parent-Adolescent Communication Scale, the Epidemiological Studies Depression Scale, and the Smoking Behavior Test. Results showed that parent-adolescent communication had a significant negative effect on adolescent smoking behavior and depression partially mediated the relationship between parent–adolescent communication and adolescent smoking behavior. In addition, gender moderated the relationship between depression and adolescent smoking behavior. Overall, these findings may help to promote better understanding of the relationship between parent–adolescent communication and adolescent smoking behavior.

scholarly journals Development and design of the Hantavirus registry - HantaReg - for epidemiological studies, outbreaks and clinical studies on hantavirus disease

2021 ◽  
Author(s):  
Felix C Koehler ◽  
Linda Blomberg ◽  
Thomas Theo Brehm ◽  
Stefan Büttner ◽  
Oliver A Cornely ◽  
...  
Keyword(s):  
Data Entry ◽  
Scoring Systems ◽  
Epidemiological Studies ◽  
Incidence Rates ◽  
Case Report Form ◽  
Treatment Pathways ◽  
General Data Protection Regulation ◽  
The World ◽  
Electronic Case Report Form ◽  
Substantial Risk

Abstract Background Frequent outbreaks around the globe and endemic appearance in different parts of the world emphasize the substantial risk of hantavirus diseases. Increasing incidence rates, trends of changing distribution of hantavirus species and new insights into clinical courses of hantavirus diseases call for multinational surveillance. Furthermore, evidence-based guidelines for the management of hantavirus diseases and scoring systems, which allow stratification of patients into risk categories, are lacking. Methods Hantavirus registry (HantaReg) is a novel registry platform facilitating multinational research of hantavirus-caused diseases, such as haemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). HantaReg provides an electronic case report form and uses the General Data Protection Regulation compliant platform clinicalsurveys.net, which can be accessed from any internet browser in the world. Having a modular structure, the registry platform is designed to display or hide questions and items according to the documented case (e.g. patient with HFRS versus HCPS) to facilitate fast, but standardized, data entry. Information categories documented in HantaReg are demographics, pre-existing diseases, clinical presentation, diagnostic and therapeutic approaches, as well as outcome. Conclusions HantaReg is a novel, ready-to-use platform for clinical and epidemiological studies on hantavirus diseases and facilitates the documentation of the disease course associated with hantavirus infections. HantaReg is expected to promote international collaboration and contributes to improving patient care through the analysis of diagnostic and treatment pathways for hantavirus diseases, providing evidence for robust treatment recommendations. Moreover, HantaReg enables the development of prognosis-indicating scoring systems for patients with hantavirus disease.

scholarly journals Detection of diarrhoea associated rotavirus and co-infection with diarrhoeagenic pathogens in the Littoral region of Cameroon using ELISA, RT-PCR and Luminex xTAG GPP assays

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rahinatou N. Ghapoutsa ◽  
Maurice Boda ◽  
Rashi Gautam ◽  
Valantine Ngum Ndze ◽  
Akongnwi E. Mugyia ◽  
...  
Keyword(s):  
Demographic Data ◽  
Laboratory Diagnosis ◽  
Epidemiological Studies ◽  
Sub Saharan Africa ◽  
Rt Pcr ◽  
Mortality And Morbidity ◽  
Vaccine Introduction ◽  
Littoral Region ◽  
Rotavirus Vaccines ◽  
The Impact

Abstract Background Despite the global roll-out of rotavirus vaccines (RotaTeq/Rotarix / ROTAVAC/Rotasiil), mortality and morbidity due to group A rotavirus (RVA) remains high in sub-Saharan Africa, causing 104,000 deaths and 600,000 hospitalizations yearly. In Cameroon, Rotarix™ was introduced in March 2014, but, routine laboratory diagnosis of rotavirus infection is not yet a common practice, and vaccine effectiveness studies to determine the impact of vaccine introduction have not been done. Thus, studies examining RVA prevalence post vaccine introduction are needed. The study aim was to determine RVA prevalence in severe diarrhoea cases in Littoral region, Cameroon and investigate the role of other diarrheagenic pathogens in RVA-positive cases. Methods We carried out a study among hospitalized children < 5 years of age, presenting with acute gastroenteritis in selected hospitals of the Littoral region of Cameroon, from May 2015 to April 2016. Diarrheic stool samples and socio-demographic data including immunization and breastfeeding status were collected from these participating children. Samples were screened by ELISA (ProSpecT™ Rotavirus) for detection of RVA antigen and by gel-based RT-PCR for detection of the VP6 gene. Co-infection was assessed by multiplexed molecular detection of diarrheal pathogens using the Luminex xTAG GPP assay. Results The ELISA assay detected RVA antigen in 54.6% (71/130) of specimens, with 45, positive by VP6 RT-PCR and 54, positive using Luminex xTAG GPP. Luminex GPP was able to detect all 45 VP6 RT-PCR positive samples. Co-infections were found in 63.0% (34/54) of Luminex positive RVA infections, with Shigella (35.3%; 12/34) and ETEC (29.4%; 10/34) detected frequently. Of the 71 ELISA positive RVA cases, 57.8% (41/71) were fully vaccinated, receiving two doses of Rotarix. Conclusion This study provides insight on RVA prevalence in Cameroon, which could be useful for post-vaccine epidemiological studies, highlights higher than expected RVA prevalence in vaccinated children hospitalized for diarrhoea and provides the trend of RVA co-infection with other enteric pathogens. RVA genotyping is needed to determine circulating rotavirus genotypes in Cameroon, including those causing disease in vaccinated children.

scholarly journals Animal Welfare Attitudes: Effects of Gender and Diet in University Samples from 22 Countries

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1893
Author(s):  
Christoph Randler ◽  
Ana Adan ◽  
Maria-Mihaela Antofie ◽  
Arturo Arrona-Palacios ◽  
Manecas Candido ◽  
...  
Keyword(s):  
Gender Differences ◽  
Animal Welfare ◽  
Demographic Data ◽  
Vegetarian Diet ◽  
Vegan Diet ◽  
Short Version ◽  
Convenience Sample ◽  
Gender Empowerment ◽  
Welfare Attitudes ◽  
And Gender

Animal Welfare Attitudes (AWA) are defined as human attitudes towards the welfare of animals in different dimensions and settings. Demographic factors, such as age and gender are associated with AWA. The aim of this study was to assess gender differences among university students in a large convenience sample from twenty-two nations in AWA. A total of 7914 people participated in the study (5155 women, 2711 men, 48 diverse). Participants completed a questionnaire that collected demographic data, typical diet and responses to the Composite Respect for Animals Scale Short version (CRAS-S). In addition, we used a measure of gender empowerment from the Human Development Report. The largest variance in AWA was explained by diet, followed by country and gender. In terms of diet, 6385 participants reported to be omnivores, 296 as pescatarian, 637 ate a vegetarian diet and 434 were vegans (n = 162 without answer). Diet was related with CRAS-S scores; people with a vegan diet scored higher in AWA than omnivores. Women scored significantly higher on AWA than men. Furthermore, gender differences in AWA increased as gender inequality decreased.

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