scholarly journals PLECTRANTHUS AMBOINICUS (LOUR.) SPRENG SEBAGAI BAHAN PANGAN DAN OBAT SERTA BIOAKTIVITASNYA

2018 ◽  
Vol 11 (2) ◽  
pp. 123
Author(s):  
Marina Silalahi
Keyword(s):  
Essential Oil ◽  
Literature Review ◽  
Essential Oils ◽  
Secondary Metabolite ◽  
Natural Food ◽  
Food Preservative ◽  
Anti Cancer ◽  
On Line ◽  
Plectranthus Amboinicus ◽  
Metabolite Content

ABSTRAK   Plectranthus amboinicus merupakan herba sukulen dari famili Lamiaceae yang telah lama dimanfaatkan oleh manusia sebagai bahan pangan dan obat. Pemanfaatan tumbuhan sebagai bahan pangan dan obat berhubungan dengan kandungan metabolit sekundernya. Penulisan artikel ini didasarkan pada kajian literatur dari berbagai buku dan artikel ilmiah yang diperoleh secara on line maupun off line. Daun dan batang P. amboinicus mengandung essensial oil yang menghasilkan cita rasa dan aroma yang khas digunakan sebagai sayur, bumbu masak, dan menu ibu paska melahirkan. Uji bioaktivitasnya dari ekstrak P. ambonicus memiliki aktivitas sebagai anti mikroba, anti kanker, dan hepaprotektif. Plectranthus amboinicus sangat potensial dikembangkan sebagai bahan kuliner sebagai pengawet makanan alami.   Keywords: Plectranthus amboinicus, essential oil,  antioksidan, dan antimikroba. ABSTRACT The Plectranthus amboinicus was a succulent herb belonging Lamiaceae that has long been used by humans as food and medicine. The utilization of plants as food and medicine related to secondary metabolite content. The writing of this article is based on literature review of various books and scientific articles obtained on line or off line. The leaves and stems of P. amboinicus contains essential oils that produce flavor and aroma, so that its used as a vegetable, seasoning, and maternal postpartum menu. The bioactivity of P. ambonicus extract has activity as anti microbial, anti cancer, and hepaprotective. The P. amboinicus is potentially developed as a culinary ingredient as a natural food preservative.   Keywords: Plectranthus amboinicus, essential oil, antioxidant, and antimicrobial.

scholarly journals ESSENSIAL OIL DAN PEMANFAATAN ERYNGIUM FOETIDUM L. SEBAGAI OBAT TRADISIONAL

2021 ◽  
Vol 17 (1) ◽  
pp. 14
Author(s):  
Marina Silalahi
Keyword(s):  
Abdominal Pain ◽  
Secondary Metabolites ◽  
Essential Oil ◽  
Literature Review ◽  
Essential Oils ◽  
Natural Food ◽  
Dodecanoic Acid ◽  
Food Preservative ◽  
Eryngium Foetidum ◽  
Online Sources

Eryngium foetidum (EF) is one of the Apiaceae family that is used as medicine, vegetables and cooking spices. Plants that are used as medicine are directly or indirectly related to the content of secondary metabolites. The writing of this article is based on a literature review obtained from various online sources (mainly from google schoolar and scopus) and offline (books and other research results) using EF keywords, then synthesized to explain the benefits and bioactivity of EF. In ethnobotany fever, hypertension, headache, abdominal pain, asthma, arthritis, diarrhea, and malaria. The essential oil contained in EF is dominated by (E) -2-dodecenal, dodecanoic acid, trans-2-dodecanoic acid (9.7%), (E) -2-tridecenal, duraldehyde, and tetradecanal. EF's bioactivity has been proven to be anti-microbial, antioxidant and anti-natural. The ability of EF essential oils as an anti-microbial is very potential to be developed as a natural food preservative.

scholarly journals Pemanfatan andaliman (Zanthoxylum acanthopodium DC) sebagai tanaman penghasil minyak atsiri

Kultivasi ◽  
2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Yenni Asbur ◽  
Khairunnisyah Khairunnisyah
Keyword(s):  
Essential Oil ◽  
Literature Review ◽  
Essential Oils ◽  
Research Method ◽  
Food Preservative ◽  
The Family ◽  
North Sumatra

Abstract. Andaliman (Zanthoxylum acantho-podium DC) is one of the most widely used herbs in Toba Samosir and North Tapanuli, North Sumatera, at an altitude of 1,500 m asl, found growing wild in the Tapanuli area and used as spices in traditional Batak Angkola and Batak Mandailing. Beside North Sumatra, andaliman belonging to the family Rutaceae (family of oranges) is also found in India, China, and Tibet. This study was aimed to study the role of andaliman plants as a source of essential oils. Research method used was literature review from various resources, then understand, analyze, and discussed the results. The results of literature studies shown that andaliman are widely used as cooking spices for various cuisines because the content of citrus-colored citrus oil and has a spicy flavor like pepper. In addition, the essential oil from andaliman can also be used as an antimicrobial that can be utilized as a food preservative. Keywords : Andaliman, essential oil, food preservativeTanaman andaliman (Zanthoxylum acanthopodium DC) merupakan salah satu tumbuhan rempah yang banyak terdapat di daerah Kabupaten Toba Samosir dan Tapanuli Utara, Sumatera Utara, pada daerah berketinggian 1,500 m dpl, ditemukan tumbuh liar di daerah Tapanuli dan digunakan sebagai rempah pada masakan adat Batak Angkola dan Batak Mandailing. Selain di Sumatera Utara, andaliman yang masuk dalam famili Rutaceae (keluarga jeruk-jerukan) juga terdapat di India, China, dan Tibet. Bentuknya mirip lada (merica), bulat kecil, berwarna hijau, tetapi jika sudah kering agak kehitaman. Bila buah andaliman digigit akan tercium aroma minyak atsiri yang wangi jeruk dengan rasa yang khas (getir) sehingga merangsang produksi air liur. Secara umum spesies Zanthoxylum termasuk andaliman menghasilkan alkamides menyengat yang berasal dari asam karboksilat tak jenuh ganda yang disimpan dalam pericarp (dinding buah, cangkang), tetapi tidak di dalam biji. Hasil penelitian menunjukkan kandungan minyak atsiri buah andaliman cukup tinggi, yaitu 8.01% w/w. Hal ini menunjukkan bahwa buah andaliman memiliki potensi dalam pemanfaatannya sebagai pengawet pangan alami. Kata kunci : Andaliman, minyak atsiri, pengawet pangan

Chemical variability and antioxidant activities of the essential oils of the aerial parts of Ammoides verticillata and the roots of Carthamus caeruleus and their synergistic effect in combination

2020 ◽  
Vol 23 ◽  
Author(s):  
Imane Rihab Mami ◽  
Noria Merad-Boussalah ◽  
Mohammed El Amine Dib ◽  
Boufeldja Tabti ◽  
Jean Costa ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Natural Food ◽  
Chemical Compositions ◽  
Chemical Variability ◽  
Ammoides Verticillata

Aim and Objective: Oxidative stress is implicated in the development and progression of many disease. Some of appropriate actions that could be initiated to taken to resolve the problem of these diseases are search for new antioxidant substances isolated from plants. The aims of this study were to study the intraspecies variations of A. verticillata and C. caeruleus essential oils from 8 locations using statistical analysis, the in vitro antioxidant properties of collective essential oils and in combinations. Materials and Methods: The essential oils were analyzed by GC and GC-MS. The intraspecies variations of the essential oil compositions were discussed using principal component analysis (PCA) and cluster analysis (CA). The antioxidant properties were evaluated DPPH-radical scavenging activity and β-carotene bleaching test. Results: The main components of Ammoides verticillata collective essential oil (Coll EO) were thymol (30.5%), carvacrol (23.2%), p-cymene (13.1%), limonene (12.5%) and terpinene-4-ol (12.3%). While roots of Carthamus caeruleus essential oil were dominated by carline oxide (86.2%). The chemical variability allowed the discrimination of two main Groups for both Coll EOs. A direct correlation between the altitudes, climate and the chemical compositions was evidenced. Ammoides verticulata and Carthamus caeruleus Coll Eos showed good antioxidant activity. In binary mixture, the interaction both Coll Eos and between oils rich of thymol and/or carvacrol with carlina oxide produced the best synergistic effects, compared to individual essential oils and the synthetic antioxidant (BHT). Conclusion: Ammoides verticillata and Carthamus caeruleus essential oil blends can be used as a natural food preservative and alternative to chemical antioxidants.

scholarly journals The Chemical Compositions of Essential Oils Derived from Cryptocarya alba and Laurelia sempervirens Possess Antioxidant, Antibacterial and Antitumoral Activity Potential

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5600
Author(s):  
Jorge Touma ◽  
Myriam Navarro ◽  
Betsabet Sepúlveda ◽  
Alequis Pavon ◽  
Gino Corsini ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Capacity ◽  
Diffusion Method ◽  
Natural Food ◽  
Antitumoral Activity ◽  
Chemical Compositions ◽  
Natural Medicine ◽  
Agar Disc

Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antioxidant capacity (AC) was evaluated in vitro. The cytotoxicity was determined using cell line cultures both non tumoral and tumoral. The toxicity was determined using the nematode Caenorhabditis elegans. The antimicrobial activity was evaluated against 52 bacteria using the agar disc diffusion method and the minimum inhibitory concentrations (MICs) were determined. The principal compounds found in C. alba essential oil (CA_EO) were α-terpineol (24.96%) and eucalyptol (21.63%) and were isazafrol (91.9%) in L. sempervirens essential oil (LS_EO). Both EOs showed antioxidant capacity in vitro. Both EO showed antibacterial activity against bacteria using. LS_EO showed more inhibitory effect on these cell lines respect to CA_EO. Both EOs showed toxicity against the nematode C.elegans at 3.12–50 mg/mL. The essential oils of CA and LS have an important bioactive potential in their antioxidant, antibacterial and cytotoxicity activity. Both essential oils could possibly be used in the field of natural medicine, natural food preservation, cosmetics, sanitation and plaguicides among others.

scholarly journals GC-MS fingerprints of mint essential oils

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Mirosław A. Hawrył ◽  
Krystyna Skalicka-Woźniak ◽  
Ryszard Świeboda ◽  
Małgorzata Niemiec ◽  
Klaudia Stępak ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
Essential Oils ◽  
Secondary Metabolite ◽  
Similarity Measures ◽  
Principal Component ◽  
Component Analysis ◽  
Metabolite Content

AbstractEssential oils from eleven Mentha species were obtained by Deryng hydrodistillation and analysed by GC–MS: 44 compounds were identified. The most abundant were menthone, isomenthone, menthol, carvone, piperitone oxide, D-limonene and eucalyptol. Chemometric similarity measures and principal component analysis were calculated, allowing comparisons based on secondary metabolite content. The fingerprints may be helpful in chemotaxonomy.

scholarly journals Evaluation of the phytochemical content and the use of the essential oil from the leaves of Malaysian Plectranthus amboinicus (lour) spreng as antimalarial in vivo

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Norazsida Ramli ◽  
Pakeer Oothuman ◽  
Muhammad Taher
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Plasmodium Berghei ◽  
Antimalarial Activity ◽  
Gas Chromatography Mass Spectrometry ◽  
Phytochemical Content ◽  
Major Chemical ◽  
Plectranthus Amboinicus ◽  
Total Oil

Introduction: This study was conducted to evaluate the phytochemical contents and antimalarial properties of the essential oils extracted from the leaves of Malaysian Plectranthus amboinicus in mice infected with Plasmodium berghei. Methods: The essential oils were extracted and prepared by using a steam distillation technique and subjected to phytochemical screening by using gas chromatography–mass spectrometry (GC-MS). The antimalarial activity of different extract doses of the essential oil was tested in vivo in ICR (Instritute of Cancer Research) mice infected with Plasmodium berghei (PZZ1/100) during early, established and residual infections. The control groups were treated with distilled water (containing 10% DMSO, the solvent of the test extracts) and 2 standard drugs: chloroquine and Fansidar. Results: In all, 5 compounds made up 88.34% of total oil and the major chemical compounds were carvacrol (85.14%), thymoquinone (1.65%), terpinen-4-ol (0.70%), octenol (0.62%) and thymol (0.23%). Antimalarial assay showed this essential oil as a potential prophylactic agent with the percentage chemosuppression of 45.23%, 18.28%, 45.38% and 58.26%, while treated with 50, 200, 400 and 1000 µL/kg respectively of essential oil. It also showed a potential as a curative agent with percentage of chemosuppression of 54.10%, 47.35%, 56.75% and 65.38% while treated with the above dose of essential oil. Statistically, no reduction of parasitemia was calculated for suppressive test. Conclusions: The extract has prophylactic and curative effects on P.berghei in mice.

Exploring the Potential of Aromatherapy as an Adjuvant Therapy in Cancer and its Complications: A Comprehensive Update

2021 ◽  
Vol 21 ◽  
Author(s):  
Madhuri Grover ◽  
Tapan Behl ◽  
Mohit Sanduja ◽  
Md. Habibur Rahman ◽  
Amirhossein Ahmadi
Keyword(s):  
Adjuvant Therapy ◽  
Essential Oil ◽  
Essential Oils ◽  
Chemical Constituents ◽  
Chemical Components ◽  
Traditional Practice ◽  
Mutagenic Potential ◽  
Potential Health ◽  
Anti Cancer ◽  
Authentic Data

Background: Aromatherapy is a traditional practice of employing essential oils for the therapeutic purposes, currently headed under the category of complementary and adjuvant medicine. Objective: The aim of this review article is to summarize the potential health benefits of aromatic essential oil from traditional times till the present. It also proposed some mechanisms which can be utilized as basis for using aromatherapy in cancer and cancer linked complications. Methods: To find out the relevant and authentic data, several search engines like Science direct, Pubmed, research gate, etc. were thoroughly checked by inserting key words like aromatherapy, complementary, adjuvant therapy etc. to collect the relevant material in context of article. Also, the chemical components of essential oil were classified based on the presence of functional groups, which are further explored for their cytotoxic potential. Results: The result depicted the anti-cancer potential of chemical constituents of essential oil against different types of cancer. Moreover, the essential oils show promising anti-inflammatory, anti-microbial, anti-oxidant and anti-mutagenic potential in several studies, which collectively can form the basis for initiation of its anti-cancer utility. Conclusion: Aromatherapy can serve as adjuvant economic therapy in cancer after the standardization of protocol.

Volatile Inhibitors of Phosphatidylinositol-3-Kinase (PI3K) Pathway: Anticancer Potential of Aroma Compounds of Plant Essential Oils

2018 ◽  
Vol 18 (1) ◽  
pp. 87-109 ◽  
Author(s):  
Manobjyoti Bordoloi ◽  
Surovi Saikia ◽  
Bhaskor Kolita ◽  
Rajeev Sarmah ◽  
Sonali Roy ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Essential Oil ◽  
Essential Oils ◽  
Cancer Cells ◽  
Pi3k Pathway ◽  
Lung Cancer Cells ◽  
Phosphatidylinositol 3 Kinase ◽  
Anti Cancer ◽  
A549 Lung ◽  
Phosphatidylinositol 3

Background: Cancer is a grave health problem for the world as the global cancer burden rises to 14 million new cases with 8.2 million deaths every year which is expected to rise by 70% in the next 2 decades as reported by the WHO.These steady rises in death demand for rapid developments in anti-cancer agents. Essential oils, being natural and multi-component complex systems have recently attracted a lot of attention in this search for novel anti-cancer agents. Materials and Methods: The pharmaceutical attributes of essential oil components, specifically focusing on their affinity towards COX, 5-LOX, AKT, MDM2, PDK1 and mTOR which defines the phosphatidylinositol-3- kinase (PI3K) pathway, were assessed. 123 compounds present in essential oils of different plants were analyzed for their drug like attributes which were then allowed to dock with PI3K dependent receptors crucial for the development of cancer malignancies. Among them, 21 compounds were filtered possessing high druglikeness with favourable metabolism offered by major cytochromeP450 isoforms. Finally, the best docked compounds with highest binding affinities were employed for building a ligand based pharmacophore. Being inhibitors of P-glycoproteins, these molecules also exhibited good absorption profiles and noncarcinogenic properties. Further from these 21, six compounds were evaluated against A549 lung cancer cells. Results: The pharmacophoric feature obtained can be applied for both designing and screening moieties for active inhibitors of the phosphatidylinositol-3-kinase pathway specifically from essential oil compounds and these final 21 compounds can be further promoted to studies for anti-cancer drug development. Among these, six compounds exhibited promising inhibitory results against A549 lung cancer cells. Furthermore, immunoblotting assay confirmed the efficacy of the compounds for inhibiting mTOR and AKT enzymes which are bandmasters for downstream signaling of thePI3K pathway. Conclusion: Methyl nonanoate, (R)-citronellol, cis-carveol (L-carveol), 3-methyl-Cyclohexanone, 4-carene and thujopsene were finally screened for PI3K targeted anti-cancer therapies which may find direct application as inhalers or sprays against lung cancer as these compounds are highly volatile.

scholarly journals Classification and Identification of Essential Oils from Herbs and Fruits Based on a MOS Electronic-Nose Technology

Chemosensors ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 142
Author(s):  
Mansour Rasekh ◽  
Hamed Karami ◽  
Alphus Dan Wilson ◽  
Marek Gancarz
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Electronic Nose ◽  
Sensor Array ◽  
Oxide Semiconductor ◽  
Support Vector ◽  
Natural Food ◽  
Gaseous Emissions ◽  
Edible Plant ◽  
Plant Sources

The frequent occurrence of adulterated or counterfeit plant products sold in worldwide commercial markets has created the necessity to validate the authenticity of natural plant-derived palatable products, based on product-label composition, to certify pricing values and for regulatory quality control (QC). The necessity to confirm product authenticity before marketing has required the need for rapid-sensing, electronic devices capable of quickly evaluating plant product quality by easily measurable volatile (aroma) emissions. An experimental MAU-9 electronic nose (e-nose) system, containing a sensor array with 9 metal oxide semiconductor (MOS) gas sensors, was developed with capabilities to quickly identify and classify volatile essential oils derived from fruit and herbal edible-plant sources. The e-nose instrument was tested for efficacy to discriminate between different volatile essential oils present in gaseous emissions from purified sources of these natural food products. Several chemometric data-analysis methods, including pattern recognition algorithms, principal component analysis (PCA), and support vector machine (SVM) were utilized and compared. The classification accuracy of essential oils using PCA, LDA and QDA, and SVM methods was at or near 100%. The MAU-9 e-nose effectively distinguished between different purified essential oil aromas from herbal and fruit plant sources, based on unique e-nose sensor array responses to distinct, essential-oil specific mixtures of volatile organic compounds (VOCs).

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