scholarly journals Positive Effects of Different Drug Forms of Silybin in the Treatment of Metabolic Syndrome

2015 ◽  
pp. S507-S512 ◽  
Author(s):  
M. PORUBA ◽  
Z. MATUŠKOVÁ ◽  
L. KAZDOVÁ ◽  
O. OLIYARNYK ◽  
H. MALÍNSKÁ ◽  
...  
Keyword(s):  
Total Cholesterol Level ◽  
Hdl Cholesterol ◽  
The Other ◽  
Lipid Homeostasis ◽  
Control Group ◽  
Positive Effects ◽  
Hypotriglyceridemic Effect ◽  
Dose Dependent ◽  
Positive Properties ◽  
Positive Effect

Silymarin and silybin are widely used for their hepatoprotective properties. Our previous studies confirm positive effect of silymarin on lipoprotein profile and lipid homeostasis. Advanced drug forms may improve the bioavailability of these compounds. In this study, we investigate the effects of silybin in different drug forms (standardized silybin, micronized silybin, and silybin in form of phytosomes) on dyslipidemia and glucose metabolism in hereditary hypertriglyceridemic (HHTg) rats. Male HHTg rats were divided into four groups of seven animals and were fed by experimental diets. Silybin significantly decreased serum level of triglycerides in groups of rats fed by standardized silybin and silybin in form of phytosomes compared to control group. Results show that silybin did not affect the total cholesterol level, but significantly increased the levels of HDL cholesterol in all groups of animals. Silybin in a standardized form had the highest hypotriglyceridemic effect. On the other hand, the micronized form has caused the highest increase of protective HDL and most significantly decreased glucose and insulin levels. Our results suggest that silybin is probably responsible for some positive properties of silymarin. Subsequent dose-dependent studies of silybin action may reveal the intensity of its positive effects on lipid and glucose parameters.

scholarly journals The Effect of Sea Lettuce (Ulva lactuca) Liquid Fertilizer and Zeolite Combinations on the Development of Cucumber (Cucumis sativus)

2019 ◽  
Vol 7 (7) ◽  
pp. 1021
Author(s):  
Mustafa Türkmen ◽  
Ayşe Su
Keyword(s):  
Cucumis Sativus ◽  
Organic Liquid ◽  
Germination Rate ◽  
Ulva Lactuca ◽  
The Other ◽  
Control Group ◽  
Liquid Fertilizer ◽  
Positive Effects ◽  
Fertilizer Material ◽  
Positive Effect

The combinations of organic liquid fertilizer material obtained from sea lettuce (Ulva lactuca) and different concentrations of zeolite were applied to the cucumber (Cucumis sativus) plant in six treatments with three replicates each. The combinations of the experimental groups were as follows; control group, G1 group 180 g Z (Zeolite), G2 group 90 g Z + 1140 ml Liquid Fertilizer (LF), G3 group 180 g Z + 620 ml LF, G4 group 270 g Z + 310 ml LF, G5 group 620 ml LF. Except the control group, all zeolites were applied with the first dose of liquid fertilizer, and other liquid fertilizer doses were given in three periods, after germination, flowering and yield. While the lowest germination rate was in control group, the highest rate was in group with 60 g zeolite. While the lowest seedling weight was observed in group with 90 g zeolite + 1140 ml liquid fertilizer, the highest rate was in group with 180 g zeolite + 620 ml liquid fertilizer. While the highest cucumber weight was observed in group with 270 g zeolite + 310 ml liquid fertilizer, the lowest was in group with 620 ml liquid fertilizer. Therefore, it may be said that zeolite has positive effect on germination. On the other hand, liquid fertilizer and zeolite combinations may have positive effects on the weight of the cucumber seedling and yield.

scholarly journals The Repercussion of Ai Chi on Aged People’s Balance

2014 ◽  
Vol 4 (3) ◽  
pp. 247-256
Author(s):  
Pablo Javier Olabe Sánchez ◽  
Andrés Martínez-Almagro Andreo
Keyword(s):  
Fall Prevention ◽  
Controlled Trial ◽  
Intervention Group ◽  
The Other ◽  
Control Group ◽  
Aged People ◽  
Randomized Controlled ◽  
Risk Of Fall ◽  
And Control ◽  
Positive Effect

To practice strength and balance activities are shown as useful tools to fall prevention by diverse metanalysis. On the other side, aquatic environment offers interesting properties for a therapeutic reeducation, being the Ai Chi one of its applications. Aim: To evaluate the repercussion of an Ai Chi programme on aged people’s balance. Method: A randomized controlled trial was developed comparing two groups formed by aged people with risk of fall according to the Timed Up & Go test. Intervention Group (IG) followed twelve Ai Chi sessions combined with their thermal programme; and Control Group (CG) just followed the thermal programme. Both groups spent two weeks in the Balneario of Archena (Murcia, Spain). Results: Both groups improve their balance; however, only the IG reached the non-risk of fall from the Timed Up & Go test. Conclusions: The combination of Ai Chi sessions and a thermal programme had a positive effect on aged people’s balance, showing a therapeutic and clinical relevance.

scholarly journals Weaning Holstein Calves at 17 Weeks of Age Enables Smooth Transition from Liquid to Solid Feed

Animals ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1132
Author(s):  
Sarah Schwarzkopf ◽  
Asako Kinoshita ◽  
Jeannette Kluess ◽  
Susanne Kersten ◽  
Ulrich Meyer ◽  
...  
Keyword(s):  
Metabolic Stress ◽  
Live Weight ◽  
The Other ◽  
Smooth Transition ◽  
Blood Metabolites ◽  
Positive Effects ◽  
Weaning Age ◽  
Holstein Calves ◽  
Positive Effect ◽  
Over Time

Development of calves depends on prenatal and postnatal conditions. Primiparous cows were still maturing during pregnancy, which can lead to negative intrauterine conditions and affect the calf’s metabolism. It is hypothesized that weaning calves at higher maturity has positive effects due to reduced metabolic stress. We aimed to evaluate effects of mothers’ parity and calves’ weaning age on growth performance and blood metabolites. Fifty-nine female Holstein calves (38.8 ± 5.3 kg birth weight, about 8 days old) were used in a 2 × 2 factorial experiment with factors weaning age (7 vs. 17 weeks) and parity of mother (primiparous vs. multiparous cows). Calves were randomly assigned one of these four groups. Live weight, live weight gain and morphometry increased over time and were greater in calves weaned later. Metabolic indicators except total protein were interactively affected by time and weaning age. Leptin remained low in early-weaned calves born to primiparous cows, while it increased in the other groups. The results suggest that weaning more mature calves has a positive effect on body growth, and calves born to primiparous cows particularly benefit from this weaning regimen. It also enables a smooth transition from liquid to solid feed, which might reduce the associated stress of weaning.

scholarly journals Effect of the oral administration of monosodium glutamate during pregnancy and breast-feeding in the offspring of pregnant Wistar rats

2010 ◽  
Vol 25 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Vinicius von Diemen ◽  
Manoel Roberto Maciel Trindade
Keyword(s):  
Weight Gain ◽  
Oral Administration ◽  
Wistar Rats ◽  
Monosodium Glutamate ◽  
The Other ◽  
Control Group ◽  
Pregnant Rats ◽  
Dependent Relation ◽  
Dose Dependent

PURPOSE: Determine the effects of the MSG (monosodium glutamate) in the offspring of pregnant rats through the comparison of the weight, NAL (nasal-anal length) and IL (Index of Lee) at birth and with 21 days of life. METHODS: Pregnant Wistar rats and their offspring were divided into 3 groups: GC, G10 and G20. Each of the groups received 0%, 10% and 20% of MSG, respectively from coupling until the end of the weaning period. RESULTS: Neither weight nor NAL were different among the groups at birth. The group G20 at birth had an IL lower than the group GC (p<0,05) and with 21 days of life presented weight and NAL lower than the groups G10 and this lower than the GC (p<0,01). Otherwise the G20 at 21 days of life had the IL similar to the other two groups. The weight profit percentage from birth to the 21st day of life was lower in the G20 regarding the other two groups (p<0,01). The G20 had a NAL increase percentage from birth to the 21st day of life lower than the G10 and this lower than the GC (p<0,01). CONCLUSIONS: MSG presented a dose-dependent relation in the variables weight and NAL. It caused a decrease in the growth pattern as well as in the weight gain pattern until the 21st day of life. The IL of the group 20% had an increased in relation to the control group after 3 weeks of follow up.

The influence of low-frequency laser emission on phyto- and zooplankton productivity properties

2020 ◽  
Vol 12 (2) ◽  
pp. 196-201
Author(s):  
Lidiia Khuda ◽  
Larysa Cheban ◽  
Oleksii Khudyi
Keyword(s):  
Population Density ◽  
Catalase Activity ◽  
Laser Emission ◽  
Low Frequency ◽  
Positive Influence ◽  
The Other ◽  
Control Group ◽  
Microalgae Biomass ◽  
Frequency Laser ◽  
Positive Effect

We studied the possibility of using low frequency laser emission to improve production properties of feed hydrobionts, in particular microalgae Desmodesmus armatus and Daphnia magna, which are highly applied in aquaculture. It was shown that low-frequency laser emission with the wavelength 650 nm has a positive influence on production properties of both phyto- and zooplankton. In 24 hours the biomass of irradiated D. armatus was 25% larger than non-irradiated one. Meanwhile, application λ 420 and 530 nm did not show credible accumulation of microalgae biomass. If it comes to daphnia, positive dynamic in population density enlarging was observed only since 5-7th day of cultivation, depending on emission exposition. Differences in low-frequency laser emission with λ 420 and 530 efficacy on D. magna production properties were observed while using different exposition. Thus, maximal culture density was observed when λ 420 nm for 90 s and λ 650 nm for 60 s were applied. Longer irradiation with red laser did not have positive effect. It was established that in daphnia tissues, which were influenced by λ 420 nm laser emission, TBA-active products were accumulating more. Meanwhile, for daphnias, which were irradiated with red laser, TBA amount was not different from the control group one. Catalase activity increased while applying λ 650 nm laser emission. On the other hand, λ 420 nm did not cause credible increasing of catalase activity in comparison with control group. Taking received results about photobiological effects of low-frequency laser emission on D. armatus and D. magna into consideration, both biomasses enlargement during co-cultivation can be obtained if wavelength 650 nm is used.

scholarly journals Effects of Low-Frequency Cranial Electrostimulation on the Rest-Activity Rhythm and Salivary Cortisol in Alzheimer's Disease

2003 ◽  
Vol 17 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Erik Scherder ◽  
Dirk Knol ◽  
Eus van Someren ◽  
Jan-Berend Deijen ◽  
Rob Binnekade ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Activity Rhythm ◽  
Low Frequency ◽  
Control Group ◽  
Positive Effects ◽  
Alternative Research ◽  
Positive Effect ◽  
Experimental Group ◽  
Rest Activity

Objective. In previous studies, cranial electrostimulation (CES) had positive effects on sleep in depressed patients and in patients with vascular dementia. The present study examined the effects of low-frequency CES on the rest-activity rhythm and cortisol levels of patients with probable Alzheimer's disease (AD). Method. It was hypothesised that a decreased level of cortisol would parallel a positive effect of low-frequency CES on nocturnal restlessness. Sixteen AD patients were randomly assigned to an experimental group (n = 8) or a control group (n = 8). The experimental group was treated with CES, whereas the control group received sham stimulation, for 30 minutes a day, during 6 weeks. The rest-activity rhythm was assessed by actigraphy. Cortisol was measured repeatedly in the saliva throughout the day by means of salivette tubes. Results. Low-frequency CES did not improve the rest-activity rhythm in AD patients. Moreover, both groups showed an increase instead of a decrease in the level of cortisol. Conclusions: These preliminary results suggest that low-frequency CES has no positive effect on the rest-activity rhythm in AD patients. An alternative research design with high-frequency CES in AD is discussed.

scholarly journals Reduction of the oestrogenic effect of zearalenone in pigs by a feed additive

2014 ◽  
Vol 83 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Endre Brydl ◽  
András Ványi ◽  
Róbert Glávits ◽  
László Könyves ◽  
Pál Rafai
Keyword(s):  
Fusarium Species ◽  
Live Weight ◽  
The Other ◽  
Feed Additive ◽  
Control Group ◽  
Negative Effects ◽  
Large White ◽  
Beneficial Effects ◽  
Positive Effects ◽  
Spleen And Lymph Nodes

Zearalenone is phenolic resorcyclic acid lactone produced by a number of Fusarium species grown on grains, predominantly on maize, in high moisture environment. Due to its oestrogenic effects, feeds contaminated with zearalenone can cause striking negative effects on reproduction primarily in pigs. The aim of the study was to test the efficiency of a feed additive developed for enzymatic decomposition of mycotoxins. A total of sixty 6-week-old conventional Dutch Landrace × Hungarian Large White F1 female pigs weaned at 30 ± 2 days of age were divided into 6 groups of 10 animals. Between 50 and 70 days of age, 4 groups of pigs (experimental) were treated with zearalenone (8 or 16 mg/pig dose) administered every other day via an oesophageal tube; pigs from the other two groups were not treated with zearalenone and served as controls. Throughout the experiment, the diet of two experimental groups and one control group was supplemented with a feed additive (named: Detoxa Plus) at a concentration of 1 kg/tonne; pigs from the other control group received neither zearalenone treatment, nor the feed additive. Pigs’ live weight, weight of ovaries and uterus, histological characteristics of the ovaries, uterus, vagina, spleen and lymph nodes, liver concentrations of zearalenone and its metabolites (α- and β-zearalenol) were studied. This study showed the preventive capacity of the feed additive against zearalenone. Positive effects included the prevention of uterine enlargement, beneficial effects on the histopathological scores of ovaries, uterus and vagina and reduced concentration of zearalenone and metabolites in the liver. This study demonstrates for the first time that due to its enzymatic activity Detoxa Plus renders zearalenone contaminated feeds less toxic.

Effect of feeding synbiotic products on the serum cholesterol, HDL cholesterol and non- HDL cholesterol level of albino rats

2018 ◽  
Author(s):  
Rakesh Kumar ◽  
Binita Rani ◽  
Sonia Kumari ◽  
A K Jha
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol ◽  
Total Cholesterol Level ◽  
Hdl Cholesterol ◽  
Blood Cholesterol ◽  
Control Group ◽  
Albino Rats ◽  
Therapeutic Benefits ◽  
Effect Of Feeding

Considering the excellent bio-therapeutic benefits of Lactobacillus and Bifidobacterium, this study exploited the probiotic characteristics of Lactobacillus acidophilus-015, Lactobacillus casei-297 and Bifidobacterium bifidum-229 strains with natural prebiotic substances viz. banana powder, malto-dextrin and honey to produce synbiotic food formulations and to study the effect of feeding their on the cholesterol level (mg/dl) of albino rats. On the basis of the preliminary investigation, synbiotic products with 2% banana powder, with 2% malto-dextrin, with 3% honey and synbiotic product with 2% each of, banana powder and malto-dextrin and 1% of honey were selected for the investigation of the total cholesterol, HDL-cholesterol and non-HDL cholesterol. The products showed a significant decrease in total cholesterol level, however the control group receiving the cholesterol rich laboratory diet showed a significant increase (P LESS THEN 0.01) in the total cholesterol after 45 days of feeding. There was 25.81 to 45.05% reduction of serum cholesterol was observed in case of feeding synbiotic formulations. Increase in the HDL-cholesterol and decrease in the non-HDL cholesterol were also significant. Therefore, synbiotic formulation with all these three natural prebiotic have enhanced ability to decreased down the blood cholesterol level.

scholarly journals Effect of Instructionally Embedded Formative Assessment on Students' Motivation to Learn at Higher Education Level

2020 ◽  
Vol V (I) ◽  
pp. 488-499
Author(s):  
Shumaila Hameed ◽  
Mumtaz Akhter
Keyword(s):  
Higher Education ◽  
Formative Assessment ◽  
Undergraduate Students ◽  
Education Level ◽  
Control Group ◽  
Control Group Design ◽  
Positive Effects ◽  
Post Test ◽  
Positive Effect ◽  
Experimental Group

Formative assessment is known for its positive effects it has on students' achievement. This study was designed to find out the effect of formative assessment on students' motivation at the higher education level. This study was experimental in nature; intact pre-test post-test control group design was used for data collection purpose. Sample of the study was selected conveniently, which comprised of undergraduate students. Students belonging to the experimental group were taught with instructional embedded formative assessment, whereas students belonging to the control group were taught with formal teaching methods. Students of both groups were required to fill a motivation questionnaire at the start and end of the study to check the level of intervention. Data collected through pre-test and post-test were analyzed using SPSS. The findings of the current study had suggested that instructional embedded formative assessment had a significant positive effect on students' motivation towards learning at the higher education level.

scholarly journals Effect of carissa edulis (VAHL) apocynaceae stem bark on hematological parameters in ccl¬4 induced albino rats

2021 ◽  
Vol 9 (1) ◽  
pp. 28
Author(s):  
Y. Y. Izam ◽  
B. B. Bukar
Keyword(s):  
Hematological Parameters ◽  
Stem Bark ◽  
Normal Control Group ◽  
Bark Extract ◽  
Control Group ◽  
Albino Rats ◽  
Positive Effects ◽  
Stem Bark Extract ◽  
Positive Effect ◽  
Hematological Effect

Aim/Objectives: There are claims that Carissa edulis has positive effects on hematological parameters. The present study was conducted to evaluate the safety and claimed hematological effect of Carissa edulis on rats intoxicated with carbon tetrachloride.Method: Thirty six male albino rats were randomly allotted to six groups of six rats per group. The animals were treated with (250, 500 and 1000mg/kg of the stem bark extract of Carissa edulis. The extract was administered daily by gavage to the animals for 28 consecutive days. The 50%v/v Carbon tetrachloride (CCl4) and olive oil was gavaged twice a week. The animals of the normal control group were given 5ml/kg of distilled water while those of the CCl4 group were administered CCl4 only twice a week.Result: Results of the study showed that the CCl4 group caused a significant decrease in most of the hematological parameters while the extract treated groups showed a significant increase in these parameters.Discussion / Conclusion: This suggests that the ethanolic stem bark extract has erythropoietic, thrombopoietic and positive effect on the immune system.   

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