scholarly journals Does Family History of Obesity, Cardiovascular, and Metabolic Diseases Influence Onset and Severity of Childhood Obesity?

2018 ◽  
Vol 9 ◽  
Author(s):  
Domenico Corica ◽  
Tommaso Aversa ◽  
Mariella Valenzise ◽  
Maria Francesca Messina ◽  
Angela Alibrandi ◽  
...  
2010 ◽  
Vol 13 (10) ◽  
pp. 1535-1539 ◽  
Author(s):  
Dimitrios Papandreou ◽  
Pavlos Malindretos ◽  
Israel Rousso

AbstractObjectiveObesity in children is a serious public health issue in Greece. The purpose of the current study was to identify risk factors such as birth weight, breast-feeding, dietary patterns, family history of obesity and sedentary behaviours that are possibly associated with paediatric obesity.DesignTwo hundred and five overweight and obese children (OW/OB; group 1) aged 7–15 years from eight primary and secondary schools and a control group (group 2) of normal-weight children were matched for age and sex. Overweight and obesity were calculated based on the International Obesity Taskforce criteria. Lifestyle parameters as well as anthropometric data were collected in all children. Conditional logistic regression analysis was used to identify risk factors for obesity.ResultsBreast-feeding (≥3 months) and leisure-time physical activity proved to be protector factors against obesity (OR = 0·21, 95 % CI 0·11, 0·79, P < 0·001 and OR = 0·87, 95 % CI 0·85, 0·89, P < 0·001 respectively). On the other hand, family history of obesity (OR = 3·79, 95 % CI 2·61, 4·18, P < 0·001), sugar-sweetened beverage consumption (OR = 1·77, 95 % CI 1·03, 2·76, P < 0·001) and watching television (OR = 1·99, 95 % CI 1·54, 2·76, P = 0·04) were found to be positively associated with a higher obesity risk.ConclusionsThe current findings support the literature according to which duration of breast-feeding (<3 months), a family history of obesity, watching television, sedentary lifestyle and consumption of sugar-sweetened beverages are important risk factors for childhood obesity. More studies are needed to elucidate the relationship of paediatric obesity and possible predictor factors in order to avoid health consequences in these children later on in life.


Hypertension ◽  
2000 ◽  
Vol 36 (suppl_1) ◽  
pp. 725-725
Author(s):  
Kazuko Masuo ◽  
Hiroshi Mikami ◽  
Toshio Ogihara ◽  
Michael L Tuck

P180 This study was conducted to clarify the differences in mechanisms between weight reduction (WR) sensitive and insensitive BP reduction, and to evaluate the contribution of family history of obesity (FH) to WR-induced BP reduction. In 61 obese hypertensive men (HT, 28.1±0.9 kg/m2, 35±3 years, 171±6/106±5 mmHg) and 52 obese normotensive men (NT, 27.9±0.6 kg/m2, 34±4 years, 131±5/83±4 mmHg), BMI, BP, fasting plasma norepinephrine (NE), angiotensin II (Ang II), PRA, leptin, insulin were measured every 2 week for 24 weeks with weight loss program (low caloric diet 1000kcal, 7gNaCl + excercise≥1 hr/day). WR and WR sensitive BP reduction were defined as >10% reduction in BMI or mean BP at week 12. 64% of HT and 63% of NT succeeded in WR, and 59% of HT with WR (sensitive vs insensitive P<.05) and 70% of NT with WR (P<.01) were sensitive in BP reduction. When FH+ was defined as at least one parent was obese (BMI>27.0 kg/m2), prevalence of FH+ was higher in 86% of HT and 95% of NT who failed in WR, and higher in 94% of HT and 80% of NT with WR insensitive BP reduction. Only the subjects who succeeded in WR were analyzed in this study. At entry, BP, NE, Ang II, PRA and insulin were higher in HT than in NT, although BMI and leptin were similar. However, the parameters at entry were similar between WR sensitive and insensitive BP reduction in each NT and HT. The decrements (Δ) in BP, NE, Ang II, leptin,insulin were significantly greater in subjects with WR sensitive BP reduction than subjects with WR insensitive BP reduction regardless of BP status during the study, although ΔBMI was similar. Significant decreases in the parameters were noted in earlier period in subjects with WR sensitive BP reduction than in subjects with insensitive BP reduction, and in NT than in HT. In the 4 study groups regardless of BP status or WR induced BP reduction, the decrease in NE preceded BP decline, and the decreases in Ang II, insulin, leptin & PRA followed BP decline with WR. These results suggest that a family history of obesity appears to contribute closely to resistance in weight loss and also to WR insensitive BP reduction. Suppression on sympathetic overactivity is a major mechanism in WR induced BP reduction.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Fatemeh Ranjbar ◽  
Alireza Ghanepour ◽  
Homayoun Sadeghi-Bazargani ◽  
Mahbob Asadlo ◽  
Amineh Alizadeh

Induced weight gain is a disturbing side effect of Olanzapine that affects the quality of life in psychotic patients. The aim of this study was to assess the efficacy of Ranitidine in attenuating or preventing Olanzapine-induced weight gain. A parallel 2-arm clinical trial was done on 52 patients with schizophrenia, schizoaffective and schizophreniform disorders who received Olanzapine for the first time. All these were first-episode admitted patients. They were randomly allocated to receive either Ranitidine or placebo. The trend of body mass index (BMI) was compared between groups over 16-week course of treatment. Mean weight was 62.3 (SD: 9.6) kg at baseline. Thirty-three subjects (63.5%) had positive family history of obesity. The average BMI increment was 1.1 for Ranitidine group and 2.4 for the placebo group. The multivariate analysis showed this effect to be independent of sex, family history of obesity, and baseline BMI value. The longitudinal modeling after controlling for baseline values failed to show the whole trend slope to be different. Although the slight change in trend’s slope puts forward a hypothesis that combined use of Ranitidine and Olanzapine may attenuate the weight gain long run, this needs to be retested in future larger scale long-term studies. This trial is registered with IRCT.ir201009112181N5.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
H Al-Saadi ◽  
A. Al Kamzari ◽  
H Malallah ◽  
N AlSheala ◽  
J Al-Saadi ◽  
...  

Abstract Background Childhood obesity is a public health concern that in expanding globally. Of those aged between 5-19 years in Oman, 32% were found to be overweight in 2016. Method An electronic survey was distributed to in-training and post residency paediatricians in Oman. Results A total of 69 responses met the inclusion criteria and were analysed. 50% of participants were less than 30 years-old (53.6% female). 70% were in training residency (R1, R2 24.6%, R3, R4 36.2%,) and 30% were post residency. 72% had their training in Oman. About half of participants measure child’s weight and Height, however, only 24.4% document BMI and compare with previous records. 75% regularly obtain family history of obesity and related conditions along with dietary intake. More than half of participants were not confident on discussing weight and related complication with the child, but 62.3 % were confident in discussing it with the parents. 50% were confident in initiating treatment for childhood obesity and providing dietary advice. Attitudes towards exposure to childhood obesity and management varied and overall excellent exposure accounted for less than one third of responses (Medical school 21.7%, Residency 26.1%, 27.5%). In general, only 20.6% believe they are confident in managing childhood obesity and only 29% attended seminar or training on childhood obesity. 93% believe there is a need for a more focused training on childhood obesity prevention and management. Conclusions Great efforts need to be targeted towards strengthening Paediatricians’ confidence in childhood obesity prevention and management via in residency-training and continuous professional development.


BioMedica ◽  
2021 ◽  
Vol 37 (2) ◽  
pp. 93-99
Author(s):  
Mehnaz Munir ◽  
Hamza Nadeem Malik ◽  
Muhammad Jareer Alam ◽  
Ammara Arif ◽  
Fiza Khalid

<p><strong>Background and Objective:</strong> Obesity leads to multiple complications that in turn increase mortality worldwide. There is a rapid rise in obesity in the last decade, especially among physicians. The objective of this study was to find out the frequency and relationship of obesity with socio-economic factors among faculty of a local medical college in Lahore, Pakistan.<br /><strong>Methods: </strong>A descriptive cross-sectional study was conducted on 162 medical and paramedical staff of Fatima Memorial College of Medicine and Dentistry, Lahore for a duration of 7 months from February 2019 to August 2019. Data were collected by filling the questionnaires and standard tools were used for height and weight measurement. Overweight/obesity was defined as a body mass index of &ge;25 kg/m2.<br /><strong>Results:</strong> In this study, out of 86 males and 76 females, the majority of the respondents were between the ages of 21 and 35 years. Seventy three (45.1%) and thirty (18.5%) respondents were overweight and obese, respectively. Out of a total 162 subjects, 38 (24%) were hypertensive and 18 (11%) were suffering from diabetes. There was a statistically significant association of obesity with age (p &lt; 0.05), marital status (p &lt; 0.001), family history of obesity (p &lt; 0.001), and smoking (p &lt; 0.05).<br /><strong>Conclusion: </strong>Risk factors like age, marital status, family history of obesity, and smoking have a strong correlation with obesity in faculty members of a medical school.</p>


2020 ◽  
Author(s):  
Marzieh Alamolhoda ◽  
Seyyed Taghi Heydari ◽  
Seyyed Mohammad Taghi Ayatollahi ◽  
Reza Tabrizi ◽  
Maryam Akbari ◽  
...  

Abstract Background: The present study was conducted to jointly assess some specific factors related to body fat measures using a multivariate multilevel analysis in a representative sample of Iranian mid-adolescents. Methods: This study was conducted among 2538 students (1286 boys) aged 14 - 20 years old, who were randomly selected among 16 public high schools by multi-stage random sampling procedure from all education districts of Shiraz, Iran. Data on demographic characteristics, family history of obesity, physical activity, socio-economic (SES) variables and screen time were collected. Height, weight, triceps (TST), abdominal (AST), and subscapular (SST) skinfold thickness were measured and their body mass index (BMI) was calculated. A multivariate multilevel approach was used to analyze the factors associated with obesity measures of the TST, AST, SST at the child and district levels. Results: In this study, the prevalence of overweight and obesity was estimated to be 10.2 and 5.1%, respectively. Overall, the major portion of the total variance in TST (97.1%), AST (97.7%), and SST (97.5%) was found at the child level. The results of multivariate multilevel method revealed that being girls, having a family history of obesity, and SES were significantly associated with increasing of three body fat measures (all the p-values were less than 0.05). There were significant positive associations between moderate to vigorous physical activities with AST and SST (for AST: β =2.54, SE=1.40, p=0.05; for SST: β =2.24, SE=1.20, p=0.05). Compared to children in 14-16 age group, children in age group 16-18 years had less TST (β =-0.67, SE=0.34, p=0.04). Furthermore, other age groups and screen time did not play an important role in three outcome variables. Conclusions: The results showed some factors that contribute to three body fat measures. Therefore, it is necessary to develop effective interventions to prevent the effects of individual and environmental undesirable factors on childhood obesity in both family and community levels.


2020 ◽  
Vol 2 (1) ◽  
pp. 39
Author(s):  
Dwi Agustina

Diabetes Mellitus is one of the chronic illness. DM is metabolic diseases with characteristic hyperglycemia that occur di to abnormal insulin secretion, insulin performance or both (ADA, 2010). Depend on PERKENI (2011), complication of DM occur from uncontrolled blood glucose level, such as neuropathy, hypertension, coronary heart disease, retinopathy, nephropathy and gangrene. The people who have high risk of DM are high-carbohydrate diets, have a family history of diabetes Mellitus. there for we need to early detection to be prevention became Diabetes Mellitus disease. Early detection of activities of patients with DM are held at RW 07 due to DM risk faktor that occur in that area. Community Service Activities were carried out on Wednesday, March 23, 2016 at the RW 07 Pekayon village meeting hall. Activities include measuring glucose level and counseling. For the results of early detection blood glucose level, it was found that 56 out of 82 residents experienced and increase in blood glucose level (68%). Most of them carry out consultations related to diet and Diabetes Mellitus family history


2021 ◽  
Vol 14 (6) ◽  
pp. e242227
Author(s):  
Catarina Cordeiro ◽  
Paula Garcia ◽  
Dalila Coelho ◽  
Mónica Oliva

Congenital cataract can be caused by several systemic diseases and differential diagnosis should be done between infections, genetic or metabolic diseases. We present a case of a 12-month-old girl with bilateral nuclear cataracts that was referred for investigation. Since she did not present a family history of congenital cataracts or metabolic diseases, and her physical examination was normal, a systemic evaluation was performed. Biochemical studies disclosed abnormal galactose metabolism signs. The diagnosis of galactokinase (GALK1) deficiency was considered and the study of the GALK1 gene allowed identifying a pathogenic genetic variant and a predictably pathogenic missense mutation, previously not described. Dietary measures were imposed with a good evolution.


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