scholarly journals Therapeutic Potentials of Antiviral Plants Used in Traditional African Medicine With COVID-19 in Focus: A Nigerian Perspective

2021 ◽  
Vol 12 ◽  
Author(s):  
Alfred Francis Attah ◽  
Adeshola Adebayo Fagbemi ◽  
Olujide Olubiyi ◽  
Hannah Dada-Adegbola ◽  
Akinseinde Oluwadotun ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Negative Impact ◽  
Herbal Remedy ◽  
Antiviral Drug ◽  
Specific Treatment ◽  
Sub Saharan Africa ◽  
In Vitro Assays ◽  
Global Public Health ◽  
Health Crisis ◽  
The Impact

The coronavirus disease 2019 (COVID-19) pandemic is caused by an infectious novel strain of coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which was earlier referred to as 2019-nCoV. The respiratory disease is the most consequential global public health crisis of the 21st century whose level of negative impact increasingly experienced globally has not been recorded since World War II. Up till now, there has been no specific globally authorized antiviral drug, vaccines, supplement or herbal remedy available for the treatment of this lethal disease except preventive measures, supportive care and non-specific treatment options adopted in different countries via divergent approaches to halt the pandemic. However, many of these interventions have been documented to show some level of success particularly the Traditional Chinese Medicine while there is paucity of well reported studies on the impact of the widely embraced Traditional African Medicines (TAM) adopted so far for the prevention, management and treatment of COVID-19. We carried out a detailed review of publicly available data, information and claims on the potentials of indigenous plants used in Sub-Saharan Africa as antiviral remedies with potentials for the prevention and management of COVID-19. In this review, we have provided a holistic report on evidence-based antiviral and promising anti-SARS-CoV-2 properties of African medicinal plants based on in silico evidence, in vitro assays and in vivo experiments alongside the available data on their mechanistic pharmacology. In addition, we have unveiled knowledge gaps, provided an update on the effort of African Scientific community toward demystifying the dreadful SARS-CoV-2 micro-enemy of man and have documented popular anti-COVID-19 herbal claims emanating from the continent for the management of COVID-19 while the risk potentials of herb-drug interaction of antiviral phytomedicines when used in combination with orthodox drugs have also been highlighted. This review exercise may lend enough credence to the potential value of African medicinal plants as possible leads in anti-COVID-19 drug discovery through research and development.

A Review Article on the Therapeutic Potential of Medicinal Plants for Prevention and Treatment of secondary infection in patients with COVID-19

2021 ◽  
Vol 08 ◽  
Author(s):  
Swati Rathore ◽  
Richa Tripathy Tiwari ◽  
Neha Rai ◽  
Debarshi Kar Mahapatra ◽  
Shailendra Patil ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Secondary Infection ◽  
Antiviral Drug ◽  
Specific Treatment ◽  
International Health ◽  
Review Article ◽  
Health Crisis ◽  
Treatment And Prevention ◽  
Herbal Formulations

: COVID-19 is an infectious disease, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) that is rapidly spreading all over the world and responsible for the international health crisis. In an earlier period, various synthetic antiviral drugs and clinical therapies have been used to control the viral infection but at present, there is no specific treatment available for COVID-19 infection. Several approaches like ritonavir, lopinavir, hydroxychloroquine, and chloroquine have been proposed. India is a hub of medicinal plants, so there is a chance to find out the way to combat the COVID-19 pandemic. The medicinal herbal formulations may enhance the immunity and come up with a powerful antiviral drug, which is an urgent need to control the outbreak of coronavirus. In this review article, we have discussed epidemiology, clinical outcomes, treatment, and prevention of this novel epidemic coronavirus from medicinal herbal formulations perspective. We have also emphasized the reported antiviral activity and immunity-boosting property of the Indian medicinal plants. This article also suggests that the drug or formulation obtained from medicinal plant sources may have low fatal outcomes, quick response, and safe in the management and prevention of this pandemic outbreak.

scholarly journals COVID-19 as an “Infodemic” in Public Health: Critical Role of the Social Media

2021 ◽  
Vol 9 ◽  
Author(s):  
Debanjan Banerjee ◽  
K. S. Meena
Keyword(s):  
Public Health ◽  
Social Media ◽  
Critical Role ◽  
Global Public Health ◽  
Sources Of Information ◽  
Multiple Sources ◽  
Health Crisis ◽  
Digital Platforms ◽  
The Impact

The Coronavirus disease 2019 (COVID-19) pandemic has emerged as a significant and global public health crisis. Besides the rising number of cases and fatalities, the outbreak has also affected economies, employment and policies alike. As billions are being isolated at their homes to contain the infection, the uncertainty gives rise to mass hysteria and panic. Amidst this, there has been a hidden epidemic of “information” that makes COVID-19 stand out as a “digital infodemic” from the earlier outbreaks. Repeated and detailed content about the virus, geographical statistics, and multiple sources of information can all lead to chronic stress and confusion at times of crisis. Added to this is the plethora of misinformation, rumor and conspiracy theories circulating every day. With increased digitalization, media penetration has increased with a more significant number of people aiding in the “information pollution.” In this article, we glance at the unique evolution of COVID-19 as an “infodemic” in the hands of social media and the impact it had on its spread and public reaction. We then look at the ways forward in which the role of social media (as well as other digital platforms) can be integrated into social and public health, for a better symbiosis, “digital balance” and pandemic preparedness for the ongoing crisis and the future.

scholarly journals CONSTRUCTION BUDGET AND ITS IMPACT ON CONSTRUCTION COSTS IN TIMES OF SANITARY CRISIS IN CORPORACION SANTA MARIA

2021 ◽  
Vol 9 (07) ◽  
pp. 112-118
Author(s):  
Dra. Flor Calvanapon Alva ◽  
◽  
Mg. Karina Cardenas Rodriguez ◽  
Silvia Cespedes Esquivel ◽  
Roxana Lujan Rodriguez ◽  
...  
Keyword(s):  
San Francisco ◽  
Negative Impact ◽  
Profit Margin ◽  
School Buildings ◽  
Construction Costs ◽  
Health Crisis ◽  
Documentary Analysis ◽  
Record Card ◽  
The Impact ◽  
Santa Maria

In order to determine the impact of the construction budget on the construction costs of the Santa Maria Corporation SAC-2020, an applied research was carried out, qualitative approach, non-experimental design and correlational scope, the sample are works executed in times of health crisis the school buildings No. 81540 San Francisco de Asis and No. 80638 Americo Aguilar Celis, in the province of Viru. Thestudytechniqueused was documentary analysis and the instrument was a record card. The data obtained were processed to evaluate the incidence of the variables by means of statistical tables where it was found that 4.29% additional materials were used for the first work and 4.33% additional for the second, with respect to the budget in the case of direct general expenses, 18.75% and 23.33% respectively, additional to the estimate. It is concluded that the construction budget has a negative impact on the construction costs of Corporacion Santa Maria SAC-2020 in times of sanitary crisis, observing relevant variations between the estimated and executed costs, not obtaining the expected profit margin noting that in the case of the first project the profit margin is only 10% of the estimate and in the second projectitis 0%.

scholarly journals Impact of COVID-19 on the trade of goods and services in Spain

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Asier Minondo
Keyword(s):  
Negative Impact ◽  
The European Union ◽  
Firm Level ◽  
Health Crisis ◽  
Content Type ◽  
Goods And Services ◽  
Containment Measures ◽  
Trade Of Services ◽  
The Impact

Purpose This paper aims to analyze the impact of COVID-19 on the trade of goods and services in Spain. Design/methodology/approach This paper uses monthly trade data at the product, region and firm level. Findings The COVID-19 crisis has led to the sharpest collapse in the Spanish trade of goods and services in recent decades. The containment measures adopted to arrest the spread of the virus have caused an especially intense fall of trade in services. The large share of transport equipment, capital goods, products that are consumed outdoors (i.e., outdoor goods) and tourism in Spanish exports has made the COVID-19 trade crisis more intense in Spain than in the rest of the European Union. Practical implications The nature of the collapse suggests that trade in goods can recover swiftly when the health crisis ends. However, COVID-19 may have a long-term negative impact on the trade of services that rely on the movement of people. Originality/value It contributes to understand how COVID-19 has affected the trade in goods and services in Spain.

scholarly journals Exit Strategies for COVID 19: An ISM and MICMAC approach

2020 ◽  
Vol 15 (3) ◽  
pp. 94-109 ◽  
Author(s):  
Debashree Das ◽  
Avik Datta ◽  
Patanjal Kumar
Keyword(s):  
World War Ii ◽  
Environmental Sustainability ◽  
Disease Surveillance ◽  
Specific Treatment ◽  
Well Being ◽  
Health Crisis ◽  
Exit Strategies ◽  
State And Local ◽  
The Government ◽  
The Impact

COVID 19 pandemic is the worst crisis that mankind has seen since World War-II. It has exposed glaring loopholes in the healthcare system and led to a global health crisis. In absence of any specific treatment or vaccine, countries began to enforce strict lockdown measures leading to a complete shutdown of economic activities. The purpose of this study is to identify key exit strategies that can be implemented to mitigate the impacts of COVID 19. Identification and categorisation of parameters have been done using multi criterion decision making tool of Interpretive Structural Modelling (ISM) and MICMAC analysis. The study highlights a classification of key strategies based on their driving power and dependence which may enable Government to strengthen the disease surveillance system and effectively reduce the impact of the disease. The findings of the study suggest that Environmental Sustainability and Human Well-being; Online Awareness and Capacity Building Programme; Graded Surveillance- Targeted Restrictions and Stricter norms for Inter-State Mobility; and Harmonization between Centre, State and Local Authorities are the most important strategies that needs to be factored in while planning for the post lockdown economic recovery. Thus, the study can assist the government in devising exit strategies while framing the pandemic response plan.

Developing Medicines in Line with Global Public Health Needs: The Role of the World Health Organization

2011 ◽  
Vol 20 (2) ◽  
pp. 290-297 ◽  
Author(s):  
TIKKI PANG
Keyword(s):  
World Health Organization ◽  
Gender Violence ◽  
Sub Saharan Africa ◽  
World Health ◽  
Director General ◽  
Global Public Health ◽  
Absolute Poverty ◽  
The World ◽  
Health Organization ◽  
The Impact

“I want my leadership to be judged by the impact of our work on the health of two populations: women and the people of Africa.” This is how Dr. Margaret Chan, the current Director-General of the World Health Organization (WHO), described her leadership mission. The reason behind this mission is evident. Women and girls constitute 70% of the world’s poor and 80% of the world’s refugees. Gender violence against women aged 15–44 is responsible for more deaths and disability than cancer, malaria, traffic accidents, and war. An estimated 350,000 to 500,000 women still die in childbirth every year. The negative health implications of absolute poverty are worst in Sub-Saharan Africa and South Asia. Hence, Chan aims to have the biggest impact on the world’s poorest people.

Financial Inclusion and Gender Inequality Reduction: Evidence from Sub-Saharan Africa

2019 ◽  
Vol 67 (3-4) ◽  
pp. 367-372
Author(s):  
Sylvester Ohiomu ◽  
Evelyn Nwamaka Ogbeide-Osaretin
Keyword(s):  
Gender Inequality ◽  
Financial Services ◽  
Negative Impact ◽  
Estimation Method ◽  
Financial Inclusion ◽  
Sub Saharan Africa ◽  
Sub Saharan ◽  
The Government ◽  
And Gender ◽  
The Impact

Reduced inequality and gender equality are parts of the sustainable development goals (SDGs) towards global development, but the financial sector appears daunted in respect of financial inclusion for these noble goals. Concerns are more on gender inequality in the area of full utilisation of financial and human resources. Hence, this study investigated the impact of financial inclusion on gender inequality in sub-Saharan Africa. The study employed the generalised method of moments (GMM) estimation method on panel data on some countries in sub-Saharan Africa. The result of the study revealed that financial inclusion substantially reduced gender inequality. Financial inclusion access was found to drive down gender inequality more than usage. Female educational levels were found to have a substantial but negative impact on gender inequality. This study recommends that there is a need for an increase in commercial bank branches to increase accessibility to financial services. The government should increase its expenditure, and this should be channelled towards financial development and higher levels of education for females to improve financial literacy.

scholarly journals Needs assessment and impact of COVID-19 on pharmacy professionals in 31 commonwealth countries

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Diane Ashiru-Oredope ◽  
◽  
Amy Hai Yan Chan ◽  
Omotayo Olaoye ◽  
Victoria Rutter ◽  
...  
Keyword(s):  
Global Health ◽  
Emergency Preparedness ◽  
World Health ◽  
Global Public Health ◽  
Online Questionnaire ◽  
Health Crisis ◽  
Frequency Distributions ◽  
The World ◽  
Pandemic Response ◽  
The Impact

Abstract Background The declaration of COVID-19 a pandemic by the World Health Organization on 11 March 2020 marked the beginning of a global health crisis of an unprecedented nature and scale. The approach taken by countries across the world varied widely, however, the delivery of frontline healthcare was consistently recognised as being central to the pandemic response. This study aimed to identify and explore the issues currently facing pharmacy teams across Commonwealth countries during the COVID-19 pandemic. The study also evaluates pharmacy professionals’ understanding of key knowledge areas from the COVID-19 webinar hosted by the Commonwealth Pharmacists’ Association (CPA). Method A quantitative survey-based approach was adopted, using a 32-item questionnaire developed from the literature on pharmacy and pandemic response. The survey was hosted on Survey Monkey and pilot tested. The final survey was disseminated by CPA member organisations. A 6-item online questionnaire was sent via email to all attendees of CPA's COVID-19 webinar. Descriptive statistics on frequency distributions and percentages were used to analyse the responses. Data were analysed using Microsoft® Excel (2010). Results There were 545 responses from pharmacy professionals across 31/54 Commonwealth countries in Africa, Asia, the Americas, Europe and the Pacific. Majority of the respondents reported being at least somewhat worried (90%) and more than 65% were very worried or extremely about the impact of COVID-19 on them personally and professionally. Nearly two-thirds of respondents stated finding it somewhat difficult or very difficult to work effectively during the pandemic. Challenges mostly faced by pharmacy professionals working remotely included; general anxiety about the impact of COVID-19 on their lives (12%), and difficulties in communicating with their co-workers (12%). Most pharmacy professionals had not previously been actively involved in a global health emergency (82%) nor obtained training on global/public health emergency preparedness (62%). Between 45 and 97% of the COVID-19 webinar attendees provided the correct answers to post-webinar questions, suggesting some improvement in knowledge. Conclusion Our study confirms pharmacy professionals’ concerns about practice during a pandemic and provides preliminary data on the challenges and learning needs of the profession. The CPA has since acted on these findings, providing ongoing opportunities to develop and refine resources for the profession as the pandemic evolves. Pharmacy professionals have also demonstrated improved knowledge on the management of COVID-19 and resources available for professionals.

scholarly journals Conditional Efficiency of Official Development Assistance (ODA) on Economic Growth in Sub-Saharan Africa

2020 ◽  
Vol 16 (1) ◽  
pp. 1
Author(s):  
Ladifatou GACHILI NDI GBAMBIE ◽  
Ousseni MONGBET
Keyword(s):  
Economic Growth ◽  
Economic Policy ◽  
Negative Impact ◽  
Social Situation ◽  
Sub Saharan Africa ◽  
Method Of Moment ◽  
Sub Saharan ◽  
The Impact ◽  
Ssa Countries

<p>Sub-Saharan Africa (SSA) countries have benefited for more than fifty years from international aid in the form of loans and/or donations. Nevertheless, they seem not to benefit from these massive financial resources (ODA) they receive because their economic and social situation is not very good. This study aims to assess the impact of ODA on economic growth in SSA and to see if its effect on growth is conditioned by the quality of the economic policy. The estimates are conducted on a dynamic panel of twenty-three SSA countries running from 1985 to 2014. With macroeconomic data from the World Bank's CD-ROM (World Development Indicators, 2015), the Generalized Method of Moment (GMM) system from Blundel and Bond (1998) was used. The results show that the impact of ODA on growth is not significant. Subsequently, when squared aid (ODA2) is included in the estimate, ODA becomes significant, meaning that a substantial amount of assistance is required to be effective in raising the economic growth rate of the SSA countries. In addition, the effectiveness of ODA is conditioned by the quality of the economic policy. This seems to be bad in SSA, hence the negative impact of the aid on economic growth.</p>

scholarly journals Impact of Covid-19 on Stock Market in Sub-Saharan Africa

2021 ◽  
Vol 1 (2) ◽  
pp. 41-70
Author(s):  
Saifullahi Adam Bayero ◽  
Babangida Danladi Safiyanu ◽  
Zaitun Sanusi Bakabe
Keyword(s):  
Stock Markets ◽  
Negative Impact ◽  
Virus Disease ◽  
Selection Criterion ◽  
Sub Saharan Africa ◽  
World Health ◽  
African Countries ◽  
The World ◽  
Sub Saharan ◽  
The Impact

Corona virus disease (COVID-19) which was declared by the World Health Organization as a global pandemic caused serious economic problem to all the countries including Sub-Saharan Africa. Given the negative impact of COVID19 on the world economy, this paper examined the impact of COVID19 related cases and death on stock exchange markets volatility in Sub-Saharan African countries. The study used the number of reported cases and death from four Sub-Saharan African countries viz Nigeria, South Africa, Kenya, and Botswana, reported cases and death from China and U.S. and all share index as a proxy of stock markets in four countries from 28 February 2020 to 21 December 2020. The study estimated GARCH 11, TGARCH 11, and EGARCH 11 since the variables are heteroskadestic in nature which makes the application of ARCH lausible; the selection criterion was based on Akaike, Schwarz, and Hannan info Criteria. The result shows that COVID19 confirmed cases and death do not affect the operation of the stock markets in Sub-Saharan African countries, but the volatility of the markets has increased within the period of analysis. Furthermore, Botswana and Kenya stock markets were affected by external cases from China. We therefore recommended that stock markets stakeholders in Sub-Saharan Africa should be more concern about health safety measures and be ready for any future pandemic that might affect the markets.

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