scholarly journals Medicinal Plants in COVID-19: Potential and Limitations

2021 ◽  
Vol 12 ◽  
Author(s):  
Xin Yi Lim ◽  
Bee Ping Teh ◽  
Terence Yew Chin Tan
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Low Income ◽  
Nigella Sativa ◽  
Immunomodulatory Effects ◽  
Eurycoma Longifolia ◽  
Low Income Groups ◽  
Anti Inflammatory ◽  
Novel Coronavirus ◽  
Evidence Summaries

Currently, the search to identify treatments and vaccines for novel coronavirus disease (COVID-19) are ongoing. Desperation within the community, especially among the middle-and low-income groups acutely affected by the economic impact of forced lockdowns, has driven increased interest in exploring alternative choices of medicinal plant-based therapeutics. This is evident with the rise in unsubstantiated efficacy claims of these interventions circulating on social media. Based on enquiries received, our team of researchers was given the chance to produce evidence summaries evaluating the potential of complementary interventions in COVID-19 management. Here, we present and discuss the findings of four selected medicinal plants (Nigella sativa, Vernonia amygdalina, Azadirachta indica, Eurycoma longifolia), with reported antiviral, anti-inflammatory, and immunomodulatory effects that might be interesting for further investigation. Our findings showed that only A. indica reported positive antiviral evidence specific to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) based on preliminary in silico data while all four medicinal plants demonstrated differential anti-inflammatory or immunomodulatory effects. The definitive roles of these medicinal plants in cytokine storms and post-infection complications remains to be further investigated. Quality control and standardisation of medicinal plant-based products also needs to be emphasized. However, given the unprecedented challenges faced, ethnopharmacological research should be given a fair amount of consideration for contribution in this pandemic.

Medicinal Herbs with Anti-Inflammatory Activities for Natural and Organic Healing

2021 ◽  
Vol 25 ◽  
Author(s):  
Mohamad Hesam Shahrajabian
Keyword(s):  
Herbal Medicine ◽  
Medicinal Plants ◽  
Cannabis Sativa ◽  
Inflammatory Diseases ◽  
Nigella Sativa ◽  
Centella Asiatica ◽  
Medicinal Herbs ◽  
Scientific Publications ◽  
Anti Inflammatory ◽  
Clinical Experiments

: One of the principal causes of different disorders is an uncontrolled inflammatory response. Alkaloids, flavonoids, polyphenolic, proanthocyanidin, terpenoid, and steroid compounds are the main reasons for the anti-inflammatory activities of medicinal herbs and plants. The current manuscript introduces a series of potential anti-inflammatory plants, particularly those which are routines in Iranian and Chinese traditional herbal medicine, and simplifies the function and mechanisms of natural constituents for the prevention and treatment of inflammatory disorders. PubMed, Science Direct, Google Scholar, Wiley Online Library, Springer, Taylor, Francis, etc., have been used to search for collecting of scientific publications for a full evaluation of current documentation in the literature showing the importance of medicinal plants with anti-inflammatory characteristics and natural medicines. The most notable medicinal plants with anti-inflammatory activities are Baccharis dracunculifolia, Aconitum bulleyanum, Crateya adansonii, Alliums spp., Centella asiatica, Flos lonicerae, Corydalis dubia, Syringae folium, Coptis chinensis, Casearia decandra, Nigella sativa, Cannabis sativa, Tamarindus indica L., Glycyrrhiza glabra, Panax ginseng, Panax notoginseng, Pistacia vera, Smilax china, Scutellaria baicalensis, Rosemarinus officinalis, Moringa olifera, Pulsatilla radix, Pistacia atlantica, Rullia tuberose, Canarium album, Dodonaea polyandra, Forsythia suspense, Polygala tenuifolia, Radiz Isatidis, Hypericum sampsonii, Geranium koreanum, Typha capensis, Isatidis folium, Ginkgo biloba, Houttuynia cordata, snow lotus, etc. Herbal medicine mainly uses numerous parts of plants or combinations of them to prevent and remedy diseases and promote health. More investigations and clinical experiments are needed to provide more information on the importance of medicinal plants as well as their roles in the treatment and prevention of inflammatory diseases.

scholarly journals FEATURES OF THE STRUCTURE OF NATURAL POPULATIONS HUMULUS LUPULUS L. (REVIEW)

2020 ◽  
Vol 1 (337) ◽  
pp. 33-40
Author(s):  
Yedilova A.K. ◽  
Inelova Z.A.
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Natural Populations ◽  
Humulus Lupulus ◽  
Biologically Active ◽  
Humulus Lupulus L ◽  
Wide Range ◽  
Anti Inflammatory ◽  
Beer Production

The article provides an overview of the structural features of the natural populations of Humulus lupulus L. in the world and in Kazakhstan. Currently, the use in medicine of natural products, medicines and biologically active substances of plant origin is increasing. Significant parts of the medicinal raw materials are wild plants. The need for medicinal plant raw materials (medicinal plants) is not decreasing; the technology of its procurement and reproduction in natural conditions wants significant perfection. It is known that they have a milder, more complex effect on the human body and are used in the treatment of many chronic diseases. The growing anthropogenic impact on populations of valuable medicinal plants is decreasing their stocks of raw materials. In this regard, the study of biological characteristics and the development of scientifically based agricultural techniques for the cultivation of many medicinal plants are becoming relevant. Humulus lupulus L. (common hop) is a valuable medicinal plant. They are used as painkillers, sedatives, hypnotics for increased nervous irritability, sleep distur-bances, neuralgia, vegetovascular dystonia, mild coronary spasms, tachycardia, and in the early stages of hyper-tension. According to the classification of medicinal plant resources, Humulus lupulus L. is a plant with a wide range, but with a limited supply of raw materials. In places of growth of Humulus lupulus L. does not form large thickets [1]. Recently, a comprehensive approach has been applied in the study of natural plant populations, including ontomorphological and population-ecological studies. This makes it possible to objectively assess the state of the species in the cenosis and predict its future behavior. In this regard, a comprehensive study of the natural populations of Humulus lupulus L. is of great relevance. Hops (Humulus lupulus L.) is an important crop worldwide, known as the main flavor ingredient in beer. A diversified brewing industry requires a variety of flavors, superior technological properties and sustainable agro-nomy, which are the center of advanced molecular breeding efforts in hops. Hop breeders have been limited in their ability to create strains with desirable traits, however, due to unusual and unpredictable inheritance patterns and the associated non-Mendelian segregation of genetic markers [2]. The use of hops has recently been undergoing a new change, driven by a growing international preference for more intensely flavored beer, supported by the craft-brewing sector. This movement led to the introduction of much more hops at various stages of beer production and to an ever-growing search for new flavors. Some hop varieties have thus received particular attention, including several older typical hops mostly used to date, although an intensive search for new varieties dubbed "Green Gold" has also taken place. A large number of new exquisite varieties have been described and are increasingly appreciated in the market. Global hop growing areas have increased over the past 5 years, although total world beer production has declined over the same period, confirming the trend of using more hops per liter of beer. In addition, a wide range of pharmacological properties have been described for hops and its derivatives, namely antioxidant, anti-inflammatory and antitumor properties, which are of great importance for the pharmaceutical industry. The bioactivity of beer can depend on the use of hops, which can become an important tool for brewers aiming to develop functional products. Taken together, the compounds isolated from Humulus lupulus L. have a wide range of biological activity, such as anti-inflammatory action, antimicrobial action, antioxidant action, antiproliferative effects, cytochrome P450 effects, glucose metabolism effects, hormonal effects, lipid effects and sedative / hypnotic effects. Therefore, the purpose of this Chapter is to describe the importance of hops in this new direction of beer production, market overview of hops, varieties, forms and methods of use, composition, value in bioactivity of beer and new discoveries in research hops [3].

scholarly journals Examining the Impact of the 2019 Novel Coronavirus and Pandemic-Related Hardship on Adverse Pregnancy and Infant Outcomes: Design and Launch of the HOPE COVID-19 Study

2020 ◽  
Vol 1 (2) ◽  
pp. 91-107
Author(s):  
Laura L. Jelliffe-Pawlowski ◽  
Scott P. Oltman ◽  
Larry Rand ◽  
Karen A. Scott ◽  
Miriam Kuppermann ◽  
...  
Keyword(s):  
Low Income ◽  
Well Being ◽  
Infant Outcomes ◽  
Marginalized Communities ◽  
Mobile Phone Application ◽  
Study Results ◽  
Low Income Groups ◽  
Adverse Pregnancy ◽  
Novel Coronavirus ◽  
The Impact

The 2019 novel coronavirus disease (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and worsen in many parts of the world. As the pandemic grows, it is especially important to understand how the virus and the pandemic are affecting pregnant women and infants. While early data suggested that being infected with the virus did not increase the risk of adverse pregnancy or infant outcomes, as more information has emerged, it has become clear that risks for some adverse pregnancy and infant outcomes are increased (e.g., preterm birth, cesarean section, respiratory distress, and hospitalization). The Healthy Outcomes of Pregnancy for Everyone in the time of novel coronavirus disease-19 (HOPE COVID-19) study is a multi-year, prospective investigation designed to better understand how the SARS-CoV-2 virus and COVID-19 impact adverse pregnancy and infant outcomes. The study also examines how the pandemic exacerbates existing hardships such as social isolation, economic destabilization, job loss, housing instability, and/or family member sickness or death among minoritized and marginalized communities. Specifically, the study examines how pandemic-related hardships impact clinical outcomes and characterizes the experiences of Black, Latinx and low-income groups compared to those in other race/ethnicity and socioeconomic stratum. The study includes two nested cohorts. The survey only cohort will enroll 7500 women over a two-year period. The survey+testing cohort will enroll 2500 women over this same time period. Participants in both cohorts complete short surveys daily using a mobile phone application about COVID-19-related symptoms (e.g., fever and cough) and complete longer surveys once during each trimester and at 6–8 weeks and 6, 12 and 18 months after delivery that focus on the health and well-being of mothers and, after birth, of infants. Participants in the survey+testing cohort also have testing for SARS-CoV-2 and related antibodies during pregnancy and after birth as well as testing that looks at inflammation and for the presence of other infections like Influenza and Rhinovirus. Study results are expected to be reported on a rolling basis and will include quarterly reporting for participants and public health partners as well as more traditional scientific reporting.

scholarly journals AN UPDATED PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW ON GYNURA PROCUMBENS

2019 ◽  
pp. 9-14 ◽  
Author(s):  
KAMRAN ASHRAF
Keyword(s):  
Experimental Data ◽  
Side Effects ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Traditional Medicine ◽  
Therapeutic Potential ◽  
Therapeutic Uses ◽  
Pharmacological Studies ◽  
Anti Inflammatory ◽  
Effective Drugs

Nowadays, the use of medicinal plants increased significantly for the aim of producing more effective drugs with fewer side effects. Gynura procumbens (family Asteraceae) is a high value medicinal plant with different properties that are considered less, regardless of having great therapeutic potential in traditional medicine. Many pharmacological studies have established the ability of this plant to exhibit antimicrobial, antioxidant, hepatoprotection, antigenotoxic, antiplasmodial, cytotoxic, cardioactive, antidiabetic, anti-inflammatory, etc. The aim of this study was to review the updated phytochemical, pharmacological investigations as well as the traditional and therapeutic uses of G. procumbens. Important and different experimental data have been addressed along with a review of most of the phytochemicals identified in this plant.

scholarly journals Ethnobotanical survey of medicinal plants in Yilmana Densa and Quarit Districts, West Gojjam, Western Ethiopia

2020 ◽  
Author(s):  
Derebe Alemneh
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Cultural Values ◽  
Nigella Sativa ◽  
Conservation Strategy ◽  
Ex Situ ◽  
Anthropogenic Factors ◽  
Structured Interviews ◽  
Ethnobotanical Survey ◽  
Phytolacca Dodecandra

Abstract Background: Traditional herbal preparations for addressing human diseases and ailments have been applied in Yilmana Densa and Quarit Districts, Ethiopia, for generations. However, the medicinal knowledge of the community and the plants are subjected to loss without being scientifically documented due to anthropogenic factors. Hence, this study aims at providing a comprehensive documentation on medicinal plant knowledge of the people to conserve the knowledge and medicinal plants of the areas.Methods: Semi-structured interviews, focus group discussions, participant observation, field observation and market survey were used to collect ethnobotanical data. All semi-structured interviews were followed by independent walk in the woods exercises. Field observations were performed with the help of local guides. The data analysis methods were informant consensus factor and fidelity level, frequency and cultural significance indices, preference and direct matrix ranking exercises. Results: A total of 112 medicinal plants were reported. Fabaceae was represented with highest species. Leaves were the primary source of remedy. Most remedy was prepared by pounding and administered orally. Miscellaneous, central nervous and digestive system diseases were recorded with highest informant agreements while Dodonia angustifolia, Dovyalis abyssinica, Hagenia abyssinica, Nigella sativa and Urtica simensis were recorded with highest healing potential for malaria, tapeworm, cough, stomach ulcer respectively. Phytolacca dodecandra, Trigonella foenum-graecum, and Carissa spinarum and Croton macrostachyus were recorded with highest frequency, use, and cultural values respectively. Verbascum sinaiticum was the most preferred to treat blood pressure Conclusion: The study indicated that indigenous knowledge on medicinal plant use is still rich and active in the Districts. Species with recorded highest consensus for curative role are a useful pool for further phytochemical and pharmacological validation for better utilization. Declining medicinal flora of the area calls for implementation of a coordinated complementary in situ and ex situ conservation strategy.

scholarly journals Antioxidant and Anti-Inflammatory Activities of Kenyan Leafy Green Vegetables, Wild Fruits, and Medicinal Plants with Potential Relevance for Kwashiorkor

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
H. R. Tufts ◽  
C. S. Harris ◽  
Z. N. Bukania ◽  
T. Johns
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Phenolic Content ◽  
Mangifera Indica ◽  
Acute Malnutrition ◽  
Total Phenolic ◽  
Wild Fruits ◽  
Prevention And Treatment ◽  
Anti Inflammatory

Background.Inflammation, together with related oxidative stress, is linked with the etiology of kwashiorkor, a form of severe acute malnutrition in children. A diet rich in anti-inflammatory and antioxidant phytochemicals may offer potential for the prevention and treatment of kwashiorkor. We selected and assayed five leafy green vegetables, two wild fruits, and six medicinal plants from Kenya for their antioxidant and anti-inflammatory properties. Consensus regarding medicinal plant use was established from ethnobotanical data.Methods. Antioxidant activity and phenolic content were determined using the oxygen radical absorbance capacity (ORAC) assay and Folin-Ciocalteu procedure, respectively. Anti-inflammatory activity was assessedin vitrotargeting the inflammatory mediator tumour necrosis factor-alpha (TNF-α).Results. Mangifera indica(leaves used medicinally) showed the greatest antioxidant activity (5940 ± 632 µM TE/µg) and total phenolic content (337 ± 3 mg GAE/g) butAmaranthus dubius(leafy vegetable) showed the greatest inhibition of TNF-α(IC50= 9 ± 1 μg/mL), followed byOcimum americanum(medicinal plant) (IC50= 16 ± 1 μg/mL). Informant consensus was significantly correlated with anti-inflammatory effects among active medicinal plants (r2=0.7639, P=0.0228).Conclusions. Several plant species commonly consumed by Kenyan children possess activity profiles relevant to the prevention and treatment of kwashiorkor and warrant further investigation.

scholarly journals Anti-COVID-19 Biomedicines - A Layout Proposal for Production, Storage and Transportation

2021 ◽  
Vol 1 (1) ◽  
pp. 166-188
Author(s):  
Shibabrata Pattanayak
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Infectious Diseases ◽  
Dietary Intake ◽  
Viral Infections ◽  
Plant Parts ◽  
Specific Immunity ◽  
Anti Inflammatory ◽  
Prevention And Cure ◽  
Selection Of

Background: Modulation of non-specific immunity and other related activities of succulent parts of effective medicinal plants can prevent viral infections like COVID-19 through their dietary intake. Objective: The succulent parts of the medicinal plants with immunomodulation, anti-oxidation, anti-viral, anti-inflammatory, etc. power can be used orally in the capsular form to prevent as well as to reduce the severity of symptoms of COVID-19. Methods: A proposal is displayed with a detailed description of related steps like the selection of medicinal plant parts consulting related reports, collection of biomedicines, validation of efficacy, dosing, encapsulation, storage, and transportation, etc. Results: The succulent bio-medicines against COVID-19 can be developed and marketed following only some adoptive research. Conclusion: Succulent bio-medicines can be prepared and marketed for the prevention and cure of different infectious and non-infectious diseases.

Brahmi (Bacopa monnieri): Up-to-date of memory boosting medicinal plant: A review

2016 ◽  
Vol 50 (1) ◽  
Author(s):  
Natthawut Charoenphon ◽  
Nanthida Anandsongvit ◽  
Piya Kosai ◽  
Kanjana Sirisidthi ◽  
Niwat Kangwanrangsan ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Antioxidant Properties ◽  
Bacopa Monnieri ◽  
Respiratory Problems ◽  
Traditional Medicinal Plants ◽  
Anti Inflammatory ◽  
Anxiety Depression

<italic>Bacopa monnieri</italic>, Family: Plantaginaceae, known as water hyssop, herb of grace or Indian penny wort, is one of the traditional medicinal plants in Ayurveda medicine, where it is also called Brahmi, a name derived from Brahma, the creator God of the Hindu Pantheon. It is now being widely promoted to enhance memory, learning and concentration and also to treat anxiety, depression, and systemic disorders like cardiovascular, gastrointestinal, hepatic, neurological and also respiratory problems. Further, Brahmi has been shown to possess anticancer, antidiabetic, anti-inflammatory, antimicrobial and antioxidant properties. Its phytochemical substances are alkaloids, flavonoids, glycosides, saponins, and the important constituents such as bacosides, bacopasides, and bacopasaponins, which all of these contribute to its remedial properties. This article provides a brief overview of the memory boosting activity of brahmi, (<italic>B. monnieri</italic>), to further provide an upto-date review showing its importance especially, memory boosting.

scholarly journals The effects of magnetic water treatment for improving germination of some medicinal plants

2018 ◽  
Vol 12 (2) ◽  
pp. 61-65
Author(s):  
Khalid A. Rasheed ◽  
Sattar Shlahi ◽  
Hayder H. Ismail ◽  
Mohammed Omar Abdullateef
Keyword(s):  
Water Treatment ◽  
Medicinal Plants ◽  
Magnetic Fields ◽  
Medicinal Plant ◽  
Nigella Sativa ◽  
Eruca Sativa ◽  
Plant Seed ◽  
Temperature Levels ◽  
Growth Experiments ◽  
Magnetic Water

      Three magnetic fields (2000,3000 and 4000) guass were used to study the germination of five types of medicinal plant seed (Nigella sativa, Coriandrum sativum, Cuminum cyminum, Eruca sativa and Foenicutum. vulgare). The seeds were incubated in the dark and in certain moisture at three different temperature levels (10, 18 and 22)°C for 14 days. During the growth experiments, the best temperature of germination was found at 18°C, where it excelled three seed of five and gave a high percentage of germination to F. vulgare E. sativa C. sativum. Magnetic fields showed a differential effect in plant seed with different temperature. Where the seeds of F. vulgare and C. sativum gave the highest percentage of germination at 18°C.

scholarly journals Botanical and phyto-pharmacological reports on Stephania japhonica

2017 ◽  
Vol 2 (01) ◽  
pp. 1-7 ◽  
Author(s):  
Muhammad Torequl Islam ◽  
Mohammad Hossain ◽  
Md. Abul Kalam Azad ◽  
Syed Mohammed Tareq
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Human Health ◽  
Skin Diseases ◽  
Folk Medicine ◽  
Urinary Disorders ◽  
Plant Parts ◽  
Anti Inflammatory ◽  
Analgesic Activities ◽  
A Current

Medicinal plants play a key role in the human health. The use of plants, plant parts and their derived products is ancient. To date, a number of medicinal plants have gained attention of the medicinal scientists for their important phytoconstituents and in the treatment of various diseases. The plants of the genus Stephania (Family: Menispermaceae) are widely distributed, and are being used in the folk medicine for the treatment of various ailments, such as asthma, tuberculosis, fever, dysentery, hyperglycemia, malaria, and cancer. Stephania japonica belonging to this genus has been reported for many important phytochemicals and folk usages in the treatment of fever, diarrhea, dyspepsia, convulsions, skin diseases, cough, asthma, and urinary disorders. The scientific evidences suggest that, S. japonica has antioxidant, anti-inflammatory, antibacterial, antifungal, cytotoxic, anti-diabetic, anti-diarrheal, and analgesic activities. This review presents a current morphological and phyto-pharmacological scenario on this hopeful medicinal plant.

Sign in / Sign up

Export Citation Format

Share Document