scholarly journals Phenolic Compounds From Brewer's Spent Grains: Toward Green Recovery Methods and Applications in the Cosmetic Industry

2021 ◽  
Vol 5 ◽  
Author(s):  
Rodrigo Macias-Garbett ◽  
Sergio Othón Serna-Hernández ◽  
Juan Eduardo Sosa-Hernández ◽  
Roberto Parra-Saldívar
Keyword(s):  
Phenolic Compounds ◽  
Low Cost ◽  
Antioxidant Properties ◽  
Economic Feasibility ◽  
Bioactive Molecules ◽  
Added Value ◽  
Anticancer Activities ◽  
Cosmetic Industry ◽  
Potential Applications ◽  
Pharmaceutical Industries

Brewers' spent grain (BSG) is the main by-product derived from the brewing industry, where it accounts for 85% of the total waste generated. The total annual production worldwide of this waste is 39 million tons. This lignocellulosic material is traditionally used as cattle feed and sold at a low retail price (~USD 45.00 per ton). However, efforts for the revalorization of this by-product are emerging since research has established that it can be used as a low-cost source of bioactive molecules and commodity chemicals that can bring value to integral biorefinery ventures. Among commodities, phenolic compounds have attracted attention as added-value products due to their antioxidant properties with applications in the food, cosmetic, and pharmaceutical industries. These phytochemicals have been associated with antiaging and anticancer activities that have potential applications on cosmetic products. This mini-review summarizes the most relevant extraction techniques used for the recovery of phenolic compounds from BSG while discussing their advantages and shortcomings and the potential applications from BSG bioactive extracts in the cosmetic industry and their reported beneficial effects. This mini-review also makes a brief comment on the role of phenolic compounds extraction in the economic feasibility of an integral BSG biorefinery.

scholarly journals Exploration of the Potential Bioactive Molecules of Tamarillo (Cyphomandra betacea): Antioxidant Properties and Prebiotic Index

2021 ◽  
Vol 11 (23) ◽  
pp. 11322
Author(s):  
Verónica Reyes-García ◽  
Alfonso Totosaus ◽  
Lourdes Pérez-Chabela ◽  
Zaida Nelly Juárez ◽  
Gabriel Abraham Cardoso-Ugarte ◽  
...  
Keyword(s):  
Low Cost ◽  
Scientific Information ◽  
Antioxidant Properties ◽  
Dry Weight ◽  
Good Alternative ◽  
Bioactive Molecules ◽  
Added Value ◽  
Total Phenolic ◽  
Prebiotic Activity ◽  
Chemical Structures

Tamarillo is an alternative for the consumption of food with high added value through various technological methodologies with nutritional quality and low cost, generating an economic impact on society. The objective of this research was to evaluate the potential of tamarillo red variety, as a source of bioactive compounds, to generate scientific information on the importance of its chemical composition and antioxidant and prebiotic properties. Different analyses were carried out: spectroscopic methods (IR, UV, NMR) of pulp flour and epicarp flour, antioxidant properties, prebiotic activity, and bromatological analysis. The spectra obtained by FTIR, UV, and NMR allowed the identification of chemical structures associated with the inulin-like functional groups. Pulp flour showed the highest prebiotic activity with values of 1.49 for Lactiacidbacillus. plantarum. Total phenolic compounds content in epicarp flour was 206.23 mg/100 g dry weight, with an acceptable antioxidant property (ABTS+ = 6.27 TEAC and DPPH= %AA of 91.74 at a concentration of 250.00 µg/mL, 131.26 of IC50 ascorbic acid). The results regarding tamarillo as a source of bioactive molecules with important physiological properties as an antioxidant and putative prebiotic indicate it is a good alternative for the formulation of functional foods.

scholarly journals Seaweed-Based Molecules and Their Potential Biological Activities: An Eco-Sustainable Cosmetics

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5313
Author(s):  
Haresh S. Kalasariya ◽  
Virendra Kumar Yadav ◽  
Krishna Kumar Yadav ◽  
Vineet Tirth ◽  
Ali Algahtani ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Biological Activities ◽  
Antioxidant Properties ◽  
Industrial Applications ◽  
Biologically Active ◽  
Marine Macroalgae ◽  
Bioactive Molecules ◽  
Bioactive Constituents ◽  
Promising Alternative ◽  
Cosmetic Industry

Amongst the countless marine organisms, seaweeds are considered as one of the richest sources of biologically active ingredients having powerful biological activities. Seaweeds or marine macroalgae are macroscopic multicellular eukaryotic photosynthetic organisms and have the potential to produce a large number of valuable compounds, such as proteins, carbohydrates, fatty acids, amino acids, phenolic compounds, pigments, etc. Since it is a prominent source of bioactive constituents, it finds diversified industrial applications viz food and dairy, pharmaceuticals, medicinal, cosmeceutical, nutraceutical, etc. Moreover, seaweed-based cosmetic products are risen up in their demands by the consumers, as they see them as a promising alternative to synthetic cosmetics. Normally it contains purified biologically active compounds or extracts with several compounds. Several seaweed ingredients that are useful in cosmeceuticals are known to be effective alternatives with significant benefits. Many seaweeds’ species demonstrated skin beneficial activities, such as antioxidant, anti-melanogenesis, antiaging, photoprotection, anti-wrinkle, moisturizer, antioxidant, anti-inflammatory, anticancer and antioxidant properties, as well as certain antimicrobial activities, such as antibacterial, antifungal and antiviral activities. This review presents applications of bioactive molecules derived from marine algae as a potential substitute for its current applications in the cosmetic industry. The biological activities of carbohydrates, proteins, phenolic compounds and pigments are discussed as safe sources of ingredients for the consumer and cosmetic industry.

scholarly journals Oxidative Stress and Marine Carotenoids: Application by Using Nanoformulations

Marine Drugs ◽  
2020 ◽  
Vol 18 (8) ◽  
pp. 423 ◽  
Author(s):  
Yasin Genç ◽  
Hilal Bardakci ◽  
Çiğdem Yücel ◽  
Gökçe Şeker Karatoprak ◽  
Esra Küpeli Akkol ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Properties ◽  
Chemical Diversity ◽  
Biologically Active ◽  
Bioactive Molecules ◽  
Photosynthetic Organisms ◽  
Stress Markers ◽  
Potential Applications ◽  
Health Promoting ◽  
Cancer Types

Carotenoids are natural fat-soluble pigments synthesized by plants, algae, fungi and microorganisms. They are responsible for the coloration of different photosynthetic organisms. Although they play a role in photosynthesis, they are also present in non-photosynthetic plant tissues, fungi, and bacteria. These metabolites have mainly been used in food, cosmetics, and the pharmaceutical industry. In addition to their utilization as pigmentation, they have significant therapeutically applications, such as improving immune system and preventing neurodegenerative diseases. Primarily, they have attracted attention due to their antioxidant activity. Several statistical investigations indicated an association between the use of carotenoids in diets and a decreased incidence of cancer types, suggesting the antioxidant properties of these compounds as an important factor in the scope of the studies against oxidative stress. Unusual marine environments are associated with a great chemical diversity, resulting in novel bioactive molecules. Thus, marine organisms may represent an important source of novel biologically active substances for the development of therapeutics. Marine carotenoids (astaxanthin, fucoxanthin, β-carotene, lutein but also the rare siphonaxanthin, sioxanthin, and myxol) have recently shown antioxidant properties in reducing oxidative stress markers. Numerous of bioactive compounds such as marine carotenoids have low stability, are poorly absorbed, and own very limited bioavailability. The new technique is nanoencapsulation, which can be used to preserve marine carotenoids and their original properties during processing, storage, improve their physiochemical properties and increase their health-promoting effects. This review aims to describe the role of marine carotenoids, their potential applications and different types of advanced nanoformulations preventing and treating oxidative stress related disorders.

scholarly journals Essential Oils and Their Individual Components in Cosmetic Products

Cosmetics ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 114
Author(s):  
Eduardo Guzmán ◽  
Alejandro Lucia
Keyword(s):  
Essential Oils ◽  
Antioxidant Properties ◽  
Cosmetic Products ◽  
Active Ingredients ◽  
Design And Optimization ◽  
Cosmetic Industry ◽  
International Regulations ◽  
Potential Applications ◽  
The Many ◽  
Botanical Extract

The current consumer demands together with the international regulations have pushed the cosmetic industry to seek new active ingredients from natural renewable sources for manufacturing more eco-sustainability and safe products, with botanical extract being an almost unlimited source of these new actives. Essential oils (EOs) emerge as very common natural ingredients in cosmetics and toiletries as a result of both their odorous character for the design and manufacturing of fragrances and perfumes, and the many beneficial properties of their individual components (EOCs), e.g., anti-inflammatory, antimicrobial and antioxidant properties, and, nowadays, the cosmetic industry includes EOs or different mixtures of their individual components (EOCs), either as active ingredients or as preservatives, in various product ranges (e.g., moisturizers, lotions and cleanser in skin care cosmetics; conditioners, masks or antidandruff products in hair care products; lipsticks, or fragrances in perfumery). However, the unique chemical profile of each individual essential oil is associated with different benefits, and hence it is difficult to generalize their potential applications in cosmetics and toiletries, which often require the effort of formulators in seeking suitable mixtures of EOs or EOCs for obtaining specific benefits in the final products. This work presents an updated review of the available literature related to the most recent advances in the application of EOs and EOCs in the manufacturing of cosmetic products. Furthermore, some specific aspects related to the safety of EOs and EOCs in cosmetics will be discussed. It is expected that the information contained in this comprehensive review can be exploited by formulators in the design and optimization of cosmetic formulations containing botanical extracts.

scholarly journals Comparative Insight upon Chitosan Solution and Chitosan Nanoparticles Application on the Phenolic Content, Antioxidant and Antimicrobial Activities of Individual Grape Components of Sousão Variety

Antioxidants ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 178
Author(s):  
Vanessa Silva ◽  
Rupesh Kumar Singh ◽  
Nelson Gomes ◽  
Bruno Gonçalves Soares ◽  
Adriana Silva ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Chitosan Nanoparticles ◽  
Chitosan Solution ◽  
Antimicrobial Activities ◽  
Added Value ◽  
Diffusion Method ◽  
Total Phenolic ◽  
Resistant Bacteria ◽  
Pharmaceutical Industries ◽  
Antioxidant And Antimicrobial Activities

Chitosan, a natural polysaccharide, has been previously proposed as an elicitor in plants to prevent pathogen infections. The present study aimed to analyze the effect of chitosan solution and chitosan nanoparticles treatment applied on the grapevine variety Sousão with respect to the phenolic composition, antioxidant potential and antibacterial activity of its individual grape components. Grapevine plants of selected lines were sprayed with chitosan solution and chitosan nanoparticles, and ethanolic extracts of stems, seeds and skins were prepared from grapevines treated and not treated with chitosan. Total phenolic, anthocyanin and tannin contents were studied, and the identification of the individual phenolic compounds was performed by HPLC-DAD. The antimicrobial susceptibility method was performed using the Kirby-Bauer disc diffusion method against multidrug-resistant bacteria. Overall, there was small increase in the concentration of phenolic compounds, antioxidant and antimicrobial activities in grape components treated with chitosan solution. Seed extracts showed the highest antioxidant and antimicrobial activities. The studied individual components obtained from chitosan-treated grapevines could represent an added value due to the increased antioxidant and antibacterial potentials. The phenolic compounds found in components may be used in food and pharmaceutical industries as natural food preservers and antibiotic adjuvants.

scholarly journals River Tea Tree Oil: Composition, Antimicrobial and Antioxidant Activities, and Potential Applications in Agriculture

Plants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2105
Author(s):  
Mursleen Yasin ◽  
Adnan Younis ◽  
Talha Javed ◽  
Ahsan Akram ◽  
Muhammad Ahsan ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Bacterial Species ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Butylated Hydroxytoluene ◽  
Tea Tree Oil ◽  
Tea Tree ◽  
Potential Applications ◽  
Pharmaceutical Industries

Melaleuca is one of the genera of the Myrtaceae family enriched in tea tree oil (TTO). Tea tree oils of Melaleuca bracteata and Melaleuca alternifolia are of prime importance and have antioxidant and antimicrobial properties. Terpinen-4-ol and 1-8 cineole are major constituents of M. alternifolia oil. The percentages of the compounds in the oils can slightly vary according to the region of plant harvest, the distillation technique, or the part of the plant used for oil extraction. TTO has a bactericidal effect against various bacterial species such as Bacillus cereus, B. subtilis, E. coli, Pseudomonas putida, and S. aureus. Several reports proved that this essential oil is also effective against fungal strains of Fusarium, Aspergillus, and Candida species. It also has antioxidant properties such as radical scavenging activity and reducing power. The antioxidant properties of TTO at a concentration of 30 mM were observed to be greater than those of butylated hydroxytoluene (BHT), commonly used as a synthetic antioxidant. TTO is also an effective organic fungicide, herbicide, and insecticide for use in the agriculture sector. Postharvest application of the oil has been found efficient on sweet basil, citrus, and strawberry. It is concluded that tea tree oil has the potential to be used in the food, agriculture, and pharmaceutical industries as a natural antimicrobial and preservative agent. This review provides comprehensive information regarding the antioxidant and antimicrobial activities of tea tree oil and its potential applications in agriculture.

scholarly journals Microbial Biosurfactant: A New Frontier for Sustainable Agriculture and Pharmaceutical Industries

Antioxidants ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1472
Author(s):  
Ajay Kumar ◽  
Sandeep Kumar Singh ◽  
Chandra Kant ◽  
Hariom Verma ◽  
Dharmendra Kumar ◽  
...  
Keyword(s):  
Disease Management ◽  
Soil Quality ◽  
Plant Disease ◽  
Antioxidant Properties ◽  
Climatic Conditions ◽  
Limiting Factors ◽  
Anticancer Activities ◽  
Wide Range ◽  
Pharmaceutical Industries ◽  
Plant Disease Management

In the current scenario of changing climatic conditions and the rising global population, there is an urgent need to explore novel, efficient, and economical natural products for the benefit of humankind. Biosurfactants are one of the latest explored microbial synthesized biomolecules that have been used in numerous fields, including agriculture, pharmaceuticals, cosmetics, food processing, and environment-cleaning industries, as a source of raw materials, for the lubrication, wetting, foaming, emulsions formulations, and as stabilizing dispersions. The amphiphilic nature of biosurfactants have shown to be a great advantage, distributing themselves into two immiscible surfaces by reducing the interfacial surface tension and increasing the solubility of hydrophobic compounds. Furthermore, their eco-friendly nature, low or even no toxic nature, durability at higher temperatures, and ability to withstand a wide range of pH fluctuations make microbial surfactants preferable compared to their chemical counterparts. Additionally, biosurfactants can obviate the oxidation flow by eliciting antioxidant properties, antimicrobial and anticancer activities, and drug delivery systems, further broadening their applicability in the food and pharmaceutical industries. Nowadays, biosurfactants have been broadly utilized to improve the soil quality by improving the concentration of trace elements and have either been mixed with pesticides or applied singly on the plant surfaces for plant disease management. In the present review, we summarize the latest research on microbial synthesized biosurfactant compounds, the limiting factors of biosurfactant production, their application in improving soil quality and plant disease management, and their use as antioxidant or antimicrobial compounds in the pharmaceutical industries.

scholarly journals Terrestrial Microorganisms: Cell Factories of Bioactive Molecules with Skin Protecting Applications

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1836 ◽  
Author(s):  
Laure-Anne Peyrat ◽  
Nikolaos Tsafantakis ◽  
Katerina Georgousaki ◽  
Jamal Ouazzani ◽  
Olga Genilloud ◽  
...  
Keyword(s):  
Low Cost ◽  
Bioactive Molecules ◽  
Added Value ◽  
Pyrrole Derivatives ◽  
Cell Factories ◽  
Enhanced Production ◽  
Different Types ◽  
Terrestrial Environments ◽  
Whitening Activity ◽  
Competition For Resources

It is well known that terrestrial environments host an immense microbial biodiversity. Exposed to different types of stress, such as UV radiation, temperature fluctuations, water availability and the inter- / intra-specific competition for resources, terrestrial microorganisms have been evolved to produce a large spectrum of bioactive molecules. Bacteria, archaea, protists, fungi and algae have shown a high potential of producing biomolecules for pharmaceutical or other industrial purposes as they combine a sustainable, relatively low-cost and fast-production process. Herein, we provide an overview of the different bioactive molecules produced by terrestrial microorganisms with skin protecting applications. The high content in polyphenolic and carotenoid compounds produced by several strains, as well as the presence of exopolysaccharides, melanins, indole and pyrrole derivatives, mycosporines, carboxylic acids and other molecules, are discussed in the context of their antioxidant, photo-protective and skin-whitening activity. Relevant biotechnological tools developed for the enhanced production of high added value natural products, as well as the protecting effect of some antioxidant, hydrolytic and degrading enzymes are also discussed. Furthermore, we describe classes of microbial compounds that are used or have the potential to be used as antimicrobials, moisturizers, biosurfactants, pigments, flavorings and fragrances.

Phenolic production and antioxidant properties of some Macedonian medicinal plants

2014 ◽  
Vol 9 (9) ◽  
pp. 888-900 ◽  
Author(s):  
Oliver Tusevski ◽  
Aneta Kostovska ◽  
Ana Iloska ◽  
Ljubica Trajkovska ◽  
Sonja Simic
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Antioxidant Capacity ◽  
Total Phenolics ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Natural Antioxidants ◽  
Pharmaceutical Industries ◽  
Promising Source

AbstractInvestigations have been made to study the production of phenolic compounds (total phenolics, flavonoids and phenylpropanoids) and total antioxidant capacity in 27 Macedonian traditional medicinal plants to improve its potential as a source of natural antioxidants. Antioxidant potential of plant extracts was analyzed by five different assays: cupric reducing antioxidant capacity (CUPRAC), phosphomolybdenum method (PM), reducing power (RP), 2,2-diphenyl-1-picrylhydrazyl (DPPH·) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS·+) radical scavenging activity. Origanum vulgare extract consistently exhibited the highest content of phenolic compounds and the strongest antioxidant capacity based on the tests performed, and can be proposed as a promising source of natural antioxidants. Melissa officinalis and Salvia ringens were also identified as valuable sources of antioxidant compounds. A positive linear correlation between antioxidant activity and total phenolics, flavonoids and phenylpropanoids indicates that these compounds are likely to be the main antioxidants contributing to the observed activities of evaluated plants. These findings suggest that the medicinal plants studied in this paper are good sources of bioactive compounds for the food and pharmaceutical industries.

scholarly journals Supercritical Fluid Extraction and Stabilization of Phenolic Compounds From Natural Sources – Review (Supercritical Extraction and Stabilization of Phenolic Compounds)

2010 ◽  
Vol 4 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Mário Roberto Maróstica Junior ◽  
Alice Vieira Leite ◽  
Nathalia Romanelli Vicente Dragano
Keyword(s):  
Phenolic Compounds ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Fruits And Vegetables ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Extraction Process ◽  
Fluid Extraction ◽  
Natural Sources ◽  
Pharmaceutical Industries

Phenolic compounds are components commonly found in fruits and vegetables. Recently, they have been subject of considerable scientific and therapeutic interest mainly due to their antioxidant properties and related healthpromoting benefits, as confirmed by the numerous papers devoted to various properties of these compounds. Thus, the extractions of phenolic compounds with functional properties from natural sources have attracted special interests. Supercritical fluid extraction offers a number of advantages over conventional extraction methods above all in relation to the conditions employed during the extraction process that ensures minimal alteration of the active phenolics and the healing properties could be more easily preserved. This work provides an updated overview on the principal applications of Supercritical fluid extraction in recovery of bioactive phenolics emphasizing the effects of temperature, pressure, addition of co-solvents and time on the extraction yield of these compounds and their antioxidant activities for a possible applications in food, cosmetic or pharmaceutical industries.

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