Anxiety and Depression in Adolescents with Severe Asthma and in Their Parents: Preliminary Results after 1 Year of Treatment

Emotional problems, such as anxiety and depression, are a relevant co-morbidity in severe asthma. Anxiety and depression may also be common in the parents of asthmatic adolescents. The current study evaluated anxious and depressive symptoms in 40 adolescents suffering from severe asthma, and in their parents, before and after 1 year of treatment, tailored according to validated asthma guidelines. We used the HADS (Hospital Anxiety Depression Scale) questionnaire for the adolescents, and HADS, STAY (State-Trait Anxiety Inventory), and BDI (Beck Depression Inventory) questionnaires for their parents. We also considered the grade of asthma severity before and after 1 year of treatment. The current study demonstrated that anxiety and depression are common in both the adolescents suffering from severe asthma and their parents. Anxious and depressive symptoms were correlated between adolescents and their parents. Asthma treatment improved the asthma severity in almost all adolescents. However, the parental anxiety and depression remained unchanged at the end of the asthma treatment. Thus, a psychological assessment could be included in the adolescent severe asthma work-up, involving both the adolescents and their parents.

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Maternal anxiety and depression in pregnancy and DNA methylation of the NR3C1 glucocorticoid receptor gene

Epigenomics ◽

10.2217/epi-2020-0022 ◽

2020 ◽

Author(s):

Alexandra E Dereix ◽

Rachel Ledyard ◽

Allyson M Redhunt ◽

Tessa R Bloomquist ◽

Kasey JM Brennan ◽

...

Keyword(s):

Dna Methylation ◽

Depressive Symptoms ◽

Trait Anxiety ◽

Cpg Island ◽

Depression Scale ◽

Maternal Anxiety ◽

Anxiety And Depression ◽

Pregnancy Anxiety ◽

Glucocorticoid Receptor Gene ◽

Island Shore

Aim: To quantify associations of anxiety and depression during pregnancy with differential cord blood DNA methylation of the glucorticoid receptor ( NR3C1). Materials & methods: Pregnancy anxiety, trait anxiety and depressive symptoms were collected using the Pregnancy Related Anxiety Scale, State-Trait Anxiety Index and Edinburgh Postnatal Depression Scale, respectively. NR3C1 methylation was determined at four methylation sites. Results: DNA methylation of CpG 1 in the NR3C1 CpG island shore was higher in infants born to women with high pregnancy anxiety (β 2.54, 95% CI: 0.49–4.58) and trait anxiety (β 1.68, 95% CI: 0.14–3.22). No significant association was found between depressive symptoms and NR3C1 methylation. Conclusion: We found that maternal anxiety was associated with increased NR3C1 CpG island shore methylation.

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Cross-cultural measurement invariance of the Revised Child Anxiety and Depression Scale across 11 world-wide societies

Epidemiology and Psychiatric Sciences ◽

10.1017/s204579601600038x ◽

2016 ◽

Vol 26 (4) ◽

pp. 430-440 ◽

Cited By ~ 10

Author(s):

D. Stevanovic ◽

Z. Bagheri ◽

O. Atilola ◽

P. Vostanis ◽

D. Stupar ◽

...

Keyword(s):

Depressive Symptoms ◽

Ethnic Groups ◽

Measurement Invariance ◽

Factor Model ◽

Child Anxiety ◽

Depression Scale ◽

The Philippines ◽

Cross Cultural ◽

Health Study ◽

Anxiety And Depression

Background.In order to compare estimates by one assessment scale across various cultures/ethnic groups, an important aspect that needs to be demonstrated is that its construct across these groups is invariant when measured using a similar and simultaneous approach (i.e., demonstrated cross-cultural measurement invariance). One of the methods for evaluating measurement invariance is testing for differential item functioning (DIF), which assesses whether different groups respond differently to particular items. The aim of this study was to evaluate the cross-cultural measurement invariance of the Revised Child Anxiety and Depression Scale (RCADS) in societies with different socioeconomic, cultural, and religious backgrounds.Methods.The study was organised by the International Child Mental Health Study Group. Self-reported data were collected from adolescents residing in 11 countries: Brazil, Bulgaria, Croatia, Indonesia, Montenegro, Nigeria, Palestinian Territories, the Philippines, Portugal, Romania and Serbia. The multiple-indicators multiple-causes model was used to test the RCADS items for DIF across the countries.Results.Ten items exhibited DIF considering all cross-country comparisons. Only one or two items were flagged with DIF in the head-to-head comparisons, while there were three to five items flagged with DIF, when one country was compared with the others. Even with all cross-culturally non-invariant items removed from nine language versions tested, the original factor model representing six anxiety and depressive symptoms subscales was not significantly violated.Conclusions.There is clear evidence that relatively small number of the RCADS items is non-invariant, especially when comparing two different cultural/ethnic groups, which indicates on its sound cross-cultural validity and suitability for cross-cultural comparisons in adolescent anxiety and depressive symptoms.

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THE EFFECT OF DHIKR ON ANXIETY AND DEPRESSION LEVEL IN HEMODIALYSIS PATIENTS AT PURWOKERTO ISLAMIC HOSPITAL

International Journal of Islamic Medicine ◽

10.37275/ijim.v2i1.17 ◽

2021 ◽

Vol 2 (1) ◽

pp. 15-25

Author(s):

Muhammad Anggun ◽

Titik Kusumawinakhyu ◽

Irma Finurina Mustikawati ◽

Wiharto Wiharto

Keyword(s):

Intervention Group ◽

Depression Scale ◽

Sampling Technique ◽

Hemodialysis Patients ◽

Anxiety And Depression ◽

Control Group ◽

Control Group Design ◽

Hemodialysis Unit ◽

Before And After ◽

The Mean

Hemodialysis is a routinely performed therapy on chronic kidney patients, leading to psychological problems among subjects who undergo hemodialysis, such as anxiety and depression. One of the efforts to overcome anxiety and depression is with the dhikr intervention. Dhikr presents hearts to remember and be obedient to Allah followed by the words and actions in various conditions. Discover dhikr's influence on the level of anxiety and depression in patients on hemodialysis in Purwokerto Islamic Hospital. It was a quantitative study using quasi experiment with a non-quivalent control group design. The number of samples was 12 subjects consisting of 6 subjects in the control group and six subjects in the intervention group with the purposive sampling technique. Instruments were used to measure anxiety and depression are the HADS ( Hospital Anxiety and Depression Scale ) before and after dhikr intervention as much as 12 times. Research is carried out in Hemodialysis Unit of Purwokerto Islamic Hospital. Test statistics on research are used paired t-test and independent t-tests. This study showed a decrease in the mean level of anxiety from 5, 83 to 1.67 in the experimental group ( p = 0.003). The mean level of depression experienced a decline of 9, 67 becomes 4.67 on a group experiment ( p = 0.003). Dhikr reduces the level of anxiety and depression in hemodialysis patients at the Purwokerto Islamic Hospital.

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Improvement of Anxiety, Coughing, Breathlessness and Pain Control in The Management of Bronchoscopy by Adding Alprazolam

Jurnal Respirologi Indonesia ◽

10.36497/jri.v39i4.74 ◽

2019 ◽

Vol 39 (4) ◽

pp. 245-255

Author(s):

Yanny Octavia Sally Ride ◽

Yusup Subagio Sutanto ◽

Debree Septiawan

Keyword(s):

Lung Tumor ◽

Depression Scale ◽

Anxiety And Depression ◽

Control Group ◽

Control Group Design ◽

Before And After ◽

Post Test ◽

Vas Scores ◽

And Control ◽

Test Control

Background: Anxiolytic premedication can reduce anxiety, improving procedural tolerance, and reduce postbronchoscopic complications. There was ongoing debate about the safety of bronchoscopist-administered sedation. Alprazolam as a surgical premedication can reduce anxiety. Alprazolam can be used as an adjuvant analgesic, to reduce anxiety-related breathlessness, and to reduce coughing as adjuvant antitussive. The study aimed to evaluate the effectiveness of alprazolam in patients undergoing bronchoscopy. Methods: A clinical study with experimental quasi pre-post test control group design, using consecutive sampling was performed in patients with lung tumor undergoing bronchoscopy in dr.Moewardi Hospital from February to March 2019. The study subjects were divided in experimental (alprazolam) and control groups (without alprazolam). The Hospital Anxiety and Depression Scale (HADS), VAS for pain score, modified Borg score, and VAS for cough were measured in baseline, before, and after bronchoscopy. Results: Thirty two lung subjects were included in this study. The intervention groups showed decreased HADS score pre and post bronchoscopy (6.56±2.83 and 6.88±2.63), pain VAS scores (15.00±10.95 and 9.69±11.61), cough VAS score (11.56±8.89 and 27.19±17.89), and these were different significantly compared to control group. We found decreased mean of modified Borg in the study group though they were not significant compared to the control group. Conclusion: Alprazolam controlled anxiety, coughing, and pain in patients undergoing bronchoscopy. Alprazolam minimized breathlessness after bronchoscopy. (J Respir Indo. 2019; 39(4): 245-55)

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Prevalence and Influencing Factors of Anxiety and Depression Symptoms Amongst Surgical Nurses During COVID-19 Pandemic: A Large-Scale Cross-Sectional Study

10.21203/rs.3.rs-125116/v1 ◽

2020 ◽

Author(s):

Chun-Xia Ren ◽

De-Cun Zhou ◽

Yin-Guang Fan ◽

Bao-Zhu Li ◽

Wan-Fei Zhang ◽

...

Keyword(s):

Social Support ◽

Depressive Symptoms ◽

Influencing Factors ◽

Rating Scale ◽

Depression Scale ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Cross Sectional ◽

Self Rating ◽

Surgical Nurses

Abstract BackgroundThe outbreak of novel 2019 coronavirus disease (COVID-19) has imposed an enormous physical and psychological pressure on people across the world. This study focused on evaluating the prevalence and influencing factors of anxiety and depression symptoms in surgical nurses during the epidemic in China. MethodA cross-sectional, multicenter quantitative study was conducted in Anhui province (China) from March 3, 2020 to March 19, 2020, with a questionnaire package which consisted of general information questionnaire，Zung's self-rating anxiety scale (SAS), Zung's self-rating Depression Scale (SDS) and social support rating scale (SSRS). A total of 3600 surgical nurses participated in the survey by Wechat and QQ. Data were analysed using multiple linear regression models. ResultsA total of 3492 surgical nurses from 12tertiary hospitals and 12 secondary hospitals in one province of mainland China completed the survey. The prevalence rates of anxiety symptoms and depressive symptoms were 24.83% and 22.39%, respectively. The average level of anxiety and depression of surgical nurses were higher than that of the Chinese norm (P< 0.05).Levels of social support for surgical nurses were significantly negatively associated with the degree of anxiety (r = -0.630, P < 0.001) and depression (r = -0.578, P < 0.001). Fertility status (β = 1.469, P = 0.003), hospital (β = -0.611, P < 0.001), participation in care for COVID-19 patients (β = 2.229, P < 0.001), likelihood of being infected with COVID-19 (β = 1.146, P < 0.001), social support (β = -0.623, P < 0.001) were significantly influencing surgical nurses’ anxiety degree. Similarly, these characteristics were significantly associated with the odds of experiencing depression symptoms in surgical nurses. Divorce and widowed surgical nurses (β = -2.654, P < 0.001) were significantly more likely to experience depressive symptoms than single nurses. ConclusionIn this survey, we found that the surgical nurses had high anxiety and depression symptoms during the COVID-19 outbreak in China. The findings suggest that targeted psychological interventions to promote the mental health of surgical nurses with psychological problems need to be immediately implemented.

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Rates of Anxiety and Depressive Symptoms among Female Undergraduate Medical Students at National Medical College and Teaching Hospital

IRA-International Journal of Management & Social Sciences (ISSN 2455-2267) ◽

10.21013/jmss.v14.n2sp.p17 ◽

2019 ◽

pp. 171

Author(s):

Sandesh Sawant ◽

Garima Tripathi ◽

Tripti Pal Raman

Keyword(s):

Depressive Symptoms ◽

Medical Students ◽

Family History ◽

Depression Scale ◽

Anxiety Symptoms ◽

Drop Out ◽

Anxiety And Depression ◽

Female Undergraduate ◽

Undergraduate Medical Students ◽

The Mean

Background: Literature states that Depression and anxiety symptoms carry impairment to medical students, including poor academic performance, drop out, substance abuse and suicide. A high prevalence of anxiety and depression among medical students has been reported worldwide. Higher prevalence is noticed among female students.Aim/Objectives: To study rates of anxiety and depressive symptoms among female undergraduate medical students.Methods: The present study is a cross-sectional study. The purposive sampling method was used. Duration of study was 6 months. A total number of participants’ were 100. Self-developed questionnaire and Hospital Anxiety and Depression scale were used. Results: Findings showed that the mean score of anxiety symptoms was 8.08 (SD± 4.07). Similarly, the mean score of Depressive symptoms was 4.99(SD± 3.28). Fifty-two per cent of the students rated anxiety symptoms and 25% of the student rated depressive symptoms between borderline to the abnormal range. Total 9% of the students reported that they have a family history of mental illness among which 8% reported borderline to an abnormal range of anxiety however 52 % who had no family history also scored the same range. Similarly, 17% of the students reported there were life events which were stressful among which 13% scored borderline to abnormal range anxiety symptoms. Likewise, only 5% of the students scored borderline to the abnormal range of depressive symptoms.Conclusion: It was observed that female undergraduate medical students experience both anxiety and depressive symptoms however the percentage of depressive symptoms were less compared to anxiety symptoms. Further studies are required to evaluate the associated factors responsible for depressive and anxiety symptoms.

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A-121 Functional Outcomes in Bilingual Persons with Traumatic Brain: The Role of Mood

Archives of Clinical Neuropsychology ◽

10.1093/arclin/acab062.139 ◽

2021 ◽

Vol 36 (6) ◽

pp. 1171-1171

Author(s):

Winter Olmos ◽

Daniel W Lopez-Hernandez ◽

Isabel Munoz ◽

Laura Schierholz ◽

Rachel A Rugh-Fraser ◽

...

Keyword(s):

Depressive Symptoms ◽

Functional Outcomes ◽

Depression Scale ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Hospital Anxiety ◽

Anxiety Levels ◽

The Relationship ◽

Pearson Correlations

Abstract Introduction We examined the relationship between depression and anxiety, language, and functional outcomes in persons with traumatic brain injury (TBI). Methods The sample consisted of 48 acute TBI (ATBI: 23 Spanish-English Bilinguals; 25 English monolinguals), 30 chronic TBI (CTBI: 17 Spanish English Bilinguals; 12 English monolinguals), and 47 healthy comparison (HC: 29 Spanish-English Bilinguals; 18 English monolinguals) participants. The Hospital Anxiety and Depression Scale was used to measure depression (HADS-D) and anxiety (HADS-A). The Mayo Portland Adaptability Inventory-4 (MPAI-4) was used to measure functional outcomes (ability, adjustment, participation). Results An ANCOVA, controlling for age, revealed the ATBI group reported lower anxiety levels compared to the CTBI group, p = 0.034 np2 = 0.06. HC participants demonstrated significantly higher functional ability compared to both TBI groups, p < 0.05, np2 = 0.08–0.19. The ATBI group demonstrated worse participation scores compared to the CTBI and HC groups, p = 0.001, np2 = 0.11. Pearson correlations revealed mood was related to functional status in ATBI monolinguals (HADS-A: r = 0.29–0.64; HADS-D, r = 0.49–0.62). Monolingual participants with ATBI demonstrated correlations between depressive symptoms and functional adjustment (r = 0.57, p = 0.005) and ability (r = 0.44, p = 0.034). For monolinguals with CTBI, HADS-A correlated with functional outcomes, r = 0.60–0.66, p < 0.05. For bilinguals with CTBI, functional outcomes correlated with HADS-A, r = 0.53–0.66, p < 0.05, and HADS-D, r = 0.54–0.66, p < 0.05. For HC monolinguals, functional outcomes correlated with HADS-A, r = 0.53–0.70, p < 0.05, and HADS-D, r = 0.50–0.72, p < 0.05. Finally, for HC bilinguals, functional outcomes correlated with HADS-A, r = 0.59–0.68, p < 0.05. Conclusion Our results suggest that a relationship between anxiety and depressive symptoms is related more to functional outcomes in monolingual TBI survivors compared to bilingual TBI survivors.

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Use of digital game therapy among elderly persons undergoing dialytic treatment: cognitive aspects and depressive symptoms

Revista Brasileira de Geriatria e Gerontologia ◽

10.1590/1981-22562018021.170184 ◽

2018 ◽

Vol 21 (4) ◽

pp. 447-455

Author(s):

Sirlei Ricarte Bento ◽

Ana Carolina Ottaviani ◽

Allan Gustavo Brigola ◽

Vânia Paula de Almeida Neris ◽

Fabiana de Souza Orlandi ◽

...

Keyword(s):

Depressive Symptoms ◽

Depressive Symptom ◽

Intervention Program ◽

Depression Scale ◽

Elderly Persons ◽

Post Intervention ◽

Therapeutic Game ◽

Significant Difference ◽

Before And After ◽

The Mean

Abstract Objective :to evaluate the presence of depressive symptoms and cognitive disorders before and after an intervention program with a digital therapeutic game among elderly persons undergoing hemodialysis. Method: a quasi-experimental study was carried out with 26 elderly patients on hemodialysis. For the data collection, a questionnaire relating to sociodemographic and health conditions, the Geriatric Depression Scale - 15 items and Addenbrooke’s Cognitive Examination Revised were used. The intervention with the digital therapeutic game was performed over 5 sessions. Results: of the participants, 80.8% were male, with a mean age of 66.7 (± 5.8) years. The mean pre-intervention depressive symptom score was 3.9 (± 3.0) while post-intervention it was 2.8 (± 2.9), representing a statistically significant difference (p = 0.005). Regarding cognitive function, there was no statistically significant difference before and after the intervention. There was a statistically significant difference in the mean of the depressive symptom scores, which were lower after the intervention. In addition, there was no statistically significant difference in the mean of the cognitive assessments. Conclusion: intervention studies with patients undergoing hemodialysis treatment are still scarce and this study describes the positive results of an intervention with a digital therapeutic game, demonstrating improvement in the depressive symptoms of the participants.

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The COVID-19 Pandemic and Mental Well-Being of Pregnant Women in Japan: Need for Economic and Social Policy Interventions

Disaster Medicine and Public Health Preparedness ◽

10.1017/dmp.2020.334 ◽

2020 ◽

pp. 1-6 ◽

Cited By ~ 4

Author(s):

Midori Matsushima ◽

Hanna Horiguchi

Keyword(s):

Social Support ◽

Depressive Symptoms ◽

Pregnant Women ◽

Perceived Risk ◽

Depression Scale ◽

Well Being ◽

Anxiety And Depression ◽

Cutoff Score ◽

Economic Wealth ◽

Mental Well Being

ABSTRACT Objective: This study explores the mental well-being of pregnant women in Japan during the coronavirus disease (COVID-19) pandemic. Methods: We collected 1777 responses from pregnant women through an online survey. Using the Japanese version of the Edinburgh Postnatal Depression Scale (EPDS), we calculated the percentage of pregnant women above the cutoff (≥ 13), and the factor scores of anhedonia, anxiety, and depression. Regression analyses were performed to identify factors and socioeconomic characteristics correlated with depressive symptoms. Results: The point prevalence of pregnant women with an EPDS score of ≥ 13 was 17%. The mean scores were 0.73, 3.68, and 1.82 for anhedonia, anxiety, and depression, respectively. The probability of becoming above the cutoff score positively correlated with the cancellation of planned informal support, higher perceived risk for infection of COVID-19, difficulties in household finances, and lack of social support. Moreover, being younger, less wealthy, unemployed, and without a partner showed a significantly higher possibility of having a score above the cutoff. Conclusions: The present study found a high percentage of pregnant women with depressive symptoms. Notably, COVID-19-related variables, including perceived risk for the infection, fear of decreasing economic wealth, and social support, were significantly associated with depressive symptoms.

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Anxiety and depression in women hospitalized due to high-risk pregnancy: An integrative quantitative and qualitative study

Current Psychology ◽

10.1007/s12144-021-01902-5 ◽

2021 ◽

Author(s):

Martina Smorti ◽

Francesca Ginobbi ◽

Tommaso Simoncini ◽

Federica Pancetti ◽

Alessia Carducci ◽

...

Keyword(s):

Depressive Symptoms ◽

High Risk ◽

Risk Group ◽

Depression Scale ◽

High Risk Group ◽

Low Risk ◽

High Risk Pregnancy ◽

Anxiety And Depression ◽

Risk Pregnancy ◽

Low Risk Pregnancy

AbstractLiterature has shown that hospitalized women with high-risk pregnancy tend to develop anxious and depressive symptoms. Research has used quantitative or qualitative methods. By integrating both quantitative and qualitative methods, this study aims to analyze: a) the level of depression, anxiety, and pregnancy-related anxiety in a group of women hospitalized with high-risk pregnancy (hospitalized high-risk) compared with a group of non-hospitalized women with low-risk pregnancy; b) the content of hospitalization-related emotions in a high-risk group. A cross-sectional study was conducted on 30 hospitalized high-risk pregnant women and 32 women with low-risk pregnancy. Participants completed the Edinburgh Postnatal Depression Scale, Hospital Anxiety and Depression Scale (Anxiety), and Pregnancy Related Anxiety Questionnaire. The hospitalized high-risk group also completed open-ended questions about emotions experienced during hospitalization. Univariate Analysis of Covariance showed that the hospitalized high-risk group reported higher general anxiety and depression than the low-risk pregnancy group. Low-risk group reported higher level of concerns about own appearance than high-risk group. Narratives showed that the anxious and depressive symptoms of hospitalized women are related to the loneliness of being away from family. Despite attempts to understand hospitalization, they express concerns about pregnancy. Psychological support for hospitalized pregnant women should be provided to facilitate the communication of emotions that leads women to elaborate the experience of hospitalization to better adapt and cope with the critical condition.

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