Tailored Cigarette Warning Messages: How Individualized Loss Aversion and Delay Discounting Rates Can Influence Perceived Message Effectiveness

Current text-only cigarette warning labels (long-term, loss-framed messages) may not motivate positive changes in smoking behavior. The current project was a cross-sectional study examining the effects of tailored cigarette warnings on perceived message effectiveness (PME) in adult smokers (n = 512) conducted using Amazon Mechanical Turk (M-Turk) in January–February 2020. Participants were an average age of 40.7 (SD = 11.6), with the majority of the sample being female (62.2%) and White (88.9%). Participants reported smoking an average of 14.6 cigarettes/day (SD = 9.2) with an average FTND score of 4.6 (SD = 2.2). Participants were asked to complete a tobacco use history questionnaire, and mixed gambles and delay discounting tasks before random assignment to one of five message groups. The groups were based on a 2 (gain versus loss framing) ×2 (short-term versus long-term framing) between-subject design; a fifth group served as the control group. All experimental messages reported higher PME scores than the control (p values < 0.001, Cohen’s d = 1.88–2.48). Participants with shallower delayed reward discounting and lower loss aversion rates reported higher total PME scores, p values < 0.05. Our findings also suggest that loss aversion rates vary widely among smokers and that individuals are more responsive to messages congruent with their behavioral economic profile. Specifically, smokers who viewed messages congruent with their loss aversion and delay discounting rates reported higher PME scores than those who viewed incongruent messages (p = 0.04, Cohen’s d = 0.24). These preliminary findings suggest that anti-smoking campaigns may best impact smokers by tailoring messages based on individual loss aversion and delay discounting rates versus a one-size-fits-all approach.

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Effect of Long-Term Caloric Restriction on DNA Methylation Measures of Biological Aging in Healthy Adults: CALERIETM Trial Analysis

10.1101/2021.09.21.21263912 ◽

2021 ◽

Author(s):

reem waziry ◽

David L corcoran ◽

Kim M Huffman ◽

Michael S Kobor ◽

Meeraj Kothari ◽

...

Keyword(s):

Dna Methylation ◽

Controlled Trial ◽

Model Organisms ◽

Biological Aging ◽

Control Group ◽

Epigenetic Clock ◽

Long Term Effects ◽

Cohen’S D ◽

Cohen's D

Calorie restriction (CR) slows aging and increases healthy lifespan in model organisms. We tested if CR slowed biological aging in humans using DNA methylation analysis of blood samples from N=197 participants in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIETM) randomized controlled trial. We quantified CR effects on biological aging by comparing change scores for six epigenetic-clock and Pace-of-Aging measures between n=128 CR-group and n=69 ad-libitum-control-group participants at 12- and 24-month follow-ups. CR effects were strongest for DunedinPACE Pace of Aging (12-month Cohen's d=0.3; 24-month Cohen's d=0.2, p<0.01 for both), followed by DunedinPoAm and the GrimAge epigenetic clock, although effects for these measures were not statistically different from zero (p>0.08). CR effects for other epigenetic clocks were in the opposite direction (all p>0.15). CALERIE intervention slowed Pace of Aging but showed minimal effect on epigenetic clocks hypothesized to reflect longer term accumulation of aging burden.

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Lower Extremity Rehabilitation in Patients with Post-Stroke Sequelae through Virtual Reality Associated with Mirror Therapy

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18052654 ◽

2021 ◽

Vol 18 (5) ◽

pp. 2654

Author(s):

Roxana Steliana Miclaus ◽

Nadinne Roman ◽

Ramona Henter ◽

Silviu Caloian

Keyword(s):

Virtual Reality ◽

Muscle Strength ◽

Lower Extremity ◽

Range Of Motion ◽

Control Group ◽

Mirror Therapy ◽

Cohen’S D ◽

Cohen's D ◽

Experimental Group ◽

Post Therapy

More innovative technologies are used worldwide in patient’s rehabilitation after stroke, as it represents a significant cause of disability. The majority of the studies use a single type of therapy in therapeutic protocols. We aimed to identify if the association of virtual reality (VR) therapy and mirror therapy (MT) exercises have better outcomes in lower extremity rehabilitation in post-stroke patients compared to standard physiotherapy. Fifty-nine inpatients from 76 initially identified were included in the research. One experimental group (n = 31) received VR therapy and MT, while the control group (n = 28) received standard physiotherapy. Each group performed seventy minutes of therapy per day for ten days. Statistical analysis was performed with nonparametric tests. Wilcoxon Signed-Rank test showed that both groups registered significant differences between pre-and post-therapy clinical status for the range of motion and muscle strength (p < 0.001 and Cohen’s d between 0.324 and 0.645). Motor Fugl Meyer Lower Extremity Assessment also suggested significant differences pre-and post-therapy for both groups (p < 0.05 and Cohen’s d 0.254 for the control group and 0.685 for the experimental group). Mann-Whitney results suggested that VR and MT as a therapeutic intervention have better outcomes than standard physiotherapy in range of motion (p < 0.05, Cohen’s d 0.693), muscle strength (p < 0.05, Cohen’s d 0.924), lower extremity functionality (p < 0.05, Cohen’s d 0.984) and postural balance (p < 0.05, Cohen’s d 0.936). Our research suggests that VR therapy associated with MT may successfully substitute classic physiotherapy in lower extremity rehabilitation after stroke.

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Distance Motor Learning during the COVID-19 Induced Confinement: Video Feedback with a Pedagogical Activity Improves the Snatch Technique in Young Athletes

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18063069 ◽

2021 ◽

Vol 18 (6) ◽

pp. 3069

Author(s):

Mohamed Abdelkader Souissi ◽

Achraf Ammar ◽

Omar Trabelsi ◽

Jordan M. Glenn ◽

Omar Boukhris ◽

...

Keyword(s):

Retention Test ◽

Horizontal Displacement ◽

Test Session ◽

Video Feedback ◽

Control Group ◽

Maximum Height ◽

Kinematic Parameters ◽

School Aged Children ◽

Cohen’S D ◽

Cohen's D

The purpose of the present study was to investigate which of two strategies, Video Feedback with Pedagogical Activity (VF-PA) or Video Feedback (VF), would be more beneficial for the remote error correction of the snatch weightlifting technique during the confinement period. Thirty-five school aged children with at least three months of weightlifting experience were randomized to one of three training conditions: VF-PA, VF or the Control group (CONT). Subjects underwent test sessions one week before (T0) and one day after (T1) a six-session training period and a retention test session a week later (T2). During each test session, the Kinovea version 0.8.15 software measured the kinematic parameters of the snatch performance. Following distance learning sessions (T1), the VF-PA improved various kinematic parameters (i.e., barbell horizontal displacements, maximum height, looping and symmetry) compared with T0 (p < 0.5; Cohen’s d = 0.58–1.1). Most of these improvements were maintained during the retention test (T2) (p<0.01, Cohen’s d = 1.2–1.3) when compared withT0. However, the VF group improved only twoparameters (i.e., barbell symmetry and horizontal displacement) at T1 (p < 0.05; Cohen’s d = 0.9), which were not maintained at T2. Better horizontal displacement and looping values were registered during the retention test in the VF-PA group compared with theCONT group (p < 0.05, Cohen’s d = 1.49–1.52). The present findings suggest combining video feedback with pedagogical activity during the pandemic induced online coaching or physical education to improve movement learning in school aged children.

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Standardised cigarette packaging may reduce the implied safety of Natural American Spirit cigarettes

Tobacco Control ◽

10.1136/tobaccocontrol-2017-053940 ◽

2017 ◽

Vol 27 (e2) ◽

pp. e118-e123 ◽

Cited By ~ 9

Author(s):

Eric Craig Leas ◽

John P Pierce ◽

Claudiu V Dimofte ◽

Dennis R Trinidad ◽

David R Strong

Keyword(s):

Amazon Mechanical Turk ◽

Survey Experiment ◽

Plain Packaging ◽

Cohen’S D ◽

Brown Colour ◽

Graphic Image ◽

Cohen's D ◽

Erroneous Inferences ◽

Cigarette Package ◽

Item Scale

BackgroundOver two-thirds of Natural American Spirit (NAS) smokers believe their cigarettes might be ‘less harmful’, but toxicological evidence does not support this belief. We assessed whether standardised packaging could reduce the possibility of erroneous inferences of ‘safety’ drawn from NAS cigarette packaging.MethodsUS adult smokers (n=909) were recruited to a between-subject survey experiment (3 brands×3 packaging/labelling styles) through Amazon Mechanical Turk and rated their perception of whether a randomly assigned cigarette package conveyed that the brand was ‘safer’ on a three-item scale (Cronbach’s α=0.92). We assessed whether NAS packs were rated higher on the ‘implied safety’ scale than two other brands and estimated the effect that plain packaging (ie, all branding replaced with a drab dark brown colour) and Australian-like packaging (ie, all branding replaced with a drab dark brown colour and a graphic image and text on 75% of the pack surface) had on perceptions of the NAS cigarette package.ResultsSmokers’ ratings of the standard NAS pack on the implied safety scale (mean=4.6; SD=2.9) were 1.9 times (P <0.001) higher than smokers’ ratings of a Marlboro Red pack (mean=2.4; SD=2.3) and 1.7 times (P <0.001) higher than smokers’ ratings of a Newport Menthol pack (mean=2.7; SD=2.4). These perceptions of implied safety were lower when plain packaging was used (Cohen’s d=0.66; P <0.001) and much lower when Australian-like packaging was used (Cohen’s d=1.56; P <0.001).ConclusionThe results suggest that NAS cigarette packaging conveys that its cigarettes are ‘safer’ and that such perceptions are lower with standardised packaging, both with and without warning images.

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FINANCIAL MANAGEMENT SKILLS IN AGING, MCI AND DEMENTIA: CROSS SECTIONAL RELATIONSHIP TO 18F-FLORBETAPIR PET CORTICAL Β-AMYLOID DEPOSITION

Journal of Prevention of Alzheimer's Disease ◽

10.14283/jpad.2019.26 ◽

2019 ◽

pp. 1-9

Author(s):

S. Tolbert ◽

Y. Liu ◽

C. Hellegers ◽

J.R. Petrella ◽

M.W. Weiner ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

At Risk ◽

Amyloid Deposition ◽

Cross Sectional ◽

Cognitively Normal ◽

Financial Capacity ◽

Cohen’S D ◽

Β Amyloid ◽

Cohen's D

Background: There is a need to more fully characterize financial capacity losses in the preclinical and prodromal stages of Alzheimer’s disease (AD) and their pathological substrates. Objectives: To test the association between financial skills and cortical β-amyloid deposition in aging and subjects at risk for AD. Design: Cross-sectional analyses of data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI-3) study conducted across 50 plus sites in the US and Canada. Setting: Multicenter biomarker study. Participants: 243 subjects (144 cognitively normal, 79 mild cognitive impairment [MCI], 20 mild AD). Measurements: 18F-Florbetapir brain PET scans to measure global cortical β-amyloid deposition (SUVr) and the Financial Capacity Instrument Short Form (FCI-SF) to evaluate an individual’s financial skills in monetary calculation, financial concepts, checkbook/register usage, and bank statement usage. There are five sub scores and a total score (range of 0–74) with higher scores indicating better financial skill. Results: FCI-SF total score was significantly worse in MCI [Cohen’s d= 0.9 (95%CI: 0.6-1.2)] and AD subjects [Cohen’s d=3.1(CI: 2.5-3.7)] compared to normals. Domain scores and completion times also showed significant difference. Across all subjects, higher cortical β-amyloid SUVr was significantly associated with worse FCI-SF total score after co-varying for age, education, and cognitive score [Cohen’s f2=0.751(CI: 0.5-1.1)]. In cognitively normal subjects, after covarying for age, gender, and education, higher β -amyloid PET SUVr was associated with longer task completion time [Cohen’s f2=0.198(CI: 0.06-0.37)]. Conclusion: Using a multicenter study sample, we document that financial capacity is impaired in the prodromal and mild stages of AD and that such impairments are, in part, associated with the extent of cortical β-amyloid deposition. In normal aging, β-amyloid deposition is associated with slowing of financial tasks. These data confirm and extend prior research highlighting the utility of financial capacity assessments in at risk samples.

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Improving the Accuracy of Firearm Identification in a Dynamic Use of Force Scenario

Police Quarterly ◽

10.1177/1098611120944387 ◽

2020 ◽

pp. 109861112094438

Author(s):

M. Hunter Martaindale

Keyword(s):

Use Of Force ◽

Test Group ◽

Law Enforcement Officers ◽

Control Group ◽

Force Scenario ◽

Cohen’S D ◽

Cohen's D ◽

Speed And Accuracy ◽

Decision Errors ◽

Second Use

Law enforcement officers are sometimes required to make split-second use of force decisions. One factor that can impact their decision-making process is the presence of a weapon. This experiment sought to improve the speed and accuracy of weapon identification in a dynamic use of force scenario through the principles of deliberate practice. This research utilized randomized control trial with random assignment to either a control or test condition. Eighty-seven participants completed the pretest, intervention, and posttest. Participants’ vision was recorded via a mobile vision-tracker. With only 20 minutes of training, the test group made 1/3 the amount of decision errors as the control group (Cohen’s d = 0.95). The test group was about 16% faster than the control group at visually finding the object in the suspect’s hand and determining if it was a gun or not (Cohen’s d = 0.91).

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Long-term care for people with dementia: environmental design guidelines

International Psychogeriatrics ◽

10.1017/s1041610210000438 ◽

2010 ◽

Vol 22 (7) ◽

pp. 1084-1096 ◽

Cited By ~ 93

Author(s):

Richard Fleming ◽

Nitin Purandare

Keyword(s):

Long Term Care ◽

Survey Design ◽

Design Guidelines ◽

Sufficient Evidence ◽

Empirical Literature ◽

Control Group ◽

Cross Sectional ◽

Term Care ◽

People With Dementia

ABSTRACTBackground: A large and growing number of people with dementia are being cared for in long-term care. The empirical literature on the design of environments for people with dementia contains findings that can be helpful in the design of these environments. A schema developed by Marshall in 2001 provides a means of reviewing the literature against a set of recommendations. The aims of this paper are to assess the strength of the evidence for these recommendations and to identify those recommendations that could be used as the basis for guidelines to assist in the design of long term care facilities for people with dementia.Methods: The literature was searched for articles published after 1980, evaluating an intervention utilizing the physical environment, focused on the care of people with dementia and incorporating a control group, pre-test-post-test, cross sectional or survey design. A total of 156 articles were identified as relevant and subjected to an evaluation of their methodological strength. Of these, 57 articles were identified as being sufficiently strong to be reviewed.Results: Designers may confidently use unobtrusive safety measures; vary ambience, size and shape of spaces; provide single rooms; maximize visual access; and control levels of stimulation. There is less agreement on the usefulness of signage, homelikeness, provision for engagement in ordinary activities, small size and the provision of outside space.Conclusions: There is sufficient evidence available to come to a consensus on guiding principles for the design of long term environments for people with dementia.

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Latent cytomegalovirus infection does not influence long-term disease outcomes in Inflammatory Bowel Disease, but is associated with later onset of disease

10.21203/rs.2.13288/v1 ◽

2019 ◽

Author(s):

Kimberley van der Sloot ◽

Michiel D. Voskuil ◽

Marijn C. Visschedijk ◽

Eleonora A.M. Festen ◽

Hendrik M. van Dullemen ◽

...

Keyword(s):

Clinical Care ◽

Older Age ◽

Cmv Infection ◽

Level Of Evidence ◽

Cross Sectional ◽

P Values ◽

Disease Outcomes ◽

General Dutch Population ◽

Inflammatory Bowel

Abstract Background: Cytomegalovirus (CMV) infection is common in the general population. CMV infection negatively affects disease course in transplant recipients and HIV patients. Whereas primary CMV infections may occur sporadically in seronegative patients, all seropositive patients with inflammatory bowel syndrome (IBD) are at risk for CMV reactivation, due to the inflammatory mucosal and use of immunosuppressive medication. It’s unclear whether latent CMV infection, and risk of reactivations, influences long-term disease outcomes. In this study, we aim to explore whether CMV infection affects disease outcomes in IBD patients. Methods: We performed a cross-sectional cohort study with 1,404 patients with IBD from a single center. Clinical characteristics and disease outcomes were prospectively collected. We scrutinized CMV serology test results and performed additional CMV serology testing if serum was available. Results: Out of 699 IBD patients with CMV serology, 303 (43.3%) were seropositive, comparable to the general Dutch population. CMV seropositivity was associated with older age, longer IBD disease duration, non-Western origin, birth outside the Netherlands and a lower educational level (p-values≤0.004). CMV seropositivity was not associated with more complicated long-term disease outcomes of IBD (p-values>0.05). Seropositive patients presented with symptoms and were diagnosed at an older age compared to seronegative patients (p-values<0.01). Conclusions: CMV seropositivity does not influence disease outcomes of IBD patients and seems associated with a delay in IBD onset. Guidelines regarding CMV screening in patients with IBD are currently based on a low level of evidence. These data support the recommendation that routine CMV serology measurement isn’t necessary in the clinical care of IBD.

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Relationship between pediatric liquid medicines (PLMs) and dental caries in chronically ill children

Padjadjaran Journal of Dentistry ◽

10.24198/pjd.vol31no3.25071 ◽

2019 ◽

Vol 31 (3) ◽

pp. 167

Author(s):

Ankita Goyal ◽

Vatchala Rani ◽

Bhadravathi Cheluvaiah Manjunath ◽

Kanupriya Rathore

Keyword(s):

Dental Caries ◽

Statistical Tests ◽

Chronically Ill ◽

Cross Sectional Study ◽

Control Group ◽

P Value ◽

Cross Sectional ◽

Increased Risk ◽

Chronically Ill Children

Introduction: Purpose of this research is to assess the relationship between long-term pediatric liquid medicines (PLMs) consumption and dental caries in 2–12-years-old chronically ill children. Methods: A cross-sectional study was performed in a public pediatric hospital in India for a period of 6 months. A total of 455 children aged 2–12 years old with various chronic diseases who were receiving PLMs for more than 6 months were selected as the subjects in this study and compared with 531 children of similar age group and diseases who received other forms of medication. Dental caries was measured by DMFT/dmft and data collected were analyzed with SPSS (17th version) using statistical tests such as t-test and one-way ANOVA. Univariable logistic regression was used where the significance was fixed at a a p value of less than 0.001. Results: Children on PLMs had an increased risk of dental caries than those on other forms of medications (OR: 3.142, 95% CI: 2.37–4.15, p < 0.001). The prevalence of dental caries was higher (77.8%) in children consuming PLMs when compared to other forms of medication (52.7%). The mean DMFT and dmft scores were significantly higher in the study group when compared to the control group (p = 0.001). Conclusion: Long-term consumption of pediatric liquid medicines containing sucrose as a risk factor for dental caries among chronically ill children. sugar free options has to be used during prescription to prevent medication-triggered caries.Keywords: Paediatric liquid medicine, medication-triggered caries, sugar-free medication

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Efecto y satisfacción de un programa de actividad física controlada por pulsómetro en el índice de masa corporal de escolares con sobrepeso-obesidad (Effect of and satisfaction with a program of physical activity controlled through heart rate monitors on

Retos ◽

10.47197/retos.v0i33.58019 ◽

2017 ◽

pp. 179-184

Author(s):

Emilio J Martinez-López ◽

Jesús Moreno-Cerceda ◽

Sara Suarez-Manzano ◽

Alberto Ruiz-Ariza

Keyword(s):

Physical Activity ◽

Heart Rate ◽

Family Health ◽

The Body ◽

Control Group ◽

Heart Rate Monitor ◽

Sport Practice ◽

Cohen’S D ◽

Young Students ◽

Cohen's D

Sustituir el tiempo sedentario por la práctica sistemática de actividad física (AF) es uno de los grandes retos educativos y sociales dirigidos a jóvenes con sobrepeso-obesidad. El objetivo principal fue analizar el efecto en el índice de masa corporal (IMC) de un programa de AF extraescolar que empleó el pulsómetro como mecanismo para cuantificar el volumen e intensidad del ejercicio. Participaron 69 escolares con sobrepeso-obesidad de 9 a 12 años. La muestra se aleatorizó en grupo con programa y pulsómetro (GE1, n=23), grupo con solo programa (GE2, n=23), y grupo control que no realizó programa ni empleó pulsómetro (GC, n=23). Los resultados mostraron que GE1 había disminuido el IMC respecto al GC a los dos y tres meses de intervención (-1.65 kg/m2; p=.037, d de Cohen=.786; y -2.02 kg/m2, p=.006, d de Cohen=.895, respectivamente). GE1 incrementó significativamente el tiempo diario de intensidad máxima de AF medida por el pulsómetro (p=.028). El 86.9% y el 60.8% de los alumnos del GE1 y GE2 respectivamente afirmaron estar bastante o totalmente de acuerdo con el ítem “He comprobado que realizo más actividad física diaria que antes”. La mayoría de niños y padres del GE1 consideraron la experiencia como positiva y motivante para realizar más AF. Se concluye que un programa dirigido desde la Educación Física, que combina AF extraescolar y emplea el pulsómetro como mecanismo de control, disminuye el IMC en jóvenes con sobrepeso-obesidad después de dos meses de aplicación, aumenta la motivación por la práctica físico-deportiva, e implica cambios positivos en los hábitos de salud familiares. Abstract. Replacing sedentary time with systematic practice of PA is one of the major social and health challenges of globalized world. The main aim of this research was to analyze the effect of a program based on extracurricular PA, using heart rate monitor to quantify the volume and intensity of PA, on the body mass index (BMI). 69 young students with overweight-obesity aged nine to 12 years participated in this study. The sample was randomly split in two groups: PA program and heart rate monitor (EG1, n=23), PA program without heart rate monitor (EG2, n=23), and control group, whose members did not carry out any program nor used any heart rate monitor (CG, n=23). Results showed that GE1 decreased BMI more than CG after two and three months of intervention (-1.65 kg/m2; p=.037, Cohen’s d=.786; y -2.02 kg/m2, p=.006, Cohen’s d =.895, respectively). G1 significantly increased the daily time of PA at maximum intensity measured by the heart rate monitor (p=.028). 86.9% and 60.8% of students in EG1 and EG2 respectively, were quite or totally in agreement with the item "I have verified that I carry out more physical activity daily than before". The majority of children and parents in EG1 considered the experience as positive and motivating to practice more PA. A program focused on Physical Education and combining extracurricular PA and heart rate monitor as a control mechanism, decreases BMI in overweight-obese young students after two months of application, increases motivation towards PA and sport practice, and implies positive changes in family health habits.

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