scholarly journals Bionanofactories for Green Synthesis of Silver Nanoparticles: Toward Antimicrobial Applications

2021 ◽  
Vol 22 (21) ◽  
pp. 11993
Author(s):  
Ashvi Sanjay Jain ◽  
Pranita Subhash Pawar ◽  
Aira Sarkar ◽  
Vijayabhaskarreddy Junnuthula ◽  
Sathish Dyawanapelly

Among the various types of nanoparticles and their strategy for synthesis, the green synthesis of silver nanoparticles has gained much attention in the biomedical, cellular imaging, cosmetics, drug delivery, food, and agrochemical industries due to their unique physicochemical and biological properties. The green synthesis strategies incorporate the use of plant extracts, living organisms, or biomolecules as bioreducing and biocapping agents, also known as bionanofactories for the synthesis of nanoparticles. The use of green chemistry is ecofriendly, biocompatible, nontoxic, and cost-effective. We shed light on the recent advances in green synthesis and physicochemical properties of green silver nanoparticles by considering the outcomes from recent studies applying SEM, TEM, AFM, UV/Vis spectrophotometry, FTIR, and XRD techniques. Furthermore, we cover the antibacterial, antifungal, and antiparasitic activities of silver nanoparticles.

Author(s):  
Lavanya Krishnadhas ◽  
Santhi R. ◽  
Annapurani S.

Nanoparticles are gaining interest in biomedical applications due to its importance such as anti-bacterial, anti-fungal and anti-cancer agents. Conventional methods for the synthesis of metal nanoparticles involves toxic reagents which produce harmful by-products and are hazardous to the environment. To overcome these limitations, green synthesis of nanoparticles was established. Eco-friendly methods using plant extracts are gaining popularity due to the abundance of raw materials and the production of non-toxic by-products threatening to the environment. Moreover, the nanoparticles synthesized from the plant extract are cost-effective. In addition, nanoparticles produced by green synthesis methods produces synergetic effect where both the nanoparticles as well as the natural bioactive constituents of the plant influence the biocidal properties. Different methods namely heating in water bath, microwave oven and exposure to bright sunlight were adopted for the synthesis of silver nanoparticles. Plant extract based synthesis of silver nanoparticles was eco-friendly and shows an alternative promise in bio-medical applications and it undertakes the negative effects of synthetic drugs.


2021 ◽  
Vol 7 (2) ◽  
pp. 139 ◽  
Author(s):  
Mahendra Rai ◽  
Shital Bonde ◽  
Patrycja Golinska ◽  
Joanna Trzcińska-Wencel ◽  
Aniket Gade ◽  
...  

Nanotechnology is a new and developing branch that has revolutionized the world by its applications in various fields including medicine and agriculture. In nanotechnology, nanoparticles play an important role in diagnostics, drug delivery, and therapy. The synthesis of nanoparticles by fungi is a novel, cost-effective and eco-friendly approach. Among fungi, Fusarium spp. play an important role in the synthesis of nanoparticles and can be considered as a nanofactory for the fabrication of nanoparticles. The synthesis of silver nanoparticles (AgNPs) from Fusarium, its mechanism and applications are discussed in this review. The synthesis of nanoparticles from Fusarium is the biogenic and green approach. Fusaria are found to be a versatile biological system with the ability to synthesize nanoparticles extracellularly. Different species of Fusaria have the potential to synthesise nanoparticles. Among these, F. oxysporum has demonstrated a high potential for the synthesis of AgNPs. It is hypothesised that NADH-dependent nitrate reductase enzyme secreted by F. oxysporum is responsible for the reduction of aqueous silver ions into AgNPs. The toxicity of nanoparticles depends upon the shape, size, surface charge, and the concentration used. The nanoparticles synthesised by different species of Fusaria can be used in medicine and agriculture.


Author(s):  
Rohit Rajendra Bhosale ◽  
A S Kulkarni ◽  
S S Gilda ◽  
N H Aloorkar ◽  
R A Osmani ◽  
...  

Nanotechnology is an escalating field that has made its contribution to all spheres of human life. The green synthesis of nanoparticles has paved for better methodologies and approaches in the medicinal field. Nowadays silver, gold and other metallic nanoparticles are used as an efficient carrier for drug molecules for developing novel drug delivery systems. In course of synthesizing these nanoparticles various chemicals, solvents and reagents are used which harms our eco system directly or indirectly. Silver nanoparticles (Ag NPs) have been widely used as a novel therapeutic agent extending its use as antibacterial, antifungal, anti-viral and anti-inflammatory agent. Silver nanoparticles (Ag NPs) prepared by green synthesis have many advantages over conventional methods involving chemical agents associated with environmental toxicity. Green synthetic methods include polysaccharide method, irradiation method, biological method, polyoxometallates method and tollens method. Green synthesis of nanoparticles is found to be an emerging branch of nanotechnology. The use of environmentally benign materials like plant leaf extract for the synthesis of nanoparticles offers numerous benefits of eco-friendliness and compatibility for pharmaceutical and biomedical applications as they do not use toxic chemicals in the synthesis protocols. Rapid and green synthetic methods using various plant extracts have shown a great potential in silver nanoparticles (Ag NPs) synthesis. This review article describes the bio-inspired synthesis of nanoparticles that provides advancement over chemical and physical methods as it is cost effective, eco-friendly and more effective in a variety of applications.


2018 ◽  
Vol 81 (1) ◽  
Author(s):  
Adamu Ibrahim Usman ◽  
Azlan Abdul Aziz ◽  
Osama Abu Noqta

The field of nanotechnology is advancing rapidly due to its extensive applications in distinct fields of science and technology. Several methods have been used for the production of nanoparticles due to their immense functions in various fields. The limitations of the traditional methods and their toxic nature of the chemicals used during the synthesis or in their application hinder their usage in the biomedical field. This led to the development of the green synthesis of nanoparticles. Researchers have focused on developing simple, cost-effective, clean, non-toxic and eco-friendly procedures for synthesis of nanoparticles. Various biological agents like bacteria, fungi, plant extracts, etc. are used for the green synthesis of metal nanoparticles due to their biocompatibility. The dissolved metals ions are reduced into nano-metals by bio-agent in the green process. The manners and protocols of the green synthesis of gold nanoparticles are presented in this review. Recent literature on green synthesis of noble gold nanoparticles with their various applications in biomedical, antifungal/antibacterial, drug delivery, sensors and photocatalytic have also been discussed.


2015 ◽  
Vol 1109 ◽  
pp. 35-39 ◽  
Author(s):  
M.K. Nahar ◽  
Zarina Zakaria ◽  
U. Hashim ◽  
Md Fazlul Bari

The synthesis of nanoparticles is in the spotlight in modern nanotechnology. In recent years, the development of competent green chemistry methods for synthesis of metal nanoparticles (NPs) has become a main limelight of researchers. Biological synthesis of nanoparticles using plant extract is currently under exploitation. The first time in this paper we have reported the green synthesis of silver nanoparticles (AgNPs) by reduction of silver nitrate, using fruit extracts of Momordica charantia (bitter melon); commonly found plant in south East Asia. The reaction process for the synthesis of silver nanoparticles is simple, cost-effective, novel, rapid and eco-friendly route using fruit extract of M. charantia plant, which acted as a reducing and stabilizing agent simultaneously at room temperature. Formation of the nanosilver was confirmed by surface Plasmon spectra using UV-Vis spectrophotometer and absorbance peak at 440 nm. Different silver ion concentration and contact times were experimenting in the synthesis of silver nanoparticles. The prepared nanoparticles properties were characterized by UV-Vis.


2020 ◽  
Vol 9 (1) ◽  
pp. 268-274
Author(s):  
Anuja S. Kumar ◽  
Gayathri Madhu ◽  
Elza John ◽  
Shinoj Vengalathunadakal Kuttinarayanan ◽  
Saritha K. Nair

AbstractAmong the various green synthesis methods for nanoparticle synthesis, the honey-mediated green synthesis of nanoparticles is a fast, safe, biocompatible, and cost-effective method. In the present work, we demonstrate the sunlight-induced honey-mediated synthesis of silver nanoparticles and report the effect of light intensity, its color, and exposure time on the formation of nanoparticles. The visual inspection followed by UV-Vis spectral studies was performed to confirm the formation of silver nanoparticles. The HRTEM measurement confirms the formation of polydispersed silver particles. We further report the excellent antimicrobial activity of the synthesized nanoparticles against various strains of bacteria, which is found to be comparable to that of the antibiotic drug of choice. Our study points to further research on the possibility of considering these green synthesized silver nanoparticles as an alternative to antibiotics.


2020 ◽  
Vol 13 ◽  
Author(s):  
Kumari Jyoti ◽  
Punyasloka Pattnaik ◽  
Tej Singh

Background:: Synthesis of metallic nanoparticles has attracted extensive vitality in numerous research areas such as drug delivery, biomedicine, catalysis etc. where continuous efforts are being made by scientists and engineers to investigate new dimensions for both technological and industrial advancements. Amongst numerous metallic nanoparticles, silver nanoparticle (AgNPs) is a novel metal species with low toxicity, higher stability and significant chemical, physical and biological properties. Methods:: In this, various methods for the fabrication of AgNPs are summarized. Importantly, we concentrated on the role of reducing agents of different plants parts, various working conditions such as AgNO3 concentration; ratio of AgNO3/extract; incubation time; centrifugal conditions, size and shapes. Results:: This study suggested that eco-friendly and non toxic biomolecules present in the extracts (e.g. leaf, stem and root) of plants are used as reducing and capping agents for silver nanoparticles fabrication. This method of fabrication of silver nanoparticles using plants extracts is comparatively cost-effective and simple. A silver salt is simply reduced by biomolecules present in the extracts of these plants. In this review, we have emphasized the synthesis and antibacterial potential of silver nanoparticles using various plant extracts. Conclusion:: Fabrication of silver nanoparticles using plant extracts have advantage over the other physical methods, as it is safe, eco-friendly and simple to use. Plants have huge potential for the fabrication of silver nanoparticles of wide potential of applications with desired shape and size.


2021 ◽  
pp. 0958305X2198988
Author(s):  
Nur Syakirah Rabiha Rosman ◽  
Noor Aniza Harun ◽  
Izwandy Idris ◽  
Wan Iryani Wan Ismail

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.


2017 ◽  
Vol 6 (5) ◽  
Author(s):  
Zahra Abbasi ◽  
Sholeh Feizi ◽  
Elham Taghipour ◽  
Parinaz Ghadam

AbstractSilver nanoparticles (AgNPs) have widespread applications. Recently, the synthesis of NPs using plant extract has attracted much attention. In this study, with an easy and rapid process at room temperature, AgNPs were produced by the aqueous extract of dried


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Akshay Rajeev Geetha ◽  
Elizabeth George ◽  
Akshay Srinivasan ◽  
Jameel Shaik

Production of silver nanoparticles from the leaf extracts ofPimenta dioicais reported for the first time in this paper. Three different sets of leaves were utilized for the synthesis of nanoparticles—fresh, hot-air oven dried, and sun-dried. These nanoparticles were characterized using UV-Vis spectroscopy and AFM. The results were diverse in that different sizes were seen for different leaf conditions. Nanoparticles synthesized using sun-dried leaves (produced using a particular ratio (1 : 0.5) of the leaf extract sample and silver nitrate (1 mM), resp.) possessed the smallest sizes. We believe that further optimization of the current green-synthesis method would help in the production of monodispersed silver nanoparticles having great potential in treating several diseases.


Sign in / Sign up

Export Citation Format

Share Document