Green synthesis of silver nanoparticles using sustainable resources and their use as antibacterial agents: A review

2020 ◽  
Vol 13 ◽  
Author(s):  
Kumari Jyoti ◽  
Punyasloka Pattnaik ◽  
Tej Singh
Keyword(s):  
Silver Nanoparticles ◽  
Plant Extracts ◽  
Metallic Nanoparticles ◽  
Cost Effective ◽  
Biological Properties ◽  
Metal Species ◽  
Sustainable Resources ◽  
Research Areas ◽  
Low Toxicity

Background:: Synthesis of metallic nanoparticles has attracted extensive vitality in numerous research areas such as drug delivery, biomedicine, catalysis etc. where continuous efforts are being made by scientists and engineers to investigate new dimensions for both technological and industrial advancements. Amongst numerous metallic nanoparticles, silver nanoparticle (AgNPs) is a novel metal species with low toxicity, higher stability and significant chemical, physical and biological properties. Methods:: In this, various methods for the fabrication of AgNPs are summarized. Importantly, we concentrated on the role of reducing agents of different plants parts, various working conditions such as AgNO3 concentration; ratio of AgNO3/extract; incubation time; centrifugal conditions, size and shapes. Results:: This study suggested that eco-friendly and non toxic biomolecules present in the extracts (e.g. leaf, stem and root) of plants are used as reducing and capping agents for silver nanoparticles fabrication. This method of fabrication of silver nanoparticles using plants extracts is comparatively cost-effective and simple. A silver salt is simply reduced by biomolecules present in the extracts of these plants. In this review, we have emphasized the synthesis and antibacterial potential of silver nanoparticles using various plant extracts. Conclusion:: Fabrication of silver nanoparticles using plant extracts have advantage over the other physical methods, as it is safe, eco-friendly and simple to use. Plants have huge potential for the fabrication of silver nanoparticles of wide potential of applications with desired shape and size.

scholarly journals Silver Nanoparticles: Properties, Synthesis, Characterization, Applications and Future Trends

2021 ◽  
Author(s):  
Sunil T. Galatage ◽  
Aditya S. Hebalkar ◽  
Shradhey V. Dhobale ◽  
Omkar R. Mali ◽  
Pranav S. Kumbhar ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Metallic Nanoparticles ◽  
Large Scale ◽  
Cost Effective ◽  
Nano Particles ◽  
Scale Production ◽  
Green Technologies ◽  
Synthesis Of Nanoparticles ◽  
Vital Importance ◽  
Environmentally Safe

Nanotechnology is an expanding area of research where we use to deal with the materials in Nano-dimension. The conventional procedures for synthesizing metal nanoparticles need to sophisticated and costly instruments or high-priced chemicals. Moreover, the techniques may not be environmentally safe. Therefore “green” technologies for synthesis of nanoparticles are always preferred which is simple, convenient, eco-friendly and cost effective. Green synthesis of nanoparticle is a novel way to synthesis nanoparticles by using biological sources. It is gaining attention due to its cost effective, ecofriendly and large scale production possibilities. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. It has vital importance in nanoscience and naomedicines to treat and prevent vital disease in human beings especially in cancer treatment. In current work we discussed different methods for synthesis of AgNPs like biological, chemical and physical along with its characterization. We have also discussed vital importance of AgNPs to cure life threatnign diseases like cancer along with antidiabetic, antifungal, antiviral and antimicrobial alog with its molecular mode of action etc. Finally we conclude by discussing future prospects and possible applications of silver nano particles.

Biological Synthesis of Silver Nanoparticles and their Biomedical Activity: A Review

2021 ◽  
Vol 09 ◽  
Author(s):  
Sarvat Zafar ◽  
Aiman Zafar ◽  
Fakhra Jabeen ◽  
Miad Ali Siddiq
Keyword(s):  
Silver Nanoparticles ◽  
Large Scale ◽  
Scale Up ◽  
Cost Effective ◽  
Biological Properties ◽  
Single Step ◽  
Biological Synthesis ◽  
Nanosized Particles ◽  
Environment Friendly ◽  
Physical And Chemical

: Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors, like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particles exhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulant and catalytic properties because of their unique dimensions with large surface area, chemical stability and higher binding density for the accumulation of various bio-constituents on their surfaces. Biological approaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easy and single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physical and chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesis has drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy to scale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaboration of nanomaterials with bio-green approaches could extend the utilization of biological and cytological properties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, and their potential biomedical applications have also been reviewed.

Biological Synthesis of Nanosilver by Using Plants

2015 ◽  
Vol 1109 ◽  
pp. 30-34 ◽  
Author(s):  
M.K. Nahar ◽  
Zarina Zakaria ◽  
U. Hashim ◽  
Md Fazlul Bari
Keyword(s):  
Silver Nanoparticles ◽  
Green Chemistry ◽  
Metallic Nanoparticles ◽  
Large Scale ◽  
Cost Effective ◽  
High Energy ◽  
Vital Role ◽  
Environmentally Benign ◽  
Biological Synthesis ◽  
Promising Area

Nanotechnology is a most promising area that is increasing day by day and play a vital role in environments, biotechnological and biomedical fields. In recent years, the development of effective green chemistry methods for synthesis of various metal nanoparticles has become a main focus of researchers. They have investigated to find out a sustainable technique for production of well-characterized nanoparticles. A variety of chemical and physical methods have been exploited in the synthesis of silver nanoparticles (AgNPs) and these procedures remain expensive, high energy consumption and involve the use of hazardous chemicals. Therefore, there is an essential need to develop environmentally benign and sustainable procedures for synthesis of metallic nanoparticles. Increasing awareness of green chemistry and biological processes has need to develop a rapid, simple, cost-effective and eco-friendly methods. One of the most considered methods is production of nanosilver using plants and plant-derived materials which is the best candidates and suitable for large-scale biosynthesis of silver nanoparticles. Eco-friendly bio-organisms in plant extracts contain proteins, which act as both capping and reducing agents forming of stable and shape-controlled AgNPs. This review describes the recent advancements in the green synthesis of silver nanoparticles by using plants.

scholarly journals Environmentally benevolent synthesis and characterization of silver nanoparticles using Olea ferruginea Royle for antibacterial and antioxidant activities

2020 ◽  
Vol 9 (1) ◽  
pp. 451-461 ◽  
Author(s):  
Abid Hussain ◽  
Ansar Mehmood ◽  
Ghulam Murtaza ◽  
Khawaja Shafique Ahmad ◽  
Aneela Ulfat ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Antioxidant Activities ◽  
Cost Effective ◽  
Positive Control ◽  
Ag Nps ◽  
Stabilizing Agent ◽  
Mean Size ◽  
Spherical Crystals

AbstractIn this study, we reported an easy, rapid, cost-effective and environmentally benign method for the fabrication of silver nanoparticles (Ag-NPs) using Olea ferruginea as reducing, capping and stabilizing agent. For this, an aqueous extract of leaf and bark of O. ferruginea was treated with 1 mM AgNO3, which reduces Ag ions to Ag-NPs by establishing reddish brown color. The synthesized Ag-NPs were spherical crystals, with a mean size of 23 and 17 nm for leaf- and bark-mediated Ag-NPs, respectively. Fourier transform infrared spectroscopy affirmed the role of leaf and bark extracts of O. ferruginea as reducing, capping and stabilizing agent. These biosynthesized Ag-NPs showed profound antibacterial activity against Gram-negative (Pseudomonas aeruginosa and Escherichia coli) and Gram-positive (Streptococcus pneumonia and Staphylococcus aureus) bacteria. The highest antibacterial activity was shown by bark Ag-NPs against S. aureus (14.00 mm), while leaf Ag-NPs showed higher activity against S. pneumonia (13.00 mm). Additionally, they produced effective antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) as compared to plant extracts and positive control. It was observed that the bark-mediated Ag-NPs had higher percentage (90%) of scavenging potential than the leaf-mediated Ag-NPs (78%). The significance of the current study is the synthesis of eco-friendly, easy and cost-effective Ag-NPs as biomedical products.

scholarly journals All That Glitters Is Not Silver—A New Look at Microbiological and Medical Applications of Silver Nanoparticles

2021 ◽  
Vol 22 (2) ◽  
pp. 854
Author(s):  
Paweł Kowalczyk ◽  
Mateusz Szymczak ◽  
Magdalena Maciejewska ◽  
Łukasz Laskowski ◽  
Magdalena Laskowska ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Interdisciplinary Research ◽  
Biological Properties ◽  
Negative Effects ◽  
Growth And Survival ◽  
Animal Pathogens ◽  
Anti Cancer ◽  
Low Toxicity ◽  
Therapeutic Compounds ◽  
Legal Condition

Silver and its nanoparticles (AgNPs) have different faces, providing different applications. In recent years, the number of positive nanosilver applications has increased substantially. It has been proven that AgNPs inhibit the growth and survival of bacteria, including human and animal pathogens, as well as fungi, protozoa and arthropods. Silver nanoparticles are known from their antiviral and anti-cancer properties; however, they are also very popular in medical and pharmaceutical nanoengineering as carriers for precise delivery of therapeutic compounds, in the diagnostics of different diseases and in optics and chemistry, where they act as sensors, conductors and substrates for various syntheses. The activity of AgNPs has not been fully discovered; therefore, we need interdisciplinary research to fulfil this knowledge. New forms of products with silver will certainly find application in the future treatment of many complicated and difficult to treat diseases. There is still a lack of appropriate and precise legal condition regarding the circulation of nanomaterials and the rules governing their safety use. The relatively low toxicity, relative biocompatibility and selectivity of nanoparticle interaction combined with the unusual biological properties allow their use in animal production as well as in bioengineering and medicine. Despite a quite big knowledge on this topic, there is still a need to organize the data on AgNPs in relation to specific microorganisms such as bacteria, viruses or fungi. We decided to put this knowledge together and try to show positive and negative effects on prokaryotic and eukaryotic cells.

The Unprecedented Role of Gold Nanomaterial in Diabetes Management

2020 ◽  
Vol 13 (3) ◽  
pp. 219-227
Author(s):  
Simpal Kumari ◽  
Vipan Kumar Kamboj ◽  
Diksha Rajpoot ◽  
Anil Kumar Teotia ◽  
Prabhakar Kumar Verma ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Diabetes Management ◽  
High Surface ◽  
High Surface Area ◽  
Biological Properties ◽  
Low Toxicity ◽  
Gold Nanomaterial ◽  
Unique Potential ◽  
Delivery Approach

:Gold nanoparticles possess unique mechanical, chemical, photo-optical and biological properties and have been an interesting field of research on life sciences. The research studies produced new nanodevices and nanotechnology-based biosensing, diagnostics therapeutics, and targeted drug delivery systems. In this review, the unique potential aspects of gold nanoparticles/ nanoformulations/ or devices related to diabetes management have been discussed together with the recent patent on the gold nanoparticles developed for diabetes management. The first part of this review will focus on recent strategies for the treatment of hyperglycemia and its management with the help of gold nanoparticles and the second part of the review focused on recent patents on gold nanoparticles useful in the diabetes management. Gold nanoparticles have proved themselves useful in diabetes therapeutics and diagnostics. Due to the high surface area, and low toxicity, gold nanoparticles have become a unique aspect of the delivery approach. The main issues that need to be covered are the biopharmaceutics, biocompatibility, and potential clinical applications.

scholarly journals Transformation of Biowaste for Medical Applications: Incorporation of Biologically Derived Silver Nanoparticles as Antimicrobial Coating

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 229
Author(s):  
Sevakumaran Vigneswari ◽  
Tan Suet May Amelia ◽  
Mohamad Hazari Hazwan ◽  
Govindan Kothandaraman Mouriya ◽  
Kesaven Bhubalan ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antimicrobial Properties ◽  
Reduction Process ◽  
Cost Effective ◽  
Biological Properties ◽  
High Yield ◽  
Medical Sciences ◽  
Nanosized Materials ◽  
Methods Of Synthesis ◽  
Size And Morphology

Nanobiotechnology has undoubtedly influenced major breakthroughs in medical sciences. Application of nanosized materials has made it possible for researchers to investigate a broad spectrum of treatments for diseases with minimally invasive procedures. Silver nanoparticles (AgNPs) have been a subject of investigation for numerous applications in agriculture, water treatment, biosensors, textiles, and the food industry as well as in the medical field, mainly due to their antimicrobial properties and nanoparticle nature. In general, AgNPs are known for their superior physical, chemical, and biological properties. The properties of AgNPs differ based on their methods of synthesis and to date, the biological method has been preferred because it is rapid, nontoxic, and can produce well-defined size and morphology under optimized conditions. Nevertheless, the common issue concerning biological or biobased production is its sustainability. Researchers have employed various strategies in addressing this shortcoming, such as recently testing agricultural biowastes such as fruit peels for the synthesis of AgNPs. The use of biowastes is definitely cost-effective and eco-friendly; moreover, it has been reported that the reduction process is simple and rapid with reasonably high yield. This review aims to address the developments in using fruit- and vegetable-based biowastes for biologically producing AgNPs to be applied as antimicrobial coatings in biomedical applications.

scholarly journals Silver nanoparticles (AgNPs): as nanopesticides and nanofertilizers

2019 ◽  
Vol 4 (1) ◽  
pp. 19-20
Author(s):  
Rythem Anand ◽  
Madhulika Bhagat
Keyword(s):  
Silver Nanoparticles ◽  
Metallic Nanoparticles ◽  
Plant Disease ◽  
Agricultural Sector ◽  
Crop Protection ◽  
Cost Effective ◽  
Anticancer Properties ◽  
Agriculture Industry ◽  
Plant Disease Control ◽  
Important Field

Nanotechnology is evolving as an important field of sciences due to its promising role in the agricultural sector. Nanotechnology is being increasingly used to improve crop yield and reducing the harmful agents used in crop protection. Recently silver nanoparticles have gained utmost attention due its uses in various areas of human interest whether it be agriculture, industry, medicine and human health. They are the most popular metallic nanoparticles and its various antimicrobial and antioxidant as well as anticancer properties have been reported. This mini review aims to present and discuss development of cost effective techniques for the synthesis and recovery of silver nanoparticles that have agricultural importance. Many of its applications in plant disease control and other aspects such as their role as nanopesticides or nanofertilizers have been discussed.

scholarly journals Bionanofactories for Green Synthesis of Silver Nanoparticles: Toward Antimicrobial Applications

2021 ◽  
Vol 22 (21) ◽  
pp. 11993
Author(s):  
Ashvi Sanjay Jain ◽  
Pranita Subhash Pawar ◽  
Aira Sarkar ◽  
Vijayabhaskarreddy Junnuthula ◽  
Sathish Dyawanapelly
Keyword(s):  
Drug Delivery ◽  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Cost Effective ◽  
Biological Properties ◽  
Synthesis Of Nanoparticles ◽  
Physicochemical And Biological Properties ◽  
Living Organisms ◽  
Xrd Techniques ◽  
Shed Light

Among the various types of nanoparticles and their strategy for synthesis, the green synthesis of silver nanoparticles has gained much attention in the biomedical, cellular imaging, cosmetics, drug delivery, food, and agrochemical industries due to their unique physicochemical and biological properties. The green synthesis strategies incorporate the use of plant extracts, living organisms, or biomolecules as bioreducing and biocapping agents, also known as bionanofactories for the synthesis of nanoparticles. The use of green chemistry is ecofriendly, biocompatible, nontoxic, and cost-effective. We shed light on the recent advances in green synthesis and physicochemical properties of green silver nanoparticles by considering the outcomes from recent studies applying SEM, TEM, AFM, UV/Vis spectrophotometry, FTIR, and XRD techniques. Furthermore, we cover the antibacterial, antifungal, and antiparasitic activities of silver nanoparticles.

Innovative Eco-friendly Approaches for Green Synthesis of Silver Nanoparticles

2014 ◽  
Vol 7 (1) ◽  
pp. 2328-2337
Author(s):  
Rohit Rajendra Bhosale ◽  
A S Kulkarni ◽  
S S Gilda ◽  
N H Aloorkar ◽  
R A Osmani ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Metallic Nanoparticles ◽  
Human Life ◽  
Cost Effective ◽  
Synthetic Methods ◽  
Ag Nps ◽  
Synthesis Of Nanoparticles ◽  
Drug Molecules ◽  
Plant Leaf Extract

Nanotechnology is an escalating field that has made its contribution to all spheres of human life. The green synthesis of nanoparticles has paved for better methodologies and approaches in the medicinal field. Nowadays silver, gold and other metallic nanoparticles are used as an efficient carrier for drug molecules for developing novel drug delivery systems. In course of synthesizing these nanoparticles various chemicals, solvents and reagents are used which harms our eco system directly or indirectly. Silver nanoparticles (Ag NPs) have been widely used as a novel therapeutic agent extending its use as antibacterial, antifungal, anti-viral and anti-inflammatory agent. Silver nanoparticles (Ag NPs) prepared by green synthesis have many advantages over conventional methods involving chemical agents associated with environmental toxicity. Green synthetic methods include polysaccharide method, irradiation method, biological method, polyoxometallates method and tollens method. Green synthesis of nanoparticles is found to be an emerging branch of nanotechnology. The use of environmentally benign materials like plant leaf extract for the synthesis of nanoparticles offers numerous benefits of eco-friendliness and compatibility for pharmaceutical and biomedical applications as they do not use toxic chemicals in the synthesis protocols. Rapid and green synthetic methods using various plant extracts have shown a great potential in silver nanoparticles (Ag NPs) synthesis. This review article describes the bio-inspired synthesis of nanoparticles that provides advancement over chemical and physical methods as it is cost effective, eco-friendly and more effective in a variety of applications.

Sign in / Sign up

Export Citation Format

Share Document