scholarly journals Association of Whole Blood Fatty Acids and Growth in Southern Ghanaian Children 2–6 Years of Age

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 954 ◽  
Author(s):  
Mary Adjepong ◽  
William Yakah ◽  
William Harris ◽  
Esi Colecraft ◽  
Grace Marquis ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Growth Parameters ◽  
Dietary Fatty Acids ◽  
Northern Ghana ◽  
Z Score ◽  
Omega 3 ◽  
Omega 6 ◽  
Z Scores ◽  
Height For Age ◽  
Weight For Age

In Ghana, stunting rates in children below 5 years of age vary regionally. Dietary fatty acids (FAs) are crucial for linear growth. The objective of this study was to determine the association between blood FAs and growth parameters in southern Ghanaian children 2–6 years of age. A drop of blood was collected on an antioxidant treated card and analyzed for FA composition. Weight and height were measured and z-scores calculated. Relationships between FAs and growth were analyzed by linear regressions and factor analysis. Of the 209 subjects, 22% were stunted and 10.6% were essential FA deficient (triene/tetraene ratio > 0.02). Essential FA did not differ between stunted and non-stunted children and was not associated with height-for-age z-score or weight-for-age z-score. Similarly, no relationships between other blood fatty acids and growth parameters were observed in this population. However, when blood fatty acid levels in these children were compared to previously reported values from northern Ghana, the analysis showed that blood omega-3 FA levels were significantly higher and omega-6 FA levels lower in the southern Ghanaian children (p < 0.001). Fish and seafood consumption in this southern cohort was high and could account for the lower stunting rates observed in these children compared to other regions.

scholarly journals Composition of Dietary Fatty Acids and Health Risks in Japanese Youths

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 426
Author(s):  
Masayuki Okuda ◽  
Aya Fujiwara ◽  
Satoshi Sasaki
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Fatty Acids ◽  
High School Students ◽  
Junior High School ◽  
Compositional Data ◽  
Dietary Fatty Acids ◽  
Compositional Data Analysis ◽  
Omega 3 ◽  
Omega 6

In the overall composition of dietary fatty acids (FAs), the quantity of each FA is interrelated with that of others. We examined the associations between dietary FA composition and cardiometabolic risk in Japanese youths. Risk factors (anthropometric characteristics, serum lipid and liver enzyme levels, and blood pressure) were measured in 5485 junior-high-school students. Dietary intake was assessed using a food frequency questionnaire. The mean saturated FA (SFA), monounsaturated FA (MUFA), omega-6 polyunsaturated FAs (PUFAs), and omega-3 PUFAs intake were 9.6%E, 10.3%E, 6.3%E, and 1.1%E, respectively. In compositional regression analysis controlled for confounders, a high intake of omega-6 PUFAs relative to others was associated with low low-density-lipoprotein cholesterol levels (LDL-C; p = 0.003), and relative SFA intake was associated with high levels of gamma-glutamyl transpeptidase (p = 0.019). Relative omega-3 PUFAs intake was associated with low blood pressure (p = 0.005–0.034) but had unfavorable effects on adiposity and alanine transaminase. Substitutional models showed similar results for omega-6 PUFAs on LDL-C, but MUFA had inconsistent effects on risk factors. The results from the compositional data analysis were consistent with previous studies and clinical practice/knowledge. Focusing on increasing omega-6 PUFAs in Japanese youths could have favorable consequences in the long term.

scholarly journals Serum n-6 Fatty Acids are Positively Associated with Growth in 6-to-10-Year Old Ugandan Children Regardless of HIV Status—A Cross-Sectional Study

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1268 ◽  
Author(s):  
Raghav Jain ◽  
Amara E. Ezeamama ◽  
Alla Sikorskii ◽  
William Yakah ◽  
Sarah Zalwango ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Growth Parameters ◽  
Cross Sectional Study ◽  
Child Growth ◽  
Gas Chromatography Mass Spectrometry ◽  
Hiv Positive ◽  
Omega 3 ◽  
Hiv Status ◽  
Cross Sectional ◽  
Omega 6

Fatty acids (FAs) are crucial in child growth and development. In Uganda, antiretroviral therapy (ART) has drastically reduced perinatal human immunodeficiency virus (HIV) infection of infants, however, the interplay of FAs, ART, and HIV in relation to child growth is not well understood. To investigate this, serum was collected from 240 children between 6–10 years old in Uganda and analyzed for FAs using gas-chromatography mass-spectrometry. HIV status and anthropometric measurements were taken, and relationships with FAs were assessed. No significant differences in growth parameters or serum FAs were found between HIV uninfected children with and without exposure to ART. HIV positive children had significantly lower height-for-age-z-scores (HAZ) than uninfected children (p < 0.001). HIV-positive children had higher arachidonic acid than uninfected children (p = 0.003). Total omega-6 FAs were significantly associated with HAZ regardless of HIV status (p = 0.035). Mean total omega-3 FAs (2.90%) were low in this population compared to other cohorts in Africa. These results provide reference serum FA values for 6–10-year-old children in Uganda and may be used to inform lipid supplementation programs to promote child growth. Future studies should investigate the relationships between child growth trajectories in relation to HIV status and serum FAs.

scholarly journals Interaction between ω 6 and ω 3 fatty acids of different chain lengths regulates Atlantic salmon hepatic gene expression and muscle fatty acid profiles

2020 ◽  
Vol 375 (1804) ◽  
pp. 20190648 ◽  
Author(s):  
Mohamed Emam ◽  
Tomer Katan ◽  
Albert Caballero-Solares ◽  
Richard G. Taylor ◽  
Kathleen S. Parrish ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Atlantic Salmon ◽  
Quantitative Polymerase Chain Reaction ◽  
Dietary Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Omega 6 ◽  
Polymerase Chain ◽  
Positive Correlations ◽  
Chain Lengths

Atlantic salmon smolts (approx. 20-months old) were fed experimental diets with different combinations of omega-6:omega-3 fatty acids (FAs) (high-ω6, high-ω3, or balanced) and eicosapentaenoic acid plus docosahexaenoic acid (EPA + DHA) levels (0.3, 1.0 or 1.4%) for 12 weeks. Muscle FA (% total FA) reflected dietary C 18 -polyunsaturated FA; however, muscle EPA per cent and content (mg g −1 ) were not different in salmon fed high-ω3 or balanced diets. Muscle DHA per cent was similar among treatments, while DHA content increased in fish fed 1.4% EPA + DHA, compared with those fed 0.3–1.0% EPA + DHA combined with high-ω6 FA. Muscle 20:3 ω 6 (DGLA) content was highest in those fed high-ω6 with 0.3% EPA + DHA. Quantitative polymerase chain reaction analyses on liver RNA showed that the monounsaturated FA synthesis-related gene, scdb, was upregulated in fish fed 1.0% EPA + DHA with high-ω6 compared to those fed 0.3% EPA + DHA. In high-ω3-fed salmon, liver elovl2 transcript levels were higher with 0.3% EPA + DHA than with 1.0% EPA + DHA. In high-ω6-fed fish, elovl2 did not vary with EPA + DHA levels, but it was positively correlated with muscle ARA, 22:4 ω 3 and DGLA. These results suggest dietary 18:3 ω 3 elongation contributed to maintaining muscle EPA + DHA levels despite a two- to threefold change in dietary proportions, while 18:2 ω 6 with 0.3% EPA + DHA increased muscle DGLA more than arachidonic acid (ARA). Positive correlations between hepatic elovl2 and fabp10a with muscle ω 6: ω 3 and EPA + DHA + ARA, respectively, were confirmed by reanalysing data from a previous salmon trial with lower variations in dietary EPA + DHA and ω 6: ω 3 ratios. This article is part of the theme issue ‘The next horizons for lipids as ‘trophic biomarkers’: evidence and significance of consumer modification of dietary fatty acids’.

scholarly journals Development of LMS and Z Score Growth References for Egyptian Children From Birth Up to 5 Years

2021 ◽  
Vol 8 ◽  
Author(s):  
Ali M. El Shafie ◽  
Fady M. El-Gendy ◽  
Dalia M. Allahony ◽  
Hossam H. Hegran ◽  
Zein A. Omar ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Chronic Diseases ◽  
Child Growth ◽  
Z Score ◽  
Egyptian Children ◽  
Significant Difference ◽  
Z Scores ◽  
Growth References ◽  
Height For Age ◽  
Weight For Age

Background: The Lambda-Mu-Sigma (LMS) and Z score methods are important for assessment of growth and nutritional status. In Egypt, there is a lack of this tool for monitoring growth in preschool children.Objective: To develop LMS and Z score growth references for assessment of growth and nutritional status for Egyptian children from birth up to 5 years.Methods: A total of 27,537 children [13,888 boys (50.4%) and 13,649 girls (49.6%)] from birth up to 5 years were included in a multistage cross sectional randomized study from different Egyptian geographic districts to create LMS and Z score references for weight, length/height, and body mass index corresponding to age in addition to weight for length/height. Healthy term infants and children, exclusive breast feeding for at least 4 months and not suffering from any chronic diseases were included in this study. Children with dysmorphic features, preterm infants, admitted in neonatal or pediatric intensive care units and having any chronic diseases (hematological, cardiac, hepatic, and renal) were excluded. In addition any health condition that affects child growth including nutritional disorders was also excluded. Un-paired t-test was calculated to compare the means of weight for age, length/height for age, weight for length/height, and BMI for-age z scores of the Egyptian and WHO reference values.Results: Through detailed tables and graphs, LMS and Z scores for weight for age, length/height for age, weight for length/height, and BMI for age of both sexes were represented. Our findings showed no statistically significant difference between reference charts of WHO and Egyptian Z score charts (P &gt; 0.05).Conclusion: This study provides the first reference for Egyptian children from birth up to 5 years based on Z score tool for assessment the growth and nutritional status in various clinical conditions and research, also allows comparison with references of other countries.

scholarly journals Growth patterns in early childhood and the onset of menarche before age twelve

2010 ◽  
Vol 44 (2) ◽  
pp. 249-260 ◽  
Author(s):  
Jeovany Martínez ◽  
Cora Araújo ◽  
Bernardo Lessa Horta ◽  
Denise Petrucci Gigante
Keyword(s):  
Early Childhood ◽  
Rapid Growth ◽  
Multivariable Analysis ◽  
Overweight And Obesity ◽  
Growth Patterns ◽  
Z Score ◽  
Chi Square ◽  
Z Scores ◽  
Height For Age ◽  
Weight For Age

OBJECTIVE: To examine the relationship between growth patterns in early childhood and the onset of menarche before age 12. METHODS: The study included 2,083 women from a birth cohort study conducted in the city of Pelotas, Southern Brazil, starting in 1982. Anthropometric, behavioral, and pregnancy-related variables were collected through home interviews. Statistical analyses were performed using Pearson's chi-square and chi-square test for linear trends. A multivariable analysis was carried out using Poisson regression based on a hierarchical model. RESULTS: Mean age of menarche was 12.4 years old and the prevalence of menarche before age 12 was 24.3%. Higher weight-for-age, height-for-age, and weight-for-height z-scores at 19.4 and 43.1 months of age were associated with linear tendencies of increased prevalence and relative risks of the onset of menarche before age 12. Girls who experienced rapid growth in weight-for-age z-score from birth to 19.4 months of age and in weight-for-age or height-for-age z-scores from 19.4 to 43.1 months of age also showed higher risk of menarche before age 12. Higher risk was seen when rapid growth in weight-for-age z-score was seen during these age intervals and the highest risk was found among those in the first tertile of Williams' curve at birth. Rapid growth in weight-for-height z-score was not associated with menarche before age 12. CONCLUSIONS: Menarche is affected by nutritional status and growth patterns during early childhood. Preventing overweight and obesity during early childhood and keeping a "normal" growth pattern seem crucial for the prevention of health conditions during adulthood.

scholarly journals INFLUENCIA DE LOS ÁCIDOS GRASOS POLIINSATURADOS OMEGA-3 Y OMEGA-6 DE LA DIETA Y DE SUS METABOLITOS EN LA RESPUESTA INMUNE DE TIPO ALÉRGICO

2015 ◽  
Vol 63 (2) ◽  
pp. 301-313 ◽  
Author(s):  
DEIVIS JAVIER VILLANUEVA PÁJARO ◽  
JAVIER AVELINO MARRUGO CANO
Keyword(s):  
Fatty Acids ◽  
Allergic Inflammation ◽  
Public Health Problem ◽  
Allergic Diseases ◽  
Dietary Fatty Acids ◽  
Major Public Health Problem ◽  
Omega 3 ◽  
Palabras Clave ◽  
Omega 6 ◽  
Excessive Consumption

<p align="center"><strong>RESÚMEN</strong></p><p>Las tasas de prevalencia para las enfermedades alérgicas han experimentado un marcado incremento en los últimos cincuenta años, tanto en países desarrollados como en vías de desarrollo, en los cuales, dicho incremento está representado principalmente por la población de niños y adolescentes, un evento que a su vez se concibe como un problema relevante de salud pública mundial. Varios factores han sido propuestos tratando de explicar las causas de esta problemática, entre los que destaca la hipótesis de la dieta, señalando que componentes específicos de la alimentación y cambios en los patrones del mismo, propiciarían el desarrollo de las alergias e influirían en el incremento de su prevalencia. En apoyo de lo cual, la hipótesis de las grasas, expone que paralelo al aumento de las alergias a nivel global, ha existido también un consumo excesivo de alimentos con alto contenido de ácidos grasos omega-6 y bajos en omega-3, principalmente en dietas occidentales y como resultado de intervenciones en prevención del riesgo cardiovascular, lo que en conjunto pudiera explicar parte de este fenómeno mundial. El objetivo de la presente revisión temática es describir la influencia que ejercen algunos ácidos grasos poliinsaturados de las series omega-3 y omega-6 dietarios y de algunos de sus metabolitos en la respuesta inmune de tipo alérgico.</p><p><strong>Palabras Clave:</strong> Ácidos grasos dietarios, Ácidos grasos poliinsaturados omega-3 y omega-6, Hipótesis de la dieta, Hipótesis de las grasas, Enfermedades alérgicas, Inflamación alérgica.</p><p> </p><p align="center"><strong>INFLUENCE OF DIETARY POLYUNSATURATED OMEGA-3 AND OMEGA-6 FATTY ACIDS AND FROM ITS METABOLITES IN THE IMMUNE ALLERGIC RESPONSE</strong></p><p align="center"><strong> </strong></p><p align="center"><strong>ABSTRACT</strong></p><p>The rates of prevalence for allergic diseases have experienced a marked increase in the last fifty years, both in developed and developing countries, in which, such increase is mainly represented by the population of children and teens, an event which in turn is conceived as a major public health problem worldwide. Many factors have been proposed trying to explain the causes of this problematic, among which highlights the diet hypothesis, pointing that specific components of feeding and changes in the patterns of the same, would promote the development of allergies and will influence the increase from its prevalence. In support of which, the fat hypothesis, showing that parallel to the rise in allergies worldwide, also has been an excessive consumption of foods with high content of omega-6 fatty acids and low in omega-3, mainly in western diets and as result of interventions in cardiovascular risk prevention, which together could explain part of this global phenomenon. The objective of this thematic review is to describe the influence of some dietary polyunsaturated fatty acids of series omega-3 and omega-6 and several of its metabolites in the allergic immune response.</p><p><strong>Key Words: </strong>Dietary Fatty Acids, Polyunsaturated omega-3 and omega-6 fatty acids, Diet Hypothesis, Fat Hypothesis, Allergic Diseases, Allergic Inflammation.</p>

EFFECT OF GINGER, LEMURU FISH OIL SAPONIFICATION AND OLIVE OIL ON COMPOSITION FATTY ACID OF BEEF

2014 ◽  
Vol 4 (1) ◽  
pp. 31-39
Author(s):  
Siwitri Kadarsih
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Fish Oil ◽  
Olive Oil ◽  
Rice Bran ◽  
Dry Matter ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Omega 3 ◽  
Omega 6

The objective was to get beef that contain unsaturated fatty acids (especially omega 3 and 6), so as to improve intelligence, physical health for those who consume. The study design using CRD with 3 treatments, each treatment used 4 Bali cattle aged approximately 1.5 years. Observations were made 8 weeks. Pasta mixed with ginger provided konsentrat. P1 (control); P2 (6% saponification lemuru fish oil, olive oil 1%; rice bran: 37.30%; corn: 62.70%; KLK: 7%, ginger paste: 100 g); P3 (lemuru fish oil saponification 8%, 2% olive oil; rice bran; 37.30; corn: 62.70%; KLK: 7%, ginger paste: 200 g). Konsentrat given in the morning as much as 1% of the weight of the cattle based on dry matter, while the grass given a minimum of 10% of the weight of livestock observation variables include: fatty acid composition of meat. Data the analyzies qualitative. The results of the study showed that the composition of saturated fatty acids in meat decreased and an increase in unsaturated fatty acids, namely linoleic acid (omega 6) and linolenic acid (omega 3), and deikosapenta deikosaheksa acid.Keywords : 

scholarly journals Anti-Platelet Properties of Apple Must/Skin Yeasts and of Their Fermented Apple Cider Products

Beverages ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. 54
Author(s):  
Donal Moran ◽  
Mary Fleming ◽  
Eimear Daly ◽  
Natasha Gaughan ◽  
Ioannis Zabetakis ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Platelet Aggregation ◽  
Functional Properties ◽  
Human Platelet ◽  
Omega 3 ◽  
Apple Cider ◽  
Human Platelet Aggregation ◽  
Yeast Strains ◽  
Omega 6 ◽  
Anti Inflammatory

Alcoholic beverages like apple cider are considered functional beverages with several health benefits, when consumed in moderation, which are mainly attributed to their microbiota and the plethora of their bioactive compounds. Among them, bio-functional polar lipids (PL) have recently been found in apple cider, which despite low quantities, have exhibited strong anti-inflammatory and anti-platelet properties, while fermentation seems to affect the functionality of apple cider’s PL bioactives. The aim of the present study was to elaborate yeast strains isolated from the complex mixtures of apple surface and must yeasts for evaluating their effects on the anti-platelet functional properties of PL bioactives from their final fermented apple cider products. First, bio-functional PL were extracted and separated from the biomass of the different isolated apple surface/must yeast strains, and were further assessed for their anti-platelet potency against human platelet aggregation induced by the potent inflammatory and thrombotic mediator platelet-activating factor (PAF), or by a classic platelet agonist like adenosine diphopshate (ADP). Novel functional apple ciders were then produced from the fermentation of apple juice by elaborating the most bioactive and resilient yeast strains isolated from the apple must with optimum fermentation properties. PL bioactives extracted from these novel apple cider products were also further assessed for their anti-platelet properties against both the PAF and ADP pathways of human platelet aggregation. These novel cider products were found to contain PL bioactives with lower IC50 values (~40 μg) and thus increased anti-platelet potency against platelet aggregation induced by PAF and ADP. GC-MS analysis of the PL bioactives extracted from these novel apple ciders showed that apple cider PL bioactives are rich in monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), such as the omega-6 linoleic acid (LA) and the omega-3 alpha linolenic acid (ALA), with favorably lower levels for their omega-6/omega-3 PUFA ratio, which further support the observed strong anti-platelet properties putative anti-inflammatory potency for the apple cider PL bioactives. However, further studies are needed in order to elucidate and fully characterize the apple yeast strains that can be utilized for increasing the anti-inflammatory, anti-platelet and cardioprotective functional properties of their fermented apple cider products.

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