scholarly journals Plasma Phospholipid n-3/n-6 Polyunsaturated Fatty Acids and Desaturase Activities in Relation to Moderate-to-Vigorous Physical Activity through Pregnancy: A Longitudinal Study within the NICHD Fetal Growth Studies

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3544
Author(s):  
Liwei Chen ◽  
Yeyi Zhu ◽  
Zhe Fei ◽  
Stefanie N. Hinkle ◽  
Tong Xia ◽  
...  
Keyword(s):  
Physical Activity ◽  
Fatty Acids ◽  
Longitudinal Study ◽  
Fetal Growth ◽  
Desaturase Activity ◽  
Vigorous Physical Activity ◽  
Plasma Phospholipid ◽  
Late Pregnancy ◽  
Maternal Plasma ◽  
Dietary Factors

Maternal plasma phospholipid polyunsaturated fatty acids (PUFAs) play critical roles in maternal health and fetal development. Beyond dietary factors, maternal moderate-to-vigorous physical activity (MVPA) has been linked to multiple health benefits for both the mother and offspring, but studies investigating the influence of maternal MVPA on maternal PUFA profile are scarce. The objective of present study was to examine the time-specific and prospective associations of MVPA with plasma PUFA profile among pregnant women. This study included 321 participants from the National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies–Singletons cohort. Maternal plasma phospholipid PUFAs and MPVA were measured at four visits during pregnancy (10–14, 15–26, 23–31, and 33–39 gestational weeks (GW)). Associations of maternal MVPA with individual plasma PUFAs and desaturase activity were examined using generalized linear models. Maternal MVPA was associated inversely with plasma phospholipid linoleic acid, gamma-linolenic acid, and Δ6-desaturase in late pregnancy (23–31 or 33–39 GW), independent of maternal age, race, education, parity, pre-pregnancy body mass index, and dietary factors. Findings from this longitudinal study indicate that maternal habitual MVPA may play a role on PUFAs metabolism, particular by alerting plasma n-6 subclass and desaturase activity in late pregnancy. These associations are novel and merit confirmation in future studies.

scholarly journals Physical Activity and Plasma Phospholipid Saturated Fatty Acids During Pregnancy: A Longitudinal Study Within the NICHD Fetal Growth Studies

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1030-1030
Author(s):  
Xinyue Liu ◽  
Liwei Chen ◽  
Zhe Fei ◽  
Yeyi Zhu ◽  
Mengying Li ◽  
...  
Keyword(s):  
Physical Activity ◽  
Fatty Acids ◽  
Fetal Growth ◽  
Saturated Fatty Acids ◽  
Plasma Phospholipid ◽  
Healthy Eating Index ◽  
Repeated Measurements ◽  
Growth Studies ◽  
Modifiable Factors

Abstract Objectives Saturated fatty acids (SFAs), of both exogenous and endogenous origins, have been implicated in fetal development and pregnancy complications. Thus, it is essential to identify modifiable factors related to SFAs besides dietary intakes. Physical activity (PA) plays an important role in metabolism of SFAs, but the associations of PA with individual SFAs during pregnancy are unknown. The objective of this study is to examine the associations of PA with total and individual SFAs during pregnancy. Methods Study participants are 321 women from a nested case-control study for gestational diabetes mellitus within the prospective NICHD Fetal Growth Studies-Singletons (FGS). Individual plasma phospholipid SFAs were measured at the baseline (10–14 gestational weeks [GW]), and the follow-up visits (15–26, 23–31, and 33–39 GW). PA was assessed via the Pregnancy PA Questionnaire at each visit. The associations of total PA (metabolic equivalent hours per week) quartile with maternal phospholipid SFAs were estimated by linear regression models at baseline, and generalized estimation equations (GEEs) which account for repeated measurements at follow-up visits. Resampling weights were applied to represent the entire FGS. Models were adjusted for age, race, parity, education, marital status, smoking, alcohol use, mother born in US, pre-pregnancy Body Mass Index, and Healthy Eating Index. Results Cross the follow-up visits, compared to the lowest quartile of PA, women in the highest quartile had higher total SFAs (Q4 vs. Q1: β = 0.82; 95% CI: 0.12 to 1.52; P-trend: 0.02). When separated by even or odd-chain SFAs, the positive association was only observed between PA and even-chain SFAs (Q4 vs. Q1: β = 0.81; 95% CI: 0.12 to 1.50; P-trend: 0.03). No association was observed for individual SFAs cross the follow-up visits. Also, PA was not associated with SFAs at baseline. Conclusions Our finding suggested that PA is positively associated with the maternal even-chain SFAs of both endogenous and exogenous origins, but not with odd-chain SFAs in the second and third trimesters. This finding is novel and warrants the confirmation by future studies. Funding Sources Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)/National Institutes of Health (NIH).

scholarly journals A Longitudinal Study on Associations of Moderate-to-Vigorous Physical Activity With Plasma Monounsaturated Fatty Acids in Pregnant Women

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1299-1299
Author(s):  
Tong Xia ◽  
Liwei Chen ◽  
Zhe Fei ◽  
Xinyue Liu ◽  
Stefanie Hinkle ◽  
...  
Keyword(s):  
Physical Activity ◽  
Fatty Acids ◽  
Oleic Acid ◽  
Los Angeles ◽  
Pregnant Women ◽  
Leisure Time ◽  
Palmitoleic Acid ◽  
Vigorous Physical Activity ◽  
Plasma Phospholipid ◽  
Monounsaturated Fatty Acids

Abstract Objectives Maternal physical activity (PA) may influence pregnant women and offspring health via its impact on fatty acids metabolism. This study aimed to examine associations of PA with plasma phospholipid monounsaturated fatty acids (MUFAs) during pregnancy. Methods The study included 321 pregnant women from the NICHD Fetal Growth Studies (N = 2802) with plasma phospholipid MUFAs and PA measured four times at 10–14, 15–26, 23–31, and 33–39 gestational weeks (GWs). Leisure time moderate-to-vigorous PA (MVPA) was analyzed as both continuous (hour/week) and binary variables (i.e., high MVPA: ≥150 min/week vs. low MVPA: <150 min/week). Associations of MVPA with 7 individual plasma phospholipid MUFAs were assessed at each visit using multivariable linear regression models adjusting for age, race, education, marriage status, nulliparous, gestational diabetes, pre-pregnancy body mass index and Alternative Health Eating Index score. Weights were applied to reflect the entire cohort. Bonferroni-corrected P value < 0.05 was considered as statistically significant. Results MVPA (hour/week) was positively associated with plasma palmitoleic acid (β = 0.02, P < 0.001; N = 206) at 23–31 GW, and oleic acid (β = 0.08, P = 0.003; N = 308) at 15–26 GW. Meanwhile, compared to women with low level of MVPA, women with high level of MVPA had higher palmitoleic acid at 10–14 (β = 0.07, P = 0.001; N = 318) GW and 23–31 (β = 0.15, P < 0.001; N = 206) GW, and higher oleic acid (β = 0.40, P = 0.001; N = 308) at 15–26 GW. Conclusions We found positive associations of maternal MVPA with plasma palmitoleic acid and oleic acid at second trimester. Our findings are novel and worthy of further studies to confirm whether leisure time PA is a modifiable factor for MUFAs metabolism during pregnancy. Funding Sources Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)/National Institutes of Health (NIH); internal funding from University of California Los Angeles (UCLA).

scholarly journals The Effects of Physical Activity on Arterial Stiffness during Pregnancy: An Observational Study

2021 ◽  
Author(s):  
Brittany A Matenchuk ◽  
Katelyn Donna Fujii ◽  
Rachel J Skow ◽  
Frances M Sobierajski ◽  
Christina MacKay ◽  
...  
Keyword(s):  
Physical Activity ◽  
Arterial Stiffness ◽  
Vigorous Physical Activity ◽  
Late Pregnancy ◽  
Physical Activity Guidelines ◽  
Peripheral Pulse ◽  
Curvilinear Relationships ◽  
The Relationship ◽  
Carotid Artery Compliance ◽  
In Pregnancy

The objective of the present study was to investigate the relationship between moderate-to-vigorous physical activity (MVPA) and arterial stiffness in pregnancy. Thirty-nine women participated in this study resulting in 68 measurements in non-pregnant (NP; n=21), first (TM1; n=8), second (TM2; n=20), and third trimesters (TM3; n=19). Compliance, distensibility, elasticity, β-stiffness, and carotid to femoral (central) and carotid to finger (peripheral) pulse wave velocity (PWV) were assessed. MVPA was measured using accelerometry. Multilevel linear regressions adjusted for multiple tests per participant using random effects to generate β coefficients and 95% confidence intervals (CI) were performed. Distensibility, elasticity, β-stiffness, central- and peripheral-PWV did not differ between pregnant and non-pregnant assessments. Carotid artery compliance was higher in TM2 compared to NP. Central PWV (β Coef: -0.14, 95% CI: -0.27, -0.02) decreased from early to mid-pregnancy and increased in late pregnancy. Meeting the MVPA guidelines was significantly associated with central-PWV (Adj. β Coef: -0.34, 95% CI: -0.62, -0.06, p=0.016), peripheral-PWV (Adj. β Coef: -0.54, 95% CI: -0.91, -0.16, p=0.005), and distensibility (Adj. β Coef: -0.001, 95% CI: -0.002, -0.0001, p=0.018), in pregnancy. These results suggest that MVPA may be associated with improved (i.e. reduced) arterial stiffness in pregnancy. Novelty Bullets • Central PWV, distensibility, compliance, elasticity, and ß-stiffness, but not peripheral PWV, exhibited curvilinear relationships with gestational age • Central and peripheral PWV were lower in pregnant women who met the physical activity guidelines of 150 minutes of moderate-to-vigorous physical activity per week

scholarly journals ASUPAN LEMAK, AKTIVITAS FISIK DAN KEGEMUKAN PADA REMAJA PUTRI DI SMP BINA INSANI SURABAYA

2018 ◽  
Vol 13 (2) ◽  
pp. 117
Author(s):  
Jayanti Ayu Praditasari ◽  
Sri Sumarmik
Keyword(s):  
Physical Activity ◽  
High School ◽  
Fatty Acids ◽  
Adolescent Girls ◽  
Junior High School ◽  
Junior High ◽  
Saturated Fatty Acids ◽  
Monounsaturated Fatty Acids ◽  
Dietary Factors ◽  
Fat Intake

Obesity is defi ned as excessive fat accumulation fat that causes excess weight. Diseases that related with obesity are diabetes, dyslipidemia, hypertension and other degenerative diseases. Factors that affect obesity are dietary factors,history of hereditary, lifestyle, psychological factors, environment, individual, and biological which may infl uence energy intake and expenditure. Consumption of high fat in a long period without any activity for energy expenditure can increase the risk of obesity. This study was aimed to analyse the correlation between fat intake and physical activity with obesity among adolescent girls in SMP Bina Insani junior high school Surabaya. This study employed a case control study design with a retrospective approach. The research participants were 32 female students in Bina Insani junior high school Surabaya (16 control and 16 case samples). Total fat intake was relatively low. The intake of Monounsaturated Fatty Acids (MUFA) and Polyunsaturated Fatty Acids (PUFA) were low while Saturated Fatty Acids (SFA) were high. There was no correlation between fat intake and obesity (ρ=0.240), but there was a signifi cant correlation between physical activity ρ=0.006 (OR= 9.533, 95% CI: 1.847-49.204) with adolescent obesity. The very mild physical activity give a risk as much as 9.533 times greater for developing obesity than the mild physical.Therefore, it is necessary to increase physical activity among adolescent girls by doing sports to reduce the risk of obesity.

Geographic variations and determinants of EPA plus DHA and EPA alone in pregnant and lactating women from China

2021 ◽  
pp. 1-32
Author(s):  
Shaohua Yin ◽  
Yubo Zhou ◽  
Hongtian Li ◽  
Ying Meng ◽  
Jianmeng Liu
Keyword(s):  
Fatty Acids ◽  
Family Income ◽  
Late Pregnancy ◽  
Epidemiological Data ◽  
Maternal Plasma ◽  
Geographic Variations ◽  
Lactating Women ◽  
Maternal Characteristics ◽  
Total Fatty Acids ◽  
Geographic Regions

Abstract Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are essential for maternal and fetal health, but epidemiological data is sparse in China. We examined the trends of EPA alone and a combination of EPA plus DHA in pregnant and lactating women in three distinct geographic regions in China, and explored their potential influencing factors. A total of 1015 healthy women during mid-pregnancy, late pregnancy, or lactation were recruited from Weihai (coastland), Yueyang (lakeland), and Baotou (inland) cities of China between May and July of 2014. Maternal EPA and DHA concentrations (percentage of total fatty acids) in plasma and erythrocytes were measured by capillary gas chromatography. Adjusted EPA plus DHA concentrations in both plasma and erythrocytes significantly declined from mid-pregnancy (2.92%,6.95%), to late pregnancy (2.20%,6.42%) and lactation (2.40%,6.29%) (Ptrend<0.001); and both concentrations were highest in coastland, followed by lakeland, and lowest in inland (P<0.001). Regarding EPA alone, the concentrations were higher in women during lactation or late pregnancy and in women in coastland and inland areas. Moreover, concentrations of EPA or EPA plus DHA were higher in women with older age, higher education, higher annual family income per capita, and higher dietary intake of marine aquatic product and mutton. In lactating women, erythrocyte EPA concentration was higher in those having breastfeeding partially versus exclusively. In conclusion, maternal plasma and erythrocyte concentrations of EPA plus DHA or EPA alone differed with geographic regions, physiological periods and maternal characteristics, indicating a need of population-specific health strategies to improve fatty acids status in pregnant and lactating women.

scholarly journals BMI-specific associations between health-related behaviours and overweight – a longitudinal study among Norwegian adolescents

2016 ◽  
Vol 20 (3) ◽  
pp. 481-491 ◽  
Author(s):  
Inger M Oellingrath ◽  
Martin V Svendsen
Keyword(s):  
Physical Activity ◽  
Longitudinal Study ◽  
Early Adolescence ◽  
Screen Time ◽  
Vigorous Physical Activity ◽  
Principal Component ◽  
Eating Patterns ◽  
Eating Pattern ◽  
10Th Grade ◽  
Health Related

AbstractObjectiveTo investigate BMI-specific associations between health-related behaviours in early adolescence and the likelihood of overweight in mid-adolescence in a sample of Norwegian adolescents.DesignLongitudinal study of 393 adolescents recruited from schools in Telemark County, Norway. Parents reported baseline data on children’s behavioural variables and background data (at age 12–13 years). Dietary data were reported by means of a retrospective FFQ. Eating patterns were identified using principal component analysis. Height and weight were measured at baseline and 3-year follow-up. BMI-specific differences in health-related behaviours (eating patterns, physical activity and screen time) at baseline were analysed using cross-tabulation and Pearson’s χ2 test (Fisher’s test). Associations between early health-related behaviours and the likelihood of later overweight were examined using multiple logistic regression.SettingPrimary and secondary schools, Telemark, Norway.SubjectsChildren (n 393) in 7th grade (mean age 12·7 (sd 0·3) years), followed up in 10th grade, and parents.ResultsA moderate to high intake of a varied Norwegian eating pattern combined with moderate-to-vigorous physical activity ≥1 h/d in the 7th grade were associated with a reduced likelihood of being overweight in the 10th grade, but only among already overweight adolescents (adjusted OR=0·2; 95 % CI 0·1, 1·0). Screen time of >3 h/d in the 7th grade was associated with an increased likelihood of subsequent overweight only among adolescents with an initial normal weight (adjusted OR=2·8; 95 % CI 1·1, 7·3).ConclusionsBMI-specific associations were observed between health-related behaviours in early adolescence and the likelihood of being overweight in mid-adolescence.

scholarly journals Lifestyle changes associated with participation in colorectal cancer screening: Prospective data from the English Longitudinal Study of Ageing

2018 ◽  
Vol 26 (2) ◽  
pp. 84-91 ◽  
Author(s):  
Claire Stevens ◽  
Samuel G Smith ◽  
Charlotte Vrinten ◽  
Jo Waller ◽  
Rebecca J Beeken
Keyword(s):  
Physical Activity ◽  
Longitudinal Study ◽  
Cancer Screening ◽  
Vegetable Consumption ◽  
Vigorous Physical Activity ◽  
Health Behaviours ◽  
Fruit And Vegetable Consumption ◽  
Teachable Moment ◽  
Fruit And Vegetable ◽  
English Longitudinal Study

Objectives Population-based cancer screening has been described as a teachable moment for behaviour change. This research examined the effect of faecal occult blood testing (FOBT) participation on smoking, alcohol consumption, fruit and vegetable consumption and physical activity. Setting Data were from screening-naïve men within the English Longitudinal Study of Ageing, receiving their first FOBT invitation (n = 774). Four waves of data were included in analyses (wave 4, 2008/2009 – wave 7, 2014/2015). Baseline data were from the wave prior to FOBT invitation, and follow-up data were from the next consecutive wave (two years later). Methods The effects of FOBT participation, time and group-by-time interactions on health behaviours were investigated using generalised estimating equations. Almost two-thirds of the sample (62.5%; n = 484) had participated in FOBT. Results Screening participants were less likely to smoke (odds ratio (OR): 0.45, 95% confidence interval (CI): 0.29–0.68) and more likely to meet fruit and vegetable consumption guidelines (OR: 1.70, 95% CI: 1.14–2.55). Smoking decreased over time (OR: 0.74, 95% CI: 0.62–0.89), but adherence to alcohol guidelines also decreased (OR: 0.71, 95% CI: 0.53–0.91). A group-by-time interaction was found for vigorous physical activity; the odds of taking part in vigorous physical activity increased for FOBT participants, but decreased for non-participants (OR: 1.40, 95% CI: 1.01–1.95). Conclusions This research provides tentative support for FOBT as a teachable moment for increasing vigorous physical activity. However, overall, there was limited evidence for spontaneous improvement in multiple health behaviours following participation.

scholarly journals Vegetable and fruit consumption associated with anthropometric, dietary and lifestyle factors in Spain

1999 ◽  
Vol 2 (3) ◽  
pp. 263-271 ◽  
Author(s):  
Antonio Agudo ◽  
Guillem Pera ◽  
Keyword(s):  
Physical Activity ◽  
Fatty Acids ◽  
Unsaturated Fatty Acids ◽  
Vegetable Intake ◽  
Saturated Fatty Acids ◽  
Dietary Factors ◽  
Fruit Intake ◽  
Cross Sectional ◽  
Lineal Regression ◽  
Sectional Analysis

AbstractObjectiveTo evaluate the association of vegetable and fruit intake with several demographic, anthropometric, lifestyle and dietary factors.Design and settingCross-sectional analysis. Information on habitual diet was collected by means of the diet history method. Association of vegetable and fruit intakes with other factors was assessed separately by means of multiple lineal regression and the cumulative odds model.Subjects39 622 healthy subjects aged 29–69 years from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort in Spain.ResultsFruit intake increased with age, education and physical activity and decreased with intake of saturated fatty acids and cholesterol; smoking and alcohol consumption were also negatively associated with fruit, with a very low consumption for current smokers and heavy drinkers. Vegetable intake increased with education and physical activity and with intake of unsaturated fatty acids, mainly mono-unsaturated. Former smokers consumed more vegetables than never or current smokers and non-consumers of alcohol ate less vegetables than consumers, among whom no differences were observed. All these estimates were adjusted by energy and body mass index (BMI).ConclusionsWhen assessing the association of fruit and vegetables with chronic diseases it is important to take into account confounding factors. Furthermore, it would be useful to study dietary patterns including several interrelated factors.

Changes in Aerobic Fitness in Boys and Girls Over a Period of 25 Years: Data From the Amsterdam Growth and Health Longitudinal Study Revisited and Extended

2013 ◽  
Vol 25 (4) ◽  
pp. 524-535 ◽  
Author(s):  
Han C.G. Kemper ◽  
Jos W.R. Twisk ◽  
Willem van Mechelen
Keyword(s):  
Physical Activity ◽  
Longitudinal Study ◽  
Aerobic Fitness ◽  
Generalized Estimating Equations ◽  
Growth And Development ◽  
Longitudinal Design ◽  
Vigorous Physical Activity ◽  
Peak Oxygen Uptake ◽  
Repeated Measurements ◽  
Age Range

In the Amsterdam Growth And Health Longitudinal Study (AGAHLS), a group of approximately 650 12- to 14-year-old boys and girls was followed in their growth, and development of their health their lifestyle including diet, physical activity and smoking. One of the main interests was the change in their aerobic fitness. From 12 to 36 years of age in total, eight repeated measurements were performed to measure peak oxygen uptake (peak VO2). In this study the data of peak VO2 are revisited and extended: We made use of all collected data as a mixed longitudinal design including cross-sectionally measured subjects as well as longitudinally measured subjects. This led to the availability of 1,194 boys and 1356 girls. With generalized estimating equations (GEE) the longitudinal changes with chronological age and differences between boys and girls were analyzed. Teenage boys and girls increased their peak VO2 (ml/min) significantly (p < .001) until age 14 in girls and until age 17 in boys. However peak VO2 relative to bodyweight (peak VO2/BW) had significantly (p < .001) decreased over the whole age range from 12 to 36 in both sexes. Vigorous physical activity (VPA) also showed a decrease and was significantly (p < .001) related with lower peak VO2/BW (Beta = 0.001). This relation was stronger in boys than in girls. Because at the start of AGAHLS no fast responding metabolic instruments were available, future longitudinal studies about aerobic fitness should include also measurement of VO2 kinetics.

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