scholarly journals The Window Matters: A Systematic Review of Time Restricted Eating Strategies in Relation to Cortisol and Melatonin Secretion

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2525
Author(s):  
Shreya Chawla ◽  
Spyridon Beretoulis ◽  
Aaron Deere ◽  
Dina Radenkovic
Keyword(s):  
Circadian Rhythm ◽  
Food Intake ◽  
Inclusion Criteria ◽  
Eating Pattern ◽  
Ramadan Fasting ◽  
Breakfast Skipping ◽  
Metabolic Outcomes ◽  
Daily Food ◽  
Morning Cortisol ◽  
Contrasting Effect

Time-Restricted Eating is an eating pattern based on the circadian rhythm which limits daily food intake (usually to ≤12 h/day), unique in that no overt restriction is imposed on the quality, nor quantity, of food intake. This paper aimed to examine the effects of two patterns of TRE, traditional TRE, and Ramadan fasting, on two markers of circadian rhythm, cortisol and melatonin. PubMed and Web of Science were searched up to December 2020 for studies examining the effects of time restricted eating on cortisol and melatonin. Fourteen studies met our inclusion criteria. All Ramadan papers found statistically significant decrease in melatonin (p < 0.05) during Ramadan. Two out of the three Ramadan papers noted an abolishing of the circadian rhythm of cortisol (p < 0.05). The non-Ramadan TRE papers did not examine melatonin, and cortisol changes were mixed. In studies comparing TRE to control diets, Stratton et al. found increased cortisol levels in the non-TRE fasting group (p = 0.0018) and McAllister et al. noted no difference. Dinner-skipping resulted in significantly reduced evening cortisol and non-significantly raised morning cortisol. Conversely, breakfast skipping resulted in significantly reduced morning cortisol. This blunting indicates a dysfunctional HPA axis, and may be associated with poor cardio-metabolic outcomes. There is a paucity of research examining the effects of TRE on cortisol and melatonin. The contrasting effect of dinner and breakfast-skipping should be further examined to ascertain whether timing the feeding window indeed has an impact on circadian rhythmicity.

scholarly journals Association between breakfast skipping and metabolic outcomes by sex, age, and work status stratification

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jun Heo ◽  
Won-Jun Choi ◽  
Seunghon Ham ◽  
Seong-Kyu Kang ◽  
Wanhyung Lee
Keyword(s):  
Regression Analysis ◽  
Negative Binomial ◽  
Metabolic Diseases ◽  
Young Male ◽  
Negative Binomial Regression ◽  
Final Analysis ◽  
Work Status ◽  
Breakfast Skipping ◽  
Metabolic Outcomes ◽  
Binomial Regression

Abstract Background The association between breakfast skipping and abnormal metabolic outcomes remains controversial. A comprehensive study with various stratified data is required. Objective The aim of this study was to investigate the relationship between abnormal metabolic outcomes and breakfast skipping by sex, age, and work status stratification. Methods We used data from the Korea National Health and Nutrition Examination Surveys from 2013 to 2018. A total of 21,193 (9022 men and 12,171 women) participants were included in the final analysis. The risk of metabolic outcomes linked to breakfast skipping was estimated using the negative binomial regression analysis by sex, work status, and age stratification. Results A total of 11,952 (56.4%) participants consumed breakfast regularly. The prevalence of abnormal metabolic outcomes was higher among those with irregular breakfast consumption habits. Among young male workers, negative binomial regression analysis showed that irregular breakfast eaters had a higher risk of abnormal metabolic outcomes, after adjusting for covariates (odds ratio, 1.15; 95% confidence interval, 1.03–1.27). Conclusions The risk of abnormal metabolic outcomes was significant in young men in the working population. Further studies are required to understand the association of specific working conditions (working hours or shift work) with breakfast intake status and the risk of metabolic diseases.

scholarly journals Time-restricted feeding regulates circadian rhythm of murine uterine clock

2021 ◽  
Author(s):  
Takashi Hosono ◽  
Masanori Ono ◽  
Takiko Daikoku ◽  
Michihiro Mieda ◽  
Satoshi Nomura ◽  
...  
Keyword(s):  
Circadian Rhythm ◽  
Circadian Rhythms ◽  
Protein Expression ◽  
Western Blot ◽  
Active Phase ◽  
Active Period ◽  
Restricted Feeding ◽  
Group Iii ◽  
Breakfast Skipping ◽  
Group I

Abstract Background Skipping breakfast is associated with dysmenorrhea in young women. This suggests that the delay of food intake in the active phase impairs uterine functions by interfering with circadian rhythms. Objective To examine the relationship between the delay of feeding and uterine circadian rhythms, we investigated the effects of the first meal occasion in the active phase on the uterine clock. Methods Zeitgeber time (ZT) was defined as ZT 0 (8:45) with lights on and ZT 12 (20:45) with lights off. Young female mice (8 weeks of age) were divided into 3 groups: group I (ad-libitum feeding), group II (time-restricted feeding during ZT12–16, initial 4 hours of the active period), and group III (time-restricted feeding during ZT20–24, last 4 hours of the active period, a breakfast-skipping model). After two weeks of dietary restriction, mice in each group were sacrificed at 4-hour intervals and the expression profiles of uterine clock genes, Bmal1, Per1, Per2, and Cry1, were examined. Results qPCR and Western blot analyses demonstrated synchronized circadian clock gene expression within the uterus. Immunohistochemical analysis confirmed that Bmal1 protein expression was synchronized among the endometrium and myometrium. In groups I and II, mRNA expression of Bmal1 was elevated after ZT12 at the start of the active phase. In contrast, Bmal1 expression was elevated just after ZT20 in group III, showing that the uterine clock rhythm had shifted 8 hours backward. The changes in Bmal1 protein expression were confirmed by Western blot analysis. Conclusion This study is the first to indicate that time-restricted feeding regulates a circadian rhythm of the uterine clock that is synchronized throughout the uterine body. These findings suggest that the uterine clock system is a new candidate to explain the etiology of breakfast skipping-induced uterine dysfunction.

The anorectic effect of fenfluramine is influenced by sex and stage of the estrous cycle in rats

2005 ◽  
Vol 288 (6) ◽  
pp. R1486-R1491 ◽  
Author(s):  
Lisa A. Eckel ◽  
Heidi M. Rivera ◽  
Deann P. D. Atchley
Keyword(s):  
Food Intake ◽  
Estrous Cycle ◽  
Female Rats ◽  
Male Rats ◽  
Gonadal Hormone ◽  
Estrous Female ◽  
Male And Female Rats ◽  
Daily Food ◽  
Hormone Status ◽  
Anorectic Effect

The controls of food intake differ in male and female rats. Daily food intake is typically greater in male rats, relative to female rats, and a decrease in food intake, coincident with the estrous stage of the ovarian reproductive cycle, is well documented in female rats. This estrous-related decrease in food intake has been attributed to a transient increase in the female rat's sensitivity to satiety signals generated during feeding bouts. Here, we investigated whether sex or stage of the estrous cycle modulate the satiety signal generated by fenfluramine, a potent serotonin (5-HT) releasing agent. To examine this hypothesis, food intake was monitored in male, diestrous female, and estrous female rats after intraperitoneal injections of 0, 0.25, and 1.0 mg/kg d-fenfluramine. The lower dose of fenfluramine decreased food intake only in diestrous and estrous females, suggesting that the minimally effective anorectic dose of fenfluramine is lower in female rats, relative to male rats. Although the larger dose of fenfluramine decreased food intake in both sexes, the duration of anorexia was greater in diestrous and estrous female rats, relative to male rats. Moreover, the magnitude of the anorectic effect of the larger dose of fenfluramine was greatest in estrous rats, intermediate in diestrous rats, and least in male rats. Thus our findings indicate that the anorectic effect of fenfluramine is modulated by gonadal hormone status.

scholarly journals Food intake in Slovenian adolescents and adherence to the Optimized Mixed Diet: a nationally representative study

2011 ◽  
Vol 15 (4) ◽  
pp. 600-608 ◽  
Author(s):  
Helena Kobe ◽  
Matevž Štimec ◽  
Cirila Hlastan Ribič ◽  
Nataša Fidler Mis
Keyword(s):  
Food Intake ◽  
Nutrition Education ◽  
Dietary Habits ◽  
Health Centre ◽  
Dietary Guidelines ◽  
Mixed Diet ◽  
Food Groups ◽  
Eating Pattern ◽  
Representative Study ◽  
Geographical Regions

AbstractObjectivesTo investigate the food intake of Slovenian adolescents and to compare it with food-based dietary guidelines developed for children and adolescents, named the Optimized Mixed Diet (OMD). The OMD is a useful tool for the evaluation of food intake of adolescents.DesignAll adolescents completed an FFQ at a regional health centre; a subgroup also completed a 3 d weighed dietary protocol at home.SettingThis study is a part of the first national representative study on the dietary habits of Slovenian adolescents.SubjectsThis cross-sectional study included a representative sample of 2813 Slovenian adolescents entering high school, aged 14–17 years, from all ten geographical regions of Slovenia.ResultsThe greatest deviations from the recommended intakes of the main food groups in the OMD were significantly lower intakes of (P < 0·001, mean): vegetables (179 and 163 g/d in boys and girls, respectively), bread/cereals (271 and 226 g/d), potatoes/rice/pasta (212 and 163 g/d); in boys also a significantly lower intake of fruits (mean: 321 g/d, P < 0·001) and a significantly higher intake of meat/meat products (mean: 126 g/d, P < 0·001). Additionally, the results show too high intake of sugar-sweetened beverages and too low intakes of fish and plant oils in both genders.ConclusionsThe food intake pattern of Slovenian adolescents deviates markedly from a healthy eating pattern. Nutrition education and interventions are needed for Slovenian adolescents.

Regulation of food intake by neuropeptide Y in goldfish

2000 ◽  
Vol 279 (3) ◽  
pp. R1025-R1034 ◽  
Author(s):  
Yuwaraj K. Narnaware ◽  
Pierre P. Peyon ◽  
Xinwei Lin ◽  
Richard E. Peter
Keyword(s):  
Food Intake ◽  
Neuropeptide Y ◽  
Mrna Levels ◽  
Food Ration ◽  
Y1 Receptor ◽  
Daily Food ◽  
Daily Food Ration ◽  
Brain Ventricle ◽  
Dose Dependent Increase ◽  
Dose Dependent

In mammals, neuropeptide Y (NPY) is a potent orexigenic factor. In the present study, third brain ventricle (intracerebroventricular) injection of goldfish NPY (gNPY) caused a dose-dependent increase in food intake in goldfish, and intracerebroventricular administration of NPY Y1-receptor antagonist BIBP-3226 decreased food intake; the actions of gNPY were blocked by simultaneous injection of BIBP-3226. Goldfish maintained on a daily scheduled feeding regimen display an increase in NPY mRNA levels in the telencephalon-preoptic area and hypothalamus shortly before feeding; however, a decrease occured in optic tectum-thalamus. In both fed and unfed fish, brain NPY mRNA levels decreased after scheduled feeding. Restriction in daily food ration intake for 1 wk or food deprivation for 72 h resulted in increased brain NPY mRNA levels. Results from these studies demonstrate that NPY is a physiological brain signal involved in feeding behavior in goldfish, mediating its effects, at least in part, through Y1-like receptors in the brain.

Limits to sustained energy intake

2001 ◽  
Vol 204 (11) ◽  
pp. 1947-1956 ◽  
Author(s):  
M. S. Johnson ◽  
S. C. Thomson ◽  
J. R. Speakman
Keyword(s):  
Food Intake ◽  
Energy Intake ◽  
Litter Size ◽  
Resting Metabolic Rate ◽  
Control Group ◽  
Lower Mass ◽  
Daily Food Intake ◽  
Energy Demands ◽  
Daily Food ◽  
Pregnancy And Lactation

SUMMARYTo determine whether mice were limited in their capacity to absorb energy during late lactation, we attempted to increase the energy burden experienced by a group of female mice during late lactation by mating them at the postpartum oestrus, hence combining the energy demands of pregnancy and lactation. These experimental mice were therefore concurrently pregnant and lactating in their first lactation, and were followed through a normal second lactation. In a control group, females also underwent two lactations but sequentially, with the second mating after the first litter had been weaned. Maternal mass and food intake were measured throughout the first lactation, second pregnancy and second lactation. Maternal resting metabolic rate (RMR) was measured prior to the first mating and then at the peak of both the first and second lactations. Litter size and litter mass were also measured throughout both lactations. In the first lactation, experimental mice had a lower mass-independent RMR (F1,88=5.15, P=0.026) and raised significantly heavier pups (t=2.77, d.f.=32, P=0.0093) than the control mice. Experimental mice delayed implantation at the start of the second pregnancy. The extent of the delay was positively related to litter size during the first lactation (F1,19=4.58, P=0.046) and negatively related to mean pup mass (F1,19=5.78, P=0.027) in the first lactation. In the second lactation, the experimental mice gave birth to more (t=2.75, d.f.=38, P=0.0092) and lighter (t=−5.01, d.f.=38, P&lt;0.0001) pups than did the controls in their second lactation. Maternal asymptotic daily food intake of control mice in the second lactation was significantly higher (t=−4.39, d.f.=37, P=0.0001) than that of the experimental mice and higher than that of controls during their first lactation. Despite the added burden on the experimental females during their first lactation, there was no increase in their food intake, which suggested that they might be limited by their capacity to absorb energy. However, control females appeared to be capable of increasing their asymptotic food intake beyond the supposed limits estimated previously, suggesting that the previously established limit was not a fixed central limitation on food intake. As RMR increased in parallel with the increase in food intake during the second lactation of control mice, the sustained energy intake remained at around 7.0×RMR.

Energy intake and fur in summer- and winter-acclimated Siberian hamsters (Phodopus sungorus)

2001 ◽  
Vol 281 (2) ◽  
pp. R519-R527 ◽  
Author(s):  
Alexander S. Kauffman ◽  
Alessandra Cabrera ◽  
Irving Zucker
Keyword(s):  
Food Intake ◽  
Energy Intake ◽  
Ventral Surface ◽  
Phodopus Sungorus ◽  
Ambient Temperatures ◽  
Siberian Hamsters ◽  
Daily Food ◽  
Brown Adipose ◽  
Wide Range ◽  
The Impact

Few studies have directly addressed the impact of fur on seasonal changes in energy intake. The daily food intake of Siberian hamsters ( Phodopus sungorus) was measured under simulated summer and winter conditions in intact animals and those with varying amounts of pelage removed. Energy intake increased up to 44% above baseline control values for approximately 2–3 wk after complete shaving. Increases in food intake varied with condition and were greater in hamsters housed in short than long day lengths and at low (5°C) than moderate (23°C) ambient temperatures. Removal of 8 cm2 of dorsal fur, equivalent to 30% of the total dorsal fur surface, increased food intake, but removal of 4 cm2 had no effect. An 8-cm2 fur extirpation from the ventral surface did not increase food consumption. Food intake was not influenced differentially by fur removal from above brown adipose tissue hot spots. Fur plays a greater role in energy balance in winter- than summer-acclimated hamsters and conserves energy under a wide range of environmental conditions.

Breed and sex differences in equally mature sheep and goats 1. Growth and food intake

1987 ◽  
Vol 45 (2) ◽  
pp. 239-260 ◽  
Author(s):  
M. L. Thonney ◽  
St C. S. Taylor ◽  
T. H. McClelland
Keyword(s):  
Food Intake ◽  
Conversion Efficiency ◽  
Mammalian Species ◽  
The Body ◽  
Food Conversion ◽  
Size Scaling ◽  
Daily Food ◽  
Fleece Weight ◽  
Mature Size ◽  
Food Conversion Efficiency

ABSTRACTGenetic size-scaling accounts for most of the variation found among mammalian species in food intake and growth rate, with food conversion efficiency independent of the body size of the species. Is the same true of breeds and strains within species?Animals from Soay, Welsh Mountain, Southdown, Finish Landrace, Jacob, Wiltshire Horn and Oxford Down sheep breeds and from a breed of feral goats were grown to 0·40, 0·52, 0·64 or 0·76 of the mean mature weight of their breed and sex. Food was offered ad libitum and individually recorded.Allometric growth coefficients were obtained for fleece weight, femur weight and femur length. Fleece was late maturing and femur early.Breed and sex size-scaling coefficients, obtained by regression of breed and sex means on mature size, were similar to those found at the species level for age from conception to slaughter, time taken to mature and food conversion efficiency. Coefficients were higher than expected for total and daily food consumption, especially at early stages of maturity. Most breed coefficients were close to expectation while sex coefficients were somewhat higher than expected.There were significant breed deviations: Welsh Mountain, Oxford Down and probably Soay sheep required less time and Jacob sheep and feral goats required more time to mature than expected from differences in mature size. Soay and Welsh Mountain sheep appeared to be more efficient and feral goats and Jacob sheep less efficient food converters over the same maturity interval.

Sign in / Sign up

Export Citation Format

Share Document