scholarly journals Nutraceuticals and Cancer: Potential for Natural Polyphenols

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3834
Author(s):  
Jessica Maiuolo ◽  
Micaela Gliozzi ◽  
Cristina Carresi ◽  
Vincenzo Musolino ◽  
Francesca Oppedisano ◽  
...  
Keyword(s):  
Eating Habits ◽  
Natural Antioxidants ◽  
Cancer Disease ◽  
Anticancer Properties ◽  
Patients With Cancer ◽  
Disease States ◽  
Unhealthy Eating ◽  
Anticancer Treatment ◽  
Polyphenolic Profile ◽  
Cancerous Cells

Cancer is one of the leading causes of death globally, associated with multifactorial pathophysiological components. In particular, genetic mutations, infection or inflammation, unhealthy eating habits, exposition to radiation, work stress, and/or intake of toxins have been found to contribute to the development and progression of cancer disease states. Early detection of cancer and proper treatment have been found to enhance the chances of survival and healing, but the side effects of anticancer drugs still produce detrimental responses that counteract the benefits of treatment in terms of hospitalization and survival. Recently, several natural bioactive compounds were found to possess anticancer properties, capable of killing transformed or cancerous cells without being toxic to their normal counterparts. This effect occurs when natural products are associated with conventional treatments, thereby suggesting that nutraceutical supplementation may contribute to successful anticancer therapy. This review aims to discuss the current literature on four natural bioactive extracts mostly characterized by a specific polyphenolic profile. In particular, several activities have been reported to contribute to nutraceutical support in anticancer treatment: (1) inhibition of cell proliferation, (2) antioxidant activity, and (3) anti-inflammatory activity. On the other hand, owing to their attenuation of the toxic effect of current anticancer therapies, natural antioxidants may contribute to improving the compliance of patients undergoing anticancer treatment. Thus, nutraceutical supplementation, along with current anticancer drug treatment, may be considered for better responses and compliance in patients with cancer. It should be noted, however, that when data from studies with bioactive plant preparations are discussed, it is appropriate to ensure that experiments have been conducted in accordance with accepted pharmacological research practices so as not to disclose information that is only partially correct.

scholarly journals The intersection of COVID-19 and cancer: signaling pathways and treatment implications

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhi Zong ◽  
Yujun Wei ◽  
Jiang Ren ◽  
Long Zhang ◽  
Fangfang Zhou
Keyword(s):  
Signaling Pathways ◽  
Health Concern ◽  
Type I ◽  
The Novel ◽  
Checkpoint Signaling ◽  
Patients With Cancer ◽  
Advantages And Disadvantages ◽  
Anticancer Treatment ◽  
Severe Infections ◽  
Novel Coronavirus

AbstractThe outbreak of the novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a serious public health concern. Patients with cancer have been disproportionately affected by this pandemic. Increasing evidence has documented that patients with malignancies are highly susceptible to severe infections and mortality from COVID-19. Recent studies have also elucidated the molecular relationship between the two diseases, which may not only help optimize cancer care during the pandemic but also expand the treatment for COVID-19. In this review, we highlight the clinical and molecular similarities between cancer and COVID-19 and summarize the four major signaling pathways at the intersection of COVID-19 and cancer, namely, cytokine, type I interferon (IFN-I), androgen receptor (AR), and immune checkpoint signaling. In addition, we discuss the advantages and disadvantages of repurposing anticancer treatment for the treatment of COVID-19.

scholarly journals Nutritional Status Disorders in Student Population

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Djordje Stevanovic ◽  
Mina Poskurica ◽  
Jovan Jovanovic ◽  
Miodrag Sreckovic ◽  
Vladimir Zdravkovic ◽  
...  
Keyword(s):  
Physical Activity ◽  
Nutritional Status ◽  
Health Problem ◽  
Eating Habits ◽  
Student Population ◽  
Regular Physical Activity ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Unhealthy Eating ◽  
Significant Difference

Abstract Obesity is a global health problem associated with numerous pathological conditions. Unhealthy eating habits and the lack of regular physical activity are considered the most common cause of disordered nutritional status. The aim of the research was to determine the nutritional status in student population and the predictors which determine this condition. The cross-sectional study was conducted on 262 students of the Faculty of Medical Sciences in Kragujevac (130 males and 132 females). Body weight and height, body mass index (BMI) and visceral fat (VF) were measured. Each respondent completed a specially designed questionnaire considering sociodemographic data, eating habits and physical activity. The majority of students have normal BMI values (75.6%), 5.3% were classified as underweight, 14.9% as over-weight and 4.3% as obese. Normal VF values were found in 93.1% of subjects, while high in 5.7% and very high in 1.1%. A statistically significant difference in BMI and VF values was found between male and female gender (24.41 vs. 21.05, Sig = 0.000 and 5.47 vs. 3.07, Sig = 0.000, respectively), as well as between students of the first 4 and the last 2 years of study (Sig = 0.019 and 0.000 respectively). Unhealthy eating habits, such as the consumption of sweets, snacks, fast foods and white bread, and the absence of regular physical activity were statistically more present in overweight/obese respondents. Given the significant presence of pre-obesity/obesity in the examined population, corrective measures should be taken in this population in order to avoid a major health problem in the future.

Zinc-specific Food Frequency Questionnaire To Assess College Women’s Eating Habits

2009 ◽  
Vol 70 (4) ◽  
pp. 204-208 ◽  
Author(s):  
Janet M. Lacey ◽  
Deanne U. Zotter
Keyword(s):  
Food Frequency Questionnaire ◽  
Assessment Tool ◽  
Eating Habits ◽  
Eating Behaviour ◽  
Eating Attitudes ◽  
Eating Attitude ◽  
Food Frequency ◽  
Unhealthy Eating ◽  
Starting Point ◽  
Eat 26

Zinc deficiency has been reported in individuals with eating disorders, the risks of which increase during the adolescent and early adult years. A food frequency questionnaire (FFQ) specific for zinc-rich foods was tested for its usefulness in identifying problematic eating behaviour tendencies in college-age women. Ninety-two female students enrolled in a university introductory psychology course volunteered to complete demographic information, the Eating Attitudes Test (EAT-26), and a zinc-specific FFQ (ZnFFQ). Relationships among estimated zinc intakes, food/lifestyle habits, and eating attitude variables were examined. Twenty-five women had estimated intakes below the Recommended Dietary Allowance (RDA) for zinc. Individuals in the highest zinc intake group (over twice the RDA) had a tendency to score higher on the EAT-26 and the bulimia subscale. Vegetarians also scored high on the EAT-26. Although our data are limited, the ZnFFQ should be studied further to determine whether it could play a useful role in identifying individuals at risk for bulimia. The ZnFFQ is a simple, non-confrontational assessment tool and may be a helpful starting point for identifying women with unhealthy eating habits.

scholarly journals The Role of the Passive Voice Mindset in Regulating Healthy Eating

2017 ◽  
Vol 9 (2) ◽  
pp. 37
Author(s):  
Ibrahim Senay ◽  
Muhammet Usak ◽  
Zeynep Ceren Acarturk
Keyword(s):  
Healthy Eating ◽  
Eating Habits ◽  
Passive Voice ◽  
Active Voice ◽  
The Past ◽  
It Impacts ◽  
Unhealthy Eating

Talking about eating in the passive, as opposed to the active voice, (e.g., The cake will be eaten vs. I will eat the cake) can lead people to see the act of eating to be triggered by the food to a greater extent, leading to the continuation of past eating habits. Depending on whether or not the past habits are healthy, the motivation for healthy eating may change as a result. In study 1, writing passive sentences increased the motivation for healthy eating to the extent that people reported eating healthy in the past. Moreover, in study 2 across 127 languages spoken in 94 countries, when the acted-upons of actions (e.g., the food in the act of eating) became relatively more salient in a language, people became more likely to act on cultural habits that may be relatively healthier, decreasing unhealthy eating. The results are important for understanding the perceived role of food in starting eating as it impacts healthy eating across cultures.

scholarly journals Association between area-level education and the co-occurrence of behavior-related risk factors: a multilevel analysis

2019 ◽  
Vol 22 ◽  
Author(s):  
Antonio Fernando Boing ◽  
SV Subramanian ◽  
Alexandra Crispim Boing
Keyword(s):  
Risk Factors ◽  
Chronic Diseases ◽  
Educational Level ◽  
Physical Inactivity ◽  
Eating Habits ◽  
Significant Proportion ◽  
Simultaneous Occurrence ◽  
Cross Sectional ◽  
Individual Level ◽  
Unhealthy Eating

ABSTRACT: Introduction: This study aimed to investigate the association of four different risk factors for chronic diseases and accumulation of these health behaviors with area-level education, regardless of individual-level characteristics in Brazil. Methods: A population-based cross-sectional study was carried out in Southern Brazil including 1,720 adults in 2009/2010. The simultaneous occurrence of tobacco smoking, abusive drinking, unhealthy eating habits, and physical inactivity was investigated. Using multilevel models, we tested whether area-level education was associated with each risk factor and with the co-occurrence of them after controlling sociodemographic individual-level variables. Results: We observed a between-group variance of 7.79, 7.11, 6.84 and 1.08% for physical inactivity, problematic use of alcohol, unhealthy eating habits, and smoking, respectively. The between-group variance for the combination of four behaviors was 14.2%. Area-level education explained a significant proportion of the variance observed in physical inactivity and unhealthy eating habits. Residents of low educational level neighborhoods showed a 2.40 (95%CI 1.58 - 3.66) times higher chance of unhealthy eating and 1.78 (95%CI 1.19 - 2.67) times higher chance of physical inactivity. The likelihood of individuals with two or three/four risk factors was simultaneously higher among residents of low educational level neighborhoods. Conclusion: Public policies should consider the area-level characteristics, including education to control risk factors for chronic diseases.

scholarly journals Synthesis of Al-Based Metal-Organic Framework in Water With Caffeic Acid Ligand and NaOH as Linker Sources With Highly Efficient Anticancer Treatment

2021 ◽  
Vol 9 ◽  
Author(s):  
Malihe Zeraati ◽  
Abbas Rahdar ◽  
Dora I. Medina ◽  
Ghasem Sargazi
Keyword(s):  
Electron Microscopy ◽  
Green Synthesis ◽  
Metal Organic Framework ◽  
Cost Effective ◽  
Spherical Particles ◽  
Anticancer Properties ◽  
Synthesis Route ◽  
Anticancer Treatment ◽  
Metal Organic ◽  
Organic Framework

In this study, novel nanostructures of aluminum base metal-organic framework (Al-MOF) samples were synthesized using a sustainable, non-toxic, and cost-effective green synthesis route. Satureja hortensis extract was used as an effective source of linker for the development of the Al-MOF structures. The Fourier-transformed infrared (FTIR) spectrum confirmed the presence of characterization bonds related to the Al-MOF nanostructures synthesized by the green synthesis route. The scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analyses revealed that the sample synthesized by Na2-CA was composed of multilayers, although it was agglomerated, but it had dispersed and occurred in spherical particles, indicating active organic matter. N2 adsorption/desorption isotherms demonstrated the significant porosity of the Al-MOF samples that facilitate the high potential of these nanostructures in medical applications. The anticancer treatment of Al-MOF samples was performed with different concentrations using the MTT standard method with untreated cancer cells for 24 and 48 h periods. The results exhibited the significant anticancer properties of Al-MOF samples developed in this study when compared with other MOF samples. Thus, the development of a novel Al-MOF and its application as a natural linker can influence the anticancer treatment of the samples. According to the results, the products developed in this study can be used in more applications such as biosensors, catalysts, and novel adsorbents.

Glycans in Immunologic Health and Disease

2021 ◽  
Vol 39 (1) ◽  
Author(s):  
Julie Y. Zhou ◽  
Brian A. Cobb
Keyword(s):  
Immune Regulation ◽  
Secreted Proteins ◽  
Annual Review ◽  
Publication Date ◽  
Cancer Disease ◽  
Disease States ◽  
Immunological Recognition ◽  
Immunologic Disease ◽  
Health And Disease ◽  
Living Organisms

The surfaces of all living organisms and most secreted proteins share a common feature: They are glycosylated. As the outermost-facing molecules, glycans participate in nearly all immunological processes, including driving host-pathogen interactions, immunological recognition and activation, and differentiation between self and nonself through a complex array of pathways and mechanisms. These fundamental immunologic roles are further cast into sharp relief in inflammatory, autoimmune, and cancer disease states in which immune regulation goes awry. Here, we review the broad impact of glycans on the immune system and discuss the changes and clinical opportunities associated with the onset of immunologic disease. Expected final online publication date for the Annual Review of Immunology, Volume 39 is April 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Innovative Aspects of Virtual Reality and Kinetic Sensors for Significant Improvement Using Fireworks Algorithm in a Wii Game of a Collaborative Sport

2021 ◽  
pp. 991-1008
Author(s):  
Alberto Ochoa-Zezzatti ◽  
José Mejia ◽  
Saúl González ◽  
Ismael Rodríguez ◽  
Jose Peinado ◽  
...  
Keyword(s):  
Eating Habits ◽  
Weather Conditions ◽  
The United States ◽  
Junk Food ◽  
Fireworks Algorithm ◽  
Adverse Weather Conditions ◽  
Unhealthy Eating ◽  
Adverse Weather ◽  
Sedentary Life ◽  
Olympic Sport

A new report on childhood obesity is published every so often. The bad habits of food and the increasingly sedentary life of children in a border society has caused an alarming increase in the cases of children who are overweight or obese. Formerly, it seemed to be a problem of countries with unhealthy eating habits, such as the United States or Mexico in Latin America, where junk food is part of the diet in childhood. However, obesity is a problem that we already have around the corner and that is not so difficult to fight in children. In the present research the development of an application that reduces the problem of the lack of movement in the childhood of a smart city is considered a future problem which it is the main contribution, coupled with achieving an innovative way of looking for an Olympic sport without the complexity of physically moving to a space with high maintenance costs and considering the adverse weather conditions.

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