scholarly journals Antiviral Activities of Eucalyptus Essential Oils: Their Effectiveness as Therapeutic Targets against Human Viruses

2021 ◽  
Vol 14 (12) ◽  
pp. 1210
Author(s):  
Daniel Mieres-Castro ◽  
Sunny Ahmar ◽  
Rubab Shabbir ◽  
Freddy Mora-Poblete
Keyword(s):  
Essential Oil ◽  
Infectious Diseases ◽  
Essential Oils ◽  
Molecular Mechanisms ◽  
Inflammatory Responses ◽  
Antiviral Agent ◽  
Antiviral Activities ◽  
Direct Binding ◽  
Human Viruses ◽  
Eucalyptus Essential Oil

Given the limited therapeutic management of infectious diseases caused by viruses, such as influenza and SARS-CoV-2, the medicinal use of essential oils obtained from Eucalyptus trees has emerged as an antiviral alternative, either as a complement to the treatment of symptoms caused by infection or to exert effects on possible pharmacological targets of viruses. This review gathers and discusses the main findings on the emerging role and effectiveness of Eucalyptus essential oil as an antiviral agent. Studies have shown that Eucalyptus essential oil and its major monoterpenes have enormous potential for preventing and treating infectious diseases caused by viruses. The main molecular mechanisms involved in the antiviral activity are direct inactivation, that is, by the direct binding of monoterpenes with free viruses, particularly with viral proteins involved in the entry and penetration of the host cell, thus avoiding viral infection. Furthermore, this review addresses the coadministration of essential oil and available vaccines to increase protection against different viruses, in addition to the use of essential oil as a complementary treatment of symptoms caused by viruses, where Eucalyptus essential oil exerts anti-inflammatory, mucolytic, and spasmolytic effects in the attenuation of inflammatory responses caused by viruses, in particular respiratory diseases.

scholarly journals New Products Based on Essential Oils for the Treatment of Medical Furs

2019 ◽  
Vol 70 (3) ◽  
pp. 765-768
Author(s):  
Olga Niculescu ◽  
Luminita Albu ◽  
Maria Carmen Loghin ◽  
Carmen Gaidau ◽  
Lucretia Miu ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
New Products ◽  
Chemical Characterization ◽  
Muscular Pain ◽  
Natural Oils ◽  
Physical Chemical ◽  
Final Treatment ◽  
Eucalyptus Essential Oil

Sheep furskins for medical use were tanned with non-metallic tanning materials (syntans based on phenolsulphonic acids and aromatic oxysulfones). Sanitation of medical furs was made using essential oils, with therapeutic effect, in the final treatment of tanned furs. The paper refers to obtaining and physical-chemical characterization of new products based on natural oils (eucalyptus essential oil), ethyl alcohol, non-ionogenic surfactants from the category of polyethoxylated fatty alcohols and polyethylene glycols and water, for the treatment of medical furs. Eucalyptus essential oil used to obtain new products was analysed using GC-MS and spectral analyses. The furs will be used to make natural fur articles for medical purposes (lumbar belts, knee pads, elbow pads etc.) to relieve rheumatic and muscular pain of the affected target areas, keeping the area warm and potentiating the medical treatment of the patients who suffer from these conditions.

scholarly journals ESSENTIAL OILS OBTAINED FROM EUCALYPTUS AND CYMBOPOGON LEAVES BY STEAM DISTILLATION FOR MAKING NATURAL MIXTURE HAVING EFFECT AS A MOSQUITO REPELLENT

2021 ◽  
Vol 58 (6A) ◽  
pp. 236
Author(s):  
Ba Van Nguyen ◽  
Tran Thi Kieu Ngân ◽  
Nguyen Thi My Ngoc ◽  
Ngo Nguyen Thuy Hang ◽  
Nguyen Thi Ngoc Chau ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Coconut Oil ◽  
Preliminary Treatment ◽  
Distilled Water ◽  
Mosquito Repellent ◽  
Eucalyptus Oil ◽  
Eucalyptus Leaves ◽  
Natural Mixture ◽  
Eucalyptus Essential Oil

Abstract-HCTN7. Natural essential oils of plant have been applied over the world becausef these biosafety natural compounds. Applicant levels from the steaming pot among the common people to the raw essential oils or pure extract essence from original natural sources for making special products. Eucalyptus essential oil obtains from Eucalyptus leaves contain 998 mg/L α-eucalyptol, Cymbopogon essential oil obtains from lemon grasses contain 64,8% citral. These essential oils have been paid attention because of there were abundant raw materials in the Mekong Delta area. Therefore, the study was conducted to aim of extracting essential oils from Eucalyptus and Cymbopogon leaves as well as examminate their effect on mosquito repellent. The factors affecting the amount of extracted oils are the time to withered materials (0 h; 2.5 h; 5 h), how the way to preliminary treatment of the materials (crushing or without crushing), the distilled water aidding (400 mL, 500 mL, 600 mL)/300g materials, the distillation time (2 h; 2.5 h; 3 h). The data was evaluated by statistical program. Mixing ratio of Cymbopogon oil: Eucalyptus oil: coconut oil, one of the important criteria to be investigated for evaluating the ability to repel mosquitoes is in turn (40:10:50), (35:15:50), (30:20:50). Experimental results reveal that crushing (Cymbopogon), without crushing (Eucalyptus) of fresh materials, 500 mL of distilled water aidding, 3 h of distillation time were the best during the oil extraction process. The contents of mixing formula of the Cymbopogon essiential oil: Eucalyptus essiential oil: coconut oil (40: 10: 50) is the most effective with the ability to falling mosquitoes only after 5 minutes and killing 84.67% mosquitoes after 24 hours. The natural mixture of Cymbopogon oil, Eucalyptus oil, and coconut oil, safety for human health and more friendly to the environment.Keywords: Coconut oil, Eucalyptus essential oil, Eucalyptus leaves, Cymbopogon essential oil, Cymbopogon leaves, mosquito repellent, steam distillation.Classification numbers:1.4.6.

scholarly journals BIOACTIVITY OF EUCALYPTUS ESSENTIAL OIL

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Deep R Darji ◽  
Palak Sapra ◽  
Dr. Archana U. Mankad
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Current Literature ◽  
Chemical Components ◽  
Plant Parts ◽  
Cultivated Plant ◽  
Medicinal Properties ◽  
Major Chemical ◽  
Eucalyptus Plant ◽  
Eucalyptus Essential Oil

Eucalyptus plant belongs to myrtaceae family, it commonly known as eucalyptus. In line with worldwide, it’s worldwide cultivated plant. Eucalyptus plant parts has various and different bioactivities. The main chemical components of eucalyptus plant is 1, 8 cineole. It has very strong medicinal properties. And other major chemical components are limonene, ?pinene, P-Cymene, Terpine-1-ol, Globulol. Eucalyptus essential oil has strong bioactivities like antifungal, antibacterial, antioxidant, and antimycotoxigenic activities. Eucalyptus essential oil also has preservative properties. A review provides an overview of the current literature on eucalyptus essential oils mainly antifungal, antimycotoxigenic activity and their uses.

Chemical Composition and Antibacterial Activity of Essential Oils of Three Medicinal Plants from Algerian Semi-Arid Climatic Zone

2018 ◽  
Vol 16 (S1) ◽  
pp. S155-S163 ◽  
Author(s):  
S. Mehalaine ◽  
O. Belfadel ◽  
T. Menasria ◽  
A. Messaili
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Rosmarinus Officinalis ◽  
Salvia Officinalis ◽  
Thymus Algeriensis

The present study was carried out to determine, for the first time, the chemical composition and antibacterial activity of essential oils derived from the aerial parts of three aromatic plants Thymus algeriensis Boiss & Reut, Rosmarinus officinalis L., and Salvia officinalis L. growing under semiarid conditions. The essential oils were chemically analyzed and identified by gas chromatography (GC) and GC/ mass spectrometry (GC/MS) and their antimicrobial activity was individually evaluated against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa using both agar disk diffusion and agar dilution methods. The major constituents of Thymus algeriensis essential oil were identified as camphor (13.62%), 1,8-cineol (6.00%), borneol (5.74%), viridiflorol (4.00%), and linalool (3.93%). For Rosmarinus officinalis essential oil, 48 compounds were characterized, of which the main constituents were camphor (17.09%), Z-β-ocimene (10.88%), isoborneol (9.68%), α-bisabolol (7.89%), and borneol (5.11%). While, Salvia officinalis essential oil was characterized by β-thujone (16.44%), followed by viridiflorol (10.93%), camphor (8.99%), 1,8-cineol (8.11%), trans-caryophyllene (5.85%), and α-humulene (4.69%) as the major components. Notably, results from antibacterial screening indicated that Thymus algeriensis and Salvia officinalis essential oils exhibited a strong inhibitory effect against both Escherichia coli and Staphylococcus aureus compared to Rosmarinus officinalis essential oil. Further, less activity was recorded against Pseudomonas aeruginosa for the three tested essential oils.

Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis

2019 ◽  
Vol 70 (6) ◽  
pp. 2015-2020
Author(s):  
Silvia Robu ◽  
Aurelia Romila ◽  
Olimpia Dumitriu Buzia ◽  
Adrian Florin Spac ◽  
Camelia Diaconu ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Plant Material ◽  
Mobile Phase ◽  
Chromatographic Method ◽  
Salvia Officinalis ◽  
Salvia Officinalis L ◽  
Gas Chromatographic Method

Numerous articles on Salvia officinalis L. have been published regarding the composition of their essential oil. The considerable variation found may be due to the quality of the plant material as well as to the methods used for analysis. A simple GC-MS method was developed and optimized in the QbD approach, for the determination of sage essential oils. The optimization of GC-MS analysis was performed using different mobile phase flows, injection volumes, split ratios and temperature programs. The optimized method proved to be simple and can be successfully applied for the determination of sage essential oils.

Review of the Essential Oil Composition of Iranian Endemic and Native Taxa of Apiaceae (Umbelliferae)

2020 ◽  
Vol 24 (9) ◽  
pp. 909-1009
Author(s):  
Maryam Akaberi ◽  
Zahra Tayarani-Najaran ◽  
Iraj Mehregan ◽  
Javad Asili ◽  
Amirhossein Sahebkar ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Essential Oil Composition ◽  
Present Review ◽  
Aromatic Plants ◽  
Oil Composition

One of the most important families of Iranian flora is Apiaceae (Umbelliferae). Most of the species of this family are aromatic plants and rich in essential oils with diverse structures. In the present review, the essential oil composition of 63 genera comprising 141 Apiaceae (66.4% native 33.6% endemic) is summarized.

Chemical variability and antioxidant activities of the essential oils of the aerial parts of Ammoides verticillata and the roots of Carthamus caeruleus and their synergistic effect in combination

2020 ◽  
Vol 23 ◽  
Author(s):  
Imane Rihab Mami ◽  
Noria Merad-Boussalah ◽  
Mohammed El Amine Dib ◽  
Boufeldja Tabti ◽  
Jean Costa ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Natural Food ◽  
Chemical Compositions ◽  
Chemical Variability ◽  
Ammoides Verticillata

Aim and Objective: Oxidative stress is implicated in the development and progression of many disease. Some of appropriate actions that could be initiated to taken to resolve the problem of these diseases are search for new antioxidant substances isolated from plants. The aims of this study were to study the intraspecies variations of A. verticillata and C. caeruleus essential oils from 8 locations using statistical analysis, the in vitro antioxidant properties of collective essential oils and in combinations. Materials and Methods: The essential oils were analyzed by GC and GC-MS. The intraspecies variations of the essential oil compositions were discussed using principal component analysis (PCA) and cluster analysis (CA). The antioxidant properties were evaluated DPPH-radical scavenging activity and β-carotene bleaching test. Results: The main components of Ammoides verticillata collective essential oil (Coll EO) were thymol (30.5%), carvacrol (23.2%), p-cymene (13.1%), limonene (12.5%) and terpinene-4-ol (12.3%). While roots of Carthamus caeruleus essential oil were dominated by carline oxide (86.2%). The chemical variability allowed the discrimination of two main Groups for both Coll EOs. A direct correlation between the altitudes, climate and the chemical compositions was evidenced. Ammoides verticulata and Carthamus caeruleus Coll Eos showed good antioxidant activity. In binary mixture, the interaction both Coll Eos and between oils rich of thymol and/or carvacrol with carlina oxide produced the best synergistic effects, compared to individual essential oils and the synthetic antioxidant (BHT). Conclusion: Ammoides verticillata and Carthamus caeruleus essential oil blends can be used as a natural food preservative and alternative to chemical antioxidants.

Therapeutic Potential of Citronella Essential Oil: A Review

2019 ◽  
Vol 16 (4) ◽  
pp. 330-339 ◽  
Author(s):  
Ruchi Sharma ◽  
Rekha Rao ◽  
Sunil Kumar ◽  
Sheefali Mahant ◽  
Sarita Khatkar
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Environmental Protection Agency ◽  
Therapeutic Potential ◽  
Biological Properties ◽  
Toxic Encephalopathy ◽  
Practical Applications ◽  
Insect Repellents ◽  
Citronella Oil ◽  
Medicinal Value

Mosquito-borne diseases such as malaria, filariasis, chikunguniya, yellow fever, dengue and Japanese encephalitis are the major cause of remarkable morbidity and mortality in livestock and humans worldwide. Since ancient times, aromatic plants are used for their medicinal value. Essential oils derived from these plants may be used as effective alternatives/adjuvants in pharmaceuticals, biomedical, cosmetic, food, veterinary and agriculture applications. These oils have also gained popularity and interest for prevention and treatment of various disorders. However, several reports on adverse effects including skin eruption, contact artricaria or toxic encephalopathy in children are available for synthetic repellent in the literature. Thus, natural insect repellents like essential oils have been explored recently as an alternative. One such essential oil studied widely, is citronella oil, extracted mainly from Cymbopogon nardus. This essential oil has exhibited good efficacy against mosquitoes. It is a mixture of components including citronellal, citronellol, geraniol as major constituents contributing to various activities (antimicrobial, anthelmintic, antioxidant, anticonvulsant antitrypanosomal and wound healing), besides mosquito repellent action. Citronella essential oil is registered in US EPA (Environmental protection agency) as insect repellent due to its high efficacy, low toxicity and customer satisfaction. However, poor stability in the presence of air and high temperature limits its practical applications. Since specific knowledge on properties and chemical composition of oil is fundamental for its effective application, the present review compiles and discusses biological properties of citronella oil. It also sheds light on various formulations and applications of this essential oil.

Evaluation of antioxidant and antimicrobial activity of Ziziphora ‎clinopodiodes essential oil eluted at different times

2020 ◽  
Vol 16 ◽  
Author(s):  
Mojgan Alizadeh ◽  
Akram Arianfar ◽  
Ameneh Mohammadi
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Positive Control ◽  
Essential Oil Composition ◽  
Oil Composition ◽  
Citronellic Acid ◽  
Antimicrobial And Antioxidant Activity

Objective: Ziziphora clinopodioides is an edible medicinal plant belongs to the Labiatae family that widespread all over Iran. It used as culinary and also in cold and cough treatments in Iran. The aim of present work was to evaluate the effect of different timeframes during the hydrodistillation on essential oil composition, antimicrobial and antioxidant activity. Materials and Methods: The essential oil of Z. clinopodiodes was extracted via hydrodistillation with Clevenger apparatus. The fractions of essential oil were captured at 6 times from the beginning of the distillation: (10, 20, 60, 120, 180 and 240 min). The fractions of essential oil were analyzed by GC/MS and their antibacterial, antifungal and antioxidant activities were studied by Disk - well diffusion and DPPH methods respectively. Results: Six distillation times and whole essential oil were captured during the hydrodistillation. Essential oil yield dropped off significantly during distillation progressed (1.0% for 10 min and 0.025 for 240 min). 1,8 Cineol, Isomenthone, Pulegone, Piperitenone and Citronellic acid were major compounds in fractions and they were affected by distillation times. Pulegone was major compound in all of essential oils. In antioxidant activity assay, whole essential oil was stronger than was stronger than positive control and fractions of essential oil, because of higher levels of Isomenthone, Piperitenone and Citronellic acid. Strongest antimicrobial activity against S. aureus, E. coli and C. albicans was observed from 10 min fraction. Conclusion: Our results indicated that distillation time can create essential oils with specific properties and we can achieve to more efficient essential oil in short times.

Resolution-Associated Molecular Patterns (RAMPs) as Endogenous Regulators of Glia Functions in Neuroinflammatory Disease

2020 ◽  
Vol 19 (7) ◽  
pp. 483-494
Author(s):  
Tyler J. Wenzel ◽  
Evan Kwong ◽  
Ekta Bajwa ◽  
Andis Klegeris
Keyword(s):  
Molecular Mechanisms ◽  
Inflammatory Responses ◽  
Bioactive Lipids ◽  
Prothymosin Α ◽  
Neuroinflammatory Disease ◽  
Cellular Debris ◽  
Αb Crystallin ◽  
Endogenous Regulators ◽  
The Central Nervous System ◽  
Molecular Patterns

: Glial cells, including microglia and astrocytes, facilitate the survival and health of all cells within the Central Nervous System (CNS) by secreting a range of growth factors and contributing to tissue and synaptic remodeling. Microglia and astrocytes can also secrete cytotoxins in response to specific stimuli, such as exogenous Pathogen-Associated Molecular Patterns (PAMPs), or endogenous Damage-Associated Molecular Patterns (DAMPs). Excessive cytotoxic secretions can induce the death of neurons and contribute to the progression of neurodegenerative disorders, such as Alzheimer’s disease (AD). The transition between various activation states of glia, which include beneficial and detrimental modes, is regulated by endogenous molecules that include DAMPs, cytokines, neurotransmitters, and bioactive lipids, as well as a diverse group of mediators sometimes collectively referred to as Resolution-Associated Molecular Patterns (RAMPs). RAMPs are released by damaged or dying CNS cells into the extracellular space where they can induce signals in autocrine and paracrine fashions by interacting with glial cell receptors. While the complete range of their effects on glia has not been described yet, it is believed that their overall function is to inhibit adverse CNS inflammatory responses, facilitate tissue remodeling and cellular debris removal. This article summarizes the available evidence implicating the following RAMPs in CNS physiological processes and neurodegenerative diseases: cardiolipin (CL), prothymosin α (ProTα), binding immunoglobulin protein (BiP), heat shock protein (HSP) 10, HSP 27, and αB-crystallin. Studies on the molecular mechanisms engaged by RAMPs could identify novel glial targets for development of therapeutic agents that effectively slow down neuroinflammatory disorders including AD.

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