scholarly journals SARS-CoV-2 from Urban to Rural Water Environment: Occurrence, Persistence, Fate, and Influence on Agriculture Irrigation. A Review

Water ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 764
Author(s):  
Giuseppe Mancuso ◽  
Giulio Demetrio Perulli ◽  
Stevo Lavrnić ◽  
Brunella Morandi ◽  
Attilio Toscano
Keyword(s):  
Wastewater Treatment Plants ◽  
Water Environment ◽  
Virus Transmission ◽  
Current Treatment ◽  
The Novel ◽  
Rural Water ◽  
Treatment Technologies ◽  
Agriculture Irrigation ◽  
Surface Water Bodies ◽  
Novel Coronavirus

The novel coronavirus disease (COVID-19), originating from China, has rapidly crossed borders, infecting people worldwide. While its transmission may occur predominantly via aerosolization of virus-laden droplets, the possibility of other routes of contagion via the environment necessitates considerable scientific consideration. SARS-CoV-2 viral RNA has been detected in the feces of infected persons, and studies also have reported its occurrence in wastewater and surface water bodies. Therefore, water may be a possible route of virus outbreaks. Agricultural irrigation is the largest use of water globally, accounting for 70% of water use worldwide. Ensuring adequate water quality within irrigation practices is fundamental to prevent harm to plants and soils, maintain food safety, and protect public health. This review aims to gather information on possible SARS-CoV-2 transmission routes within urban and rural water environments, looking into the detection, persistence, and fate of SARS-CoV-2. Based on published literature, the effect of current treatment technologies in wastewater treatment plants (WWTPs) on SARS-CoV-2 inactivation has also been investigated. Preliminary research efforts that concentrated on SARS-CoV-2 indicate that the risk of virus transmission from the aquatic environment may currently be non-existent, although a few studies have reported the presence of SARS-CoV RNA in soils, whereas there are still no studies on the detection of SARS-CoV-2 in crops.

scholarly journals Coronavirus Disease 2019 (COVID-19): Future Challenges and Recommendations for Dental Settings

2021 ◽  
Vol 4 (11) ◽  
pp. RV1-RV5
Author(s):  
Najmus Sahar ◽  
Pradeep Tangade ◽  
Vikas Singh ◽  
Surbhi Priyadarshini ◽  
Debashis Roy
Keyword(s):  
Health Care Workers ◽  
Preventive Measures ◽  
Clinical Manifestations ◽  
Virus Transmission ◽  
Review Article ◽  
The Novel ◽  
Medical Practitioners ◽  
Care Workers ◽  
Future Challenges ◽  
Novel Coronavirus

The novel coronavirus outbreak is a contagious disease affecting the countries around the world. The quick advancing nature of pandemic has gripped the entire community making it a public health emergency. Infection control preventive measures are necessary to prevent it from further spreading. Medical practitioners, health care workers and Dentists are at high risk of acquiring and transmission of infection. The virus transmission occurs through respiratory tract, aerosols and droplets. Clinical manifestations of virus vary from mild to severe sickness. This review article mainly emphasizes on all the information collected to date on the virus, and future recommendations for dental settings to manage the further spread of this virus.

scholarly journals Brief Report of Guidelines and Protocols for the Management of COVID-19

2020 ◽  
Vol 3 (2) ◽  
pp. 124-133
Author(s):  
Fabricia Oliveira Oliveira ◽  
Larissa Moraes dos Santos Fonseca ◽  
Roberto Badaró ◽  
Bruna Aparecida Souza Machado
Keyword(s):  
Management Strategies ◽  
Virus Transmission ◽  
The Novel ◽  
Data Flows ◽  
The World ◽  
Control And Prevention ◽  
Novel Coronavirus ◽  
Guidelines And Recommendations ◽  
The Impact ◽  
Coordinate Data

In less than a year, the novel coronavirus rapidly changed the world scenario. To dealing with the fast spread of the disease, health associations coordinate data flows and issue guidelines to better mitigate the impact of the threat. Also, scientific groups around the world are working to ensure that all information about the mechanisms of the virus, transmission, and disease clinics is updated as the disease progresses. The objective of this study was to present the guidelines and recommendations for preventing, management strategies, clarifications about pandemics disinformation, and diagnosing COVID-19 infection in human specimens adopted from the main health centers and institutions in the world, such as WHO and Centers for Disease Control and Prevention (CDC). It is important to highlight that the rapid and effective enforcement of existing international and national action plans, as well as parallel review and improvisation, is facilitating the affected countries to contain transmission and possibly delay the peak of outbreak and mortality.

scholarly journals Impacts of Social and Economic Factors on the Transmission of Coronavirus Disease 2019 (COVID-19) in China

2020 ◽  
Author(s):  
Yun Qiu ◽  
Xi Chen ◽  
Wei Shi
Keyword(s):  
Socioeconomic Factors ◽  
Transmission Rate ◽  
Virus Transmission ◽  
The Novel ◽  
Virus Spread ◽  
Government Response ◽  
Machine Learning Approach ◽  
The Rich ◽  
Novel Coronavirus

AbstractThis paper examines the role of various socioeconomic factors in mediating the local and cross-city transmissions of the novel coronavirus 2019 (COVID-19) in China. We implement a machine learning approach to select instrumental variables that strongly predict virus transmission among the rich exogenous weather characteristics. Our 2SLS estimates show that the stringent quarantine, massive lockdown and other public health measures imposed in late January significantly reduced the transmission rate of COVID-19. By early February, the virus spread had been contained. While many socioeconomic factors mediate the virus spread, a robust government response since late January played a determinant role in the containment of the virus. We also demonstrate that the actual population flow from the outbreak source poses a higher risk to the destination than other factors such as geographic proximity and similarity in economic conditions. The results have rich implications for ongoing global efforts in containment of COVID-19.

scholarly journals Modeling on Wastewater Treatment Process in Saudi Arabia: a perspective of Covid-19

2021 ◽  
Author(s):  
Zico Meetei Mutum ◽  
Abdullah A Ahmadini ◽  
Ahmed Msmali Hussein ◽  
Yaspal Raghav Singh
Keyword(s):  
Saudi Arabia ◽  
Wastewater Treatment ◽  
Global Economy ◽  
Wastewater Treatment Plants ◽  
Gaussian Model ◽  
The Novel ◽  
Wastewater Treatment Process ◽  
Virus Removal ◽  
Novel Coronavirus ◽  
Log Normal

The novel coronavirus diseases (COVID-19) has resulted in an ongoing pandemic affecting the health system and devastating impact on global economy. The virus has been found in human feces, in sewage and in wastewater treatment plants. We highlight the transmission behavior, occurrence, and persistence of coronavirus in sewage and wastewater treatment plants. Our approach is to follow in the process of identifying a coronavirus hotspot through existing wastewater plants in major cities of Saudi Arabia. The mathematical distributions including log-normal distribution, Gaussian model and susceptible- exposed-infection-recovered- (SEIR) model are adopted to predict the coronavirus load in wastewater plants. This paper highlights not only the potential virus removal techniques from wastewater treatment plants but also to facilitate tracing of SARS-CoV-2 virus in human through wastewater treatment plants.

scholarly journals Pediatric Acute Respiratory Distress Syndrome (PARDS) On Pediatric COVID-19 Patients

2021 ◽  
Vol 1 (2) ◽  
pp. 147-157
Author(s):  
Siti Rahmah ◽  
Lalu Wahyu Alfian Muharzami ◽  
Lastri Akhdani Almaesy ◽  
Putri Nurhayati ◽  
Ridha Sasmitha A
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Virus Transmission ◽  
The Novel ◽  
Handling Technique ◽  
The Difference ◽  
One Year ◽  
Novel Coronavirus

At the end of 2019, there was a pandemic happening in the world, called the novel Coronavirus disease-19 (COVID-19). Various spectrums of disease from COVID-19, one of which is ARDS. The incidence of COVID-19 in children is not as much as in adults. However, in children under one year of age it can get worse. The main characteristic of worsening infection is the occurrence of ARDS.  Objective: To find out the best treatment for PARDS in COVID-19 patients. Method: The writing of this article uses various sources from scientific journals to government guidelines and related institutions. Search articles using the keywords “Acute Respiratory Distress Syndrome”, “ARDS”, “Pediatric Respiratory Distress Syndrome”, “PARDS”, and “PARDS on COVID-19” Result and Discussion: PARDS was defined based on PALICC in 2015. Pathophysiology of PARDS in COVID-19 patients is still unclear. However, there is a theory that explains the way SARS-Cov-2 enters cells, namely through membrane fusion, giving rise to ARDS. The difference in handling PARDS for COVID-19 patients is that the handling technique is more alert to the risk of aerosols. Conclusions: There are differences in the handling of PARDS for COVID-19 patients in the technique by reducing the risk of virus transmission by preventing leakage when using a ventilator and using a bacterial/virus filter, as well as rescuers and staff using complete PPE during the procedure.

scholarly journals Ophthalmological aspects of coronavirus infections

2021 ◽  
Vol 14 (1) ◽  
pp. 7-14
Author(s):  
V. V. Neroev ◽  
T. N. Kiseleva ◽  
E. K. Eliseeva
Keyword(s):  
Respiratory System ◽  
Early Stage ◽  
Clinical Sample ◽  
Virus Transmission ◽  
Detection Methods ◽  
The Novel ◽  
Molecular Tests ◽  
Ocular Disorders ◽  
Coronavirus Infection ◽  
Novel Coronavirus

The novel coronavirus infection (COVID-19) caused by SARS-CоV-2 virus, may lead to ocular diseases besides affecting the respiratory system. Cororonavirus infection may be transmitted not only through the respiratory system but also through the conjunctiva. The review article summarizes the data on the origin and variants of coronaviruses that infect humans, as well as on SARS-CоV-2 structures. Literature data on prospects of molecular diagnostics of the disease, coronavirus type detection methods, clinical sample types and duration of the disease before it is diagnosed are discussed. The data on the relationship between the coronavirus infection and conjunctivitis are given. Molecular tests of the tear and conjunctival swabs were used to diagnose the coronavirus infection independently of whether symptoms of ocular disorders were present. The real-time reverse-transcription of RNA polymerase chain reaction (PCR) was the most informative method for diagnosis of SARS-CоV-2 in the early stage of COVID-19 (until the 9th day). The presence of SARS-CоV-2 in the tear fluid and conjunctival swabs indicates the need for safety measures to prevent virus transmission through the ocular surface, including protective goggles to be worn by healthcare workers. Since side effects in the eye may appear, COVID-19 patients with visual impairment who received etiotropic or pathogenetic treatment are advised to consult an ophthalmologist.

scholarly journals Conducting Translational Gastrointestinal Research in the Era of COVID-19

2020 ◽  
Vol 14 (12) ◽  
pp. 1759-1764
Author(s):  
Shadi Nayeri ◽  
Margaret Walshe ◽  
Sun-Ho Lee ◽  
Melissa Filice ◽  
Stella Rho ◽  
...  
Keyword(s):  
Translational Research ◽  
Virus Transmission ◽  
World Health ◽  
The Novel ◽  
Research Activities ◽  
Global Pandemic ◽  
Potential Risks ◽  
Global Catastrophe ◽  
Novel Coronavirus ◽  
Health Organization

Abstract Spread of the novel coronavirus SARS-CoV-2 has resulted in a global pandemic that is affecting the health and economy of all World Health Organization [WHO] regions. Clinical and translational research activities have been affected drastically by this global catastrophe. In this document we provide a suggested roadmap for resuming gastrointestinal translational research activities, emphasising physical distancing and use of personal protective equipment. We discuss modes of virus transmission in enclosed environments [including clinical workplaces and laboratories] and potential risks of exposure in the endoscopy environment for research staff. The proposed guidelines should be considered in conjunction with local institutional and government guidelines so that translational research can be resumed as safely as possible.

scholarly journals SARS-CoV-2 and COVID-19: From the Bench to the Bedside

2020 ◽  
Vol 100 (4) ◽  
pp. 1455-1466 ◽  
Author(s):  
Stefano Romagnoli ◽  
Adriano Peris ◽  
A. Raffaele De Gaudio ◽  
Pierangelo Geppetti
Keyword(s):  
Disease Progression ◽  
Respiratory Illness ◽  
The United States ◽  
Current Treatment ◽  
Clinical Syndrome ◽  
The Novel ◽  
Treatment Uncertainties ◽  
Novel Coronavirus ◽  
Pulmonary Microcirculation ◽  
Degrees Of Severity

First isolated in China in early 2020, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the novel coronavirus responsible for the ongoing pandemic of Coronavirus Disease 2019 (COVID-19). The disease has been spreading rapidly across the globe, with the largest burden falling on China, Europe, and the United States. COVID-19 is a new clinical syndrome, characterized by respiratory symptoms with varying degrees of severity, from mild upper respiratory illness to severe interstitial pneumonia and acute respiratory distress syndrome, aggravated by thrombosis in the pulmonary microcirculation. Three main phases of disease progression have been proposed for COVID-19: an early infection phase, a pulmonary phase, and a hyperinflammation phase. Although current understanding of COVID-19 treatment is mainly derived from small uncontrolled trials that are affected by a number of biases, strong background noise, and a litany of confounding factors, emerging awareness suggests that drugs currently used to treat COVID-19 (antiviral drugs, antimalarial drugs, immunomodulators, anticoagulants, and antibodies) should be evaluated in relation to the pathophysiology of disease progression. Drawing upon the dramatic experiences taking place in Italy and around the world, here we review the changes in the evolution of the disease and focus on current treatment uncertainties and promising new therapies.

scholarly journals The lockdown of Hubei Province causing different transmission dynamics of the novel coronavirus (2019-nCoV) in Wuhan and Beijing

2020 ◽  
Author(s):  
Xinhai Li ◽  
Xumao Zhao ◽  
Yuehua Sun
Keyword(s):  
Virus Transmission ◽  
Control Policy ◽  
Hubei Province ◽  
Control Measures ◽  
Capital City ◽  
Transmission Dynamics ◽  
The Novel ◽  
Real Situation ◽  
Seir Model ◽  
Novel Coronavirus

AbstractBackgroundAfter the outbreak of novel coronavirus (2019-nCoV) starting in late 2019, a number of researchers have reported the predicted the virus transmission dynamics. However, under the strict control policy the novel coronavirus does not spread naturally outside Hubei Province, and none of the prediction closes to the real situation.Methods and findingsWe used the traditional SEIR model, fully estimated the effect of control measures, to predict the virus transmission in Wuhan, the capital city of Hubei Province, and Beijing. We forecast that the outbreak of 2019-nCoV would reach its peak around March 6±10 in Wuhan and March 20±16 in Beijing, respectively. The infectious population in Beijing would be much less (only 0.3%) than those in Wuhan at the peak of this transmission wave. The number of confirmed cases in cities inside Hubei Province grow exponentially, whereas those in cities outside the province increase linearly.ConclusionsThe unprecedented province lockdown substantially suspends the national and global outbreak of 2019-nCoV.

Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Lung Cells ◽  
The Novel ◽  
High Modulation ◽  
Main Protease ◽  
The World ◽  
Novel Coronavirus ◽  
Viral Receptors ◽  
Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

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