scholarly journals GAMBARAN KADAR SERUM SERUM GLUTAMIC OXALOACETIC TRANSAMINASE (SGOT) PADA PEROKOK AKTIF USIA > 40 TAHUN

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Vani Y. Lomanorek ◽  
Youla A. Assa

Abstract: Smoking has become habit and lifestyle for most of the people in daily life. Negative effects of smoking are abundant and no limit at all. Three dangerous compounds in cigarette could cause damage to liver and heart. When liver and heart cells damaged, Serum Glutamic Oxaloacetic Transaminase (SGOT) enzyme releases in blood and became an indicator of liver and heart damage. The purpose of this study was to identify the level of SGOT serum of smokers aged > 40 years old. Twenty eight smokers were eligible to this criteria and participated in this study. Cross sectional design with a descriptive method was employed in this study. Sanples were analysed in laboratory for SGOT serum levels. Research results showed that all respondents participated in the present study had a normal serum SGOT. It can be concluded that serum SGOT level of > 40 years old smokers in Kolombo village, West Bitung 2 were all normal.Keywords: serum SGOT level, smoker, age > 40 yearsAbstrak: Merokok sudah menjadi kebiasaan dan gaya hidup bagi sebagian orang dalam kehidupan sehari-hari. Dampak negatif dari menghisap rokok sangat banyak dan tidak terbatas. Tiga zat berbahaya utama yang terdapat dalam rokok dapat menyebabkan kerusakan pada organ hati dan jantung. Saat sel-sel hati dan jantung mengalami cedera sel, enzim Serum Glutamic Oxaloacetic Transaminase (SGOT) akan dilepaskan ke dalam darah dan menjadi penanda adanya gangguan pada hati dan jantung. Tujuan dari penelitan untuk mengetahui gambaran kadar serum SGOT pada perokok aktif usia > 40 tahun. Dua puluh delapan orang yang telah memenuhi kriteria inklusi berpartisipasi dalam jenis penelitian deskriptif dengan pengamatan sewaktu (cross-sectional). Dari hasil pemeriksaan laboratorium didapatkan semua responden memiliki kadar serum SGOT yang normal. Berdasarkan hasil penelitian, dapat disimpulkan bahwa gambaran kadar serum SGOT pada usia > 40 tahun di Desa Kolombo lingkungan 4 RT 4, Kecamatan Maesa Kelurahan Bitung Barat 2 semua berada dalam batas normal.Kata kunci: kadar serum SGOT, perokok aktif, usia > 40 tahun

2021 ◽  
Vol 331 ◽  
pp. 02022
Author(s):  
Novia Wirna Putri ◽  
Septia Pristi Rahmah ◽  
Defriman Djafri ◽  
Irene Sandra Olivia ◽  
Ulfah Winanda Putri

The waste generation of Padang City at the Final Processing Site (TPA) is 495.50 tons/day, and the amount of unmanaged waste is 62.42 tons/day, of which 40% is plastic waste. Efforts to reduce the use of plastic bags have begun in Padang, referring to Perwaliko number 36 of 2018. Shopping centers and modern stores must use plastic shopping bags that meet SNI no later than December 31, 2020, especially in various retail and contemporary shopping centers. This study aimed to analyze the relationship between the effectiveness of plastic use policies and the decrease in the use of plastic bags in people who shop at modern retailers in Padang City. This type of research is quantitative with a cross-sectional design. The number of samples is 116 respondents who shop at modern shopping centers, namely Matahari Dept. Store, Food Mart Padang, Ramayana Padang and SPAR Padang. Data analysis used univariate and bivariate analysis. The results showed that 46.6% of respondents stated that the plastic bag policy was not adequate, and 46.6% of respondents stated that there was no reduction in plastic bags. There is a significant relationship between the effectiveness of the plastic bag policy and the decrease in the use of plastic bags in the people of Padang City (p=0,029). With this paid plastic bag policy, government, retailers, and the public will be more concerned with the environment.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Hendrika N. C. Dewi ◽  
Michaela E. Paruntu ◽  
Murniati Tiho

Abstract: Cigarette are the most cause of death around the world. Smoking cigarrete is harmful to the organs because it contains many toxic chemical that can stimulate inflammatory process. Smoking cigarrete is a risk factors for heart disease and chronic pulmonary disease (COPD). C-reactive protein (CRP) are a non spesific inflammatory marker that can elevated in both local and systemic disease. Beside biomarker, CRP also use as prognostic marker for inflammation. The purpose of this study was to identify the level of serum CRP of smokers aged >40 years old. Twenty eight smokers were eligible to this criteria and participated in this study. Cross-sectional design with a descriptive method was employed in this study. Sampels were analysed in laboratory for serum CRP levels. The results showed that 23 subjects (82%) had normal (negatif) serum CRP level and five subjects (18%) had positive serum CRP level. It can be concluded that serum CRP level of >40 years old smokers in Kolombo village, west Bitung two were mostly in normal level.Keywords: c-reactive protein (crp), active smoker, at age >40 years oldAbstrak: Rokok menjadi salah satu penyebab kematian terbesar di dunia. Merokok membahayakan hampir semua organ tubuh karena mengandung berbagai bahan kimia berbahaya yang dapat merangsang proses peradangan dan merupakan faktor utama penyakit jantung dan penyakit paru obstruktif kronik (PPOK). C-Reactive Protein (CRP) merupakan petanda inflamasi non-spesifik yang meningkat pada penyakit lokal maupun sistemik. Selain biomarker CRP juga dijadikan sebagai penanda prognostik untuk inflamasi. Tujuan dari penelitian ini untuk mengetahui kadar CRP serum pada perokok berusia >40 tahun. Dua puluh delapan perokok memenuhi syarat untuk kriteria ini dan berpartisipasi dalam penelitian ini. Penelitian ini menggunakan desain cross-sectional dengan metode deskriptif. Kadar CRP serum sampel dianalisis di laboratorium. Hasil penelitian menunjukkan bahwa 23 subyek (82%) memiliki kadar CRP serum normal (negatif) dan lima subjek (18%) memiliki kadar CRP serum positif. Dapat disimpulkan bahwa kadar CRP serum perokok berusia >40 tahun di desa Kolombo, Bitung barat dua kebanyakan dalam kadar normal.Kata kunci: c-reactive protein (crp), perokok aktif, usia >40 tahun.


1993 ◽  
Vol 136 (3) ◽  
pp. 517-523 ◽  
Author(s):  
C. Goñez ◽  
A. Villena ◽  
G. F. Gonzales

ABSTRACT Serum levels of adrenal androgens were measured in children of both sexes living at sea level and at high altitude using a cross-sectional design. The levels were compared in relation to age at each altitude (150 m and 3400 m above sea level), and the first significant increase in mean levels compared with values at preceding ages was assessed and defined as adrenarche. A total of 118 boys and 95 girls aged 6–12 years living at low altitude and 95 boys and 104 girls aged 7–15 years living at high altitude, all of them attending public schools, were studied. Serum dehydroepiandrosterone, dehydroepiandrosterone sulphate and androstenedione were measured by radioimmunoassay and height and weight by standard anthropometric techniques. There were two significant increases in serum levels of adrenal androgens, the first observed in children between 6 and 8 years at sea level, and between 7 and 9 years at high altitude, and the second in children between 10 and 12 years at sea level and between 12 and 15 years at high altitude. Serum adrenal androgen levels increased earlier in children at sea level than at high altitude. It is concluded that adrenarche occurs later at high altitude than at sea level. Journal of Endocrinology (1993) 136, 517–523


2019 ◽  
Vol 26 (3) ◽  
pp. 118
Author(s):  
Mokhamad Anhar Dani ◽  
Rizki Pranadyan ◽  
Muhammad Yusuf ◽  
Budi Prasetyo

Objectives: To analyze the causes of post-caesarean section surgical site infection (SSI) at South Konawe Hospital, Southeast Sulawesi, Indonesia, between February and July 2017.Materials and Methods: Retrospective study using descriptive method with cross-sectional design from February to July 2017 in inpatient and outpatient wards at Obstetrics and Gynecology Outpatient Clinic, South Konawe Hospital. The population was the patients medical records.Results: There were nine cases (7.75%) from totally of 116 cases of caesarean section with SSI. Based on SSI type, there were four cases (44.4%) with superficial SSI and 5 cases (55.5%) with deeper classification of SSI. SSI was dominated by women of productive age with age 20-35 years in 66.6% case. The lowest BMI was 22 kg/m2 and the highest BMI was 41.5 kg/m2. Hemoglobin levels were higher than 11 g/dL (66.6%). The most surgical action to be performed was emergency operation in 8 cases (15.09%).Conclusion:Causal characteristics of SSI at South Konawe were age of 20-35 years, the lowest BMI of 22 kg/m2 and the highest BMI 41.5 kg/m2, hemoglobin levels higher than 11 g/dL, and the need of emergency operation. 


2019 ◽  
Vol 7 (23) ◽  
pp. 4053-4058
Author(s):  
Nurul Utami ◽  
Elmeida Effendy ◽  
Mustafa Amin

BACKGROUND: BDNF implies to the development of abnormal nerves and neurotransmission that occurred during the changes of cognitive functions. However, in determining initial diagnosis of schizophrenia, measurements focus on the presences of positive and negative symptoms, and general psychopathological features without concerning the BDNF serum, which involves in central nervous system as the main symptom of schizophrenia. AIM: To determine the relation of BDNF serum level to cognitive functions of schizophrenia patients based on sub-domain of Montreal Cognitive Assessment Indonesia Version (MoCA-Ina) METHODS: This study was carried out based on observational analysis with cross-sectional design study. The samples were collected by non-probability sampling and consecutive sampling by recruiting 65 of male schizophrenia patients at Prof. Dr. M. Ildrem Mental Hospital, Medan, North Sumatera, Indonesia. BDNF serum levels were analysed throughout quantitative sandwich enzyme immunoassay method, while the cognitive functions were conducted by performing the MoCA-Ina, which concern to attentions and concentrations, executive function, memory, languages, visuoconstructional abilities, numerical calculation, and orientation. RESULTS: The serum level of BDNF was accounted averagely for 27161.26, with 5350.37 of standard deviation. There was positive correlation with medium strength (r = 0.4 - < 0.6) in visuospatial function, attention (r = 0.437), and memory (r = 0.413). CONCLUSION: Relation between BDNF serum level and cognitive function occurred in visuospatial, attention and memory domains based on MoCA-Ina assessment.


2018 ◽  
Vol 3 (2) ◽  
pp. 11
Author(s):  
Lita Nafratilova ◽  
Yusrawati Yusrawati ◽  
Irza Wahi

Early Onset Preeclampsia (EO-PE) is preeclampsia that develops before 34 weeks 'gestation, caused by intrinsic factors, while Late Onset Preeclampsia (LO-PE) is preeclampsia that develops after 34 weeks' gestation due to extrinsic and maternal factors. There is an increased production of antiangiogenic factors (sFlt-1, s-Eng and PIGF) contribute to pathophysiology of preeclampsia.This study aims to measure the difference of sFlt-1, sEng, PIGF levels between EO-PE and LO-PE. This was an observational study with cross sectional design conducted at Dr. M. Djamil, TK Hospital. III dr. Reksodiwiryo and Biomedical Laboratory FK Unand Padang from August 2017 to August 2018. The sample of this study were 26 severe preeclampsia women : 13 (EO-PE)  and 13 (LO-PE), selected using consecutive sampling. Levels of sFlt-1, sEng, PIGF were examined using the enzyme-linked immunosorbent assay (ELISA) method. Statistical analysis was performed using unpaired t test and Mann-Whitney Test. Results shown that serum levels of sFlt-1 and sEng in (EO-PE)  were 9.51 ± 0.71 ng / L, 1.44 ± 0.06 ng / mL, 5.79 ± 0.42 ng / mL while in PEAL it was 8, 89 ± 0.78 ng / mL, 1.35 ± 0.14 ng / mL, 6.72 ± 0.76. There were a significant difference with a value of p <0.05. The conclusion of this study is that the levels of sFlt-1 and sEng are higher in (EO-PE)  than(LO-PE)and PIGF levels was lower in (EO-PE) compared to (LO-PE)


2019 ◽  
Vol 17 (2) ◽  
pp. 74-100
Author(s):  
Sabina Trif ◽  
Oana C Fodor

Humor is inherent to social interaction and research has mainly focused on the potential benefits of using humor at work. However, different types of humor exist and this study builds on the Job Demands-Resources Model (JD-R) to argue that aggressive humor in the workplace is a demand rather than a resource. Specifically, the study explores the association of aggressive humor and the intention to leave the organization manifested by the employees and the role of exhaustion as a potential explanatory mechanism. Moreover, the study explored the potential buffering role of the quality of leader-employee exchange (LMX) for the negative effects of aggressive humor. The study employed a cross-sectional design in order to test a moderated mediation model. Data were collected from 101 call-center operators and team leaders working in a multinational company. Our findings show indeed that aggressive humor in the workplace is predictive for exhaustion, which, in turn, predicts the employees’ intentions to leave the organization. Contrary to our expectation, the moderating role of LMX did not receive empirical support. Theoretical and practical implications are discussed.


Author(s):  
Sadhana A. Raina ◽  
Poorvi S. Jain ◽  
Manjusha M. Warhadpande

Background: India, a developing country, faces many challenges in rendering health needs to its countrymen. The influence of culture is seen in every discipline of health and medical practices, and dentistry is no exception. This study was performed to investigate the existence of myths and taboos in dentistry, to assess the variation of these myths across various demographic aspects and socio-economic status, to co-relate the existence of myths with the oral health of the subject and to impart education to the people regarding abolishing the myth as that will be a hindrance towards a healthy life in patients.  Methods: The study had a cross-sectional design, used a structured questionnaire and was conducted to assess the existence of dental myths and taboos and to determine its correlation with the OHIS index of the patients. Statistical analysis software SPSS V 16.0 was used. Descriptive & inferential statistical analysis was performed on categorical and continuous data. Chi-square, independent sample T tests and ANOVA test were used to compare the distribution of caries and OHI-S between different groups. P value less than 0.05 (p<0.05) was considered to be significant. Socioeconomic status was also calculated.Results: In the present study it was found that the there was almost an equal distribution of prevalence of myths in the educated as well as uneducated patients .Also the ratio of existence of myths was found higher in females as compared to males.Conclusions: Existence of myths and taboos regarding dental health has started decreasing among the urban population due to the widespread of awareness regarding dentistry.But still there is prevalence of some myths in the patients having primary education as compared to patients having secondary and tertiary education. If community is educated about proper prevention and cure, the myths relating dental concepts will vanish from the society and over all dental health status of the community will improve.


2021 ◽  
Vol 22 (1) ◽  
pp. 6-13
Author(s):  
Rini Andriani

The gadget utilization among preschoolers in connection with technological advances is known to have positive and negative effects on growth and development. This study aims to identify the overview of gadget utilization and its effect on growth and development in preschool children. An analytic survey with a cross-sectional design was conducted by filling out questionnaires carried out by parents. The anthropometric measurements and developmental assessments were carried out using Indonesia Developmental Pre-screening Questionnaire (IDPQ). A hundred children and their parents participated in this study. It was found that 82% of parents lent their gadgets, and 89% taught their children to use gadgets. There were similarities in gadget utilization between parents and children, namely watching videos (73% and 90%) and communicating (92% and 40.4%). The duration of the gadget utilization by children was high, 3.7±2.2 hours/day. However, no significant correlation in the analysis between the duration of smartphone usage and nutritional status (p: 0.599). In children with different IDPQ values, there was no significant difference in the duration of device usage (p: 0.991). It can concluded the duration of the gadget utilization in children carried out by their parents did not affect the growth and development of the children.


2021 ◽  
Vol 3 (1) ◽  
pp. 9-21
Author(s):  
Wirda Anggraini

Abstract—Pneumonia was an inflammation that occurs in the lungs accompanied by exudation and consolidation of microorganisms. In Indonesia, the prevalence of pneumonia continues to increase. Treatment of pneumonia uses antibiotic therapy. The use of antibiotics needs to be controlled by evaluating the quality of antibiotic use to prevent negative effects that can occur on patients, such as antibiotic resistance. The purpose of this study was to determine the quality of antibiotic use in pneumonia patients. This study did with observational method with cross-sectional design. The study was conducted in August-September 2019. Qualitative evaluations did with Gyssen method. The results of 35 medical record samples that fulfill the criteria showed that 21.43% of cases category 0; 16.67% of cases category I; 0% of cases category II C; 33.34% of cases in category II B; 4.76% of cases category II A; 0% of cases category III B; 0% of cases category III A; 0% of cases category IV D; 19.05% of cases category IV C; 4.76% of cases category IV B; 61.90% of cases category IV A; 0% of cases category V; 0% of cases category VI. Thus, rational cases (category I) were 21,43% and irrational cases (categories I-IV) were 78,57%.


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