scholarly journals Pemberian ekstrak daun cincau (Mesona palustris BL) oral meningkatkan jumlah sel β pankreas dan menurunkan gula darah puasa pada tikus putih (Rattus norvegicus) jantan galur Wistar diabetes

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Fatimah Zahra ◽  
Anak A.G. Budhiarta ◽  
Wimpie Pangkahila
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Treatment Group ◽  
Fasting Blood Glucose ◽  
Male Rats ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Pancreatic Cells ◽  
Post Test

Abstract: Grass jelly leaf is a traditional Indonesian beverage that is believed to be beneficial for our health. This study was carried out to observe the increased number of pancreatic  cells and the decreased fasting blood glucose in male Wistar rats with diabetes induced by streptozotocin (STZ). This was a pure experimental study with a post-test only control group design. Subjects were 36 male rats divided into 2 groups: the control group (P0), given glibenclamide dose 0.09 mg /200 g rat body weight and 2 ml aquadest as placebo; and the treatment group (P1), given glibenclamide 0.09 mg/200mg rat body weight and grass jelly leaf extract 54 mg/200 mg rat body weight. Pancreatic  cell count and blood glucose examination were performed after 28 days of treatment. The results showed that the number of pancreatic  cells in the treatment group (P1) was statistically higher than of the control group (P0) (56.72±5.644 vs 29.11±2.698 cells (P ≤0.001). In addition, the fasting blood glucose level of the treatment group (P1) was statistically lower than of the control group (P0) (79.50±37.75mg/dl vs 191.00±123.15mg/dl) (P <0.001). Conclusion: The administration of grass jelly extract increased pancreatic β cells and decreased fasting blood glucose level in diabetic male rats. Keywords: grass jelly extract, fasting blood sugar, pancreatic beta cells, diabetes mellitus Abstrak: Daun cincau atau grass jelly (Mesona palustris BL) merupakan bahan minuman tradisional Indonesia yang dipercaya bermanfaat untuk kesehatan. Penelitian ini dilakukan untuk mengetahui adanya peningkatan jumlah sel β pankreas dan penurunan kadar gula darah puasa pada tikus Wistar diabetes yang diinduksi streptozotocin (STZ). Jenis penelitian ialah eksperimental murni dengan post-test only control group design. Subyek penelitian ialah 36 ekor tikus putih jantan, dibagi menjadi 2 kelompok, yaitu: kelompok kontrol (P0) yang diberikan glibenklamid oral dosis 0,09 mg/200gr BB tikus dan 2 ml aquadest sebagai plasebo; dan kelompok perlakuan (P1) yang diberikan glibenklamid oral dosis 0,09 mg/200 gr BB tikus dan ekstrak daun cincau dosis 54 mg/200gr BB tikus. Penghitungan jumlah sel β pankreas dan pengukuran gula darah dilakukan setelah 28 hari perlakuan. Hasil penelitian menunjukkan bahwa kelompok perlakuan (P1) memiliki jumlah sel β pankreas yang secara statistik lebih tinggi dibandingkan kelompok kontrol (P0) (56,72±5,644 sel/lapang pandang vs 29,11±2,698 sel/lapang pandang) (P ≤0,001). Selain itu, kelompok perlakuan (P1) memiliki kadar gula darah puasa yang secara statistik lebih rendah dibandingkan kelompok kontrol (P0) (79,50±37,75 mg/dl vs 191,00±123,15 mg/dl) (P <0,001). Simpulan: Pemberian ekstrak daun cincau (Mesona palustris BL) meningkatkan jumlah sel β pankreas dan menurunkan kadar gula darah puasa pada tikus (Rattus novergicus) jantan galur Wistar diabetes.Kata kunci: ekstrak daun cincau, gula darah puasa, sel beta pankreas, diabetes melitus

scholarly journals Pengaruh Pemberian Aspartam terhadap Kadar Glukosa Darah Tikus Diabetes Melitus Diinduksi Aloksan

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Ega Purnamasari ◽  
Eti Yerizel ◽  
Efrida Efrida
Keyword(s):  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Diabetic Rats ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Post Test ◽  
Diabetes Melitus

AbstrakAspartam merupakan gula pengganti rendah kalori yang sering dikonsumsi oleh pengidap diabetes, tetapi keamanannya masih kontroversi. Intensitas rasa manis aspartam yang tinggi diduga dapat menurunkan kadar glukosa darah. Penelitian lain menyebutkan hasil metabolisme aspartam berupa asam aspartat dan fenilalanin dapat menjadi prekursor glukosa melalui glukoneogenesis. Tujuan penelitian ini ialah untuk mengetahui pengaruh pemberian aspartam terhadap kadar glukosa darah tikus diabetes melitus diinduksi aloksan. Penelitian ini adalah penelitian eksperimental dengan post-test only control group design. Sampel penelitian ini terdiri dari 20 ekor tikus Wistar jantan yang dibagi menjadi kelompok kontrol negatif (KN), kontrol positif (KP), perlakuan 1 (P1), perlakuan 2 (P2). Aloksan 150 mg/kgBB diinduksikan pada kelompok KP dan P2, aspartam 315 mg/kgBB diberikan pada kelompok P1 dan P2 selama 4 minggu. Kadar glukosa darah puasa diukur setelah 4 minggu menggunakan spektrofotometer. Hasil penelitian ini didapatkan rerata kadar glukosa darah puasa kelompok KN (88,39 mg/dL), KP (134,11 mg/dL), P1 (93,95 mg/dL), dan P2 (66,66 mg/dL). Analisis data dengan Uji ANOVA nilai p= 0,000 (p<0,05), terdapat perbedaan kadar glukosa darah puasa yang bermakna pada semua kelompok. Keimpulan penelitian ini adalah terdapat pengaruh pemberian aspartam terhadap penurunan kadar glukosa darah puasa tikus diabetes melitus diinduksi aloksan.Kata kunci: aspartam, kadar glukosa darah, diabetes melitus, aloksanAbstractAspartame is a low-calorie sugar substitute that is often consumed by people with diabetes, but the safety of aspartame is still controversial. The high intensity of aspartame sweetness could be expected to lower blood glucose levels. Other study said the results of the metabolism of aspartame such aspartic acids and phenylalanine which can be a precursor of glucose through gluconeogenesis. The purpose of this study was to determine the effect of aspartame on blood glucose levels of alloxan induced diabetic rats. This study is an experimental study with a post-test only control group design. Twenty male Wistar rats were divided into 4 groups: negative control (KN), positive control (KP), treatment 1 (P1), treatment 2 (P2). Alloxan 150 mg/kg body weight induced in KP and P2 groups, aspartame 315 mg/kg body weight administered on P1 and P2 groups for 4 weeks. Fasting blood glucose levels were measured after 4 weeks using a spectrophotometer. The results of this study, the mean fasting blood glucose levels KN group (88.39 mg/dL), KP (134.11 mg/dL), P1 (93.95 mg/dL), and P2 (66.66 mg/dL). Data were analyzed using ANOVA test, p-value=0.000 ( p<0.05 ), there are differences in fasting blood glucose levels were significant in all groups. The conclusions of this study is the provision of aspartame in alloxan induced diabetic rats can cause a decrease in blood glucose levels significantly.Keywords: aspartame, blood glucose levels, diabetes mellitus, alloxan

scholarly journals PENGARUH PELATIHAN THREE CORNER DRILL TERHADAP PENINGKATAN KELINCAHAN DAN POWER

2018 ◽  
Vol 6 (3) ◽  
Author(s):  
I Gede Agunk Teddy Pratama ◽  
Made Budiawan ◽  
I Nyoman Sudarmada
Keyword(s):  
Treatment Group ◽  
Muscle Power ◽  
T Test ◽  
Training Effect ◽  
Control Group ◽  
Test Results ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Quasi Experimental

Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan three corner drill terhadap kelincahan dan power otot tungkai. Jenis penelitian adalah quasi experimental dengan rancangan the non-randomized pretest-posttest control group design. Subjek penelitian yang digunakan siswa putra peserta ektrakurikuler sepak bola SMPN 2 Pekutatan. Data post-test kelincahan dan power otot tungkai pada kelompok perlakuan dan kelompok kontrol dianalisis dengan uji-t independent pada taraf signifikansi (α) 0,05 dengan bantuan program SPSS 16.0. Berdasarkan hasil uji-t independent didapatkan hasil : (1) untuk variabel kelincahan, hasil perbandingan kelompok perlakuan dan kontrol didapatkan nilai thitung = -2,948 , dengan nilai signifikansi 0,009, (2) untuk variabel power, hasil perbandingan kelompok perlakuan dan kontrol didapatkan nilai thitung = 3,176, dengan nilai signifikansi 0,005. Nilai signifikansi hitung lebih kecil dari nilai α (Sig < 0,05), dengan demikian hipotesis penelitian “pelatihan three corner drill berpengaruh terhadap peningkatan kelincahan dan power otot tungkai pada siswa putra peserta ektrakurikuler sepak bola SMPN 2 Pekutatan” diterima. Dari hasil analisis data dan pembahasan disimpulkan bahwa : (1) Pelatihan three corner drill berpengaruh terhadap peningkatan kelincahan pada siswa putra peserta ektrakurikuler sepak bola SMP Negeri 2 Pekutatan (2) Pelatihan three corner drill berpengaruh terhadap peningkatan power otot tungkai pada siswa putra peserta ektrakurikuler sepak bola SMP Negeri 2 Pekutatan. Kata Kunci : kelincahan, daya ledak, three corner drill The purpose of this research was to find out the effect of three corner drill training toward the increased agility and power muscle of legs. The type of research was a quasi-experimental and the design of research was the non-randomized pretest-posttest control group design. The subjects were man’s student football extracurricular participants of SMPN 2 Pekutatan. Agility and muscle power of legs posttest to the treatment group and the control group were analyzed by independent t-test at significance 0,05 with SPSS 16.0. Based on independent t-test results were showed : (1) to the agility variable, the comparison of the treatment and the control group values obtained t = -2,948, with a significance value of 0,009, (2) to muscle power of legs variable, the comparison of the treatment and the control group values obtained t = 3,176, with a significance value of 0,005. Calculated significance value smaller than the value of 0,05 (Sig < 0.05), thus the research hypothesis "three corner drill training affect the increased agility and muscle power of legs in football extracurricular participants of SMPN 2 Pekutatan " was received. From the analyzed and discussion were concluded that : (1) three corner drill training effect the increased agility in football extracurricular participants of SMPN 2 Pekutatan, (2) three corner drill training effect the increased muscle power of legs in football extracurricular participants of SMPN 2 Pekutatan. keyword : Agility, power, three corner drill

scholarly journals PELATIHAN PUKULAN BAYANGAN LEBIH BAIK DARI PADA PUKULAN BIASA DALAM MENINGKATKAN VO2MAX DAN DAYA TAHAN OTOT LENGAN PADA ATLET TINJU AMATIR KABUPATEN LOMBOK TENGAH (NTB)

2019 ◽  
Author(s):  
Khaerul Anam ◽  
I P G Adiatmika ◽  
I Putu Adiartha Griadhi ◽  
I Made Muliarta ◽  
Luh Putu Ratna Sundari ◽  
...  
Keyword(s):  
Treatment Group ◽  
Anaerobic Capacity ◽  
T Test ◽  
Control Group ◽  
Research Subjects ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Arm Muscles ◽  
Test Control

Boxing is the basic gesture for all martial arts, because all of them definitely use the shadow shot and common shot. These two types of shots are related each other because anaerobic capacity must go along with aerobic capacity.To attain the proper knowledge about the method of shadow shot and common shot in increasing VO2max for the endurance of arm muscles for boxer athletes in Central Lombok Regency. Research was experimental with pre-test and post-test control group design, this research wasconducted in Pertina Lombok Tengah Regency. The research subjects involved 15 people divided into two groups, 7 and 8 samples respectively. The control group given only shadow shot while treatment group given common shot. This training held 3 times a week in six weeks for both groups. The analyses data with independent t-test. Researcher found The endurance of arm muscles (p<0,05) that training in twu group his’not significant to VO2max (p>0,05).Keywords: Shadow blows, regular blows, Boxing, VO2max and Endurance of arm Muscl

scholarly journals The Use of New Control Card for Health Education about Chemotherapy Procedures for Patients

2017 ◽  
Vol 1 (1) ◽  
pp. 1-6
Author(s):  
Tumini Tumini
Keyword(s):  
Treatment Group ◽  
Health Education ◽  
Experimental Research ◽  
Control Group ◽  
Knowledge Level ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
One Stop ◽  
And Control

In every stage of long and complex chemotherapy procedure, of course, it could confuse patients. The purpose of this queasy experimental research was to analyze the effect of education from nurses about chemotherapy procedure on patient's knowledge level toward the use of new card at one-stop oncology poly (POSA (Poli Onkologi Satu Atap)) of Dr. Soetomo Hospital, Surabaya, by using "pre-test post-test with control group design". The subjects were divided into two groups: treatment group that was given the education in using new cards and control group that was given the education in using old cards. The treatment group underwent the increase knowledge of general chemotherapy procedures, meanwhile, the control group did not undergo any increase. Keywords: Chemotherapy procedures, Knowledge, Patients, Education

scholarly journals Efek Suplemen Bawang Putih terhadap Kadar Kolesterol dan Trigliserida pada Tikus Wistar yang Diberi Diet Tinggi Minyak Sawit

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Mulfa Satria Asnel ◽  
Husnil Kadri ◽  
Dessy Arisanty
Keyword(s):  
Treatment Group ◽  
Palm Oil ◽  
Diet Group ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Cholesterol Levels ◽  
Post Test ◽  
Ad Libitum ◽  
Test Control

AbstrakMinyak kelapa sawit banyak mengandung asam lemak jenuh yang diduga dapat menyebabkan kolesterol dan trigliserida meningkat. Tujuan penelitian ini adalah mengetahui efek suplemen bawang putih terhadap kadar kolesterol dan trigliserida tikus galur wistar yang diberi diet tinggi minyak sawit. Ini merupakan penelitian eksperimental dengan randomized post test control group design. Subjek penelitian adalah 15 ekor tikus Wistar jantan yang dibagi menjadi tiga kelompok, yaitu kelompok diet standar ad libitum, kelompok diet tinggi minyak sawit dan kelompok perlakuan (diet tinggi minyak sawit+suplemen bawang putih). Masing-masing kelompok terdiri dari lima ekor tikus. Pemberian minyak sawit dengan kadar 3 ml/15 gram pakan standar diberikan kepada kelompok diet tinggi minyak sawit dan kelompok perlakuan selama empat minggu. Pemberian suplemen bawang putih (dosis 3,6 mg/200 mgBB tikus) diberikan kepada kelompok perlakuan selama empat minggu. Kadar kolesterol pada kelompok diet tinggi minyak sawit adalah 109 ± 2,76 mg/dl dan pada kelompok perlakuan adalah 107 ± 3,09 mg/dl. Kadar trigliserida pada kelompok diet tinggi minyak sawit adalah 84 ± 4,27 mg/dl, pada kelompok perlakuan adalah 83 ± 6,02 mg/dl. Tidak terdapat perbedaan yang bermakna kadar kolesterol dan trigliserida antara kelompok diet tinggi minyak sawit dengan kelompok perlakuan. Pada kelompok diet standar ad libitum dengan kelompok diet tinggi minyak sawit maupun antara kelompok diet standar ad libitum dengan kelompok perlakuan terdapat perbedaan yang bermakna pada kadar kolesterol dan trigliserida.Kata kunci: minyak sawit, suplemen bawang putih, kolesterol, trigliseridaAbstractPalm oil contains a lot of saturated fatty acids and it is supposed to cause increased cholesterol and triglyceride levels. The objective of this study was to determine the effect of garlic supplements on cholesterol levels and triglyceride at wistar strain rats which were fed in high diet palm oil. This study is a randomized experimental study with post-test control group design. The subjects were 15 male wistar rats were divided into three groups, standard ad libitum diet group, high diet palm oil group and the treatment group (high diet palm oil+ garlic supplement). Each group consists of five rats. Provision of palm oil with high levels of standard 3 ml/15 grams of feeding given to the high diet palm oil group and the treatment group during the four weeks. Garlic supplement (dose 3.6 mg/200 mgweight rat) was given to the treatment group for four weeks. Cholesterol levels in the high diet palm oil group was 109 ± 2,76 mg/dl in the treatment group was 107 ± 3,09 mg/dl. The levels of triglycerides in the high diet palm oil group was 84 ± 4,27 mg/dl and in the treatment group was 83 ± 6,02 mg/dl. There was no significant difference the levels of cholesterol and triglycerides between the high diet palm oil group with the treatment group. Between the standard ad libitum diet group with the high diet palm oil group and between the standard ad libitum diet group with the treatment group show there were significant differences in the levels of cholesterol and triglycerides.Keywords: palm oil, garlic supplement, cholesterol, triglyceride

scholarly journals The Potential of Strawberry, Rome Beauty Apple, and New Combination on Fasting Blood as Supporting Diet Therapy in Patients with Type II Diabetes Mellitus

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Niken Yuliwati ◽  
Riezky Faisal Nugroho
Keyword(s):  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Type Ii ◽  
Control Group Design ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Post Test ◽  
Post Hoc ◽  
Diabetes Melitus

Strawberries (Fragaria x ananassa) and Rome beauty apples (Malus sylvestris) contain high antioxidants to reduce oxidative stress and improve the glycemic response with diabetes mellitus (DM) type II. This study aimed to analyze the effect of strawberries, Rome beauty apples, and their combination to decrease fasting blood glucose levels of type II DM patients. This experimental research used a randomized pre-post-test with a control group design. Subjects were 44 patients divided into four groups: K (control, not given the fruit), P1 (strawberries 200 g/day), P2 (apples 300 g/day), and P3 (the combination strawberries 100 g/day, apples 150 g/day) for 14 days in February–March 2019 in Surakarta. The inclusion criteria were DM patients aged 40–55 years who received oral antidiabetic drug therapy. Exclusion criteria were type II DM patients who, based on the doctor's diagnosis, had complications such as gastritis, hypertension, chronic renal failure, heart disease, liver disease, stroke, cancer, patients with consumption of antioxidant supplements. Mean of blood glucose level on K (149.82±39.125), P1 (141.00±38.079), P2 (128.73±31.841), and P3 (177.73±50.176). Analysis paired t test results showed a significant difference between before and after treatment (p=0.045). To find out which group was the most meaningful, the Bonferroni post hoc test. Decrease of fasting blood glucose levels with group K (−10.55, p>0.05), P1 (−30.18, p<0.05), P2 (40.27, p<0.05), and P3 (−32.91, p<0.05). ANOVA test was used to analyze, and the post hoc Bonferroni test with a control comparison was performed, resulting in p=0.028, in P2 and p>0.05 in P1 and P3. In conclusion, strawberries, Rome beauty apples, and their combination significantly decreased fasting blood glucose levels of type II DM patients, with the highest and most significant decrease in Rome beauty apples. POTENSI STROBERI, APEL ROME BEAUTY, DAN KOMBINASI BARU TERHADAP GULA DARAH PUASA SEBAGAI PENUNJANG TERAPI DIET PADA PASIEN DIABETES MELITUS TIPE IIStroberi (Fragaria x ananassa) dan apel Rome beauty (Malus sylvestris) mengandung antioksidan tinggi untuk mengurangi stres oksidatif dan memperbaiki respons glikemik pada diabetes melitus (DM) tipe II. Tujuan penelitian adalah menganalisis pengaruh buah stroberi, apel Rome beauty, dan kombinasinya terhadap penurunan kadar glukosa darah puasa pasien DM tipe II. Jenis penelitian eksperimen dengan rancangan randomized pre-post-test dengan control group design. Subjek penelitian 44 pasien yang dibagi empat kelompok, yaitu K (kontrol tidak diberi buah), P1 (stroberi 200 g/hari), P2 (apel Rome beauty 300 g/hari) dan P3 (kombinasi stroberi 100 g/hari dan apel 150 g/hari) selama 14 hari pada bulan Februari–Maret 2020 di Surakarta. Kriteria inklusi adalah pasien DM usia 40–55 tahun yang mendapat terapi obat antidiabetik oral. Kriteria eksklusi adalah pasien DM tipe II yang berdasar atas diagnosis dokter mengalami komplikasi seperti mag, hipertensi, gagal ginjal kronik, penyakit jantung, penyakit hati, strok, kanker, dan pasien dengan konsumsi suplemen antioksidan. Kadar glukosa darah rerata pada K (149,82±39,125), P1 (141,00±38,079), P2 (128,73±31,841), dan P3 (177,73±50,176). Hasil analisis paired t test menunjukkan terdapat perbedaan yang signifikan antara sebelum dan sesudah perlakuan (p=0,045). Untuk mengetahui kelompok mana yang paling bermakna, dilakukan Uji Post Hoc Bonferroni. Penurunan kadar glukosa darah puasa pada K (−10,55; p>0,05), P1 (−30,18; p<0,05), P2 (−40,27; p<0,05), dan P3 (−32,91; p<0,05). Analisis dilakukan dengan uji ANOVA dan Uji Post Hoc Bonferroni dengan perbandingan kontrol menghasilkan p=0,028 pada P2 serta p>0,05 pada P1 dan P3. Simpulan, pemberian stroberi, apel Rome beauty, dan kombinasinya signifikan menurunkan kadar glukosa darah puasa pasien DM tipe II dengan penurunan tertinggi dan bermakna pada apel Rome beauty.

scholarly journals Pengaruh Pendidikan Gizi terhadap Sikap, Asupan Zat Gizi Makro, dan Air pada Anggota Pramuka

2020 ◽  
Vol 3 (2) ◽  
pp. 60
Author(s):  
Farida Farida ◽  
Hesti Permata Sari ◽  
Afina Rachma Sulistyaning ◽  
Ibnu Zaki
Keyword(s):  
Treatment Group ◽  
Control Group ◽  
Attitude Score ◽  
Nutritional Education ◽  
Control Group Design ◽  
Group Design ◽  
Before And After ◽  
Post Test ◽  
Quasi Experimental ◽  
Test Control

<p><em>The study was aimed to analyze the effect of nutritional education on attitude changes and increased of macronutrients and water intake in scout teenagers. The study was quasi-experimental with pre- and post-test control group design. The treatment group was given nutritional education four times during one month. Pre-test was conducted a week before intervention and post-test was conducted a week after intervention. Subjects were all members of Saka Bhayangkara and Saka Wira Kartika Scout. The result showed that nutritional education was significant improved median value of attitude score and increased (p &lt;0,05). macronutrients intake in treatment group. The average of macronutrients intake in treatment group, before and after intervention were 1137,8±178,7 Kcal and 1490,4± 206,6 Kcal/day for energy; 40,4 ± 9,8 g/day and 60,8 ± 9,3g/day for protein; 38,5 ± 12,6 g/day and 59,3 ± 9,4 g/day for fat; 155,6 ± 29,5 g/day and 177,6 ± 33,5 g/day for carbohydrates; 782,4±347,7 mL and 834,6±383,2 mL for water. Nutritional education improved nutrition attitudes and increased macro-nutrient intake among scout.</em></p>

scholarly journals Pengaruh Pemberian Minuman Fungsional Terhadap Penurunan Kadar Glukosadarah Puasa Pada Penderita Diabetes Melitus

2019 ◽  
Vol 4 (2) ◽  
pp. 114
Author(s):  
Tutut Zikra Anjani ◽  
Suhaema Suhaema ◽  
Fifi Lutfiah ◽  
Ni Ketut Sri Sulendri
Keyword(s):  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Female Gender ◽  
Simple Random Sampling ◽  
Control Group ◽  
Risk Category ◽  
Control Group Design ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Post Test

Indonesia is currently the fourth country with the largest number of DM patients in the world. Functional food is beneficial for the health of DM patients, for example bananas and soybeans. Kepok bananas contain dietary fiber inulin and antioxidants (β carotene). Soybeans contain isoflavones, fiber, and proteins in the form of amino acids arginine and glycine. This study aims to look at the effect of giving functional drinks a mixture of soybean and banana milk on decreasing fasting blood glucose levels in type II DM patients. Type of Quasy-experimental research with pre test and post test with control group design. Subjects were taken using the Simple Random Sampling method and the subjects involved until the end of the study were 26 people. The intervention was carried out for 14 days and given as much as 330 ml. The equality of the subject characteristics of the two groups was analyzed using the chy squere test, and the effect of giving intervention materials on decreasing blood glucose levels was tested by independent t test. The results of the study were characteristics (84.6%) aged 50-60 years, (53.8%) female gender, (57.1%) having a family history of disease, 58.4% using glibenclamide anti-hyperglycemic drugs and BMI average in the risk category. . Result Δ It is known that there is an effect of giving functional drinks on decreasing fasting blood glucose levels where the average change is 11.5 mg / dl (p = 0.03). 

scholarly journals PENGARUH PEMBERIAN SAGU DIBANDING NASI TERHADAP BERAT BADAN TIKUS WISTAR

e-CliniC ◽  
2013 ◽  
Vol 3 (2) ◽  
Author(s):  
Eny A. Watumlawar ◽  
Sarah M. Warouw ◽  
Stefanus Gunawan
Keyword(s):  
Body Weight ◽  
Wistar Rats ◽  
Wilcoxon Test ◽  
Control Group ◽  
Increase Body Weight ◽  
Control Group Design ◽  
Tissue Mass ◽  
Group Design ◽  
Post Test ◽  
Male Wistar Rats

Abstract: Weight is one measure that gives description of the tissue mass including body fluids. Weight change is nfluenced by nutriment consumption. Sago contains high carbohydrates that can increase body weight. This study aimed to obtain the effect of sago compared to rice to body weight of wistar rats. This was a random laboratory experimental pre-post test with control group design. Subjects were male wistar rats, aged 5-6 months. The rats were divided in two groups: rice group as control and sago group. Sago was cooked in papeda form as much as 75 g of dried sago and 300 mL water. The rats were fed for 2 weeks. Data were analyzed by using the Wilcoxon test. The results showed that the sago group showed an increase of body weight significantly (p=0,001) meanwhile the rice group lose body weight significantly (p=0,001). Conclusion: Sago can increase body weight of wistar rats significantly.Keywords: body weight, sago, riceAbstrak: Berat badan merupakan salah satu ukuran yang memberikan gambaran massa jaringan termasuk cairan tubuh. Salah satu yang memengaruhi berat badan yaitu dengan mengonsumsi makanan bergizi. Sagu memiliki kandungan karbohidrat (pati) yang besar dan dapat meningkatkan berat badan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian sagu terhadap berat badan dibanding nasi pada tikus wistar. Desain penelitian ini ialah eksperimental laboratorium acak pre-post test with control group design. Subjek penelitian ialah tikus wistar jantan berusia 5-6 bulan dibagi atas 2 kelompok: kelompok nasi (kontrol) dan kelompok sagu. Sagu dimasak dalam bentuk papeda sebanyak 75 g sagu kering dan 300 mL air. Tikus diperlihara selama 2 minggu. Berat badan diukur dengan menggunakan timbangan. Data dianalisis dengan uji Wilcoxon. Hasil penelitian menunjukkan bahwa pemberian sagu sebanyak 2 cc setiap hari selama seminggu mampu meningkatkan berat badan secara bermakna (p = 0,001) sedangkan pemberian nasi menurunkan berat badan (p=0,001). Simpulan: Pemberian sagu dapat meningkatkan berat badan tikus wistar secara bermakna.Kata kunci: berat badan, sagu, nasi

Effect of herbal extract of anting-anting (Acalypha australis) on blood glucose level of Balb/C mice with induction of Streptozotocin

2011 ◽  
Vol 9 (1) ◽  
pp. 12-16
Author(s):  
RIZKY OCKTARINI ◽  
DIDING HERI PRASETYO ◽  
IPOP SJARIFAH
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
T Test ◽  
Herbal Extract ◽  
Control Group ◽  
Buffer Solution ◽  
Control Group Design ◽  
Post Test

Ocktarini R, Prasetyo DH, Sjarifah I. 2011. Effect of herbal extract of anting-anting (Acalypha australis) on blood glucose level of Balb/C mice with induction of Streptozotocin. Biofarmasi 9: 12-16. This study was conducted to determine the effect of herbal extract of anting-anting (Acalypha australis L.) on the decrease of blood glucose level of Balb/C mice induced with Streptozotocin. This research was an experimental laboratory with pre and post-test control group design, conducted in Laboratory of Biochemistry and Histology, Faculty of Medicine, Sebelas Maret University, Surakarta. The test animals used were 16 male mice, about 4-6 weeks of age with approximately 20-30 grams induced with Streptozotocin in 0.02 M citric buffer solution, and a dose of 65 mg/kg body weight. Furthermore, the mice were divided into two groups (Metformin in a dose of 1.3 mg/mice/day and herbal extract of anting-anting 1000 mg/kg BB/day) randomly, each group consisted of 8 mice. All mice were observed for GDS level after 14 days treatment period. The data obtained was processed by using the Independent-Samples T-test statistical test (unpaired t-test) with SPSS for Microsoft Windows Release 18.0. Mean of decreased GDS levels on Metformin group vs herbal extract of anting-anting (145.87 mg/dl vs 144.62 mg/dl, p=0.965). The treatment of herbal extract of anting-anting in a dose of 1000 mg/kg body weight/day could decrease blood glucose level of Balb/C mice induced with Streptozotocin that equal with Metformin.

Sign in / Sign up

Export Citation Format

Share Document