scholarly journals ADVERSE DONOR REACTION PATTERN IN A TERTIARY CARE BLOOD CENTER IN SOUTH INDIA

2020 ◽  
pp. 75-77
Author(s):  
Vinu Rajendran ◽  
Anjukrishna SA ◽  
Retheesh K H
Keyword(s):  
Blood Pressure ◽  
Reaction Rate ◽  
Tertiary Care ◽  
Primary Objective ◽  
Young Age ◽  
Predisposing Factor ◽  
Delayed Reaction ◽  
Medical College ◽  
Blood Center ◽  
First Time

Aims & Objective Primary objective is to assess the frequency and pattern of donor reaction in our blood center and secondary objective is to assess the factors associated with vaso-vagal reaction (VVR). Materials & Methods Retrospective observational study conducted by Blood Center of Sree Gokulam Medical College, Trivandrum. Details of the donors of the last 4 year (January 2015 to December 2019) including donor reaction details, age, gender, weight, donation status, type of donation and Blood Pressure(BP) were included in the study and were analyzed using IBM SPSS Version 21 Results & Discussion Out of 10,647 donors, the overall donor reaction rate is 1% while in-house and camps reaction rate were 0.96% and 3.49%. Donor reaction rate in males and females were 0.99% and 1.03%. Out of 105 reactions, 70.75 % were VVR and 19 % were Hematoma. VVR rate is 0.74. Most common VVR occurred was mild type. Young age, first time donation and voluntary donation were found to be predisposing factor for VVR. VVR rate was not associated with gender, weight and Blood Pressure (BP) of the donor. VVR in post donation phase was associated with low BP and severe VVR was not associated with low BP. Conclusion Overall reaction rate and VVR rate were 1.0% and 0.74%. Young age, first time donation and voluntary donation were found to be predisposing factor for VVR. It is important to contact donors to report any missed delayed reaction.

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

scholarly journals Uric Acid and Potassium Serum Levels Are Independent Predictors of Blood Pressure Non-Dipping in Overweight or Obese Subjects

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2970 ◽  
Author(s):  
Roberta Zupo ◽  
Fabio Castellana ◽  
Barbara Boninfante ◽  
Luisa Lampignano ◽  
Antonio Lattanzio ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Antihypertensive Drugs ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Serum Levels ◽  
Primary Objective ◽  
Ultrasound Measurement ◽  
Obese Subjects ◽  
First Time

Background: Obesity and sleeping blood pressure (BP) abnormalities are well recognized as some of the main risk factors for hypertension and cardiovascular diseases (CVDs). The primary objective of this study was to evaluate the prevalence of hypertension and non-dipping profile in overweight/obese subjects. Methods: A sample of 100 consecutive healthy overweight/obese subjects, aged 20–69 years and never treated with antihypertensive drugs was examined. Ambulatory 24 h BP monitoring was performed to diagnose hypertension and a non-dipping profile. Anthropometric, metabolic and routine hematochemical parameters were assessed. All subjects underwent ultrasound measurement of common carotid intima–media thickness. Results: Hypertension was demonstrated in 69% (n = 69) and 27% of the sample (n = 27) had a non-dipping profile. Among the hematochemical variables, estimated glomerular filtration rate (eGFR) (p = 0.02) and FT4 (p = 0.01) serum levels were higher in the hypertensive group than in the normotensive group. Lower potassium and uric acid serum levels (p = 0.05) were independent predictive factors of a non-dipping BP profile. Conclusions: This study shows, for the first time, that 1) an unexpectedly high percentage (69%) of overweight/obese subjects is affected by hypertension; 2) early hypertensive subjects have an increased eGFR and higher FT4 serum levels; 3) lower potassium and uric acid levels are independent predictors of pathological nocturnal non-dipping.

scholarly journals Clinico-Pathological Profile and Management Outcome of Fournier’s Gangrene in a Tertiary Care Hospital

2018 ◽  
Vol 9 (2) ◽  
pp. 124-130
Author(s):  
Mahmud Ekram Ullah ◽  
Amreen Faruk ◽  
Rajibul Haque Talukder ◽  
Farukuzzaman ◽  
Noor A Alam
Keyword(s):  
Tertiary Care ◽  
External Genitalia ◽  
Fournier’S Gangrene ◽  
Care Hospital ◽  
Fournier's Gangrene ◽  
Predisposing Factor ◽  
Medical College ◽  
Number Of Patients ◽  
Variable Extent ◽  
Surgery Department

Background: Fournier’s gangrene is a vascular disaster of infective origin occurring about male external genitalia. Diabetes Mellitus is an important predisposing factor. A good number of patients of this rare clinical entity are admitted frequently in our centre. Till now the disease has the potential for significant morbidity and also mortality.Objective: The study was designed to be conducted among patients suffering from Fournier’s gangrene to identify the possible source of sepsis, to denote pattern and extent of area involvement and microorganisms isolated and to observe the treatment course and outcome.Methods: This prospective observational study was carried out in BIRDEM General Hospital, Dhaka among 60 patients of Fournier’s gangrene admitted under surgery department during the period of October 2016 to January 2018 using purposive sampling method.Result: The results of this study suggest that majority of the study population were in 51 to 60 years (Mean 52±4.9) age group. All the patients were diabetic with grossly elevated blood glucose level (Mean RBS=17.3 mmol/dl). In addition to scrotum, perineum, penis, buttock and lower abdomen were also affected to variable extent (73.3%). All patients required major debridement which had to be repeated in 68.3% cases. Steptococcus pyogens was the most common organism isolated (43.3%) followed by Eschericia coli (35%) and majority were of polymicrobial type (61.6%). Mortality rate was 8.3%.Conclusion: The diagnosis and treatment of Fournier’s gangrene is enigmatic and challenging to the physician. Urgent surgical debridement along with other appropriate supportive measures can reduce morbidity and mortality.Anwer Khan Modern Medical College Journal Vol. 9, No. 2: Jul 2018, P 124-130

scholarly journals Effect of surgical menopause on serum lipid profile-a prospective study

2018 ◽  
Vol 5 (1) ◽  
pp. 27 ◽  
Author(s):  
Renymol B. ◽  
Ambili N. R. ◽  
T. D. Unnikrishnan Kartha
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Lipid Profile ◽  
Ovarian Function ◽  
Tertiary Care ◽  
Anthropometric Measurement ◽  
College Hospital ◽  
Medical College ◽  
Surgical Menopause ◽  
A Prospective Study

Background:Menopause marks the onset of cessation of ovarian function which is associated with changes in cardiovascular risk factors especially an unfavourable change in lipid profile. This is more pronounced is perimenopausal females who have undergone total hysterectomy with bilateral sapingo oopherectomy. This study aimed at looking into the changes occurring in the lipid profile and other cardiovascular risk in patients who have underwent oopherectomy over a 3 months period.Methods: The study was conducted as a case control one. We studied 70 consecutive perimenopausal patients admitted in a tertiary care teaching medical college hospital in Kerala, South India who were admitted for hysterectomy and bilateral oopherectomy over a 1year period. The lipid profile and anthropometric measurement with blood pressure recording was done prior to surgery and the same patients were followed up after 3 months when the cardiovascular risk assessment and lipid profile estimation were repeated. Here, the cases acted as controls after the end of third month.Results: It was found that after the end of 3 months of surgical menopause there was no significant change in body mass index, waist hip ratio or systolic BP. However, the DBP was higher in patients after surgery (78.68±7.94 vs 83.31±11.03, P <0.001). There was also statistically significant increase in total cholesterol (166.07±28.22 vs 242.94±45.65 [P<0.001]), TG (129.33±31.16 vs 177.06±50.57 P<0.001) and LDLc (107.83±20.06 vs 166.73±48.51 P>0.001). The HDLc was found to be 27% after 3 months of surgical menopause (59.31±8.22 vs 43.73±35 P>0.001.Conclusions: Thus, it was concluded that there was a significant unfavourable effects on lipid profile and diastolic blood pressure 3 months after surgical menopause.

Relationship between Blood Pressure and Nutrition in Adolescents

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Dr. Haresh D. Godia ◽  
Dr. Lalit H Nikam
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Female Students ◽  
Male Students ◽  
Care Hospital ◽  
Medical College ◽  
History Of ◽  
Males And Females

Aims and Objectives of study: This study was confined to healthy groups. Care was taken to exclude persons suffering from obvious disease and/ or recent history of illness Aims and Objective of present study are:- To find out BMI males and females To find out systolic and diastolic blood pressure in males and females. The various parameters which are studies are as follows:- Standing height in cms Weight in kgs. Resting pulse rate Resting systolic blood pressure in mm of Hg. Resting diastolic blood pressure in mm of Hg. Body Mass Index. Background - The study was conducted in GSMC medical college and Tertiary care Hospital. Total 100students were selected for study, out of 50 were male students and 50 were female students.

scholarly journals A study of prevalence of urogenital problem among menopausal women attending the OPD at tertiary care hospital in Bhopal

2021 ◽  
Vol 10 (3) ◽  
pp. 1062
Author(s):  
Malini Bhardwaj ◽  
Tarani Shinde
Keyword(s):  
Care Delivery ◽  
Human Life ◽  
Tertiary Care ◽  
Care Hospital ◽  
Face To Face ◽  
Medical College ◽  
Menopausal Women ◽  
First Time ◽  
Human Life Span

Background: The interest in menopausal problems has increased in recent years, due to the expansion of human life span. Women are spending more than one-third of their lives in menopausal period. Due to this fact, estrogen deprivation can cause vaginal atrophy symptoms and vasomotor symptoms, which critically diminish quality of life (QOL) in postmenopausal women.Methods: This study is a retrospective observational/analytical study conducted in the menopausal specialty clinic in J. K. Hospital, L. N. Medical College, Bhopal over a period of 1 year. All the women who attained menopause either naturally or surgically who presented first time to the clinic for any complaints were evaluated for the UG symptoms with the help of face to face interview.Results: Out of the 300 women with menopausal symptoms, 182 i.e. 60.6% were married and 52% (156) were illiterate. The most prevalent menopausal symptom in present study was vaginal dryness 240 (80%).Conclusions: There is association with lower educational levels. Hence efforts should be made educate women about the symptoms and provide care at all the levels of health care delivery. 

scholarly journals Unscarred uterine rupture: a retrospective analysis in tertiary center

2018 ◽  
Vol 7 (4) ◽  
pp. 1318
Author(s):  
Madhureema Verma ◽  
Radheshyam Bairwa
Keyword(s):  
Retrospective Analysis ◽  
Uterine Rupture ◽  
Care Center ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Predisposing Factor ◽  
Obstructed Labour ◽  
Medical College ◽  
Wide Range ◽  
Tertiary Center

Background: Uterine rupture is a catastrophic obstetrical emergency associated with a significant fetomaternal morbidity and mortality. Many risk factors for uterine rupture, as well as a wide range of clinical presentations have been identified. The objectives of the present study were to analyze the frequency, predisposing factors, maternal and fetal outcomes of unscarred uterine rupture.Methods: A retrospective analysis of cases of unscarred uterine rupture was conducted at the Department of Obstetrics and Gynaecology Jhalawar medical college Jhalawar Rajasthan from January 2009 to December 2016.Results: Our analysis comprised of 11 cases with unscarred uterine rupture. Incidence of unscarred uterine rupture is 0.01% or 1/10,000  deliveries.Conclusions: In our study there was no history of uterine scarring so the main predisposing factor are maltiparity and obstructed labour. The grand multiparas women and obstructed labour must be managed by proper trained personnel and in tertiary care center in order to avoid the morbidity and mortality.

scholarly journals Estimation of various associated factors in multiparous females undergoing primary caesarean sections at a tertiary care health centre in rural Western Maharashtra, India

2020 ◽  
Vol 8 (4) ◽  
pp. 1426
Author(s):  
Deepti Kiran Nene ◽  
Tushar Chandrakant Baheti ◽  
Vidyadhar B. Bangal
Keyword(s):  
Blood Pressure ◽  
Caesarean Section ◽  
Health Centre ◽  
Tertiary Care ◽  
Care Hospital ◽  
Neonatal Deaths ◽  
Safety Reason ◽  
Care Health ◽  
A Prospective Study ◽  
First Time

Background: Caesarean section is one of the commonly performed operation in women due to safety reason and modern techniques. Primary caesarean section in the multipara means first caesarean section done in the patients who had previously delivered vaginally once or more. Aims and objectives of this study were to know association of various parameters like Age, Parity, Haemoglobin, Blood Pressure, Baby weight, Perinatal and Maternal Mortality with primary caesarean section among multipara.Methods: This was a prospective study of primary caesarean section in multipara women admitted at tertiary care hospital in western rural Maharashtra during the period of 6 months from January 2018 to June 2018. Multipara with pregnancy of >28 weeks gestation (gravida 2 and above), each of whom has had a previous vaginal delivery of >20 weeks gestation were included. Women with previous abortions and previous section were excluded.Results: Total 1705 sections were performed during the same period out of total 4648 deliveries. Out of these sections 194 sections were performed in multipara for the first time. Maximum numbers of patients (58%) were in the age group of 15-24 years and Parity 2 (68%). Almost 70% women among multipara have Hb <11 Mgm/dl. Most of the patients (84.53%) have normal Blood pressure readings. Most of the babies’ i.e.70 (36.08%) have birth weight in the range of 2.5-3 kg. Out of 194 deliveries, there were only 3 neonatal deaths (1.54%) and 1 maternal death (0.51%).Conclusions: Proper antenatal and intrapartum care and early referral can reduce the maternal and perinatal morbidity and mortality in multipara. 

scholarly journals A Comparative study to observe the effect of Meditation in Hypertension

2018 ◽  
Vol 1 (01) ◽  
Author(s):  
Rajesh Kolarkar ◽  
Rajashree Kolarkar
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Primary Objective ◽  
Study Group ◽  
Sitting Position ◽  
Interventional Study ◽  
Male And Female ◽  
Medical College ◽  
Group A ◽  
Secondary Objective

Primary objective was to evaluate and compare the change or reduction in systolic and diastolic blood pressure (BP) in sitting position from baseline (week 0) to the end point (Week 12) between two groups, to evaluate and compare the change or reduction in Stress value between two groups and Secondary Objective was to observe and compare change in lipid profiles between two groups. Methods: In a comparative interventional study Group A 30 patients of hypertension of male and female were given training in relaxation and meditation. Study was performed in YMT Ayurvedic Medical College and Smt. K.G. Mittal college and Sanjivani Ayurvedic centre Mumbai.The study was conducted on 30 patients including both male and female practicing daily meditation for 12 weeks to observe effect of meditation in hypertension. This showed an overall reduction of systolic and diastolic blood pressure.

scholarly journals A prospective observational study for the evaluation of maternal and fetal outcome in patient with eclampsia

2017 ◽  
Vol 5 (5) ◽  
pp. 1785 ◽  
Author(s):  
Santosh Kumar Dora ◽  
Lalmohan Nayak ◽  
Benudhar Pande ◽  
Atal Bihari Dandapat
Keyword(s):  
Blood Pressure ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Care Facility ◽  
Health Care Facility ◽  
Fetal Outcome ◽  
Maternal Complications ◽  
Medical College ◽  
Labour Room

Background: Eclampsia continues to be a measure health issue in developing country. In order to get a comprehensive data on eclamptic patients we conduct a prospective observational study to address the maternal and fetal complication during pregnancy.Methods: It is a prospective observational study conducted in a tertiary care medical college between the periods September 2016 to February 2017. During the period all patients with eclampsia admitted to the labour room were taken. Any patients with known epilepsy were excluded from the study.Results: During the period 3780 women were admitted to the labour room, out of which 56 women had eclampsia with an incidence of 1.48%. Out this antenatal eclampsia was most common with an incidence of 91.08% followed by intra partum 4 (7.14%) and postpartum eclampsia 1 (1.78%). Majority of patients 54 (96.43%) were unbooked or inadequately supervised. Most of the patient had normalization of blood pressure after oral nifedipine 46 (82.14%), only 10 (17.86%) patient required additional injection labetalol for control of blood pressure. The maternal complications were placental abruption 8 (14.28%), HELLP 6 (10.71%), pulmonary edema 1 (1.78%), acute renal failure 1 (1.78%), DIC 1 (1.78%) and maternal death 2 (3.57%). Out of fifty six babies delivered 42 (75%) had live birth and 14 (25%) had still birth. A total of 17 (40.42%) had IUGR, 17 (40.47%) require SNCU admission post-delivery.Conclusions:Eclampsia still remains the major cause of maternal and fetal morbidity. In low resource countries improvement in health care facility, adequate antenatal supervision, and timely referral will reduce the maternal and fetal complication. 

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