scholarly journals Prevalence and Determinant of Depression among Multi-Drug Resistance Tuberculosis: Study in Dr. Kariadi General Hospital

2020 ◽  
Vol 40 (2) ◽  
pp. 88-96
Author(s):  
Mahalul Azam ◽  
Arulita Ika Fibriana ◽  
Fitri Indrawati ◽  
Indah Septiani

Backgrouds: Multi-drug resistance tuberculosis (MDR-TB) adds the burden of tuberculosis (TB). Depression is a common comorbidity in TB patients. Prevalence of depression among MDR-TB patients was higher, i.e. 11-70%. Prevalence of depression among TB patients in Dr. Kariadi General Hospital was 51.9%. Previous study reported the determinants related to the depression in MDR-TB patients. This study explored the prevalence of depression in MDR-TB patients and its determinants. Methods: This study was a cross-sectional study conducted from July-August 2019. Data consisted of primary and secondary data from Dr. Kariadi General Hospital patients. Sample in this study involved 72 respondents, over 16 years old from 151 registered MDR-TB patients. Depression status was determined using Depression Anxiety Stress Scales obtained from the medical record. Subjects’ characteristics and determinants were collected from primary as well as secondary data. Descriptive data were presented in proportion. Chi-square test continued by Binary logistic regression was performed to determine the association between depression status and its determinants. A P-value

Author(s):  
I. Gusti Ayu Putu Putri Ulandari ◽  
Putu Dyah Widyaningsih

Background: Coronavirus disease-2019 (COVID-19) is a novel coronavirus type infection disease that was first reported at Wuhan city, Hubei province, China in December 2019. Cases of COVID-19 in Indonesia were increasing, reaching up to 287,008 confirmed cases on 30th September 2020. Sanjiwani general hospital Gianyar, Bali, one of the COVID-19 referral hospital at Gianyar, Bali, has treated as many as 149 confirmed COVID-19 cases from August to October 2020. The most significant laboratory parameter associated with COVID-19 severity was C-reactive protein (CRP) and neutrophil to lymphocyte ratio (NLR).Methods: This study is a descriptive cross-sectional study. Data were gathered through secondary data from the medical records using the total sampling method. Descriptive analyses were performed to describe the samples characteristics and to calculate the mean CRP level. Meanwhile, the chi-square test was done to investigate the association between CRP level and the severity level of COVID-19. The result is considered statistically significant if the p value is <0.05Results: Most of the samples are >60 years old (24.4%), female (56.6%), and have diabetes mellitus as their comorbid (46,7%). The mean CRP level is 8.9 mg/L. CRP level >8.9 mg/l significantly affects COVID-19 patients’ severity with the p value of 0.000 (p<0.005). The higher the initial CRP level of COVID-19 patients, the higher the severity level will be.Conclusions: There is an association between the increased CRP level at the beginning of hospital admission and the severity of COVID-19 patients.


2017 ◽  
Vol 33 (7) ◽  
pp. 325
Author(s):  
Erma Nurjanah Widiastuti ◽  
Yanri Wijayanti Subronto ◽  
Dibyo Promono

PurposeThe purpose of this study was to identify the determinants of multidrug resistant events in patients with tuberculosis in Dr. Sardjito Hospital in Yogyakarta.MethodsA cross-sectional study was conducted involving 122 patients with suspected MDR TB consisting of 61 cases of MDR TB and 61 non MDR TB cases. The data collected were secondary data from MDR TB.06 registers, medical records, MDR TB.03 registers, and MDR TB patients' baseline data forms at Dr. Sardjito Hospital Yogyakarta from January 2012 until September 2016. Data were analyzed to determine the correlation between independent variables and dependent variable using Chi-Square tests, and to know the most dominant risk factors using multiple logistic regression tests.Results MDR TB patients’ characteristics showed there were more males (63.93%), age >45 years (52.46%), previously TB treatment (96.72%), never smoking (75.41%), no contacts with MDR TB patients (86.89%), and never examined for HIV-AIDS (59.02%). The analysis showed there was no significant association between age, sex, previous TB treatment, smoking, contact with MDR TB patients, and HIV-AIDS status with MDR TB incidence in Dr. Sardjito Hospital Yogyakarta (p value >0.05).Conclusion The variables of age, sex, previous TB treatment, smoking, contacts with MDR TB patients, and HIV-AIDS status were not risk factors for MDR TB incidence in Dr. Sardjito Hospital in Yogyakarta.


2021 ◽  
Author(s):  
(MD

Abstract Background: Undiagnosed depression among university students has an adverse effect on the wellbeing and academic performance of students. This study aimed to assess the prevalence of depression and associated factors among Debre Birhan university students. Methodology: Institutional based cross-sectional study design is conducted in Debre Birhan University from April to June 2013 E.C. Three hundred sixty nine students participated in this study which was selected by simple random sampling technique. Data were collected by using a self-administered PHQ-9 standard depression questionnaire. First the data was entered into in Epidata 3.1 and then was exported to SPSS version 20 for analysis. Associated factors were identified using binary logistic regression and variables with a p-value < 0.05 were declared as statistically significant factors with the outcome variables. Result: All of the study subjects were between ages 18 and 33 with a mean age of 22.65 9 ± 2.78. The overall prevalence of depression is 17.1%. Among this according to PHQ-9 scores cut scores, 161(43.6 %) scored as normal (0–4), 145(39.3%) scored as mild (5–9), 53(14.4%) scored as moderate (10–14), 4(1.1%) scored as moderately severe (15–19) and 6(1.6%) students scored as sever (> 20). In multivariate analysis being female AOR = 9.28[3.47–24.81], academic year AOR = 0.236[0.059–0.936], smoking 26.3[9.33–74.1] and alcohol use AOR of 2.62[0.95–7.21] are significantly associated with depression. Conclusion and recommendation: This study found a considerable proportion of undergraduate students with depression. Higher institutions need to pay special attention to students especially those who are female, junior students, smokers and alcohol users.


2020 ◽  
Vol 29 (2) ◽  
pp. 198-203
Author(s):  
Ibnu Mas'ud ◽  
Ujainah Zaini Nasir ◽  
Ceva Wicaksono Pitoyo ◽  
Ikhwan Rinaldi

BACKGROUND Based on the regulation of the Indonesian Ministry of Health No. 15 of 2016 about health istithaah for the Hajj, patients with tuberculosis (TB) can be categorized into ineligible or temporarily ineligible pilgrims. This study aimed to know the characteristics of pilgrims with TB and determined their level of fitness for fulfilling the health istithaah. METHODS A cross-sectional study of pilgrims from Jakarta who were receiving TB treatment during the Hajj in 2018 was conducted with consecutive sampling. The secondary data was collected from the Hajj Integrated Computer Health System 2018, TB registered form, and six-minute walk test (the fitness level data) conducted by the District Hajj Health Team at district health centers in DKI Jakarta and Pondok Gede before the Hajj embarkation in June–July 2018. The questionnaire to the Indonesian Hajj Health Team during pilgrimage was also included as additional data. RESULTS Thirty-one pilgrims received TB treatment and completed the intensive phase of TB treatment, but 29 pilgrims had no symptoms. Among them, 2 patients had MDR-TB. Most of them were male aged ≥40 years old. Twelve pilgrims with TB have a sufficient fitness. All pilgrims were able to run the pillars of the Hajj. CONCLUSIONS Pilgrims with TB, including MDR-TB, who had completed the intensive phase with a negative sputum smear test were declared eligible for the Hajj with assistance.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Tichaona Sagonda ◽  
Lucy Mupfumi ◽  
Rumbidzai Manzou ◽  
Beauty Makamure ◽  
Mqondisi Tshabalala ◽  
...  

We conducted a cross-sectional study of second line drug resistance patterns and genetic diversity of MDR-TB isolates archived at the BRTI-TB Laboratory, Harare, between January 2007 and December 2011. DSTs were performed for second line antituberculosis drugs. XDR-TB strains were defined as MDR-TB strains with resistance to either kanamycin and ofloxacin or capreomycin and ofloxacin. Strain types were identified by spoligotyping. No resistance to any second line drugs was shown in 73% of the isolates, with 23% resistant to one or two drugs but not meeting the definition of XDR-TB. A total of 26 shared types were identified, and 18 (69%) matched preexisting shared types in the current published spoligotype databases. Of the 11 out of 18 clustered SITs, 4 predominant (>6 isolates per shared type) were identified. The most and least abundant types were SIT 1468 (LAM 11-ZWE) with 12 (18%) isolates and SIT 53 (T1) with 6 (9%) isolates, respectively. XDR-TB strains are rare in Zimbabwe, but the high proportion of “pre-XDR-TB” strains and treatment failure cases is of concern. The genetic diversity of the MDR-TB strains showed no significant association between SITs and drug resistance.


BioMedica ◽  
2020 ◽  
Vol 36 (4) ◽  
pp. 374-378
Author(s):  
Muntazir Mehdi ◽  
Muhammad Waseem ◽  
Dr. Hafiza Swaiba Afzal ◽  
Ahmad Zeeshan Jamil ◽  
Muhammad Junaid Iqbal ◽  
...  

Background and Objective: Interstitial lung disease (ILD) causes depression due to its painful course in patients. The aim of this study was to determine the prevalence of depression and find the association of depression with selected clinical variables in patients with ILD. Methods: This questionnaire based cross-sectional study was done at the department of pulmonology, District head quarter hospital Sahiwal from 1st Oct 2019 to 31st March 2020. The questionnaire was distributed among the diagnosed cases of ILD who presented in outpatient department of DHQ Sahiwal after taking informed consent. The depression scoring was done in them according to Beck depression inventory II. Frequency distribution statistics and inferential statistics were done by using Statistical Package for Social Sciences (SPSS) version 20. P-value < 0.05 was taken as statistically significant. Results: Depression was graded into four types according to Beck depression inventory II scoring system. Depression levels of minimal, mild, severe and extremely severe were found to have frequencies of 42.90, 14.30, 31.40 and 11.4% respectively. Depression was more prevalent in females (77.14%). Sixty two percent of severely depressed had rural background. Three fourth (75%) of severely depressed patients were from lower class group. Half of the severely depressed patients were suffering from hypertension. One fourth had ischemic heart disease. Illiteracy dominated in severely depressed where 3/4th of the participants had not received any education. Our study found statistically significant result of Beck score with socioeconomic groups (P = 0.037). High statistically significant result was also found when Beck scoring was associated with co-morbidities (P = 0.001). Conclusions: The increased frequency of depression in the patients of ILD was associated with many demographic factors. The development of improved methods for the assessment of ILD and its co-morbidities could have profound effects on the quality of life and expected survival of ILD patients.


2021 ◽  
Vol 1 (2) ◽  
pp. 58
Author(s):  
Vita Murniati Tarawan Lubis ◽  
Rizky Aji Pambudi ◽  
Vitriana Biben

Judo is described as a physical contact sport. A judo athlete should try to make themovement of throwing, slamming and holding the opponent's strength during the game. To perform the technique well, muscle strength is important in judo athletes. As one of the components of physical fitness in athletes, muscle strength has an important role for the judo athlete to maximize their performance and have their best achievement. Therefore, this study aims to determine the relationship of muscle strength level of judo athletes with their achievement in Pekan Olahraga Nasional (PON) XVIII 2012 in Riau. A cross-sectional study using the analytical method was done on 19 Judo athletes as subjects. Data are collected from secondary data as a result of muscle strength examination measured by push, pull, and leg dynamometer, conducted by Komite Olah Raga Nasional (KONI) West Java. Judo athletes who participated Pekan Olah Raga Nasional (PON) XVIII 2012 championship in Riau were included while athletes who injured were excluded. In this study judo athletes who won medals (got achievement) were 7 athletes, while those who did not win medals (did not get the achievement) were 12 athletes. The significance value (p-value) for the relationship of muscle strength with judo athlete’s achievement as measured by push dynamometer was 0.764, pull dynamometer was 0.570, and leg dynamometer was 0.132. In conclusion, there isno significant relationship between the level of muscle strength with the judo athlete’s achievement on Pekan Olah Raga Nasional (PON) XVIII 2012.


2019 ◽  
Author(s):  
Enguday Tirfeneh ◽  
Mengesha Srah

Abstract Background depression is one of the most serious and prevalent mental illnesses that can result in serious disability and ending life by committing suicide and homicide. The risks of having depression are substantially higher in persons who have parental neglect when compared to the general population.Objective To detect prevalence of depression and its association with parental neglect among adolescents in governmental high schools at Aksum town, Tigray, Ethiopia 2019Method A facility based cross-sectional study was conducted from January 1-30/2019 at Aksum town high schools. Public health questionnaire was used in this study to detect Depression. Study participants were selected using simple random sampling technique. Data was collected with face to face interview. Data was analyzed using statistical package for social science version 22. Bivariate and multivariate logistic regressions were used to see the association between depression and parental neglect. Adjusted Odds ratio at a p-value <0.05 with 95% confidence interval was taken to declare statistical significance of variables.


Author(s):  
Jayashree Kannappan ◽  
Abhilash Kannappan ◽  
V. S. Prema Subathiraa ◽  
Shanthi Dinakaran ◽  
P. S. Jikki Kalaselvi

Background: Women are twice as likely as males to suffer from mood disorders, which tend to cluster around the childbearing years. Depression negatively influences maternal and neonatal outcomes. Objective: The objective of the study is to estimate the prevalence of depression in pregnant women aged 18 – 35 yrs and to identify predictors accounting for variability across estimates during pandemic. Methodology: This is a cross sectional study, conducted among 74 pregnant women coming for antenatal checkups in the Sriperumbudur, Chennai. Using height and weight values obtained from the sample, Body Mass Index (weight in kg/height in metre squares) was calculated. Hamilton – Depression Scale (HAM-d) was applied after initial psychiatry work up to all women who were selected for the interview. Mean of parameters were assessed and correlation value were calculated by Fisher’s exact test. The statistically significant P value was less than 0.05. Results: The sociodemographic variables have been found as significant contributors in explaining the variability of the prevalence rates of antenatal depression. It showed positive correlation between economic status and depression (p<0.05) and a negative correlation between obesity and depression (p>0.05). According to the findings, fewer than 1/3rd of pregnant women experience depression as a result of life circumstances such as economic crises in order to support their families. These were identified as significant associate variables (P>0.05). And also, this study identified insufficient socioeconomic assistance were more likely to experience multiple psychological discomfort [atleast 1] than women who got appropriate economic support. (r = -0.118, P < 0.001) Conclusion: In rural Tamilnadu, the prevalence of antenatal depression among women is significant. Antenatal Depression is caused by a number of circumstances, including physical, obstetric, economic, and family-related issues. To treat these antenatal depression risk factors, comprehensive therapies are required.


2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Fauzan Abdurrahman ◽  
Sri Suryanti ◽  
Aaron T Sihombing

The risk of high grade PCa in Asia in relation to BMI had positive or negative effect. The objective of this study is to know the relationship between BMI and Gleason score in Indonesian PCa patients. A cross sectional study was conducted in Hasan Sadikin General Hospital. The data were secondary data taken from medical records of prostate adenocarcinoma patients in Hasan Sadikin General Hospital. Ordinal data were analyzed using Chi square and correlation using Spearman. All calculation was done using SPSS 24. There were 95 Indonesian PCa patients. 78 patients is in normal BMI range. Of those 41 patients (52.6%) is in high level of Gleason score. 17 patients is in high BMI range. High Gleason score was found in 11 patients (P = 0.362; rs = 0.094). Conclusion, there is no relation between BMI in Indonesian PCa and Gleason score.   Keywords : Prostate adenocarcinoma (PCa); BMI; Gleason score.


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