MORPHOFUNCINAL CHARACTERISTIC OF THYMUS IN SEVEN MONTHLY RATS UNDER CONDITIONS OF MOUNTAIN HYPOXIA OF KYRGYZSTAN
In recent years, the problem of hypoxia has attracted increasing attention of experimenters and clinicians, since studying various aspects of hypoxia has shown the universal role of short-term or longer-term oxygen deficiency in the regulation of body activity and the development of pathology. The most populated are the regions located in the low mountains (from 200 to 1400 m above sea level) and the middle mountains (from 1400 to 2500 m). The highlands fall on a height of up to 3200 m. Above is a non-residential snow highlands and above the highlands. A study of the histology of thymus was carried out in 62 seven-month-old rats living in various environmental and climatic conditions in Kyrgyzstan. Morphofunctional structures of the thymus gland in seven monthly rats were studied. Study methods: 1. Anatomical methods (preparation). 2. Histological methods (hemotoxylin-eosin coloring, according to Van Gizon). As a result of a study of seven monthly rats in Bishkek (770 m above sea level) under low-altitude conditions, all control group values are within normal limits. Indicators in Tuya-Ashu in the highlands (3200 m above sea level), a noticeable change in cells, for example, the number of lymphoblast indicators has increased. In the conditions of the middle mountain Cholpon-Ata (1660 m above sea level), cell performance decreased. The results of this study of seven monthly rats in the conditions of the highlands of Naryn (2000 m above sea level), the dynamics of cell populations in the unit of the conditional area of the cortical substance of the timus slice in tseven monthly rats showed a slight decrease in cell performance compared to the average Cholpon-Ata. Thus, Bishkek in low-altitude conditions, i.e. 770 m above sea level, all indicators of the control group are within the norm. In the highlands (3200 m above sea level), a noticeable change in cells, for example, the number of lymphoblasts increased by 3.44%, average lymphacites increased by 2.03%, small lymphacites by 316.8%. Apoptotic bodies 59.8%, mitoses by 2.1%, Taurus Gassal increased by 0.09%. Macrophage index increased by 0.12%. Stereometric characteristic of crustal thymus substance of seven monthly rats 26 .67%. The cerebral matter increased by 6.99%., The intra-pulmonary perivascular space (runway) by 1.66%. Interdigital septs increased by 7.98%. Keywords: Timus. seven-month-old rats. Lowland, Midland and Highlands