scholarly journals Cigarette Smoking and Hyperglycaemia in Diabetic Patients

2018 ◽  
Vol 6 (4) ◽  
pp. 634-637 ◽  
Author(s):  
Mutiara Indah Sari ◽  
Nisrina Sari ◽  
Dewi Masyithah Darlan ◽  
Raka Jati Prasetya
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Level ◽  
Hba1c Level ◽  
Fasting Blood Glucose ◽  
Postprandial Glucose ◽  
Diabetic Patients ◽  
Significant Difference ◽  
Study Population ◽  
Postprandial Glucose Level

BACKGROUND: The incidence rate of diabetes mellitus has increased throughout the year. Various studies indicate that smoking may affect glucose metabolism and cause hyperglycemia in diabetes mellitus. This study aimed to compare the blood glucose and HbA1c level in diabetic smoking patients and non-smoking diabetic patients.METHODS: This study used the cross-sectional approach. The study population consisted of 30 diabetic smoking patients and 30 non-smoking diabetic patients. The diabetes history and the smoking status of the study population obtained by questionnaire-based interview, the blood glucose and HbA1c level were measured by hexokinase and immunoturbidimetry method using cobas 6000 analyser module c501  (Roche Diagnostics, Switzerland).RESULTS: The result in this study showed the fasting blood glucose, postprandial blood glucose, and HbA1c were higher by 23.64 mg/dl (p = 0.325), 58.00 mg/dl (p = 0.016), 0.39% (p = 0.412) in smoking diabetic patients compared to non-smoking diabetic patients. After statistical analysis, there was a significant difference (p < 0.05) of postprandial glucose level between smokers group and non-smokers group, but the non-significant difference of fasting blood glucose and HbA1cCONCLUSIONS: This study concluded that there was a significant difference in postprandial glucose level between smokers group and non-smokers group but the non-significant difference of fasting blood glucose and HbA1c.

scholarly journals Assessment of the salivary glucose as a non-invasive test for diabetic patients

2019 ◽  
Vol 6 (6) ◽  
pp. 2289
Author(s):  
Kajol Thapa ◽  
Saroj Kunwar ◽  
Sonu Thapa ◽  
Asmita Phuyal ◽  
Sahil Rupakheti
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Glucose Levels ◽  
Non Invasive ◽  
Invasive Test ◽  
Blood Glucose Levels ◽  
Institutional Review

Background: Over the recent year there has been a startling rise in the number of people suffering from diabetes mellitus. Estimation of blood glucose levels has been an essential laboratory investigation for screening and monitoring of diabetes. Saliva is one of the secretions in human body whose collection is easy and non-invasive. Salivary glucose hence could serve as an easy and non-invasive tool.Methods: Institutional review committee of NHRC gave us permission to carry out this study. 105 subjects with Type 2 diabetes mellitus who attended the OPD at Star hospital, Sanepa, Lalitpur, Nepal and 106 healthy individuals were consented to participate in this study. Glucose was measured by the GOD-POD (Glucose oxidase peroxidase) methods using the semi-autoanalyser and salivary glucose was compared with corresponding blood glucose levels.Results: A significant positive correlation of fasting salivary glucose level and fasting blood glucose level was observed in healthy (r=0.241, p=0.001) and in diabetic patients (r=0.202, p=0.001).Conclusions: The study implies a potential for saliva in monitoring and screening of diabetes mellitus.

scholarly journals A Comparison Between the Effect of Three Types of Low-Calorie Diets on Controlling Blood Glucose and Lipids in People with Type 2 Diabetes

2018 ◽  
Vol 8 (1) ◽  
pp. 18
Author(s):  
Zoleika Moazezi ◽  
Seyed Reza Hosseini ◽  
Parvin Sajadi Kaboudi ◽  
Bahareh Esbakian ◽  
Sahar Rahmani ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Serum Lipids ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Low Calorie ◽  
Significant Difference

The blood glucose level of people with diabetes can be normalized through an appropriate diet, physical activity, the use of chemical drugs and medicinal plants. This study aims to investigate the effects of low-calorie diets (1200, 1500, and 1800 kcal) on glucose and serum lipids in poorly controlled type 2 diabetic patients. This clinical trial was conducted among 60 patients with type 2 diabetes mellitus. The criteria for entering the study were fasting blood glucose higher than 130 mg/dl, hemoglobin A1C higher than 7% and BMI higher than 25. Blood glucose, fasting blood glucose and lipid levels were measured before and after intervention two hours after each meal. Patients were trained by an expert. Then, the questionnaires were completed and analyzed. In this study, the mean fasting blood glucose level in patients who used 1500 and 1200 kcal diet decreased significantly after intervention (p&lt;0.05). Glucose decreased significantly after two hours using a 1500  kcal diet (p&lt;0.009). In addition, triglyceride and cholesterol levels were significantly reduced in patients who used the 1500 kcal diet (p&lt;0.05). Although, there was no significant difference in blood glucose levels between 1200, 1500 and 1800 kcal diets based on gender, residencency and BMI. Regarding the fact that there was no significant difference in reducing blood glucose and serum lipids between 1200 and 1500 kcal diets. It is recommended to use a 1500 kcal diet instead of 1200 kcal diet, which imposes fewer limitations and is easier to tolerate.

scholarly journals Effect of Local Anesthesia with 1:100,000 Epinephrine on Glycemic Level of Type II Diabetic Patients Undergoing Oral Surgery

1969 ◽  
Vol 11 (4) ◽  
pp. 181-184
Author(s):  
Muhammad Tariq Khan ◽  
Muhammad Ilyas ◽  
Salman Khan ◽  
Jawad Ahmad Kundi ◽  
Fariha Kifayat
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Local Anesthesia ◽  
Glucose Level ◽  
Oral Surgery ◽  
Diabetic Patients ◽  
Type Ii ◽  
Glycemic Level ◽  
Significant Difference

Background: The rate of type II diabetic patients is increasing and results in oral manifestations. The oral surgery needsextraordinary measures in these patients.Objective: To assess the effect of anesthetic agent with 1:100,000 epinephrine and without epinephrine in the blood glucose levelof diabetic patients.Material and Methods: This was a randomized study of 60 patients having type 2 diabetes mellitus who were undergoing toothextraction. The study was double blind. 30-70years aged patients were selected. Blood glucose level was monitored 15 minutesbefore giving local anesthesia and after 20 minutes of the injection. ANOVA was used for comparison between groups.Results: No significant difference was seen in glycemic level using local anesthesia with 1:100,000 epinephrine (p=0.345). Therewas slight decrease noted in the blood glucose level of both groups.Conclusion: The use of 2% local anesthesia with 1:100,000epinephrine didn't cause hyperglycemia in diabetic patients.Keywords: Diabetes Mellitus, Local Anesthesia, Epinephrine, Tooth Extraction, Lidocaine.

scholarly journals Pattern of Dysglycaemia and Family Risk Factors for Diabetes Mellitus among Patients Attending General Outpatient Clinic of Federal Teaching Hospital Ido-Ekiti, Ekiti State, Nigeria

2020 ◽  
Vol 2 (6) ◽  
Author(s):  
Gbadebo Oladimeji Ajani ◽  
Olusegun E. Gabriel-Alayode ◽  
Segun Alex Atolani ◽  
Michael Osisiogu Soje ◽  
Michael Adeyemi Olamoyegun ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Glucose ◽  
Communicable Disease ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Family Risk Factors ◽  
Family Risk ◽  
Family History Of Diabetes ◽  
Study Population

Diabetes mellitus is a non-communicable disease that currently affects over 366 million people worldwide and its prevalence is likely to double by 2030. Therefore, the need to screen for diabetes mellitus has become an impetus. The objective of the study was to determine the prevalence of dysglycaemia and significance of familiar risk factors for diabetes mellitus among the study population. One hundred and thirty-two and 48 consecutive non-previously diagnosed DM and previously diagnosed DM patients respectively were recruited from the same clinic. An interviewer administered questionnaire was applied and blood samples were taken for blood glucose. The prevalence of dysglycaemia was 36.2% and only 40.6% of the diabetic patients who did fasting blood glucose had glycaemic control. Family history of Diabetes mellitus in the first generation was significantly associated with chance of developing diabetic mellitus in the study population. In conclusion, it is important physicians begin to be very proactive in the screening for blood glucose in order to detect them early and forestall complications that are associated with late diagnosis of diabetes mellitus.

scholarly journals Alterations of liver enzymes in T2DM: a case control study

2018 ◽  
Vol 5 (6) ◽  
pp. 1521
Author(s):  
Chandrashekhar G. S.
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Case Control Study ◽  
Liver Enzymes ◽  
Fasting Blood Glucose ◽  
Case Control ◽  
Diabetic Patients ◽  
Histopathological Analysis ◽  
Control Study

Background: Liver plays an important role in regulation of blood glucose in fed state as well as in fasting. Diabetes mellitus can result as a consequence of liver disorder and vice versa. Objective of the present study is to compare the liver enzymes in type 2 diabetic patients as compared to non-diabetic patients.Methods: A case- control study was conducted in Clinical Biochemistry Laboratory, Adarsha Super speciality Hospital, Udupi from April 2018 to August 2018. The data of 174 diabetic patients and 118 healthy people as controls was collected. Fasting blood glucose, aspartate aminotransferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) were estimated in the study subjects.Results: It was found that AST levels (47.55±4.69U/L) in diabetics extremely significantly high as compared to controls (33.51±2.33U/L). ALT levels were insignificantly high in diabetics compared to controls. ALP was significantly elevated (p=0.0002) in diabetics. Correlation study showed a weak positive correlation between AST, ALT and blood glucose. Odds ratio showed a higher risk of liver enzyme elevation in diabetics. Risk of elevation of AST was found to be 1.65 times high and ALT was 1.25 times high in diabetics compared to non-diabetics.Conclusions: Diabetics had high liver enzymes as compared to non-diabetics. An association was found between type 2 diabetes mellitus and liver enzymes. For better characterization of cause and effect, further studies need to be done on alterations in liver function tests along with the histopathological analysis of liver biopsy samples.

scholarly journals Penggunaan Insulin Basal dalam Praktek Sehari-hari: Panduan Praktis untuk Dokter Umum

2017 ◽  
Vol 8 (2) ◽  
pp. 53
Author(s):  
Dani Rosdiana
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Basal Insulin ◽  
Hba1c Level ◽  
Blood Sugar Level ◽  
Fasting Blood Glucose ◽  
Effective Agent ◽  
Best Parameter ◽  
Prevalence Of Diabetes Mellitus

Prevalence of diabetes mellitus in Riau have reached 10,4 %, it’s higher than national pravelence. Hence, it’s needmore attention from physician. The important thing in managing DM is how to restrain controlled blood sugar level.The best parameter to evaluate controlled blood sugar level is level of HbA1c. Fasting blood glucose is one ofimportant component which determine HbA1c especially HbA1c more than 8,5%. There are some pharmacologyagent to decrease HbA1c level, and insulin is the most effective agent. Why physician needs insulin?It was caused by impairment of betha cell pancreas was directly propotional with DM progressiveness. Comprehensionand capability for using basal insulin are important to physician, not only for internist but also for general practinioner.As we know that general practinioner have a competency to manage DM without complication. Guidance for usingsimple and practical basal insulin is expected will facilitate physician to manage blood sugar level of DM patient.

scholarly journals Influence of Patient Characteristics on The Type of Insulin Therapy Obtained by Diabetes Type 2 Outpatient in Denpasar Municipality

2017 ◽  
Vol 1 (2) ◽  
pp. 139
Author(s):  
Luh Putu Febrayana Larasanty ◽  
I GNA. Dewantara Putra ◽  
Rhyce Dewata Sari ◽  
Komang Dede Saputra ◽  
I GA. Gede Minanjaya ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Insulin Therapy ◽  
Glucose Level ◽  
Medical Records ◽  
Fasting Blood Glucose ◽  
Patient Characteristics ◽  
Postprandial Blood Glucose

This study aims to investigate the influence of patient characteristics on the choice of insulin therapy in type 2 diabetes mellitus outpatients in Denpasar municipality. This is a descriptive analysis study using the patient's medical records as research material. Patients who meet inclusion and exclusion criteria are being recorded based on their medical records. Characteristics that are taken are age, gender, fasting blood glucose level (FBG), 2-hour postprandial blood glucose level (2-hours PPG) and HbA1c values of patients. Types of insulin therapy gained from patient medical records and drug use report in pharmacy. Characteristics data and type of insulin analyzed using correlation test to determine the effect of the patient characteristics on the selection of insulin therapy. 43 patients became the research subject. Males gendered patients (72.09%) and the patients aged less than 65 years (90.70%) are the dominant characteristics of the research subjects. The average value of FBG of patients is 212 mg / dL; 2-hours PPG 280 mg / dL and HbA1c 10.1%. There is a correlation between sex, age, HbA1c value and FBG with the type of insulin obtained by patients (p <0.05). Based on the results of statistical tests, age and gender have a strong correlation on insulin choice, HbA1c and FBG level has a moderate influence and 2-hours PPG have a weak correlation. Patient characteristics had an influence on the type of insulin choice for diabetes mellitus type 2 outpatient in the Denpasar municipality.

scholarly journals EFFECT OF AEROBIC EXERCISES AND RESISTANCE TRAINING ON GLUCOSE LEVELS IN TYPE 2 DIABETIC SUBJECTS.

2017 ◽  
Vol 10 (7) ◽  
pp. 360
Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Resistance Training ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.

The Effect of Biochanin A as PPAR γ agonist on LDL Particles Diameter and Type 2 Diabetic Dyslipidemia

2019 ◽  
Author(s):  
Darya Ghadimi ◽  
Mohammad Taghi Taghi Goodarzi ◽  
Mahdi Bahmani ◽  
Zohre Khajehahmadi
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Male Rats ◽  
Biochanin A ◽  
Diabetic Patients ◽  
Low Density ◽  
Diabetic Dyslipidemia ◽  
Ldl Particles

Background and Aims: Small dense  low-density lipoproteins (sd-LDL) particles are smaller and heavier than typical LDL ones. They can penetrate into the endothelium of coronary arteries more easily because of their small size. Diabetes mellitus is accompanied by dyslipidemia such as increasing concentration of plasma very low density lipoprotein and sd-LDL. Peroxisome proliferator activated receptor γ (PPARγ ) can decrease the level of sd-LDL in plasma. Biochanin A (BCA), a natural compound, is a PPARγ agonist. The present study was designed to investigate the effect of BCA on sd-LDL-Clolesterol level in diabetic animals. Materials and Methods: Adult male rats (Wistar strain) were used as the animal models in this study. Animals were made diabetic by single intraperitoneal injection of Streptozotocin- Nicotinamide and then treated by 1 and 5 mg/kg of BCA for 28 days. Body weight and fasting blood glucose were also tested before and at the end of treatment. Furthermore, the size of LDL particles were measured by nondenaturing polyacrylamide gradient gel electrophoresis assay. Results: Results of the present study indicated that BCA administration at dose of 5mg/kg decreased fasting blood glucose level and increased body weight and diameter of LDL particles in diabetic animals significantly. Conclusions: BCA seems to be an appropriate agent in diabetes mellitus, because it improves the diabetic dyslipidemia, which is the most important complication in diabetic patients.

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