Manufacturing Technique and Antimicrobial Activity of Silver Nanoparticles
Recently, the biomaterial is in rapid development stage, which could be widely applying in medical application, due to its biodegradability, nontoxic and biocompatibility. Chitosan is naturally abundant polymers have the biodegradability, nontoxic and biocompatibility. In this research, the chitosan and silver nitrate were used to develop the antibacterial agent via nanotechnique. In the reaction system, the reaction time and stirring speed were discussed, which will affect the surface plasmon resonance. The particle sizes were measured using transmission electron microscopy (TEM) and UV visible spectrophotometry. The silver nanoparticles size was below 100 nm via TEM. In addition, the results of antimicrobial activity indicated that the antibacterial agent has well antimicrobial activity on staphylococcus aureus. Due to the silver nanoparticle provides relatively higher surface area to contact with bacteria affect DNA molecules by losing their replication abilities.