scholarly journals Factors associated with stock out of malaria test kit in Oshana region, Namibia

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Emmanuel Magesa ◽  
Kabwebwe Honore Mitonga ◽  
Penehafo Angula
Keyword(s):  
Communicable Disease ◽  
Rapid Test ◽  
Quantitative Aspect ◽  
Factors Associated ◽  
Test Kit ◽  
Descriptive Approach ◽  
Method Approach ◽  
Insight Into ◽  
Malaria Test ◽  
Made In

Malaria continues to be a serious communicable disease whose impact on public health in Namibia is massive. Some improvement in reducing the number of malaria cases has been made in the country, but the sporadic availability of malaria diagnostic test kits (mRDT) continues to slow down government efforts to eliminate malaria in the country. Given the nature of current conditions, justification exists for a study to determine the factors associated with stock out of malaria rapid test kit (mRDT) in Namibia. Mixed method approach was employed, whereby in quantitative aspect, the study adopted a descriptive approach to acquire data from a period of five years retrospectively (2012 - 2016). To gain insight into qualitative aspects of the study, key informants at all levels of the supply chain in Oshana region were interviewed. Pharmaceutical knowledge of ordering mRDT is needed to prevent stock out of mRDT. It is a recommendation of this study that training is needed for staffs who are involved in ordering of pharmaceutical items.

The Agency of the Principal–Agent Relationship: An Opportunity for HRD

2019 ◽  
Vol 21 (3) ◽  
pp. 303-318 ◽  
Author(s):  
Rose M. Baker
Keyword(s):  
Agency Theory ◽  
Human Resource Development ◽  
Training And Development ◽  
Principal Agent ◽  
Factors Associated ◽  
Fields Of Study ◽  
Development Outcomes ◽  
Insight Into ◽  
Made In ◽  
Principal Agent Relationship

The Problem Agency theory has been empirically studied in other fields of study such as economics, political science, sociology, and management. Although a proposal for inclusion of agency theory to test training and development outcomes was made in human resource development (HRD)-related publications, little research has been conducted and published in HRD-related literature. The Solution This review of agency theory offers a description of the elements and factors associated with the principal–agent relationship that have been theorized and empirically tested in other fields of study. Much of the theoretical implications are transferable to HRD. The principal–agent relationship should be empirically tested in HRD situations and interpreted through an HRD lens. The Stakeholders The review of the principal–agent relationship in other fields is expected to benefit HRD researchers, practitioners, principals, and agents in organizations by providing insight into the orientation, elements, and influence of principal–agent relationships.

scholarly journals Magnitude and factors associated with Availability of Adequately Iodized Salt at Households of Pregnant Mothers in Wonago district, south Ethiopia

2021 ◽  
Author(s):  
Adane Tesfaye
Keyword(s):  
Iodine Deficiency ◽  
Household Income ◽  
Rapid Test ◽  
Iodized Salt ◽  
Multivariable Logistic Regression Model ◽  
Factors Associated ◽  
South Ethiopia ◽  
Monthly Household Income ◽  
Test Kit ◽  
Pregnant Mothers

Abstract Background Salt iodization is the most cost-effective, safe and sustainable strategy to eliminate iodine deficiency disorders. It is especially damaging during pregnancy and in early child hood. Adding iodine to salt provides protection from brain damage due to iodine deficiency for whole populations. However, little was known about the availability of adequately iodized salt in South Ethiopia. The aim of this study was to assess prevalence and factors associated with availability of adequately iodized salt at the households of pregnant mothers in Wonago District, South Ethiopia, 2018. Methods Community-based cross-sectional study was conducted from May 14-29, 2018 in Wonago district. Using a stratified two stage random sampling technique, a total of 604 pregnant mothers were included in the study. The level of salt iodine content was determined using the rapid field test kit, considering a value of <15 parts per million (PPM) and ≥15 PPM with the corresponding color chart on the rapid test kit for classification. Multivariable logistic regression model was fitted to identify factors associated with the availability of adequately iodized salt. Adjusted Odds Ratio (AOR) with the corresponding 95% Confidence Interval (CI) was calculated to show the strength of association. Result Availability of adequately iodized salt at households of pregnant mothers was 19.9%. House hold head, husband education, average monthly household income and time of salt addition during cooking were independently associated with adequately iodized salt availability. Accordingly, participatory male headed households [AOR=2.1(95%CI 1.08, 3.96)], women with an average monthly household income of ≥ 817 ETB [AOR=7.3(95%CI 3.03, 17.70)] and those who added salt late or after cooking during food preparation [AOR=2.17(1.08, 4.38)] were more likely to utilize adequately iodized salt. Conversely, women whose husband had no formal education were less likely [AOR=0.33(95%CI 0.11, 0.88)] to utilize iodized salt. Conclusion Compared to the recommended standard, use of adequately iodized salt among pregnant women is very low. Paternal conditions and household income level are key predictors of use of adequately iodized salt.

Will Love Tear Us Apart: Adapting the Lyrical to the Ludic

CounterText ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 217-235
Author(s):  
Gordon Calleja
Keyword(s):  
Design Process ◽  
Game Design ◽  
Digital Games ◽  
Design Decisions ◽  
The Core ◽  
Lyrical Poetry ◽  
Insight Into ◽  
Made In

This paper gives an insight into the design process of a game adaptation of Joy Division's Love Will Tear Us Apart (1980). It outlines the challenges faced in attempting to reconcile the diverging qualities of lyrical poetry and digital games. In so doing, the paper examines the design decisions made in every segment of the game with a particular focus on the tension between the core concerns of the lyrical work being adapted and established tenets of game design.

Empathy as moderator of gender differences in Chinese insurance agents' business ethical sensitivity

2017 ◽  
Vol 45 (6) ◽  
pp. 1029-1042 ◽  
Author(s):  
Na Zhang ◽  
Jian Zhang ◽  
Jing Wang
Keyword(s):  
Gender Differences ◽  
Business Ethics ◽  
Research Field ◽  
Ethical Sensitivity ◽  
Men And Women ◽  
Insurance Agents ◽  
Factors Associated ◽  
Ethics Research ◽  
The Relationship ◽  
Insight Into

To expand the business ethics research field, and to increase society's understanding of Chinese insurance agents' business ethics, we investigated how gender differences are related to agents' business ethical sensitivity and whether or not these relationships are moderated by empathy. Through a regression analysis of the factors associated with the business ethical sensitivity of 417 Chinese insurance agents, we found that gender played an important role in affecting business ethical sensitivity, and empathy significantly affected business ethical sensitivity. Furthermore, empathy had a moderating effect on the relationship between gender and business ethical sensitivity. Both men and women with strong empathy scored high on business ethical sensitivity; however, men with strong empathy had higher levels of business ethical sensitivity than did women with little empathy. The findings add to the literature by providing insight into the mechanisms responsible for the benefits of empathy in increasing business ethical sensitivity.

scholarly journals Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
David R. McIlwain ◽  
Han Chen ◽  
Maria Apkarian ◽  
Melton Affrime ◽  
Bonnie Bock ◽  
...  
Keyword(s):  
Influenza A ◽  
Rapid Test ◽  
Influenza Viruses ◽  
Qpcr Assay ◽  
Superior Performance ◽  
Qrt Pcr ◽  
Challenge Study ◽  
Test Kit ◽  
2009 H1n1 ◽  
B Test

Abstract Background Influenza places a significant burden on global health and economics. Individual case management and public health efforts to mitigate the spread of influenza are both strongly impacted by our ability to accurately and efficiently detect influenza viruses in clinical samples. Therefore, it is important to understand the performance characteristics of available assays to detect influenza in a variety of settings. We provide the first report of relative performance between two products marketed to streamline detection of influenza virus in the context of a highly controlled volunteer influenza challenge study. Methods Nasopharyngeal swab samples were collected during a controlled A/California/2009/H1N1 influenza challenge study and analyzed for detection of virus shedding using a validated qRT-PCR (qPCR) assay, a sample-to-answer qRT-PCR device (BioMerieux BioFire FilmArray RP), and an immunoassay based rapid test kit (Quidel QuickVue Influenza A + B Test). Results Relative to qPCR, the sensitivity and specificity of the BioFire assay was 72.1% [63.7–79.5%, 95% confidence interval (CI)] and 93.5% (89.3–96.4%, 95% CI) respectively. For the QuickVue rapid test the sensitivity was 8.5% (4.8–13.7%, 95% CI) and specificity was 99.2% (95.6–100%, 95% CI). Conclusion Relative to qPCR, the BioFire assay had superior performance compared to rapid test in the context of a controlled influenza challenge study.

New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm

2013 ◽  
Vol 394 (1) ◽  
pp. 89-95 ◽  
Author(s):  
Mamta Jaiswal ◽  
Eyad Kalawy Fansa ◽  
Radovan Dvorsky ◽  
Mohammad Reza Ahmadian
Keyword(s):  
Quantitative Analysis ◽  
Bound State ◽  
Molecular Switch ◽  
Nucleotide Exchange ◽  
Gtp Binding ◽  
Switch Mechanism ◽  
Rho Family ◽  
Rho Family Proteins ◽  
Insight Into ◽  
Made In

Abstract Major advances have been made in understanding the structure, function and regulation of the small GTP-binding proteins of the Rho family and their involvement in multiple cellular process and disorders. However, intrinsic nucleotide exchange and hydrolysis reactions, which are known to be fundamental to Rho family proteins, have been partially investigated in the case of RhoA, Rac1 and Cdc42, but for others not at all. Here we present a comprehensive and quantitative analysis of the molecular switch functions of 15 members of the Rho family that enabled us to propose an active GTP-bound state for the rather uncharacterized isoforms RhoD and Rif under equilibrium and quiescent conditions.

Formation, translocation and resolution of Holliday junctions during homologous genetic recombination

1995 ◽  
Vol 347 (1319) ◽  
pp. 21-25 ◽  
Keyword(s):  
Molecular Mechanisms ◽  
Genetic Recombination ◽  
Holliday Junctions ◽  
The Novel ◽  
E Coli ◽  
The Past ◽  
Endonucleolytic Cleavage ◽  
Insight Into ◽  
Made In

Over the past three or four years, great strides have been made in our understanding of the proteins involved in recombination and the mechanisms by which recombinant molecules are formed. This review summarizes our current understanding of the process by focusing on recent studies of proteins involved in the later steps of recombination in bacteria. In particular, biochemical investigation of the in vitro properties of the E. coli RuvA, RuvB and RuvC proteins have provided our first insight into the novel molecular mechanisms by which Holliday junctions are moved along DNA and then resolved by endonucleolytic cleavage.

Recent progress in the freeze-etching technique

1971 ◽  
Vol 261 (837) ◽  
pp. 121-131 ◽  
Keyword(s):  
High Vacuum ◽  
Molecular Size ◽  
Etching Technique ◽  
Structural Distortions ◽  
Shadow Casting ◽  
Structural Details ◽  
Freeze Etching ◽  
The One ◽  
Insight Into ◽  
Made In

The freeze-etching technique must be improved if structures at the molecular size level are to be seen. The limitations of the technique are discussed here together with the progress made in alleviating them. The vitrification of living specimens is limited by the fact that very high freezing rates are needed. The critical freezing rate can be lowered on the one hand by the introduction of antifreeze agents, on the other hand by the application of high hydrostatic pressure. The fracture process may cause structural distortions in the fracture face of the frozen specimen. The ‘double-replica’ method allows one to evaluate such artefacts and provides an insight into the way that membranes split. During etching there exists the danger of contaminating the fracture faces with condensable gases. Because of specimen temperatures below —110 °C, special care has to be taken in eliminating water vapour from the high vacuum. An improvement in coating freeze-etched specimens has resulted from the application of electron guns for evaporation of the highest melting-point metals. If heat transfer from gun to specimen is reduced to a minimum, Pt, Ir, Ta, W and C can be used for shadow casting. Best results are obtained with Pt-C and Ta-W . With the help of decoration effects Pt-C shadow castings give the most information about the fine structural details of the specimen.

An analysis of the forfeiture regime under the anti-money laundering law

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Aspalella A. Rahman
Keyword(s):  
Money Laundering ◽  
Secondary Data ◽  
Primary Sources ◽  
Court Cases ◽  
Sources Of Information ◽  
Content Type ◽  
Terrorism Financing ◽  
Bona Fide ◽  
Descriptive Approach ◽  
Insight Into

Purpose This paper aims to analyze the forfeiture regime under the Malaysian anti-money laundering law. Apart from discussing the relevant provisions, several court cases also were examined to identify the problems which arise in the implementation of such a powerful forfeiture regime. Design/methodology/approach This paper mainly relies on statutes and court cases as its primary sources of information. It is supported by secondary data to justify the analysis. This paper also used analytical descriptive approach to analyze relevant forfeiture provisions from statutes and to examine current court cases regarding the implementation of the forfeiture regime. Findings The Anti-Money Laundering, Anti-Terrorism Financing and Proceeds of Unlawful Activities Act (AMLATFPUAA) provides comprehensive procedures for the forfeiture of criminal proceeds. Any limitations of the previous statutory legislations have been addressed, and more importantly, the AMLATFPUAA introduces more powerful and innovative measures that can facilitate the recovery of illegal proceeds from money laundering and any other serious crimes. The AMLATFPUAA also provides avenue for the bona fide third parties to contest the forfeiture order. However, it appears that such right is not easy to be enforced. Originality/value This paper provides an analysis of the forfeiture regime under Malaysian anti-money laundering laws. It is hoped that the content of this paper can provide some insight into this particular area for enforcement authorities, practitioners, academics, policymakers and legal advisers not only in Malaysia but also elsewhere. The findings of this paper also expose any weakness or lacunae in the aspects of application and implementation of the forfeiture regime. Thus, more effective and workable legal solution especially on the issue of civil forfeiture of criminal assets could be considered for further accomplishment.

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