scholarly journals Sodium fluoride as an ascaricide for swine raised on the ground

1969 ◽  
Vol 31 (2) ◽  
pp. 190-202
Author(s):  
Radamee Orlandi ◽  
Fernando E. Armstrong
Keyword(s):  
Sodium Fluoride ◽  
Ascaris Lumbricoides ◽  
Experimental Period ◽  
Growing Pigs ◽  
Control Group ◽  
Repeated Treatment ◽  
Treatment Trial ◽  
Cent Sodium ◽  
Group A ◽  
Group B

Two trials were conducted to test the value of sodium fluoride as an ascaricide for growing pigs kept on infested grounds. The ability of the drug to kep animals free from ascarides and the possible toxicity upon repeated treatment were also studied. Three groups of animals similar as to breeding, weight and age were used in Trial I. Group "A" served as control. Group "B" received 0.2 gm. of phenothiazine per pound or bodily weight and group "C" one per cent sodium fluoride mixed with ground feed. Except for slight variations in the procedure and the elimination of the phenothiazine treatment, Trial II was conducted in the same manner. The effectiveness of the different treatments given during the experimental period was measured by statistical analyses of the number of ascarid and non-ascarid eggs per gram of fresh rectal feces secured once every week, by the weight gains made by each animal, and by the number of Ascaris worms found upon visceral examination. The results obtained suggest that sodium fluoride at the rate of one per cent mixed in the feed every three weeks is a very satisfactory drug for killing Ascaris lumbricoides suis found in growing pigs raised on the ground. When fed repeatedly to growing pigs for periods of from 3 to 4 months it was effective in keeping the animals clean, with no toxic effects whatsoever. Phenothiazine at the rate of 0.2 gm. per pound of bodily weight administered every three weeks was found to be unreliable as an ascaricide. The data obtained during the two trials made suggest that sodium fluoride is specific against Ascaris lumbricoides suis.

scholarly journals INVESTIGATION ON THE COUNTERACTING EFFECT OF SPIRULINA AGAINST POTENTATED SULFONAMIDE’S (COTRIM DS®) SIDE EFFECTS IN RAT

2013 ◽  
Vol 10 (1-2) ◽  
pp. 81-86 ◽  
Author(s):  
M. K. Islam ◽  
S. Akter ◽  
S. Bala ◽  
M. Z. Hossain ◽  
M.S. Akter
Keyword(s):  
Hematological Parameters ◽  
Experimental Period ◽  
Treated Group ◽  
Control Group ◽  
High Dose ◽  
Spirulina Maxima ◽  
Liver And Kidney ◽  
Group A ◽  
Group B ◽  
And Control

An experiment was conducted to investigate the counteracting effects of spirulina in Long Evans rats exposed to oral potentiated sulfonamide administration. 20 rats were randomly assigned into four equal groups (A, B, C and D) and were fed with standard broiler pellet (25g/rat/day) throughout the experimental period of 60 days. Rats of Group A were fed only with pellet without any experimental diet and were defined as control. Rats  of Group B were treated with potentiated sulfonamide @ 96 mg/rat/day orally whereas Group C was treated with potentiated sulfonamide @ 96 mg/rat/day plus spirulina (Spirulina maxima) @ 50 mg/rat/day orally (low dose spirulina). In Group D, potentiated sulfonamide and spirulina (Spirulina maxima) were given through feed @ 96 mg/rat/day and @ 100 mg/rat/day (high dose spirulina) respectively. Hematological parameters (TEC, Hb and absolute count of lymphocyte, neutrophil and eosinophil) and hispathological profile of liver and kidney were recorded. The investigation revealed that the oral administration of sulfonamide significantly (p<0.01) decreased the TEC (5.93±0.24) value, number of lymphocyte (581.76±3.70) and neutrophil (581.76±3.70) compared to other treated groups and control group. On the other hand significant (p<0.01) increase (422.86±2.34) in eosinophil population has been found in rats fed on sulfonamide irrespective of spirulina supplementation on the final day of experiment compared to other treated group and control group. From this experiment it is evidenced that spirulina has a potential counteracting effect against sulfonamide. Histopathology of kidney and liver was done at the end of experiment (60 days) and no significant change was found except in the kidney of Group B and C.DOI: http://dx.doi.org/10.3329/bjvm.v10i1-2.15650

scholarly journals Effects of triclabendazole and nitroxynil on EPG, hematological parameters and body weight against fascioliasis in goats at government goat development farm, Sylhet, Bangladesh

2016 ◽  
Vol 5 (2) ◽  
pp. 46-51 ◽  
Author(s):  
S Khanam ◽  
MS Islam ◽  
M Aktaruzzaman ◽  
MA Hossain ◽  
MM Hossain ◽  
...  
Keyword(s):  
Body Weight ◽  
Dose Rate ◽  
Hematological Parameters ◽  
Experimental Period ◽  
The Body ◽  
Control Group ◽  
Infected Control Group ◽  
Group A ◽  
Group B ◽  
And Control

The study was conducted to evaluate the effects of triclabendazole and nitroxynil against fascioliasis in goat for a period of 28 days on 20 black bengal goats. Among hundred goats, twenty were selected for this study which was suffering from liver fluke (Fasciola gigantica) infection and were marked by tagging. Twenty goats were randomly divided into four groups (A, B, C and D) where each group comprising of five goats. Group A were treated with tablet fasinex (triclabendazole, Novartis Ltd, Bangladesh) orally at the dose rate of 12 mgkg-1body weight, group B were treated with acinex (triclabendazole, ACI Ltd, Bangladesh) orally at the dose rate of 12 mgkg-1body weight and group C were treated with nitronex injection (nitroxynil, Renata Ltd, Bangladesh) subcutaneously at the dose rate of 10 mgkg-1 body weight. Goats of group D was kept as infected control group without giving any treatment. A significant (P<0.01) reduction of egg per gram (EPG) count was found on 7th, 14th, 21st and 28th days of treated goats of group A, B and C, respectively. The EPG count of control group were significantly (P<0.01) increased 7 day onwards up to experimental period. Reduction of mean EPG on 7th, 14th, 21st and 28th day after treatment in group A, B and C were 81.48%, 81.25% and 83.04%, respectively, whereas in control group the mean EPG were 22.43%. Of the hematological parameters, TEC, Hb and PCV values were lower on day 0 but turned to increase (p<0.01) on day 28 of the study. On the other hand, ESR and TLC were higher before treatment (day 0) but decreased significantly (p<0.01) on day 28.The body weight increased significantly (P<0.01) after treatments in group A, B and C respectively except untreated control. This result may indicate that three commercial anthelmintics contain triclabendazole and nitroxynil against fascioliasis in goat and nitroxynil have higher efficacies on egg per gram (EPG), hematological parameters and body weight against fascioliasis in goat. Additional detailed studies are required to prevent and control of fascioliasis in goats by using a routine prophylactic anthelmintics measurement.International Journal of Natural Sciences (2015), 5(2) 46-51

scholarly journals Effects of peroral supplementation of different forms of zinc on the ruminal mucosa of goat kids – a morphometric study

2013 ◽  
Vol 82 (4) ◽  
pp. 399-403 ◽  
Author(s):  
Julius Černík ◽  
Leoš Pavlata ◽  
Alena Pechová ◽  
Ľubica Mišurová ◽  
Olga Jokverová ◽  
...  
Keyword(s):  
Zinc Supplementation ◽  
Experimental Period ◽  
The Other ◽  
Morphometric Study ◽  
Control Group ◽  
Group A ◽  
Group B ◽  
Group D

The aim of the study was to identify the effect of supplementation of various forms of zinc on the ruminal mucosa and dimensions of ruminal papillae in 6-month-old goat kids. The experimental period lasted from weaning to slaughter (4 months). All 20 kids divided into four groups of five animals, were fed with the same feeding dose, which was different only in the quantity and form of zinc. Control group was without additional zinc supplementation (group A), the other groups were supplemented with zinc in the form of ZnO (group B), zinc in the form of chelate (group C) and zinc in the form of lactate (group D). Samples for histopathological and morphometric examination were collected after the slaughter of all animals from the bottom of saccus ruminis ventralis everytime from the same place. Significant differences were reported within the comparison of the length of ruminal papillae between groups B and C (P = 0.026) and B and D (P = 0.040), within the comparison of the width of ruminal papillae between groups A and D (P = 0.020) and within the comparison of the intensity of keratinisation of the mucosa of ruminal papillae between groups A and B (P = 0.034), A and C (P = 0.038) and A and D (P = 0.001). Histopathological and morphometric examination of ruminal mucosa indicated that the ruminal papillae of kids supplemented with zinc in the form of ZnO (group B) were better developed compared to the other groups. This result indicates better utilisation of the supplemented zinc in the form of ZnO.

scholarly journals THE EFFECTIVENESS OF IPAD USE IN PROMOTING STUDENT ACHIEVEMENT IN A SECONDARY SCHOOL IN SAUDI ARABIA

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Badi Aldossry
Keyword(s):  
Secondary School ◽  
Teaching And Learning ◽  
Experimental Period ◽  
Control Group ◽  
Traditional Methods ◽  
Post Test ◽  
Quasi Experimental ◽  
Group A ◽  
The Mean ◽  
Group B

<p>The Ministry of Education in Saudi Arabia has used technology to support teaching and learning in Saudi's school system to meet the requirements of the National Transformation Program under Vision 2030. There are different kinds of technology which can enhance the effectiveness of the teaching and learning of mathematics, such as the iPad. This paper presents results of primary research investigating the effect of using iPads in enhancing student achievement in a Saudi secondary school. A quasi-experimental design was used to determine the effect of using an iPad on students' achievement in mathematics across two tenth grade classes (A and B) for two months. In the first month, students of group A used the iPad as a learning tool (treatment group), while students of group B used traditional methods as learning tools (control group). In the second month of the quasi-experimental period, group A became the control group using traditional methods, while group B became the treatment group using the iPad to learn mathematics. At the start of the experiment, a pre-test was completed, and the first post-test occurred one month later, then the treatment was switched. After two months at the end of the quasi-experimental period, both groups had taken the second post-test. Cronbach's alpha coefficient measured the reliability of these tests, with the first test at 0.784 and the second test at 0.792, regarded as very high (close to 1.00). Thus, the tests' reliability and credibility were confirmed. Nine comparisons of the means were used to see if a significant statistical difference between the mean of the two groups or within a group existed, by using the SPSS t-test. After comparing the mean of ‘within-group A’, ‘within group B’, and ‘group A and group B’, it was seen that using the iPad made a statistically significant difference (p&lt;0.05) in students' achievements compared to traditional methods. The study summarises the main results and specific recommendations are provided.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0631/a.php" alt="Hit counter" /></p>

Clinical effect of Suvarna Bindu Prashan

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Patil Aniket ◽  
Dindore Pallavi ◽  
Arbar Aziz ◽  
Kadam Avinash ◽  
Saroch Vikas
Keyword(s):  
Physical Health ◽  
Eating Habits ◽  
Control Group ◽  
Inform Consent ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Immune Booster ◽  
Mental And Physical Health ◽  
Apparently Healthy

The quest for excellence in mental and physical health is not new. We find various references and formulations in Ayurvedic classics meant for promoting mental and physical health of a child. Suvarna Prashan is one of the formulations explained in age old Ayurvedic classic Kashyap Samhita. This formulation is very widely used now days as a memory and immune booster for children. But there is very little systematic documented study which can be used to evaluate the efficacy of the formulation. Suvarna Bhasma was prepared in Ayurved Rasayani Pharmacy, Pune. Madhu and Ghrita were collected from KLE Ayurveda Pharmacy, Belgaum. Suvarna Bindu Prashan was prepared in KLE Ayurved pharmacy, Belgaum. It contains Suvarna Bhasma, Ghrita and Madhu. Twenty apparently healthy male and female children with age group of three to four years were ready to sign inform consent form were selected into two groups each. Subjects in Group A received Suvarna Bindu Prashan where as Group B (Control group) did not receive any treatment. Both the groups were observed for six months. Children in Suvarna Bindu Prashan group showed significant reduction in the scores of eating habits, behavior, mood, temperament and scores of event of illness. However there was no significant difference in the score of sleeping habit. There was significant increase in IQ percentage.

scholarly journals Microecological preparation combined with an modified low-carbon diet improves glucolipid metabolism and cardiovascular complication in obese patients

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Jianguo Liu ◽  
Liehui Xiao ◽  
Hezhongrong Nie ◽  
Yong Pan ◽  
Yan Liu ◽  
...  
Keyword(s):  
Intestinal Barrier ◽  
Intestinal Barrier Function ◽  
Control Group ◽  
Obese Patients ◽  
Carotid Atherosclerotic Plaque ◽  
Low Carbon ◽  
Balanced Diet ◽  
Group A ◽  
Group B ◽  
Control Group Group

Abstract Objective To investigate the impact of microecological preparation combined with modified low-carbon diet on the glucolipid metabolism and cardiovascular complication in obese patients. Methods From August 2017 to July 2020, 66 obese patients were recruited, and administrated with an modified low-carbon diet with (group A) or without (Group B) microecology preparation and a balanced diet in control group (group C) for 6 months. Meanwhile, 20 volunteers administrated with a balanced diet were recruited as the healthy control group (group D). Results After 6-month intervention, obese subjects in group A and B showed significant improvement of body and liver fat mass, reduction of serum lipid levels, intestinal barrier function markers, insulin resistance index (IRI), high blood pressure (HBP) and carotid intima thickness, as compared with subjects in group C. More importantly, subjects in group A had better improvement of vascular endothelial elasticity and intimal thickness than subjects in group B. However, these intervention had no effect on carotid atherosclerotic plaque. Conclusion Administration of microecological preparation combined with modified low-carbon diet had better improvement of intestinal barrier function, glucose and lipid metabolism, and cardiovascular complications than low-carbon diet in obese patients, but the effect of a simple low-carb diet on carotid atherosclerotic plaque need to be further addressed.

scholarly journals Effects of different thermal insulation methods on the nasopharyngeal temperature in patients undergoing laparoscopic hysterectomy: a prospective randomized controlled trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guanyu Yang ◽  
Zefei Zhu ◽  
Hongyu Zheng ◽  
Shifeng He ◽  
Wanyue Zhang ◽  
...  
Keyword(s):  
Thermal Insulation ◽  
Primary Outcome ◽  
Controlled Trial ◽  
Laparoscopic Hysterectomy ◽  
Control Group ◽  
Prospective Randomized Controlled Trial ◽  
Warming Blanket ◽  
Group A ◽  
Insulation Effect ◽  
Group B

Abstract Background This study explored the comparison of the thermal insulation effect of incubator to infusion thermometer in laparoscopic hysterectomy. Methods We assigned 75 patients enrolled in the study randomly to three groups: Group A: Used warming blanket; group B: Used warming blanket and infusion thermometer; group C: Used warming blanket and incubator. The nasopharyngeal temperature at different time points during the operation served as the primary outcome. Results The nasopharyngeal temperature of the infusion heating group was significantly higher than that of the incubator group 60 min from the beginning of surgery (T3): 36.10 ± 0.20 vs 35.81 ± 0.20 (P<0.001)90 min from the beginning of surgery (T4): 36.35 ± 0.20 vs 35.85 ± 0.17 (P<0.001). Besides, the nasopharyngeal temperature of the incubator group was significantly higher compared to that of the control group 60 min from the beginning of surgery (T3): 35.81 ± 0.20 vs 35.62 ± 0.18 (P<0.001); 90 min from the beginning of surgery (T4): 35.85 ± 0.17 vs 35.60 ± 0.17 (P<0.001). Regarding the wake-up time, that of the control group was significantly higher compared to the infusion heating group: 24 ± 4 vs 21 ± 4 (P = 0.004) and the incubator group: 24 ± 4 vs 22 ± 4 (P = 0.035). Conclusion Warming blanket (38 °C) combined infusion thermometer (37 °C) provides better perioperative thermal insulation. Hospitals without an infusion thermometer can opt for an incubator as a substitute. Trial registration This trial was registered with ChiCTR2000039162, 20 October 2020.

scholarly journals The Bone Buttress Theory: The Effect of the Mechanical Loading of Bone on the Osseointegration of Dental Implants

Biology ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 12
Author(s):  
David Chavarri-Prado ◽  
Aritza Brizuela-Velasco ◽  
Ángel Álvarez-Arenal ◽  
Markel Dieguez-Pereira ◽  
Esteban Pérez-Pevida ◽  
...  
Keyword(s):  
Dental Implants ◽  
Mechanical Loading ◽  
Bone Growth ◽  
Bone Matrix ◽  
Test Group ◽  
Control Group ◽  
Group A ◽  
Bone To Implant Contact ◽  
The Stability ◽  
Group B

Objectives: To determine the effect of mechanical loading of bone on the stability and histomorphometric variables of the osseointegration of dental implants using an experimental test in an animal model. Materials and Methods: A total of 4 human implants were placed in both tibiae of 10 New Zealand rabbits (n = 40). A 6-week osseointegration was considered, and the rabbits were randomly assigned to two groups: Group A (Test group) included 5 rabbits that ran on a treadmill for 20 min daily during the osseointegration period; Group B (Controls) included the other 5 that were housed conventionally. The monitored variables were related to the primary and secondary stability of the dental implants (implant stability quotient—ISQ), vertical bone growth, bone to implant contact (BIC), area of regenerated bone and the percentage of immature matrix. Results: The results of the study show a greater vertical bone growth (Group A 1.26 ± 0.48 mm, Group B 0.32 ± 0.47 mm, p < 0.001), higher ISQ values (Group A 11.25 ± 6.10 ISQ, 15.73%; Group B 5.80 ± 5.97 ISQ, 7.99%, p = 0.006) and a higher BIC (Group A 19.37%, Group B 23.60%, p = 0.0058) for implants in the test group, with statistically significant differences. A higher percentage of immature bone matrix was observed for implants in the control group (20.68 ± 9.53) than those in the test group (15.38 ± 8.84) (p = 0.108). A larger area of regenerated bone was also observed for the test implants (Group A 280.50 ± 125.40 mm2, Group B 228.00 ± 141.40 mm2), but it was not statistically significant (p = 0.121). Conclusions: The mechanical loading of bone improves the stability and the histomorphometric variables of the osseointegration of dental implants.

Glycine and L-Arginine supplementation ameliorates gastro-duodenal toxicity in a rat model of NSAID (Diclofenac)-gastroenteropathy via inhibition of oxidative stress

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Akinleye Stephen Akinrinde ◽  
Halimot Olawalarami Hameed
Keyword(s):  
Oxidative Stress ◽  
Total Protein ◽  
Therapeutic Index ◽  
Control Treatment ◽  
Control Group ◽  
Protective Effects ◽  
Serum Total Protein ◽  
Significant Amelioration ◽  
Group A ◽  
Group B

Abstract Objectives This study examined the possible protective roles of exogenous glycine (Gly) and L-Arginine (l-Arg) against Diclofenac (DIC)-induced gastro-duodenal damage in rats. Methods Rats were divided into Group A (control), Group B (DIC group) and Groups C–F which were pre-treated for five days with Gly1 (250 mg/kg), Gly2 (500 mg/kg), l-Arg1 (200 mg/kg) and l-Arg2 (400 mg/kg), respectively, before co-treatment with DIC for another three days. Hematological, biochemical and histopathological analyses were then carried out. Results DIC produced significant (p<0.05) reduction in PCV (13.82%), Hb (46.58%), RBC (30.53%), serum total protein (32.72%), albumin (28.44%) and globulin (38.01%) along with significant (p<0.05) elevation of serum MPO activity (83.30%), when compared with control. In addition, DIC increased gastric H2O2 and MDA levels by 33.93 and 48.59%, respectively, while the duodenal levels of the same parameters increased by 19.43 and 85.56%, respectively. Moreover, SOD, GPx and GST activities in the DIC group were significantly (p<0.05) reduced in the stomach (21.12, 24.35 and 51.28%, respectively) and duodenum (30.59, 16.35 and 37.90%, respectively), compared to control. Treatment with Gly and l-Arg resulted in significant amelioration of the DIC-induced alterations although l-Arg produced better amelioration of RBC (29.78%), total protein (10.12%), albumin (9.93%) and MPO (65.01%), compared to the DIC group. The protective effects of both amino acids against oxidative stress parameters and histological lesions were largely similar. Conclusions The data from this study suggest that Gly or l-Arg prevented DIC-induced gastro-duodenal toxicity and might, therefore be useful in improving the therapeutic index of DIC.

scholarly journals Clinical and Microbiological Evaluation of Local Doxycycline and Antimicrobial Photodynamic Therapy during Supportive Periodontal Therapy: A Randomized Clinical Trial

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 277
Author(s):  
Raluca Cosgarea ◽  
Sigrun Eick ◽  
Ionela Batori-Andronescu ◽  
Søren Jepsen ◽  
Nicole B. Arweiler ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Bacterial Species ◽  
Periodontal Therapy ◽  
Local Drug Delivery ◽  
Control Group ◽  
Periodontal Pathogens ◽  
Supportive Periodontal Therapy ◽  
Group A ◽  
Group B ◽  
Attachment Level

The aim of this study was to evaluate the clinical and microbiological effects of subgingival instrumentation (SI) alone or combined with either local drug delivery (LDD) or photodynamic therapy (PDT) in persistent/recurrent pockets in patients enrolled in supportive periodontal therapy (SPT). A total of 105 patients enrolled in SPT were randomly treated as follows: group A (n = 35): SI +PDT and 7 days later 2nd PDT; group B (n = 35): SI+LDD; group C (n = 35): SI (control). Prior intervention, at 3 and 6 months after therapy, probing pocket depths, clinical attachment level, number of treated sites with bleeding on probing (n BOP), full mouth plaque and bleeding scores (gingival bleeding index, %BOP) were recorded. At the same time points, 8 periodontopathogens were quantitatively determined. All three treatments resulted in statistically significant improvements (p < 0.05) of all clinical parameters without statistically significant intergroup differences (p > 0.05). Several bacterial species were reduced in both test groups, with statistically significantly higher reductions for LDD compared to PDT and the control group. In conclusion, the present data indicate that: (a) In periodontal patients enrolled in SPT, treatment of persistent/recurrent pockets with SI alone or combined with either PDT or LDD may lead to comparable clinical improvements and (b) the adjunctive use of LDD appears to provide better microbiological improvements for some periodontal pathogens than SI alone or combined with PDT.

Sign in / Sign up

Export Citation Format

Share Document