scholarly journals Effect of Intracanal Cryotherapy and Negative Irrigation Technique on Postendodontic Pain

2016 ◽  
Vol 17 (12) ◽  
pp. 990-996 ◽  
Author(s):  
Talal Al-Nahlawi ◽  
Talaat Abo Hatab ◽  
Mahmoud Abd Alrazak ◽  
Ahmad Al-Abdullah
Keyword(s):  
Negative Pressure ◽  
Root Canal ◽  
Room Temperature ◽  
Control Group ◽  
P Value ◽  
Group Iii ◽  
Single Visit ◽  
Single Root ◽  
Group I ◽  
The Social

ABSTRACT Aim To evaluate the effect of intracanal cryotherapy with negative pressure irrigation (EndoVac) on postendodontic pain after vital single-visit root canal treatment (RCT). Materials and methods A total of 75 single-rooted teeth with single root canal were treated endodontically. After root canal preparation with Protaper Universal rotary system and irrigation, teeth were divided randomly into three groups (n = 25) according to additional irrigation protocol as follows: Group I: No additional irrigation was applied (control); group II: A 20 mL of room temperature saline was irrigated during 5 minutes using EndoVac, and group III: A 20 mL of 2 to 4°C cold saline was irrigated during 5 minutes using EndoVac. Pain levels were assessed by visual analog scale (VAS) and verbal evaluation of pain questionnaire after 6, 12, 24, 48 hours, and 7 days of canal obturation. The data were then analyzed using Statistical Package for the Social Sciences (SPSS) 13.0 using Kruskal–Wallis and Mann–Whitney U tests at p-value of 0.05. Results The results showed that pain levels were high in groups I and II after 6 hours that decreased with time to almost diminish after 1 week, and on the other hand, group III showed no pain among different monitoring periods. Also pain levels in groups II were lower compared with group I after only 6 hours, with significance p < 0.05. Conclusion Postendodontic pain presented with highest values after 6 hours of treatment and reduced to almost nil after 1 week. Intracanal cryotherapy eliminated postendodontic pain clinically. Negative pressure reduced postendodontic pain after 6 hours of treatment. Clinical significance The outcome of this study indicates that the use of intracanal cryotherapy technique with negative pressure irrigation eliminates postendodontic pain after single-visit RCTs. How to cite this article Al-Nahlawi T, Abo Hatab T, Abd Alrazak M, Al-Abdullah A. Effect of Intracanal Cryotherapy and Negative Irrigation Technique on Postendodontic Pain. J Contemp Dent Pract 2016;17(12):990-996.

Effects of Garcinia Cambogia on the Weights of Normal Albino Mice

2021 ◽  
Vol 15 (11) ◽  
pp. 2956-2957
Author(s):  
Gul Afshan ◽  
Ponum Mirani ◽  
Imtiaz Aslam ◽  
Sobia Ibrahim
Keyword(s):  
Control Group ◽  
P Value ◽  
Distilled Water ◽  
Garcinia Cambogia ◽  
Group Iii ◽  
Smart Drugs ◽  
Group I ◽  
Final Weight ◽  
Albino Mice ◽  
Experimental Group

Aim: Effects of available weight reducing drugs on the weights of a normal albino mice. Methodology: In this study, total 39 adult albino mice were used and were divided in three groups containing 13 animals in each. Group I served as control and was given 1 ml of distilled water once a day for 8 weeks. Group II and Group III served as experimental group and mice in these groups were given 0.5 mg of Slim Smart and Ultra Slim Plus drugs dissolved in 1 ml of distilled water respectively once a day for 8 weeks. To support these results weights of kidneys were also measured and relative tissue width index was calculated and compared with control group. Results: The weight of the animals increased in the experimental groups as compared to the control group. The overall difference for final weight among three groups was highly significant with p-value <0.01. When final weight compared group wise, the experimental groups had significantly higher weight as compared to control with p-values <0.01and 0.028 Conclusion: Both Ultra Slim Plus and Slim Smart drugs cause weight to increase in the individuals who are not obese and have BMI in normal range Keywords: Weight loss, Garcinia Cambodia, kidney, Albino mice

scholarly journals Comparative Evaluation of Apical Sealing Ability of Different Obturation Techniques by Confocal Microscopy: An In Vitro Study

2020 ◽  
Vol 8 (02) ◽  
pp. 55-59
Author(s):  
Reetu Arora ◽  
Yogesh Kumar ◽  
Neetu Jindal ◽  
Renu Aggarwal ◽  
Kavneet Takhar
Keyword(s):  
Root Canal ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Group Iv ◽  
Control Group ◽  
Group Vi ◽  
Group V ◽  
Group Iii ◽  
Group I

Abstract Introduction The aim of obturation in the root canal is to completely seal the canal space to eliminate all the portals of entry and exit between root canal and periodontal space. Various techniques have been developed to achieve a hermetic seal. Materials and Methods As many as 150 extracted human maxillary central incisors were taken for the study. Biomechanical preparation was done up to F5 protaper file. According to different obturation techniques, samples were divided into six groups, keeping 30 samples in experimental and 15 samples in control groups. Group I–Lateral Condensation, Group II–Thermafil, Group III–Beefill, Group IV–GuttaFlow, Group V–Positive Control group, Group VI–Negative Control group. After obturation, the samples were immersed in 2% Rhodamine-B dye for 24 hours. Each sample was longitudinally sectioned to examine under confocal laser scanning microscope. Statistical Analysis The results were evaluated with ANOVA and posthoc Tukey honest significant difference (HSD) comparison test. Results The mean values of dye penetration of different groups were Group I (Lateral Condensation) 1.51 ± 0.451, Group II (Thermafil) 0.918 ± 0.399, Group III (Beefill) 1.30 ± 0.559. Group IV (GuttaFlow) 0.655 ± 0.396, Group V (Positive Control group) 1.96 ±0.046, Group VI (Negative Control group) 0 ± 0. The lowest mean value of apical microleakage was found in GuttaFlow amongst all experimental groups. Conclusion It can be concluded that the GuttaFlow obturating material exhibited better apical sealing ability with canal walls.

An in vitro Evaluation of Microtensile Bond Strength of Resin-based Sealer with Dentin Treated with Diode and Nd:YAG Laser

2013 ◽  
Vol 14 (2) ◽  
pp. 183-187 ◽  
Author(s):  
G Anil Kumar ◽  
Maneesha Das ◽  
Sindhu Ramesh ◽  
Surendranath Garapati
Keyword(s):  
Bond Strength ◽  
Nd:Yag Laser ◽  
Root Canal ◽  
Smear Layer ◽  
Control Group ◽  
Microtensile Bond Strength ◽  
Group Iii ◽  
Group I ◽  
Ah Plus

ABSTRACT Background Smear layer is a negative factor which prevents adhesion of the filling material to the dentinal walls. Recent advances in dental research have incorporated lasers as a potential adjunct in root canal treatment by removing the smear layer before filling the root canal system, enhancing the adhesion of sealers to dentin and improving the sealing ability. Aim To evaluate the microtensile bond strength of AH-Plus resin-based sealer to dentin after treatment with 980 nm diode and 1,064 nm neodymium-doped:yttrium aluminum garnet (Nd:YAG) laser in vitro. Materials and methods Thirty specimens prepared for three groups namely group I (control), group II (980 nm diode–lased specimens) and group III (Nd:YAG–lased specimens). One tooth from each group was observed under scanning electron microscope for evaluation of intracanal root dentin morphology. Remaining specimens were used for making microsections by hard tissue microtome. Specimens for groups II and III were lased with 980 nm diode and 1,064 nm Nd:YAG laser. AH Plus sealer was applied onto specimens and mounted onto Instron universal testing machine for microtensile bond strength testing. Results were subjected to statistical analysis using one-way analysis of variance (ANOVA) and Tukey's test. Results Group III Nd:YAG had maximum mean microtensile bond strength values (11.558 ± 0.869), followed by group II diode (9.073 ± 0.468) and group I control (6.05 ± 0.036). Statistically significant differences were seen among all the groups. SEM analysis shows removal of smear layer in both groups II and III. Conclusion Both Nd:YAG and diode laser were more effective than control group in improving the microtensile bond strength of AH Plus sealer to dentin. Clinical significance Lasers have the potential to increase the adhesiveness of root canal sealer to dentin surface, thereby improving the quality of root canal obturation. How to cite this article Maneesha D, Anil KG, Sindhu R, Surendranath G, Deepak S. An in vitro Evaluation of Microtensile Bond Strength of Resin-based Sealer with Dentin Treated with Diode and Nd:YAG Laser. J Contemp Dent Pract 2013;14(2): 183-187.

Effect of Visual Experience on Spatial Learning of Rats

2020 ◽  
Keyword(s):  
Visual Information ◽  
Movement Pattern ◽  
Visual Deprivation ◽  
Male Rats ◽  
Control Group ◽  
P Value ◽  
Adult Rats ◽  
Group Iii ◽  
Group I ◽  
Significant Difference

Background: Visual information acquired through observation plays a pivotal role in learning a movement pattern and motor control. Objectives: This study aimed to analyze the effect of visual deprivation on learning in rats. Methods: The study sample consisted of 12 male rats, divided into three groups. Group I consisted of four rats and was considered the control group. Transection of the two optic nerves was performed on rats of group II on the seventh day after birth and group III on the seventh week after birth to develop the early blind and late blind models, respectively. A T-shaped maze device was utilized to evaluate the learning behavior of rats. Rats of groups II and III were blinded by the optic nerve surgery. In total, 20 trials per day were conducted for nine consecutive days, in which the time and number of correct arm entries were recorded. The ANOVA and Kruskal-Wallis tests were employed to analyze the results in SPSS software (version 16.0). A p-value of less than 0.05 was considered statistically significant. Results: There was a significant difference between the three groups regarding the number of correct arm entries on days one, three, and seven (P<0.05). There was also a significant difference between the three groups regarding how long it took them to enter the target box on days two and three (P<0.05). Group III had a lower number of entries to the target box and it took them a significantly longer time to enter the target box, compared to the other groups. Conclusion: According to the results, visual deprivation may affect the learning of rats during the early days; however, their learning levels increased over the following days. Moreover, the early blinded rats had a higher level of learning than the lately blinded adult rats and the same level of learning as that of the sighted adult rats.

scholarly journals A Clinical and Microbiological Evaluation of Helicobacter pylori in Recurrent Aphthous Stomatitis

2017 ◽  
Vol 18 (12) ◽  
pp. 1194-1197
Author(s):  
Kamala Rajendra ◽  
Sadananda M Purnachandra ◽  
Parthkumar C Patel ◽  
Jochima Cota ◽  
Venkat R Singh ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Clinical Examination ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Gastric Ulcers ◽  
Control Group ◽  
Group Iii ◽  
Group I ◽  
The Social ◽  
H Pylori

ABSTRACT Aim The aim of this study is to evaluate the association of Helicobacter pylori in recurrent aphthous stomatitis (RAS) with or without peptic ulcer. Materials and methods A total of 42 patients were selected for the present study from outpatient Department of Oral Medicine, and divided into control (group I) and test groups (groups II, III). A total number of 15 patients suffering from RAS based on history and clinical examination was selected as group II. A total number of 12 patients suffering concomitantly from RAS and duodenal ulcer based on history and clinical examination were selected as group III. A total number of 15 healthy subjects were selected as controls in group I. All selected subjects belonged to the age group of 16 to 45 years. Data were tabulated and statistically analyzed with Statistical Package for the Social Sciences (SPSS) statistical software version 19 of IBM, Chicago, Illinois, USA. Results Among all three groups, 54.8% was negative and 45.2% was positive for H. pylori. No significant relation was established between H. pylori and RAS. Conclusion In the present study, there was no association of H. pylori in patients with RAS and in patients with RAS along with gastric ulcers. Clinical significance This clinical study evaluated the relation of H. pylori in RAS patients. How to cite this article Rajendra K, Purnachandra SM, Patel PC, Cota J, Singh VR, Vatsal A. A Clinical and Microbiological Evaluation of Helicobacter pylori in Recurrent Aphthous Stomatitis. J Contemp Dent Pract 2017;18(12):1194-1197.

scholarly journals Protective Effect of Morus Nigra Leaf Extract on Diazinon-Induced Hepatotoxicity in Rats

2020 ◽  
Vol 9 (3) ◽  
pp. 175-181
Author(s):  
Hina Majid ◽  
Salman Shahid ◽  
Sadia Shakeel ◽  
Mariam Ashraf ◽  
Muhammad Yasoob Ali ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Hepatic Tissue ◽  
Medical Institute ◽  
Control Group ◽  
P Value ◽  
Central Vein ◽  
Group Iii ◽  
Morus Nigra ◽  
Group I ◽  
Group Ii

Background: Diazinon is a globally used pesticide. Morus nigra (Black Mulberry) possesses flavonoids and phenols, which act as antioxidants. The objective of this study was to determine the possible protective effects of Morus nigra leaf extract on Diazinon-induced hepatotoxicity in rats. Material and Method: It was an experimental study conducted in the Department of Anatomy, Postgraduate Medical Institute, Lahore. A total of 36 healthy male Wistar albino rats were divided into three groups with 12 rats in each group. Group I was the control group. Group II was treated with 60 mg/kg body weight (bw) Diazinon daily for 4 weeks through orogastric intubation. Group III was treated with Diazinon 60 mg/kg bw daily along with 350 mg/kg bw of Morus nigra extract daily for 4 weeks through orogastric intubation. Blood samples were collected through cardiac puncture, for estimation of alanine transaminase (ALT) and aspartate transaminase (AST) levels. Liver dissection was done, slides of the hepatic tissue were prepared and studied under light microscope. The histology of hepatocytes, portal lobule, portal vein and sinuosoids was observed. SPSS 20 was used for data analysis. One-way ANOVA followed by Tukey’s test was applied to establish difference among groups with P-value ≤0.05 considered as statistically significant. Results: Histology of Liver tissue in group I showed normal morphology while group II revealed hypertrophy and vacuolization of hepatocytes, congested central vein and sinusoids and presence of necrotic foci. These toxic effects were reversed by the co-administration of Diazinon with Morus nigra in group III which showed normal histology of the hepatic tissue. Similarly, Diazinon administration resulted in significant elevation of ALT and AST levels (P-value<0.05), while, Morus nigra resulted in a considerable decline in the levels of these enzymes (P-value <0.05). Conclusion: Morus nigra extract has hepatoprotective effects against liver toxicity induced by Diazinon.

scholarly journals Microhardness and Fracture Resistance of Radicular Dentin Treated with Different Concentrations of Calcium Hydroxide in Endodontic Regeneration Procedures

2021 ◽  
Vol 9 (D) ◽  
pp. 324-329
Author(s):  
Sara N. Hashem ◽  
Maha Adel Elhousiny
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Fracture Resistance ◽  
Control Group ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Endodontic Regeneration ◽  
And Control ◽  
Control Group Group

Purpose: to reveal the effect of different concentrations of prepared calcium hydroxide pastes (70%, 50%, and 30%) used in regenerative endodontic on microhardness and fracture resistance of radicular dentin. Material and methods: Different concentrations of calcium hydroxide (Ca(OH)2) were prepared with measured pH, then forty eight single rooted teeth were prepared and randomized into three groups according to Ca(OH)2 paste concentrations (12 samples each) and 12 samples were availed as control group. Group I: root canal contained 30% Ca(OH)2 paste. Group II: root canal contained 50% Ca(OH)2 paste. Group III: root canal contained 70% Ca(OH)2 paste. Samples were stored at 37 0C with 100% humidity for four weeks for subsequent microhardness and fracture resistance tests. Results: There was a statistically significant reduction of microhardness  and fracture resistance between test groups and control group (P≤ 0.05), group III showed a  significant reduction  in both microhardness and fracture resistance compared to group I. However, there was no significant difference in pH between different concentration of Ca(OH)2. Conclusion: Increasing concentration of Ca(OH)2 paste can negatively affect microhardness and fracture resistance of radicular dentin in revascularization procedure.

The Quantitative Ultrastructure of the Heart Muscle of Japanese Quail by Hypergravitation, Hypodynamy and Combination

1990 ◽  
Vol 48 (3) ◽  
pp. 188-189
Author(s):  
Anton Bózner ◽  
Mikuláš Gažo ◽  
Jozef Dostál
Keyword(s):  
Japanese Quail ◽  
Heart Muscle ◽  
Relative Size ◽  
Combination Group ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Space Flights ◽  
Group I ◽  
Quantitative Ultrastructure

It is anticipated that Japanese quail /Coturnix coturnix japonica/ will provide animal proteins in long term space flights. Consequently this species of birds is of research interest of international space program INTERCOSMOS. In the year 1987 we reported on an experiment /2/ in which the effect of chronic acceleration of 2 G hypergravitation, the hypodynamy and the simultaneous effect of chronic acceleration and the location in the centre of the turntable of the centrifuge on the protein fractions in skeletal muscles was studied. The ultrastructure of the heart muscle was now in this experiments examined as well.Japanese quail cockerels, aged 48 days were exposed to 2 G hypergravitation /group IV/ in a 6,4 m diameter centrifuge, to hypodynamy /group III/ and their combination /group V/, respectively for 6 days / Fig.1/. The hypodynamy in group III was achieved by suspending the birds in jackets without contact the floor. The group II was located in the centre ofthe turntable of the centrifuge. The control group I. was kept under normal conditions. The quantitative ultrastructure of myocard was evaluated by the methods of Weibel/3/ - this enables to determine the number, relative size and volume of mitochondria volume of single mitochondria, defficiency of mitochondrial cristae and volume of myofibrils.

Features of the cervix uteri in women of reproductive age with endometrial polyps and micropolyps

2016 ◽  
pp. 108-111
Author(s):  
T.F. Tatarchuk ◽  
◽  
D.G. German ◽  
Keyword(s):  
Reproductive Age ◽  
Cervix Uteri ◽  
Control Group ◽  
Women Of Reproductive Age ◽  
Endometrial Polyps ◽  
Group Iii ◽  
Aggressive Form ◽  
Group I ◽  
Group Ii ◽  
Control Group Group

The article presents the comparative analysis of the state of the cervix in women with endometrial polyps and micropolyps. Patients and methods. The study involved 130 patients aged 18-35 years: 70 patients with endometrial polyps (group I), 30 patients with micropolyps (group II) and 30 patients of the control group (group III). Results. According to the anamnesis of women in the I group were significantly more frequent diseases of the cervix, which corrected physical surgery methods, in particular cryodestruction. In group II, the representatives of these indicators were similar to healthy. Normal colposcopic picture met significantly less frequently in patients and I, and II group. The differences in the incidence of HPV high oncogenic risk in all groups were not statistically significant. Conclusion. Destructive methods used in the detection of any changes in the cervix are often overly aggressive, form scars and contributing to inflamaciones process. In the chain of events leading to the formation of PE, cervical pathology and its correction can take the basic place. Key words: endometrial polyp, micropolyps, chronic endometritis, uterine cervix, colposcopy.

Efficacy of Ovsynch and Ovsynch Plus Protocol for Improvement of Fertility in Postpartum Sahiwal Cows

2019 ◽  
Vol 14 (04) ◽  
Author(s):  
J. P. Lakher ◽  
M. K. Awasthi ◽  
J. R. Khan ◽  
M. R. Poyam
Keyword(s):  
Fixed Time ◽  
Conception Rate ◽  
Control Group ◽  
Group Iii ◽  
Treatment Groups ◽  
Group I ◽  
Early Postpartum ◽  
The Status ◽  
Sahiwal Cows ◽  
And Control

The present study was conducted to investigate the efficacy of Ovsynch and Ovsynch plus protocol in postpartum (day 60) Sahiwal cows (n=18). Animals were randomly divided into three equal groups, viz., Ovsynch group Ovsynch plus group and Control group. Animals of group I (n = 6) were treated with traditional Ovsynch protocol. The animals (n = 6) of group II were treated with Ovsynch plus protocol which consisted of an initial intramuscular injection of eCG (Folligon) @ 250 IU on day 60 postpartum followed 3 days later by GPG (Ovsynch) protocol. In group-III Control, no treatment was given to animals (n = 6). Treated animals were inseminated at a fixed time between 14 and 20 hrs after second GnRH injection, irrespective of estrus detection. Blood samples were collected from each animal on days 50 and 60 postpartum to determine the status of cyclicity in animals based on serum concentrations of progesterone (P4). A third blood sample was collected on the day of prostaglandin treatment to determine the response of first GnRH injection. Four animals each were cyclic, and two were acyclic in both treatment groups. Four animals each responded to first GnRH treatment in both treatment groups. Similarly, two animals each got conceived giving conception rate of 50% (2/4) in each treatment. In the control group, one out of 6 animals got conceived yielding 16.66 % conception rate (1/6) during the study period. It may be thus concluded that Ovsynch and Ovsynch plus protocol may be used during the early postpartum period to improve the reproductive efficiency in postpartum Sahiwal cows.

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