scholarly journals Plants: a unique model for research on high diluted substances

2021 ◽  
Vol 10 (36) ◽  
pp. 265-267
Author(s):  
Tatiana Vladimirovna Novasadyuk
Keyword(s):  
Placebo Effect ◽  
High Efficiency ◽  
Tomato Fruit ◽  
Test Group ◽  
The Body ◽  
Control Group ◽  
Leningrad Region ◽  
Tomato Fruits ◽  
Unique Model ◽  
Homeopathic Remedies

Introduction: High efficiency and low cost of homeopathic drugs, lack of side effects and accumulation of toxins in animal farming products made homeopathy one of the priority developments in veterinary medicine. However, opponents of homeopathy have intensified their activity in the recent years. The attacks of the opponents of homeopathy, with their unfounded claims that it is totally explained by the placebo effect, can largely be explained by complexity of understanding the mechanism of action of these remedies which does not fit into the established concepts the effect of drugs on the body. That is why further study of homeopathic phenomenon is especially important in these days. In order to disproof the opinion that homeopathic phenomenon is explained by placebo effect, we have been studying the effect homeopathic remedies on vegetable growth and ripening. This choice was based on the hope that the opponents of homeopathy would not be able to accuse plants of self-suggestion under the effect of potentiated remedies. There are many publications about application of homeopathic remedies on plants. For example, in this direction such researchers as Stephan Baumgartner, Carneiro SMTPG, Rossi F, Carvalho LM, Bonato CM, Betti L, Lazzarato L V. Majewsky, and other researchers worked. Methods: Our first experiments that we performed during two years demonstrated a significant improvement of growth and ripening variables when homeopathic remedies were added to fertilizing mixtures, as compared with conventional plant care. Tomatoes of Typhoon F1 and Titan breeds were sued to study the effect of homeopathic remedies on plant growth and ripening. The studies were performed in greenhouse conditions in summer 2009 and 2010, on fertile soils of an experimental farm in the Krasnoselskiy district of the Leningrad region. Every study group of a certain tomato breed contained 20 plants. When the young plants were planted in the soil they were watered with adding Coca 1000 СН remedy, and then in one month the upper part of the plant was sprayed with Echinacea 30 СН. The same amounts of similar plants of the same breeds treated according to conventional agricultural technology were used as a control group. Results: As a result earlier ripening was found in the Typhoon F1 tomato breed: it occurred by 19 days earlier: that is by 18.3% than in the control group. The Titan tomatoes group ripened by 14.3% faster than in the control one. Every plant of the Typhoon breed produced an average of 45 tomato fruits, while in the control group the average number amounted to 14 (i.e. there was an increase of 221.4% in the test group). An average of 78 tomato fruits were produced by the Titan breed plants, while in the control group this number was only 20 (increase by 290%). Mean weight of the Typhoon tomato fruit increased by 59.5 g from the control values, i.e. by 180.8%. Mean weight of the Titan tomato fruit increased by 128.5 i.e. by 208.9%. A notable difference was found by all observers in the taste of experimental and control vegetables. The experimental plants had significantly better taste characteristics and they were also more resistant to buck eye rot. Conclusion: In such a way, the studies performed confirm the existence of homeopathic phenomenon in live organisms in the absence of the placebo effect. It has been demonstrated that the use of homeopathic remedies is effective in improvement of agricultural productivity. Plants are unique model for research of ultrahigh dilutions of substances.

Research on the methods and means of action strength training in aerobics training

2021 ◽  
pp. 002072092110042
Author(s):  
Xiaona Yang ◽  
Yang Ji ◽  
Da Ke ◽  
Fang Li
Keyword(s):  
Strength Training ◽  
Team Member ◽  
High Efficiency ◽  
Colleges And Universities ◽  
The Body ◽  
Energy Output ◽  
Control Group ◽  
Experimental Sample ◽  
Training Method ◽  
Core Strength

Aerobics is a beautiful and rhythmic sport. In recent years, aerobics has developed rapidly, and has become one of the essential courses of physical education in Colleges and universities. But the existing aerobics courses in Colleges and universities are less involved in the training process of action strength. Lack of strength quality is a common shortcoming of Aerobics Athletes in Colleges and universities. Therefore, this paper puts forward the methods and means of action strength training in aerobics training. According to the characteristics of competitive aerobics, combined with the traditional training strategy of action strength, this paper formulates the method of action strength training suitable for College Aerobics athletes. In order to further verify the effectiveness of this method, this paper takes a university aerobics team as an experimental sample to carry out a comparative analysis of the effect of action strength training. Relevant studies have proved that core strength training has the following effects on aerobics players: 1. Helps the calisthenics team member stabilize the trunk, improve the body's control ability and balance ability. 2. It is conducive to completing difficult movements of calisthenics with high efficiency and low energy consumption. 3. Helps the aerobics team member to enhance the special strength. 4. It can effectively prevent sports injuries. 5. It can improve the direction change and displacement speed of the body. 6. It can improve the energy output of the core strength to the limbs and other muscle groups during movement, so that the movement can be completed more perfectly.According to the results of the experiment, the explosive force and endurance of the experimental group after 8 weeks of training have been significantly improved, and formed a more obvious difference with the control group. The aerobics training method developed in this paper can be divided into two stages: the initial stage and the middle stage, which can better meet the students with different physical qualities. At the end of this paper, a fast strength training method is introduced, and the characteristics of different training methods are analyzed.

scholarly journals The Effect of Oxymel Syrup on Some Cardiovascular Risk Factors in Overweight and Obese People: A Randomized Controlled Trial Study

2021 ◽  
Author(s):  
Marjan Mahdavi Roshan ◽  
Arsalan Salari ◽  
Sogol Emaminejad ◽  
Shirin Parvinroo ◽  
Asieh Ashouri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Controlled Trial ◽  
Test Group ◽  
The Body ◽  
Risk Indicators ◽  
Blood Cholesterol ◽  
Control Group ◽  
Obese People

High blood pressure, diabetes, hyperlipidemia and obesity are risk factors for cardiovascular diseases. With regard to the significant role of a healthy diet in the prevention and even treatment of diseases together with the high cost and side effects of drugs, finding foods effective in the treatment of metabolic disorders has been widely considered. This study aimed to evaluate the effect of oxymel – an Iranian traditional syrup with vinegar base – on cardiovascular risk indicators in obese and overweight people. Candidates were selected based on a set of inclusion criteria and were divided into two groups of control and test. The control group received 250 cc of water, while the test group received 250 cc water containing 30 cc of the oxymel for 30 days. Anthropometric and biochemical indicators were measured at the beginning and end of the study. The results showed that there were no significant changes in the body mass index, waist circumference, hip circumference, waist to hip ratio, HDL, LDL, Triglycerides, systolic and diastolic blood pressure, and blood glucose level. However, weight (P = 0.053) and cholesterol (P = 0.083) decreased relatively significantly in the test group compared to the control group. This study shows that consumption of oxymel has positive cardiovascular effects such as lowering the blood cholesterol level and can contribute to weight loss; however, studies with a larger sample size are recommended.

Hematological profile of children with severe acute malnutrition: a tertiary care centre experience

2017 ◽  
Vol 4 (5) ◽  
pp. 1577 ◽  
Author(s):  
Arun Kumar Arya ◽  
Pramod Kumar ◽  
Tanu Midha ◽  
Mahendra Singh
Keyword(s):  
Severe Acute Malnutrition ◽  
Tertiary Care ◽  
Test Group ◽  
Mean Value ◽  
The Body ◽  
Acute Malnutrition ◽  
Control Group ◽  
Red Cell ◽  
Hematological Profile ◽  
Red Cell Indices

Background: Severe acute malnutrition (SAM) is associated with various pathophysiological changes in the body including hematological system. This study was done to understand the hematological profile of severely malnourished children.Methods: This case control study was conducted in the Department of pediatrics, G.S.V.M. Medical College, Kanpur from January 2014 to December 2015. 200 children, aged 6 months- 5years admitted to our hospital with SAM were enrolled as cases. 200 children with normal nutritional status without haematological or infectious conditions attending routine clinic were selected as controls. The hematological parameters were analyzed using an automated blood Analyzer.Results: 95% of the children with SAM had anemia, out of which 52% were severely anemic and 28% were moderately anemic. Mean value for hemoglobin was lower in test group (7.17±2.265gm/dl) as compared to control group (9.22±3.362gm/dl). Children with SAM had statistically significant lower mean values for red cell indices like RBC counts, MCV, MCH and MCHC compared to controls. The mean value of WBC in SAM children was 12.1±11.5×103, while it was 6.2± 7.8×103 in controls. The cases had higher mean value for neutrophils and lower mean value for lymphocytes.Conclusions: Children with SAM had lower mean hemoglobin, hematocrit and red cell indices and higher mean value of total leukocyte and platelet counts. This study recommends that more frequent studies should be done to describe the trend of hematopoietic changes in children with SAM to enhance anticipatory care and outcome of the affected children.

scholarly journals ERDOSTEINE: AN EFFECTIVE ANTIOXIDANT FOR PROTECTING COMPLETE FREUND’S ADJUVANT INDUCED ARTHRITIS IN RATS

2021 ◽  
pp. 71-75
Author(s):  
BANYLLA SYNMON ◽  
SANHATIDUTTA ROY ◽  
SUTAPA BISWAS MAJEE ◽  
MEGHNA PAUL ◽  
SANDIPAN DASGUPTA
Keyword(s):  
Body Weight ◽  
Test Group ◽  
The Body ◽  
Complete Freund’S Adjuvant ◽  
Control Group ◽  
Albino Rats ◽  
Standard Group ◽  
Freund’S Adjuvant ◽  
Complete Freund's Adjuvant ◽  
Freund's Adjuvant

Objective: The objective of this study was to evaluate the protective effect of Erdosteine on complete freund’s adjuvant (CFA) induced arthritic rats. Methods: Wistar Albino rats of 100–250 g were divided into five groups (n=6) and administered with 0.1 ml of CFA subcutaneously into the left hind paw except the negative control group. The standard group received methotrexate (MTX) 0.075 mg/kg body weight orally. Besides, the test groups received Erdosteine orally at a dose 10 mg/kg and 20 mg/kg bodyweight for 12 days. The changes in body weight, paw volume, hematological parameters, radiographical, and histological findings were the indicators to evaluate the efficacy of the test product. Discussion: Significant change in the body weight, paw volume, radiographical, hematological, and histological parameters were observed which supports the remarkable reduction of the arthritic development in the standard and test groups compared to the untreated group. However, the test group (Erdosteine) with the dose 20 mg/kg shows to be more potent than the test group (Erdosteine) with a dose 10 mg/kg and the standard group (MTX) to reduce the arthritic effect. Results: The test group with 20 mg/kg Erdosteine showed much better outcome than the standard group at significant (p<0.05). Therefore, Erdosteine acting as an anti-inflammatory and anti-oxidant is effective at a dose 20 mg/kg in treating the progression of rheumatoid arthritis in rats.

scholarly journals PHYSIOLOGICAL STATUS AND PRODUCTIVITY OF TURKEY-BROILERS WHEN USE FEED SUPPLEMENTS IN THEIR RATIONS

2017 ◽  
pp. 5-9
Author(s):  
Айметов ◽  
Ruslan Aymetov
Keyword(s):  
Test Group ◽  
Mineral Elements ◽  
The Body ◽  
Control Group ◽  
Physiological Status ◽  
Maximum Output ◽  
Mineral Supplement ◽  
Basic Diet ◽  
The Republic ◽  
Experimental Group

The mineral elements interact not only among themselves, but also with the organic components during complex metabolism process. Identifying the features of the feed nutrient substances relationship allows you to direct the body’s metabolism in the direction of their effectiveness and to obtain the maximum output from the animals. The experimental part of the work was carried out on poultry complex “Agrofirma Zalesnyy” of the Republic of Tatarstan from January to May 2016. The objects of research were female turkey-broilers of “Hybrid Converter” cross, mineral supplement “Tseostimul”, probiotic “Provagen” and symbiotic preparation of a new generation. With this aim, four groups of turkey were formed of 40 heads. The first group was a control one and received a basic diet, adopted by the poultry farm. The second group received the basic diet, added with mineral supplements with a dosage of 30 gramm per 1 kilogramm of feed. Turkeys of III-experimental group was added to the diet of probiotic preparation “Provagen” at a dose of 3 gramm per 1 kilogramm of feed. The turkeys of IV-test group received in addition to the basic diet a symbiotic drug rate of 20 gramm per 1 kilogramm of feed. The main diet was consisted of complete feed. Duration of the experiment was 112 days. By the end of the experiment the body weight of experimental groups exceeded the similar index: in the control group to 1082 gramm (р ≥0,001), in the first test group to 781 gramm (р ≥0,001), in the second test group to 1339 gramm (р ≥0,001), in the third group with addition of symbiotic drugs or to 12.3%, 8.9% and 15.3% respectively. The numbers of leukocytes was decreased from 34.2 109/L to 33.3 109/L in I experimental group, to 33.2 109/L in II and to 34.4 109/L in IV experimental group. The mass of internal organs was significantly higher in females of experimental groups. Thus, the weight of the liver of experimental groups was greater to 12.3%, 8.9% and 15.3%, compared with the control group.

scholarly journals Prebiotic Calf Supplement

2020 ◽  
Author(s):  
Н.И. Маслова ◽  
О.Б. Филиппова ◽  
А.И. Фролов ◽  
А.Н. Бетин
Keyword(s):  
Gastrointestinal Tract ◽  
Intestinal Parasites ◽  
Curcuma Longa ◽  
Test Group ◽  
Live Weight ◽  
The Body ◽  
Control Group ◽  
Chelidonium Majus ◽  
Significant Difference ◽  
Duration Of Disease

Эффективность применения кормовых пребиотических добавок в рационах телят возрастает в ранний (молочный) период их выращивания, когда происходит изменение трофических процессов, способов переработки пластических веществ, синхронизация биологических ритмов роста, развитие органов и систем организма, повышение чувствительности клеток к стимулирующим и тормозящим воздействиям. Цель работы заключалась в испытании кормовой пребиотической добавки, разработанной для профилактики и лечения диареи телят в молочный период выращивания. Опытная группа телят в период с 3- до 60-суточного возраста получала пребиотическую добавку в виде болюсов следующего состава (г): чистотел большой – 3,5; ромашка лекарственная – 3,5; куркума длинная – 0,6; аскорбиновая кислота – 1,2; фруктоза – 1,2; энтеросорбент – 2,0; сахар – 3,0; зерновая мука – 1,0. Суточная доза добавки, в зависимости от возраста и живой массы, составляла 12–16 г. В качестве энтеросорбента использовался глауконит Бондарского месторождения. В научно-производственном опыте установлено, что уже через два месяца экспериментального кормления отмечено статистически значимое различие в живой массе между группами, которое составило 2,1 кг в пользу опытных животных. Макроскопический анализ кала животных обеих групп показал, что консистенция, цвет и запах практически были одинаковыми, pH – слабокислая (5,23–5,22), примеси (кишечные паразиты и др.) отсутствовали, из чего следует, что секреторная и всасывающая функция желудочно-кишечного тракта у телят были нормальными. В контрольной группе у двух телят в течение первой недели после рождения были зафиксированы признаки нарушения функции желудочно-кишечного тракта (ЖКТ), которое сопровождалось диареей. Продолжительность болезни каждого телёнка составляла в среднем 4 суток. В целом, скармливание фитопребиотика в течение первых месяцев жизни телят оказало лечебное действие на простую диарею, обеспечило нормальное функционирование микробиоты кишечника, стимулировало увеличение среднесуточных приростов живой массы на 5%. The effectiveness of the use of prebiotic food supplements in diets of calves increases in the early (dairy) period of their growing when there is a change in trophic processes, methods of processing plastic substances, synchronization of biological growth rhythms, the development of organs and systems of the body, increasing the sensitivity of cells to stimulating and inhibitory effects. The purpose of the work was to test a food prebiotic supplement developed for the prevention and treatment of calf diarrhea during the dairy period of growing. Test group of calves from 3 to 60 days old received a prebiotic supplement in the form of boluses of the following composition (g): Chelidonium majus – 3.5; Matricaria chamomilla – 3.5; Curcuma longa – 0.6; ascorbic acid – 1.2; fructose – 1.2; enterosorbent – 2.0; sugar – 3.0; grain flour – 1.0. The daily dose of the supplement depending on age and live weight was 12–16 g. Glauconite of the Bondarsky deposit was used as an enterosorbent. In the research and production experiment it was found that after two months of experimental feeding a statistically significant difference in live weight between the groups was noted which amounted to 2.1 kg in favor of the experimental animals. Macroscopic analysis of feces in animals of both groups showed that the consistency, color and smell were almost the same, pH was slightly acidic (5.23–5.22), impurities (intestinal parasites, etc.) were absent which implies that the secretory and absorbing function the gastrointestinal tract in calves was normal. In the control group two calves during the first week after birth showed signs of a derangement of the function of the gastrointestinal tract (GIT) which was accompanied by diarrhea. The duration of disease of each calf averaged 4 days. In general feeding a phytoprebiotic during the first months of life of calves had a therapeutic effect on simple diarrhea, ensured the normal functioning of the intestinal microbiota and stimulated an increase in daily live weight gain by 5%.

scholarly journals CORRECTION OF HYPODINAMY AS A FACTOR OF THE RISK OF OBESITY DEVELOPMENT IN FIRE-RESCUERS

2018 ◽  
Vol 25 (3) ◽  
pp. 40-45
Author(s):  
E. V. BURDYUKOVA ◽  
A. N. ARKHANGELSKAYA ◽  
S. N. ALEKSEENKO ◽  
I. A. YAKIREVICH ◽  
E. A. DMITRIEVA ◽  
...  
Keyword(s):  
High Efficiency ◽  
Statistical Processing ◽  
Main Group ◽  
The Body ◽  
Control Group ◽  
Test Results ◽  
Food Label ◽  
Development Indicators ◽  
History Of ◽  
In Fire

Aim. To evaluate the effectiveness of the developed special sports complex in the prevention of hypodynamia and obesity among firefighters-rescuers.Materials and methods. A survey of 490 men with no history of chronic infectious and non-infectious diseases aged 20-59 was conducted. 328 people were the main group, 162 people were the control group. The baseline data included anthropometric development indicators, bioimpedance test results, the extraction of biochemical blood test results; the body mass index (BMI) and the ratio of waist and hip circumference were determined. A questionnaire was conducted to identify hypodynamia (according to the IPAQ questionnaire) and the nutrition structure (according to the questionnaire on the food label literacy questionnaire, past). Both questionnaires were adapted to the Russian Federation. Statistica for Windows 8.0 was used for statistical processing. We used a comparison of the means of the Student method. To compare the values expressed in percent, the method of inverse trigonometric Fisher transformations was used.Results. We have developed and proposed for firefighters-rescuers, included in the main group, special sports complexes, which were used for 6 months. These complexes represent additional physical training by the developed method. There are two of them: one with an emphasis on the prevention and rehabilitation of people with osteochondrosis of the lumbar spine, and the other for cervical and thoracic localization, including with a syndrome of shoulder-scapular periarthritis.Classes were held 3 times a week, the duration of 1 session was 45-50 minutes. The choice of the complex was carried out at the request of firefighters-rescuers. The first complex was selected by 52 people. Based on the results of the study, against the background of the use of sports complexes, there was a 2-fold decrease in the incidence of obesity. Such a high efficiency is due to the fact that obesity of the I degree prevailed among the firefighters-rescuers. In addition, the frequency of occurrence of dyslipidemia, hyperglycemia, and hypodynamia decreased.Conclusion. The use of this sports complex can reduce the risk factors for development of disability among rescue firefighters by preventing hypodynamia and reducing the incidence of hyperglycemia and dyslipidemia, as factors in the development of obesity.

scholarly journals Effect of TNF-α concentration on selected clinical parameters of swine after burns

2018 ◽  
Vol 62 (3) ◽  
pp. 335-340
Author(s):  
Roman Aleksiewicz ◽  
Krzysztof Lutnicki ◽  
Marta Likus ◽  
Łukasz Gątkiewicz
Keyword(s):  
Body Temperature ◽  
Serum Concentration ◽  
Respiration Rate ◽  
Pulse Rate ◽  
Test Group ◽  
The Body ◽  
Control Group ◽  
Burn Victims ◽  
Tnf Α ◽  
Highly Correlated

AbstractIntroductionThe study aimed to observe TNF-α serum concentration as well as changes in respiration rate, body temperature, and pulse rate in burn victims during 84 h post burn.Material and MethodsA total of 30 healthy pigs were divided into two groups: A, the test group and N, the control group. The experimental group suffered burns to 30% of the body surface, and after infliction of the burns both groups were closely monitored.ResultsThe biggest increase in TNF-α serum concentration in the test subjects occurred around the 6th h of the study, and the second biggest increase took place between 12th and 36th h. In the 36th h, TNF-α was 2.5 times more concentrated in serum in the test group than in the control group. In the test group, the biggest increase in respiration rate occurred up to the 6th h post burn, on average up to 29/min. In the 12th h post burn, the mean pulse rate in the test group was 133/min and dropped to the lowest value in the 72nd h of the experiment. A gradual increase in body temperature up to 41.72°C was observed up to the 30th h post burn and decreased to a significant value of 40.74°C by the 84th h of the study.ConclusionIn a period of a pronounced rise in TNF-α serum concentration, this parameter, pulse rate, and respiration rate are highly correlated and are also influenced by multiple inflammation forming factors.

scholarly journals Reduction Efficacy in Aerosol Production using 0.2% Chlorhexidine Gluconate Mouthwash in Dental Waterlines: A Clinicomicrobiological Study

2016 ◽  
Vol 7 (1) ◽  
pp. 1-5
Author(s):  
Suresh K Kasagani ◽  
Aditya G Rao ◽  
Kafeel Ahmed ◽  
Ghousia Fatima ◽  
Roopali Tapashetti
Keyword(s):  
Test Group ◽  
Chlorhexidine Gluconate ◽  
The Body ◽  
Blood Agar ◽  
Control Group ◽  
Team Members ◽  
Dental Chair ◽  
Airborne Contamination ◽  
Number Of Microorganisms ◽  
And Control

ABSTRACT Introduction Aerosol is a suspension of solid or liquid particles containing bacteria or viruses, suspended for at least a few seconds in a gas. The aerosol generated by an ultrasonic scaler contains microorganisms that can penetrate into the body through the respiratory system of dental surgeons and patients. The oral cavity harbors numerous bacteria and viruses from the respiratory tract, dental plaque, and oral fluids. Any dental procedure that has a potential to aerosolize saliva will cause airborne contamination with organisms. Aim To evaluate and compare the reduction efficacy in the levels of aerosol production at 1 foot, 5 feet, and 10 feet distance using 0.2% chlorhexidine gluconate mouthwash in dental waterlines. Materials and methods This single-center, randomized, two-group parallel design study was conducted over a period of 20 days. Twenty patients with chronic periodontitis were randomly divided into two groups: Test group and control group. Both the group samples were subjected to ultrasonic scaling. In the test group, 0.2% chlorhexidine gluconate mouthwash was added in the water dispenser bottle, whereas in the control group, distilled water was used. Blood agar plates were kept at distances of 1 foot, 5 feet, and 10 feet away from the headrest of the dental chair. Blood agar plates were incubated at 37°C for 48 hours, and the total number of colony-forming units (CFUs) was counted and statistically analyzed. Results The results of this study revealed that the experimental group showed higher reduction efficacy for aerosol production at 1 foot, 5 feet, and 10 feet distance from the center of the headrest of the dental chair compared with the control group. The results of this study also revealed that the number of CFUs was statistically significant only at 1 foot distance (p = 0.009) from the center of the headrest of the dental chair and not at 5 feet (p = 0.122) and 10 feet (p = 0.507) distances for both the groups. Conclusion This present study shows that the patient's chest area at a distance of 1 foot from the center of the headrest of dental chair receives a greater number of microorganisms than that at distances of 5 feet and 10 feet from the headrest of the dental chair. This validates the use of chlorhexidine in the form of an irrigant in dental waterlines as an additional barrier to cross-contamination, minimizing the risk to team members and the patient. How to cite this article Kasagani SK, Rao AG, Ahmed K, Fatima G, Tapashetti R. Reduction Efficacy in Aerosol Production using 0.2% Chlorhexidine Gluconate Mouthwash in Dental Waterlines: A Clinicomicrobiological Study. J Health Sci Res 2016;7(1):1-5.

scholarly journals UJI AKTIVITAS ANTIPIRETIK EKSTRAK DAUN SISIK NAGA(Pyrrosia piloselloides (L.) M.G. Price) TERHADAP TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIINDUKSI PEPTON 5%

2018 ◽  
Vol 15 (01) ◽  
pp. 22
Author(s):  
Ratna Widyasari ◽  
Dina Yuspitasari ◽  
Fadli Fadli ◽  
Athiah Masykuroh ◽  
Winda Tahuhiddah
Keyword(s):  
Body Temperature ◽  
Rattus Norvegicus ◽  
Test Group ◽  
Negative Control ◽  
The Body ◽  
Control Group ◽  
Antipyretic Activity ◽  
White Rats ◽  
Infra Red ◽  
Pyrrosia Piloselloides

INTISARI  Demam adalah keadaan ketika suhu tubuh meningkat melebihi suhu tubuh normal. Demam terjadi karena pelepasan  pirogen  dari dalam leukosit yang sebelumnya telah terangsang oleh pirogen  eksogen yang dapat berasal dari mikroorganisme atau merupakan suatu hasil reaksi imunologik yang tidak berdasarkan suatu infeksi. Sementara itu, banyak  negara telah mengembangkan pengobatan menggunakan herbal. Salah satu usaha yang dilakukan adalah dengan penggunaan obat tradisional. Penelitian ini bertujuan untuk membuktikan bahwa daun Sisik Naga (Pyrrosia piloselloides  (L.) M.G Price) dengan konsentrasi 0,062%, 0,125% dan 0,25% memiliki aktivitas antipiretik dengan menggunakan penginduksi demam  Pepton  5%. Penelitian ini merupakan penelitian eksperimental dengan Rancang Acak Lengkap (RAL). Pengukuran suhu rektal tikus menggunakan termometer  infra red. Hewan uji dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (suspensi Na-CMC 1%), kelompok kontrol positif (suspensi parasetamol) dan kelompok uji yaitu pemberian ekstrak daun sisik naga 0,062%, 0,125% dan 0,25%. Data yang diperoleh dianalisis dengan  menggunakan uji anova dan uji LSD (Least Significant Different). Hasil dari penelitian ini bahwa ekstrak daun sisik naga (Pyrrosia piloselloides  (L.) M.G Price) konsentrasi 0,25% mempunyai aktivitas antipiretik pada tikus putih (Rattus norvegicus) jantan galur wistar. Kata kunci: Antipiretik, Daun Sisik Naga (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%   ABSTRACT  A fever is a condition when the body temperature rises beyond the normal body temperature. Fever occurs due to the release of pyrogytes from within leukocytes that have previously been stimulated by exogenous pyrogens that may originate from microorganisms or are a result of immunologic reactions that are not based on an infection. Meanwhile, many countries have developed treatments using herbs. One of the efforts done is with the use of traditional medicine. This study aims to prove that the leaves of the Dragon Scales (Pyrrosia piloselloides (L.) M.G Price) with concentrations of 0.062%, 0.125% and 0.25% have antipyretic activity using Pepton fever induction 5%. This research is an experimental research with Completely Random Design (RAL). Rectal temperature measurements of mice using infra red thermometer. Test animals were divided into 5 groups: negative control group (1% Na-CMC suspension), positive control group (paracetamol suspension) and the test group were 0.062%, 0.125% and 0.25%. The data obtained were analyzed using anova test and LSD (Least Significant Different) test. The results of this study showed that the extract of leaf scales (Pyrrosia piloselloides (L.) M.G Price) concentrations of 0.25% had antipyretic activity in white rats (Rattus norvegicus) male wistar strain. Keywords: Antipyretics, Leaf Scales Dragon (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%

Sign in / Sign up

Export Citation Format

Share Document