DISTRIBUTION OF MYCOPLASMA SPP. AND UREAPLASMA SPP. AMONG PREGNANT WOMEN

The purpose of the present study is to determine the prevalence of genital mycoplasmas (M. genitalium, M. hominis, U. parvum, U. urealyticum) in pregnant women by molecular biological methods. Material/Methods: A prospective epidemiological study of 107 pregnant women hospitalized in the Clinic of Obstetrics and Gynecology, University Hospital-Pleven, Bulgaria, was conducted. Vaginal secretion samples were taken from all 107 pregnant women. A Polymerase chain reaction (PCR) assay was used to detect the genomic DNA of the bacteria in pregnant women. Results: The highest is the relative share of women in the age group from 20 to 35 years - 66 (64.68%), followed by women under 20 years - 27 (25.23%) and women over 35 years - 14 (13.08%). Detection of bacterial DNA was found in 85 (79.44%) of the cases, with present Ureaplasma spp. Colonization in 42 women (39.25%). Although no statistical dependence was found on open bacteria and age groups (p-value = 0.4688), it is noteworthy that the prevalence of Mycoplasma spp. and Ureaplasma spp. as a whole in the age group from 20 to 35 years, which has the highest birth rate, is more than twice higher than the group of up to 20 years and more than five times higher compared to the group over 35 years. Conclusions: Studies on the incidence of Mycoplasma spp. and Ureaplasma spp. in pregnant women is important for controlling the pregnancy, predicting the risk of developing maternal-fetal infection and discussing the options for timely treatment.

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Trends of Stomach Cancer in Central Serbia

Medicina ◽

10.3390/medicina57070665 ◽

2021 ◽

Vol 57 (7) ◽

pp. 665

Author(s):

Miodrag M. Stojanovic ◽

Natasa K. Rancic ◽

Marija R. Andjelkovic Apostolovic ◽

Aleksandra M. Ignjatovic ◽

Mirko V. Ilic

Keyword(s):

Stomach Cancer ◽

Preventive Measures ◽

Age Groups ◽

Optimal Number ◽

P Value ◽

Age Group ◽

Joinpoint Regression ◽

Mortality Trends ◽

Incidence Trend ◽

Incidence And Mortality

Somach cancer is the third most common cause of cancer-related deaths worldwide. The objective of the paper was to analyze the incidence and mortality trends of stomach cancer in Central Serbia in the period between 1999–2017. Materials and Methods: trends and annual percentage change (APC) of the incidence and mortality rate with corresponding 95% confidence intervals (CI) were calculated by joinpoint regression analyses. The optimal number of Joinpoints was identified using the Monte Carlo permutation method. The trend was considered to be significantly increasing (positive change) or decreasing (negative change) when the p-value was below 0.05 (p < 0.05). Results: the total number of new cases was 16,914 (10,873 males and 6041 females) and the total number of mortality cases was 14,790 (9348 in and 5442 in females). Almost one third (30.8%) of new cases were registered in the 60–69-year age group, and new cases were significantly more frequent in males than in females (30.8% vs. 29.02%, p < 0.001). Joinpoint regression analysis showed a significant decrease of incidence trend in females during the 2000–2015 period with APC of −2.13% (95% CI: −3.8 to −0.5, p < 0.001). An insignificant decrease in incidence trend was in males with APC of −0.72% (95% CI: −2.3 to 0.9, p = 0.30). According to the joinpoint analysis, a significant decrease of mortality trends both in males during 2000–2015 with APC of −2.21% (95% CI: −1.6 to −7.5, p ≤ 0.001 and in females, during the same period, with APC of −1.75% (95% CI: −2.9 to −0.6, p < 0.001) was registered. From 2015 to 2017, a significant increase of mortality was registered with APC of 44.5% (95% CI: from 24.2 to −68.1, p ≤ 0.001) in females and in males with APC of 53.15% (95% CI: 13.5 to −106.6, p ≤ 0.001). Conclusion: a significant decrease of stomach cancer incidence trend in females and insignificant decrease of incidence trend in males were determined in Central Serbia. Based on presented results, the mortality trend decreased significantly both in males and in females during 2000–2015, and from 2015 to 2017 we recorded a significant increase in mortality in both sexes. We found significantly more new cases in women than in men in the age group of 40–49, and the mortality of stomach cancer was significantly more frequent among females compared to males in the age groups 30–39, as well as in the 50–59 age group. There is a need for improving recording and registration of new cases of stomach cancer, especially in females. Urgent primary and secondary preventive measures are needed—introducing stomach cancer screening and early detection of premalignant changes. Urgent primary and secondary preventive measures are needed.

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Comparison of Human Thymus Gland between Young and Old Age

10.53350/pjmhs211561907 ◽

2021 ◽

Vol 15 (6) ◽

pp. 1907-1909

Author(s):

Faiza Mehboob ◽

Ponum Mirani ◽

M. Kamran Ameer ◽

Khurram Shabeer ◽

Muhammad Ali Qamar ◽

...

Keyword(s):

Connective Tissue ◽

Old Age ◽

Age Groups ◽

Young Age ◽

University Hospital ◽

P Value ◽

Old Patients ◽

Human Thymus ◽

Group I ◽

Significant Difference

Aim: Study was conducted to examine the different parameters of human thymus glands of young and old patients and compare the findings between both age groups. Study Design: Comparative/observational study Place and Study: Study was conducted at Anatomy department of Nishtar Medical University Hospital, Multan for duration of six months from 15th January 2020 to 15th July 2020. Methods: Total 54 specimens of human thymus of 54 patients were enrolled in this study. All specimens were divided in to two groups I and II, Group I contains 27 patients with ages <30 years and group II with 27 patients having ages 45 to 60 years. All specimens were fixed in 10% formalin solution and then processed for paraffin embedding. Compare the different parameters such as thickness of interlobular connective tissue and thymic capsule, length and number of Hassal’s corpuscles between both groups. Data was analyzed by SPSS 24.0. Results: In group I 12 (44.44%) patients were ages <15 years and 15 (55.56%) patients were ages >15 years. In group 13 (48.15%) and 14 (51.85%) patients were ages <50 years and >50 years. There was a significant difference observed between both groups regarding thickness of interlobular connective tissue and thymic capsule, quantity and length of Hassal’s corpuscles with p-value <0.05. Conclusion: It is to be concluded that patients with young age had significantly less thickness of thymic capsule and interlobular connective tissue with more in number and decreasing size of Hassal’s corpuscles as compared to old age patients. Keywords: Human Thymus Glands, Young Age, Old Age

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Healthy aging profile in octogenarians in Brazil

Revista Latino-Americana de Enfermagem ◽

10.1590/1518-8345.0694.2724 ◽

2016 ◽

Vol 24 (0) ◽

Cited By ~ 3

Author(s):

Ana Cristina Viana Campos ◽

Efigênia Ferreira e Ferreira ◽

Andréa Maria Duarte Vargas ◽

Lúcia Hisako Takase Gonçalves

Keyword(s):

Older Adults ◽

Decision Tree ◽

Healthy Aging ◽

Age Groups ◽

Population Based ◽

P Value ◽

Age Group ◽

Monthly Income ◽

Tree Model ◽

Socioeconomic Characteristics

ABSTRACT Objective: to identify the healthy aging profile in octogenarians in Brazil. Method: this population-based epidemiological study was conducted using household interviews of 335 octogenarians in a Brazilian municipality. The decision-tree model was used to assess the healthy aging profile in relation to the socioeconomic characteristics evaluated at baseline. All of the tests used a p-value < 0.05. Results: the majority of the 335 participating older adults were women (62.1%), were aged between 80 and 84 years (50.4%), were widowed (53.4%), were illiterate (59.1%), had a monthly income of less than one minimum wage (59.1%), were retired (85.7%), lived with their spouse (63.8%), did not have a caregiver (60.3%), had two or more children (82.7%), and had two or more grandchildren (78.8%). The results indicate three age groups with a healthier aging profile: older adults aged 80 to 84 years (55.6%), older adults aged 85 years and older who are married (64.9%), and older adults aged 85 and older who do not have a partner or a caregiver (54.2%). Conclusion: the healthy aging profile of octogenarians can be explained by age group, marital status, and the presence of a caregiver.

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Risk Factors Associated with Ischemic Heart Diseases in Different Age Groups Patients of Tertiary Care Hospitals of Peshawar

Journal of Gandhara Medical and Dental Science ◽

10.37762/jgmds.1-2.64 ◽

2015 ◽

Vol 1 (2) ◽

pp. 3-9

Author(s):

Riaz Gul ◽

Sumaira Naz

Keyword(s):

Risk Factors ◽

Heart Diseases ◽

Tertiary Care ◽

Age Groups ◽

Ischemic Heart ◽

P Value ◽

Age Group ◽

Ischemic Heart Diseases ◽

Sedentary Life ◽

Tertiary Care Hospitals

Objectives:To determine different risk factors associated with ischemic heart diseases in different age group patients of tertiary care hospitals of Peshawar.Methodology:A cross sectional study conducted on 350 patients of different age groups presented with ischemic heart diseases in tertiary care hospitals of Peshawar. Study was conducted for duration of 3 months from December 2013 to February 2014. Non probability convenient sampling technique was used. Sample size was calculated using standard sample size calculator. Semi structured questionnaire was used as data collection tool. Patient’s record and investigations were used as adding tools. Standard definition was made for ischemic heart disease. Different modifiable and non-modifiable factors were assessed and were analyzed using SPSS version 16.Results:This study contains 350 patients in which female patients were 133(38%) and male were 217(62%).The mean age was 57.23±11.36 years. The age of the patients ranges from 22 to 80 years. The frequencies of risk factors were stress (73.1%) followed by hypertension (65.7%), sedentary life style (59.4%), family history (57.1%), smoking (50.6%), over weight and obese (39.1%), below normal HDL (30.3%), high LDL (29.1%), hypertriglyceridemia (28%), hypercholesterolemia (23.7%). 64.3% patients were presenting with acute IHD and 35.7% were with chronic IHD. Stress, HTN, DM and sedentary life style were found to be significantly associated with male gender (p- value <0.05). Age was divided into two groups, <45 years and >45 years. Stress, HTN, DM and hypercholesterolemia had a significant association with >45 years of age group. (P-value <0.05).Conclusion:Stress, HTN, DM, sedentary life styles were the major risk factors. And they were found to be more in male gender and in equal to more than 45 years of age group.

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Prevalence of Hepatitis C Virus in the Population of Albania for the Period 2007-2010

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2014.094 ◽

2014 ◽

Vol 2 (3) ◽

pp. 525-528 ◽

Cited By ~ 1

Author(s):

Hysaj Vila Brunilda ◽

Shundi Lila ◽

Abazaj Erjona ◽

Bino Silva ◽

Rexha Tefta

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Age Groups ◽

Viral Disease ◽

Hcv Infection ◽

University Hospital ◽

P Value ◽

Hcv Rna ◽

Significant Difference ◽

Males And Females

BACKGROUND: Hepatitis C is a blood-borne, infectious, viral disease that is caused by a hepatotropic virus called Hepatitis C virus (HCV).AIM: The aim of this study is to determine the prevalence of active HCV infection (HCV–RNA) in the cases that were anti-HCV positive.MATERIAL AND METHODS: Plasma of 301 high-risk for HCV infection consecutive from University Hospital Centre “Mother Theresa” Tirana-Albania, during January 2007 to December 2010 was included in this study. To identify the presence of HCV RNA, the samples were examined by Cobas Amplicor HCV test (qualitative method).RESULTS: From 301 samples analyzed in total, 214 of them resulted positive for the presence of HCV-RNA's, corresponding to a prevalence of 71.1%, with 95% CI interval [65.8 - 75.9] for value of χ2 = 52.7 p value <0.0001. Divide by the sex 56% were males and 44% females, with statistically significant difference between them for value χ2 =4306 p value=0.0380. Among the age groups the highest prevalence was observed in the age groups > 25 years with a significant difference with other age groups for p value <0.001.CONCLUSION: Among tested samples, 71.1 % were confirmed to be positive for HCV –RNA infections. The prevalence of male was highest compared to female. For males and females infected the prevalence was highest in the age group of > 25 years.

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Monitoring HIV Epidemic in Pregnant Women: Are the Current Measures Enough?

Journal of Sexually Transmitted Diseases ◽

10.1155/2015/194831 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5

Author(s):

Purva Sarkate ◽

Supriya Paranjpe ◽

Nayana Ingole ◽

Preeti Mehta

Keyword(s):

Pregnant Women ◽

Age Groups ◽

Age Group ◽

Child Transmission ◽

Hiv Epidemic ◽

Opt Out ◽

Younger Age ◽

Heterogeneous Nature ◽

Program Data ◽

Local Levels

Introduction. Burden of HIV in pregnant women follows overall epidemic in India. Hence, it is imperative that prevalence calculations in this group be accurate. The present study was carried out to determine prevalence of HIV in pregnant women attending our hospital, to determine trend of HIV infection and to compare our results with reported prevalence. Methods. All pregnant women are routinely counselled for HIV testing using opt-out strategy. Year-wise positivity and trend were determined in these patients over a period of five years. The positivity in different age groups was determined. Results. 31,609 women were tested of which 279 (0.88%) were positive. Positivity showed a declining trend over study period and significant quadratic trend (biphasic, P<0.05) was observed. The positivity in older age group ≥35 years (1.64%) was significantly more than younger age groups (0.76% in 15–24-year and 0.94% in 25–34-year age group) (P=0.0052). Conclusion. A significant decline in HIV positivity was seen over the study period. Taking into account heterogeneous nature of HIV epidemic even within the same district, analysis at local levels especially using the prevention of parent to child transmission of HIV program data is critical for HIV programming and resource allocation.

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Population-based survey of HIV sero-status and vertical transmission among naive pregnant women in Sokoto, Nigeria

Asian Journal of Medical Sciences ◽

10.3126/ajms.v6i3.11530 ◽

2014 ◽

Vol 6 (3) ◽

pp. 49-57 ◽

Cited By ~ 2

Author(s):

Fiekumo Igbida Buseri ◽

Charity Ngozi Okonkwo

Keyword(s):

Antiretroviral Therapy ◽

Pregnant Women ◽

Vertical Transmission ◽

Statistical Significance ◽

Demographic Data ◽

Age Groups ◽

P Value ◽

Full Time ◽

Cross Sectional ◽

Significant Difference

Background: This study aims at investigating the seroprevalence of HIV infection among status naive pregnant women and probable vertical transmission in Sokoto, Nigeria.Materials and Methods: This cross-sectional study examined 13,026 apparently healthy pregnant women aged between 14 and 45 years and 312 mother-baby pairs in 4 different hospital settings in Sokoto State, North West, Nigeria between March, 2011 and February, 2013. The babies were aged between 8 and 16 months. HIV screening was performed using qualitative rapid tests and ELISA and HIV-DNA polymerase chain reaction (PCR) techniques. Measurement of CD4+ T-lymphocytes was carried out by the BD FACScount System. All seropositive pregnant women were immediately placed on triple antiretroviral therapy (ART) throughout the duration of the pregnancy and beyond.Results: An overall 2.4% prevalence of HIV-1 infection among the pregnant women and 20.5% incident of mother-to-child transmission were found. Of the seropositive pregnant women, 75.0% were full-time house wives, 13.8% and 11.2% were traders and civil servants respectively; of which, 70.2% were within the ages of 14 and 27 years (youthful predominance). Pearson’s χ2analysis did not show any statistically significant difference in the Mean values in the 4 health facilities (χ2 =2.084, df=3, P-value=0.555). Similarly, no significant difference in HIV seropositivity in the demographic data of the pregnant women were observed (P>0.05). Infection was recorded in all age groups but there was no statistical significance between age groups and infection (P = 0.833). Of the 64 seropositive babies, 62 (92.5%) contracted HIV from antiretroviral therapy non-adherence mothers (χ2 =271.457, df=1, P<0.01), OR=1506.6 (95%CI=285.5-7950.4). Conclusion: This study found high prevalence of vertical transmission due to ART non-adherence. Intervention initiatives should, therefore, focus seriously on ART non-adherence. DOI: http://dx.doi.org/10.3126/ajms.v6i3.11530Asian Journal of Medical Sciences Vol.6(3) 2015 49-57

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Retrospective Evaluation of Forensic Medicolegal Childhood Deaths Among Children Aged 0-6 Years

The Bulletin of Legal Medicine ◽

10.17986/blm.2019250194 ◽

2020 ◽

Vol 25 (2) ◽

pp. 65-71

Author(s):

Ali Yıldırım ◽

Erdoğan Polater ◽

Celal Bütün

Keyword(s):

Traffic Accident ◽

Age Groups ◽

Sudden Infant Death ◽

University Hospital ◽

Sudden Infant ◽

P Value ◽

Dead Body ◽

Retrospective Evaluation ◽

Manner Of Death ◽

Epidemiological Pattern

Objective:The aim of this study was to analyze the epidemiological pattern and characteristics of forensic cases resulting in death among children aged 0-6 years and to discuss the solution offers in order to prevent such events that may result in death in 0-6 years of childhood. Materials and Methods:73 cases of medicolegal childhood death among children aged 0-6 years whose post-mortem examinations, dead body examinations and/or autopsies were performed at the morgue of the Cumhuriyet University Hospital in a 8-year period between January 1, 2008 and December 31, 2016 were included in the study group and retrospectively analyzed. In all statistics, the SPSS v.20 statistical software was used, and a p value of <0.05 was accepted as statistically significant. Results:The study included 73 forensic cases resulted in death whose dead body examinations and autopsies were performed. Of the cases, 52.1% (n:38) were female and 47.9% (n:35) were male. When the age groups were compared, it was found that the highest mortality rate was in the 0-1 age group with 65.8%. When the manner of death was compared by age groups after autopsy and toxicology/histopathological examinations performed, it was found that the majority of deaths among children aged 0-1 years was due to sudden infant death syndrome with 35.4% (n:17), drowning in water was the most common cause of death between 2-3 years of age with 35% (n:7), followed by accidental deaths due to fall with 30% (n:6), and the deaths among children aged 4-6 years was due to traffic accident...

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Correlation Between Blood Glucose and Estradiol Levels in Women in Reproductive Age

Majalah Kedokteran Bandung ◽

10.15395/mkb.v52n3.2079 ◽

2020 ◽

Vol 52 (3) ◽

pp. 139-143

Author(s):

David Lionardi ◽

Chrismis Novalinda Ginting ◽

Linda Chiuman

Keyword(s):

Blood Sugar ◽

Blood Sugar Level ◽

Hormone Level ◽

Age Groups ◽

Reproductive Age ◽

P Value ◽

Age Group ◽

Type 2 Dm ◽

Two Age Groups

Type 2 Diabetes mellitus (Type 2 DM) is a metabolic disorder characterized by an increase in blood sugar caused by decreased insulin secretion by pancreatic beta cells and/or impaired insulin function (insulin resistance). This study aimed to determine the specific levels of estradiol hormone in reproductive age women with diabetes mellitus in different age groups. This was an analytical study in September at Royal Prima Hospital, North Sumatra, Indonesia. Twenty women participated in this study after informed consent and were divided into two age groups: 40–45 years old and 46–50 years old. Blood samples were collected after 10-12 hours of fasting to assess blood sugar and estradiol hormone levels. Data were then analyzed using the dependent t-test dependent and compared. No significant difference in blood sugar level was found between the two age groups (p-value=0.113, p-value> 0.05) that there were no significant differences in blood sugar levels between the two age groups. The estradiol hormone level in the age group 40-45 years was lower than in the age group 46–50 years, and the difference was significant (p-value =0.000, p-value<0.05). No significant correlation was seen between type 2 DM and estradiol hormone level in this study. In conclusion, age is not the main contributing factor for the increase and decrease in blood sugar level, and type 2 DM does not correlate with estradiol hormone.

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Food habits and Pregnancy outcomes

10.21203/rs.3.rs-132630/v1 ◽

2021 ◽

Author(s):

Devdatt Pitale

Keyword(s):

Socioeconomic Status ◽

Birth Weight ◽

Nutritional Status ◽

Pregnant Women ◽

Pregnancy Outcomes ◽

Food Habits ◽

P Value ◽

Age Group ◽

Maternal Nutritional Status ◽

Nicu Admission

Abstract Introduction: Nutrition during pregnancy plays an important role for an optimum outcome of pregnancy. Women may be malnourished even before they become pregnant and this may further adversely affect the pregnancy. Maternal undernutrition can lead to poor intrauterine growth and low weight of the baby at birth. Moreover, the leading causes for maternal deaths like hemorrhage and infection are related directly or indirectly to nutrition. Aim of the Study: To study the impact of existing food habits on pregnancy outcome in a south Indian population. Materials and Methods: This prospective study was conducted at a tertiary health care and research institute in India. From the antenatal clinic, 350 women who satisfied the following inclusion and exclusion criteria were admitted to the study. Results: The majority of pregnant women belonged to the age group of 21-25 yrs (47%) followed by the 26-30 yrs age group (40%).The number of teenage pregnancies was 30 (8%) whereas 5% of pregnant women belong the age group of 31-35 yrs.83% of the study population belonged to the low socioeconomic class. Majority of the babies (66%) had the birth weight in the range of 2.5-2.9 kgs. 29 % of babies had birth weight in the range of 3-3.5 kgs. There was a significant association (p value < 0.05) between the socioeconomic status of the mother, parity and her calorie intake. The present study found a statistically significant association between the maternal nutritional status, the birth weight of the baby and the need for NICU admission (p value < 0.05). Conclusion: Maternal food habits have an impact on the pregnancy outcome. Maternal food habits are influenced by many factors like socioeconomic status, parity, social food taboos and pregnancy itself. The pregnancy outcomes like birth weight, need for NICU admission and postnatal complications are influenced by maternal nutritional status.

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