scholarly journals Therapeutic potential of some Medicinal plants on wound healing

Author(s):  
Bhanumati Sarkar ◽  
◽  
Sandip Kumar Jana ◽  
Sk. Abul Kasem ◽  
Biplab Kumar Behera ◽  
...  

The present study deals with the study of the medicinal plants used by the old aged common people of the rural villages of Purba Medinipur district, West Bengal, India. The paper provide a brief account of four medicinal plant species, their extracts have immense potential for the treatment of wounds healing. Their natural agents induce healing and regeneration of host tissue by variable mechanisms. These plants extract exhibited also anti bacterial activity during wounds healing. This research aimed at promoting the conservation of these medicinal plants as well as wound healing purpose associated with them for cheap alternative healthcare resource.

2021 ◽  
Vol 11 (2) ◽  
pp. 72-75
Author(s):  
N Yasothkumar

Due to the presence of antibiotic or antiseptic nature’s chemicals, plants are remarkable for the treatment of wounds. Having this fact as research theme, the present study was carried out to document the therapeutic uses of medicinal plants used to heal wound in Karandamalai of Dindigul district in Tamil Nadu. The frequent fieldwork was conducted from October 2019 to January 2020 for this study. The scientific name, family name, local name (in Tamil), part(s) used, mode of preparation, and mode of administration of medicine were recorded. A total of 24 medicinal remedies prepared from 24 plants were recorded. Further research on the phytochemistry and pharmacology of these medicinal plants should be conducted. Keywords: Medicinal plants, Wound healing, Karandamalai, Dindigul district, Tamil Nadu.


Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2635
Author(s):  
Caroline Tyavambiza ◽  
Phumuzile Dube ◽  
Mediline Goboza ◽  
Samantha Meyer ◽  
Abram Madimabe Madiehe ◽  
...  

In Africa, medicinal plants have been traditionally used as a source of medicine for centuries. To date, African medicinal plants continue to play a significant role in the treatment of wounds. Chronic wounds are associated with severe healthcare and socio-economic burdens despite the use of conventional therapies. Emergence of novel wound healing strategies using medicinal plants in conjunction with nanotechnology has the potential to develop efficacious wound healing therapeutics with enhanced wound repair mechanisms. This review identified African medicinal plants and biogenic nanoparticles used to promote wound healing through various mechanisms including improved wound contraction and epithelialization as well as antibacterial, antioxidant and anti-inflammatory activities. To achieve this, electronic databases such as PubMed, Scifinder® and Google Scholar were used to search for medicinal plants used by the African populace that were scientifically evaluated for their wound healing activities in both in vitro and in vivo models from 2004 to 2021. Additionally, data on the wound healing mechanisms of biogenic nanoparticles synthesized using African medicinal plants is included herein. The continued scientific evaluation of wound healing African medicinal plants and the development of novel nanomaterials using these plants is imperative in a bid to alleviate the detrimental effects of chronic wounds.


2020 ◽  
Vol 6 (1) ◽  
pp. 65-74
Author(s):  
Md. Rajdoula Rafe ◽  
Rayhanus Salam ◽  
Syeda Naureen Ahmed ◽  
Zebunnesa Ahmed ◽  
Surid Mohammad Chowdhury

Traditional and folklore medicines have gained popularity throughout the world due to their safety. Herbal medicines with pharmacological activities and nutritional value are the most popular choice. Cultural and geographical factors of Bangladesh make it a vast source for herbal medicines. In addition, the cost-effectiveness of herbal medicines has also played an important role to make it a drug of choice among the developing countries like Bangladesh. People of Bangladesh have been using plants for centuries to treat different wounds caused by excision and incision. In this current review, we have gone through an extensive literature search to find out the four most commonly used medicinal plants for the treatment of wounds and their pharmacological activities in scientific researches. The featured plants of this review articles are, Calotropis gigantea, Cynodon dactylon, Acorus calamus and Justicia gendarussa. In traditional and herbal medicines, many plants are used without their scientific validation and we intend to perform a literature review in order to find out the potential scientific value of the featured plants. In addition, with pharmacological activities, their traditional formulation as a wound healing drug is also added to this article. This study will help validate the uses of these plants as traditional medicine and for researchers to find out potential therapeutic drugs according to their pharmacological studies.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Wubante Demilew ◽  
Getnet Mequanint Adinew ◽  
Seyfe Asrade

Background. Medicinal plants play indispensable roles to treat various ailments. Acanthus polystachyus is one of the medicinal plants used traditionally for treatment of wounds. However, there were no scientific reports documented so far on the wound healing activities of this plant. Thus, the present study provides a scientific evaluation for the wound healing potential of the crude extract of A. polystachyus leaves. Methods. The crude extraction was carried out using 80% methanol. The crude extract was prepared in 5% (w/w) and 10% (w/w) ointment and evaluated for wound healing activity using excision, infected, and incision wound models in Swiss albino mice. Results. Both 5%  and 10% (w/w) ointments significantly reduced period of epithelialization and increased wound contraction rate and tensile strength compared to the negative control group (P < 0.05). The wound healing activity of 10% (w/w) ointment treated group was greater than 5% (w/w) and nitrofurazone ointment treated groups in S. aureus infected wound model. Conclusion. These results demonstrate that the crude extract of A. polystachyus leaves possesses wound healing activities. This justifies the traditional claimed use of the plant for treating uninfected and infected wounds caused by S. aureus.


2019 ◽  
Vol 26 (13) ◽  
pp. 2389-2406 ◽  
Author(s):  
Haroon Khan ◽  
Mina Saeedi ◽  
Seyed Mohammad Nabavi ◽  
Mohammad S. Mubarak ◽  
Anupam Bishayee

Background: Cancer continues to be a global burden, despite the advancement of various technological and pharmaceutical improvements over the past two decades. Methods for treating cancer include surgery, radiotherapy and chemotherapy in addition to other specialized techniques. On the other hand, medicinal plants have been traditionally employed either as the complementary medicine or dietary agents in the treatment and management of cancer. Medicinal plants are a rich source of secondary metabolites with interesting biological and pharmacological activities. Among these metabolites, glycosides are naturally occurring substances and have outstanding therapeutic potential and clinical utility. Methods: Different medical research engines such as, GoogleScholar, PubMed, SpringerLink, ScienceDirect were used to collect related literature on the subject matter. In this regard, only peer-reviewed journals were considered. Results: Emerging results showed that numerous glycosides isolated from various plants possessed marked anticancer activity against a variety of cancer cell lines. Accordingly, the aim of the present review is to shed light on the anticancer effects of glycosides, analyze possible mechanisms of action, and highlight the role of these natural agents as complementary and alternative medicine in combating and managing cancer. Conclusion: The glycosides isolated from different plants demonstrated potent cytotoxic effects against various cancer cell lines in initial preclinical studies. The anticancer effect was mediated through multiple mechanisms; however further detailed studies are needed to understand the full potential of glycosides for clinical utility.


Author(s):  
Stephen EMMANUEL ◽  
Ademidun Adeola ADESIBIKAN ◽  
Oluwole Solomon OLADEJI

The applications of medicinal plant species for diverse therapeutic effects are well documented throughout the world. In recent times, the screening of higher plants for unique biologically active compounds, particularly those with pronounced therapeutic potency, has received the interest of the science community. A wound is a loss or break in the anatomic stability of active tissue. It not only poses a physical and mental threat to zillions of people but could cause the failure of multiple organs, amputation, and even death. Therefore, thousands of plants have been screened to obtain active metabolites or compounds that can accelerate the process of restoring the damaged tissue structure and inhibit the probability of infections. Due to the severity of wounds to the human body, it is essential to explore safe, economical, and environmentally friendly therapeutics from nature. This review aims to conduct a comprehensive search of medicinal herbs to uncover their therapeutic potential, identify gaping holes, and assess future research prospects that could lead to the discovery of novel pharmacophores. Thus, the review is tailored towards the appraisals of phytotherapeutic mechanism and wound healing efficacy of medicinal plants, which will help spur future research and improve our current knowledge leading to the unearthing of novel and potent pharmacophores with pronounced wound healing potentials. Several medicinal plants with scientifically proven wound-healing activities are reported and discussed alongside phytochemicals present their various extracts and isolates. The achievable wound-healing closure rate of each plant was also reported with a focus on what is responsible for the healing rate.


2018 ◽  
Vol 9 (2) ◽  
pp. 42-78
Author(s):  
Tarun Sharma ◽  
Bhargav Bhide ◽  
Rabinarayan Acharya

Plants are traditionally being used as a source of medicine by indigenous people of different ethnic groups inhabiting various terrains for the control of various ailments effecting both human and animals. Recently, focus on plant research has been increased, all over the world, due to the huge potential of medicinal plants used in various traditional systems. Wounds are the result of injuries to the skin that disrupt the soft tissue. Various plants have been used in treatment of wounds over the years in many tribal areas. Many ethno botanical survey reports and books have been published highlighting the use of plant as a whole or its various parts for the management of wounds. Recent research shows that some of these plants are established either experimental or clinical studies for their wound healing activities. Single hand information regarding these plants with their specific parts used for wound healing activity is lacking. Hence, the present study is an attempt to compile the leaf drugs reported for their wound healing activity from 85 research articles and 14 books related to ethno medicine and ethno botany. It is observed that ethno medicinal plants belonging to 100 families (Asteraceae-51, Fabaceae-38, Euphorbiaceae-34, Lamiaceae-19, Rubiaceae-17 etc.) are reported for their wound healing activity. Among them 202 plants reported for topical application, 11 for oral administration and 9 for both (oral and topical).  


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Akshay Sharma ◽  
Suryamani Khanna ◽  
Gaganjot Kaur ◽  
Inderbir Singh

Abstract Background Wound is an anatomical and functional disruption of the skin following an injury. In response to the injury, wound healing is a complex process of tissue repair or remodeling. Historically, plants and plant-based constituents have been extensively used for the treatment and management of different types of wounds. In the current times, different types of biopolymers are being researched for developing economical, sustainable, stable, and effective delivery system for the treatment of wounds. Main text The present review article attempts to enlist medicinal plants which have been reported to be effective in the treatment of wounds. Plant constituent-based wound dressings have also been discussed systematically including patented formulations reported by different inventors. Conclusion The compiled data aims to update the researchers/scientists which will be helpful in providing them a directional view in understanding the role and importance of plant-based components for the treatment and management of wounds.


2020 ◽  
Vol 26 ◽  
Author(s):  
Kondeti Ramudu Shanmugam ◽  
Bhasha Shanmugam ◽  
Gangigunta Venkatasubbaiah ◽  
Sahukari Ravi ◽  
Kesireddy Sathyavelu Reddy

Background : Diabetes is a major public health problem in the world. It affects each and every part of the human body and also leads to organ failure. Hence, great progress made in the field of herbal medicine and diabetic research. Objectives: Our review will focus on the effect of bioactive compounds of medicinal plants which are used to treat diabetes in India and other countries. Methods: Information regarding diabetes, oxidative stress, medicinal plants and bioactive compounds were collected from different search engines like Science direct, Springer, Wiley online library, Taylor and francis, Bentham Science, Pubmed and Google scholar. Data was analyzed and summarized in the review. Results and Conclusion: Anti-diabetic drugs that are in use have many side effects on vital organs like heart, liver, kidney and brain. There is an urgent need for alternative medicine to treat diabetes and their disorders. In India and other countries herbal medicine was used to treat diabetes. Many herbal plants have antidiabetic effects. The plants like ginger, phyllanthus, curcumin, aswagandha, aloe, hibiscus and curcuma showed significant anti-hyperglycemic activities in experimental models and humans. The bioactive compounds like Allicin, azadirachtin, cajanin, curcumin, querceitin, gingerol possesses anti-diabetic, antioxidant and other pharmacological properties. This review focuses on the role of bioactive compounds of medicinal plants in prevention and management of diabetes. Conclusion: Moreover, our review suggests that bioactive compounds have the potential therapeutic potential against diabetes. However, further in vitro and in vivo studies are needed to validate these findings.


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