scholarly journals Medicinal plants and their components for wound healing applications

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Akshay Sharma ◽  
Suryamani Khanna ◽  
Gaganjot Kaur ◽  
Inderbir Singh
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Tissue Repair ◽  
Review Article ◽  
Wound Dressings ◽  
Complex Process ◽  
Different Types ◽  
Plant Constituent ◽  
Effective Delivery ◽  
Treatment Of Wounds

Abstract Background Wound is an anatomical and functional disruption of the skin following an injury. In response to the injury, wound healing is a complex process of tissue repair or remodeling. Historically, plants and plant-based constituents have been extensively used for the treatment and management of different types of wounds. In the current times, different types of biopolymers are being researched for developing economical, sustainable, stable, and effective delivery system for the treatment of wounds. Main text The present review article attempts to enlist medicinal plants which have been reported to be effective in the treatment of wounds. Plant constituent-based wound dressings have also been discussed systematically including patented formulations reported by different inventors. Conclusion The compiled data aims to update the researchers/scientists which will be helpful in providing them a directional view in understanding the role and importance of plant-based components for the treatment and management of wounds.

scholarly journals Medicinal Plants Used to Heal Wound in Karandamalai of Dindigul District in Tamil Nadu, Southern India

2021 ◽  
Vol 11 (2) ◽  
pp. 72-75
Author(s):  
N Yasothkumar
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Tamil Nadu ◽  
Southern India ◽  
Mode Of Administration ◽  
Therapeutic Uses ◽  
Research Theme ◽  
Treatment Of Wounds ◽  
Scientific Name

Due to the presence of antibiotic or antiseptic nature’s chemicals, plants are remarkable for the treatment of wounds. Having this fact as research theme, the present study was carried out to document the therapeutic uses of medicinal plants used to heal wound in Karandamalai of Dindigul district in Tamil Nadu. The frequent fieldwork was conducted from October 2019 to January 2020 for this study. The scientific name, family name, local name (in Tamil), part(s) used, mode of preparation, and mode of administration of medicine were recorded. A total of 24 medicinal remedies prepared from 24 plants were recorded. Further research on the phytochemistry and pharmacology of these medicinal plants should be conducted. Keywords: Medicinal plants, Wound healing, Karandamalai, Dindigul district, Tamil Nadu.

scholarly journals Wound-healing activity of immobilized postbiotics from Bacillus subtilis exometabolites

2021 ◽  
Vol 40 ◽  
pp. 01002
Author(s):  
Dina Shokatayeva ◽  
Irina Savitskaya ◽  
Aida Kistaubayeva
Keyword(s):  
Wound Healing ◽  
Bacillus Subtilis ◽  
Healing Process ◽  
Antagonistic Activity ◽  
Healing Time ◽  
Wound Dressings ◽  
Laboratory Animals ◽  
Wound Healing Process ◽  
Antimicrobial Substances ◽  
Treatment Of Wounds

The biological activity of postbiotic from Bacillus subtilis exometabolites was determined due to protein content - 0.541±13.4 mg/ml, the level of proteases - 7.8±0.3 U/ml and the presence of antimicrobial substances. A biocomposite material was developed by co-aggregation of bacterial cellulose, chitosan and Bacillus exometabolites. Modified BC gel film possesses high antagonistic activity against causative agents of wound infections: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis. The use of the obtained material in treatment of wounds on laboratory animals reduces healing time by an average of 20%. The developed bioactive wound dressings is intended for local application in order to optimize the wound healing process.

scholarly journals Wound Healing Activities and Potential of Selected African Medicinal Plants and Their Synthesized Biogenic Nanoparticles

Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2635
Author(s):  
Caroline Tyavambiza ◽  
Phumuzile Dube ◽  
Mediline Goboza ◽  
Samantha Meyer ◽  
Abram Madimabe Madiehe ◽  
...  
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Wound Repair ◽  
Chronic Wounds ◽  
In Vivo Models ◽  
Repair Mechanisms ◽  
Treatment Of Wounds ◽  
Biogenic Nanoparticles

In Africa, medicinal plants have been traditionally used as a source of medicine for centuries. To date, African medicinal plants continue to play a significant role in the treatment of wounds. Chronic wounds are associated with severe healthcare and socio-economic burdens despite the use of conventional therapies. Emergence of novel wound healing strategies using medicinal plants in conjunction with nanotechnology has the potential to develop efficacious wound healing therapeutics with enhanced wound repair mechanisms. This review identified African medicinal plants and biogenic nanoparticles used to promote wound healing through various mechanisms including improved wound contraction and epithelialization as well as antibacterial, antioxidant and anti-inflammatory activities. To achieve this, electronic databases such as PubMed, Scifinder® and Google Scholar were used to search for medicinal plants used by the African populace that were scientifically evaluated for their wound healing activities in both in vitro and in vivo models from 2004 to 2021. Additionally, data on the wound healing mechanisms of biogenic nanoparticles synthesized using African medicinal plants is included herein. The continued scientific evaluation of wound healing African medicinal plants and the development of novel nanomaterials using these plants is imperative in a bid to alleviate the detrimental effects of chronic wounds.

scholarly journals Therapeutic potential of some Medicinal plants on wound healing

2016 ◽  
Vol 2 ◽  
pp. 1-4
Author(s):  
Bhanumati Sarkar ◽  
◽  
Sandip Kumar Jana ◽  
Sk. Abul Kasem ◽  
Biplab Kumar Behera ◽  
...  
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Healthcare Resource ◽  
Therapeutic Potential ◽  
Common People ◽  
Rural Villages ◽  
Natural Agents ◽  
Cheap Alternative ◽  
Treatment Of Wounds ◽  
Immense Potential

The present study deals with the study of the medicinal plants used by the old aged common people of the rural villages of Purba Medinipur district, West Bengal, India. The paper provide a brief account of four medicinal plant species, their extracts have immense potential for the treatment of wounds healing. Their natural agents induce healing and regeneration of host tissue by variable mechanisms. These plants extract exhibited also anti bacterial activity during wounds healing. This research aimed at promoting the conservation of these medicinal plants as well as wound healing purpose associated with them for cheap alternative healthcare resource.

Natural Inorganic Ingredients in Wound Healing

2020 ◽  
Vol 26 (6) ◽  
pp. 621-641 ◽  
Author(s):  
Fátima García-Villén ◽  
Iane M.S. Souza ◽  
Raquel de Melo Barbosa ◽  
Ana Borrego-Sánchez ◽  
Rita Sánchez-Espejo ◽  
...  
Keyword(s):  
Wound Healing ◽  
Clay Minerals ◽  
Chronic Wounds ◽  
Inorganic Materials ◽  
Wound Dressings ◽  
Mechanical Resistance ◽  
Efficient Treatment ◽  
Antimicrobial Effects ◽  
Chemical Release ◽  
Treatment Of Wounds

Background: One of the major clinical challenges is to achieve a rapid and efficient treatment of complex chronic wounds. Nowadays, most wound dressings currently available are unable to find a solution the challenges of resistance to bacterial infection, protein adsorption and increased levels of exudates. Natural inorganic ingredients (clay minerals, metal cations, zeolites, etc) could be the key to solve the problem satisfactorily. Some of these materials have shown biocompatibility and ability to enhance cell adhesion, proliferation and cellular differentiation and uptake. Besides, some natural inorganic ingredients effectively retain drugs, allowing the design of drug delivery matrices. Objective: possibilities of natural inorganic ingredients in wound healing treatments have been reviewed, the following sections have been included: 1. Introduction 2. Functions of Inorganic Ingredients in wound healing 2.1. Antimicrobial effects 2.2. Hemostatic effects 3. Clay minerals for wound healing 3.1. Clay minerals 3.2. Clay mineral semisolid formulations 3.3. Clay/polymer composites and nanocomposites 3.4. Clay minerals in wound dressings 4. Other inorganic materials for wound healing 4.1. Zeolites 4.2. Silica and other silicates 4.3. Other minerals 4.4. Transition metals 5. Conclusion Conclusion: inorganic ingredients possess useful features in the development of chronic wounds advanced treatments. They improve physical (mechanical resistance and water vapor transmission), chemical (release of drugs, hemostasis and/or adsorption of exudates and moisture) and biological (antimicrobial effects and improvement of healing) properties of wound dressings. In summary, inorganic ingredients have proved to be a promising and easily accessible products in the treatment of wounds and, more importantly, chronic wounds.

A Pharmacological Review of Four Widely Used Traditional Medicinal Plants for Wound Healing in Bangladesh

2020 ◽  
Vol 6 (1) ◽  
pp. 65-74
Author(s):  
Md. Rajdoula Rafe ◽  
Rayhanus Salam ◽  
Syeda Naureen Ahmed ◽  
Zebunnesa Ahmed ◽  
Surid Mohammad Chowdhury
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Cynodon Dactylon ◽  
Herbal Medicines ◽  
Acorus Calamus ◽  
Extensive Literature ◽  
Pharmacological Activities ◽  
Drug Of Choice ◽  
Therapeutic Drugs ◽  
Treatment Of Wounds

Traditional and folklore medicines have gained popularity throughout the world due to their safety. Herbal medicines with pharmacological activities and nutritional value are the most popular choice. Cultural and geographical factors of Bangladesh make it a vast source for herbal medicines. In addition, the cost-effectiveness of herbal medicines has also played an important role to make it a drug of choice among the developing countries like Bangladesh. People of Bangladesh have been using plants for centuries to treat different wounds caused by excision and incision. In this current review, we have gone through an extensive literature search to find out the four most commonly used medicinal plants for the treatment of wounds and their pharmacological activities in scientific researches. The featured plants of this review articles are, Calotropis gigantea, Cynodon dactylon, Acorus calamus and Justicia gendarussa. In traditional and herbal medicines, many plants are used without their scientific validation and we intend to perform a literature review in order to find out the potential scientific value of the featured plants. In addition, with pharmacological activities, their traditional formulation as a wound healing drug is also added to this article. This study will help validate the uses of these plants as traditional medicine and for researchers to find out potential therapeutic drugs according to their pharmacological studies.

scholarly journals Evaluation of the Wound Healing Activity of the Crude Extract of Leaves of Acanthus polystachyus Delile (Acanthaceae)

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Wubante Demilew ◽  
Getnet Mequanint Adinew ◽  
Seyfe Asrade
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Crude Extract ◽  
Negative Control Group ◽  
Treated Group ◽  
Negative Control ◽  
Control Group ◽  
Wound Model ◽  
Treatment Of Wounds ◽  
Wound Healing Activity

Background. Medicinal plants play indispensable roles to treat various ailments. Acanthus polystachyus is one of the medicinal plants used traditionally for treatment of wounds. However, there were no scientific reports documented so far on the wound healing activities of this plant. Thus, the present study provides a scientific evaluation for the wound healing potential of the crude extract of A. polystachyus leaves. Methods. The crude extraction was carried out using 80% methanol. The crude extract was prepared in 5% (w/w) and 10% (w/w) ointment and evaluated for wound healing activity using excision, infected, and incision wound models in Swiss albino mice. Results. Both 5%  and 10% (w/w) ointments significantly reduced period of epithelialization and increased wound contraction rate and tensile strength compared to the negative control group (P < 0.05). The wound healing activity of 10% (w/w) ointment treated group was greater than 5% (w/w) and nitrofurazone ointment treated groups in S. aureus infected wound model. Conclusion. These results demonstrate that the crude extract of A. polystachyus leaves possesses wound healing activities. This justifies the traditional claimed use of the plant for treating uninfected and infected wounds caused by S. aureus.

scholarly journals REVIEW ARTICLE: GARLIC: NATURE’S PROTECTION AGAINST WOUNDS

2020 ◽  
Vol 21 (supplement 1) ◽  
Author(s):  
Gurjot Kaur ◽  
Reena Gupta
Keyword(s):  
Cardiovascular Disease ◽  
Wound Healing ◽  
Allium Sativum ◽  
Review Article ◽  
Full Thickness ◽  
Complex Process ◽  
Anti Cancer ◽  
Superficial Wound ◽  
Healing Of Wounds ◽  
Full Thickness Wound

Wounds can occur due to any injury, disease state or insect bite or abrasions. Wound healing is a complex process that includes many phases and involves a number of inflammatory mediators wound can be classified as acute and chronic. Other than this wound can also be classified on the basis of layer of skin that gets damaged: Superficial wound, Partial thickness wound and Full thickness wound. Garlic (Allium sativum) has been used as food and also used for the treatment of many diseases, for healing of wounds etc. Garlic is perennial liliaceous herb with a bulb having organosulphur compounds like Diallyl disulphide, diallyl sulphide, diallyl trisulphide and sulphur dioxide others are allin, allicin, etc. Garlic having major properties includes anti-cancer, against cardiovascular disease, antioxidant,anti-microbial, in wound healing etc

An Overview of the Most Important Medicinal Plants Native to Iran by Property of Burn Wound Healing: A Systematic Review

2017 ◽  
Vol 8 (02) ◽  
Author(s):  
Mehrdad Karimi ◽  
Mahnaz Mardani ◽  
Leila Mahmoodnia
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Cinnamic Acid ◽  
Healing Process ◽  
Review Article ◽  
The Body ◽  
Wound Healing Process ◽  
Burn Wound ◽  
Burn Wounds ◽  
Burn Wound Healing

Burn is an injury where the skin is destroyedby various factors such as heat, cold, electricity, etc.When skin injuryoccurs, pathogens can invade the body and burn wounds get infected shortly after the damage. The wound healing process is a process done by the coordination of tissues, cells and various factors. In the acute phase, inflammatory mechanism of burns has negative effects due to capillary leak. On the other hand, in the later stages of burn,inflammation is necessary for wound healing. Silver nitrate, silver sulfadiazine, and Mafenide acetate are also used for wound care. These compounds cause delayed wound healing and have cytotoxic effects. Iran is among the countries that have rich traditional medicine and herbal treatment of burn wounds in history. Therefore, in this review article, we tried to report the medicinal plants native to Iran which are effective for burn wounds. In this review article, by searching databases such as Scopus, Google Scholar, Spy DVD, mag Iran and… the articles were searched by searching keywords including burn wounds, herbs, extracts, essences and Iran. After finally searching, it was determined that medicinal plants below are the most important medicinal plants native to Iran that affect burn wounds. 11 Medicinal herbs 11 Abukhalsa plant, chamomile, oak, hungry for love, green tea, purslane, cinnamon, Hypericum, and Commiphora are the most important Medicinal Plants which are effective for burn wound healing in Iran. Alkanin, Naphthoquinone and Shikonin, tannins, pectin, alkaloids, saponins and tannins fixed, resin and vitamin C, flavonoids rutin, aucubin and catalpolCatechin, Epicatechin, EpicatechinGallate, Epigallocatechin and Epigallocatechin-gallate, oxalic acid, Cinnamic acid, caffeic acid , maleic acid, Citric acid, coumarin, flavonoids, alanine, tannins, alpha-linolenic acid, cinnamic acid, phenolic compounds such as eugenol, and safrolephellandrene, terpene compounds such as limonene and linalool, trans-cinnamaldehyde (MDA), tannins, coumarin, resin, Cinema-hydroxy phenyl propane compounds such as formaldehyde and mannitol, curcumin, terpenoids, steroids, Flavonoids, lignans are active compounds of plant bioactive substances that are effective on burn wound healing.

A review of Tunisian medicinal plants with anticancer activity

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Wissem Aidi Wannes ◽  
Moufida Saidani Tounsi ◽  
Brahim Marzouk
Keyword(s):  
Medicinal Plants ◽  
Anticancer Activity ◽  
Scientific Journal ◽  
Public Health Problem ◽  
Review Article ◽  
Major Public Health Problem ◽  
Journal Articles ◽  
Wide Range ◽  
The World ◽  
Different Types

AbstractCancer is a major public health problem in the world. The use of the medicinal plants in cancer prevention and management is frequent in Africa, especially in Tunisia, and it is transmitted from generation to generation within cultures. Many previous studies showed that a wide range of Tunisian medicinal plants exerted cytotoxic and anticancer activity. A comprehensive review was conducted to collect information from scientific journal articles, including indigenous knowledge researches, about Tunisian medicinal plants used for the prevention and management of cancer. The aim of this review article is to provide the reader with information concerning the importance of Tunisian medicinal plants in the prevention and management of cancer and to open the door for the health professionals and scientists working in the field of pharmacology and therapeutics to produce new drug formulations to treat different types of cancer.

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