scholarly journals Antioxidant Parameters, Lipid Profiles and Performance Studies of Broiler Birds Fed Graded Level Taurine-Supplemented Diets

2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Simiat M Ogunbode ◽  
Oladimeji R. A. ◽  
Salaudeen Q. O. ◽  
Bello R. A.
Keyword(s):  
Nitric Oxide ◽  
Defense Mechanisms ◽  
Reduced Glutathione ◽  
Control Diet ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Feed Conversion ◽  
Antioxidant Parameters ◽  
And Performance ◽  
Enzymic Antioxidants

The research was targeted towards monitoring the activities of antioxidant enzymes, levels of non-enzymic antioxidants, lipid profiles and performance activities of broiler birds fed taurine-supplemented diets. One hundred and eighty 1-day-old unsexed arbor acre strain broiler birds were randomly distributed into five dietary treatments, six replicates per treatment and six birds per replicate. Treatments 1 to 5 contained 0%, 0.002%, 0.004%, 0.006% and 0.008% taurine supplements respectively as add-over. Treatment 1 served as the control diet. The birds were grouped and brooded for a week and the experiment lasted for six weeks. The birds were sacrificed and the liver, kidneys and serum were collected. The activities of catalase and myeloperoxidase, concentrations of reduced glutathione and nitric oxide as well as the serum lipid profiles were monitored.  Liver catalase activities was highest for birds placed on 0.006 and 0.008% taurine-supplemented diets as compared with those on 0% taurine-supplemented diet. The trend was similar for the kidney reduced glutathione concentration. Liver nitric oxide concentrations and kidney myeloperoxidase activities were significantly higher (p<0.05) for birds placed on 0.004%, 0.006% and 0.008% taurine-supplemented diets as compared to birds placed on the control diets. High density lipoprotein was highest for birds on a 0.008% diet and lowest for birds on the control diet. The best feed conversion ratio was obtained for birds placed on 0.008% taurine-supplemented diet. Taurine-supplemented diets at between 0.002 and 0.008% favoured birds’ antioxidant defense mechanisms, had no deleterious effect on lipid profile, and equally improved the performance characteristics of broiler birds.

Effect of dietary probiotic, antibiotic or combination on broiler performance, cecum microbial population and ileal development

2020 ◽  
Vol 21 (3) ◽  
pp. 74-79
Author(s):  
Ahmed Elbaz ◽  
Said El-sheikh
Keyword(s):  
Control Diet ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Experimental Period ◽  
Nutrient Digestibility ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Gut Health ◽  
Feed Conversion ◽  
Broiler Performance

Objective: To investigate the effect of antibiotics and/or probiotics on broiler performance, some serum metabolites, cecum microflora composition, and ileum histomorphology under the Egyptian conditions. Design: Randomized controlled experimental study. Animals: Two hundred forty 1-day-old Ross (308) chicks were reared till 35 days of age. Procedures: The birds were randomly allocated into four main groups: a control diet without additives (CON); probiotic (Lactobacillus acidophilus) supplemented diet (PRO); antibiotic (Avilamycin) supplemented diet (ANT) and a mix group (AP) that received antibiotic in the diet form 1 to 4 days of age and treated during the rest of the experimental period with probiotics. Results: Chickens fed on probiotic or antibiotic diets had linear improvement in live body weight (LBW) and feed conversion ratio (FCR) compared with the control group, while the best LBW and FCR were in the AP group. An improvement in the nutrient digestibility was observed in the probiotic added groups (PRO and AP). Serum cholesterol and low-density lipoprotein cholesterol contents decreased when antimicrobial (probiotic or antibiotic) supplementations were used, while there was an increase in high-density lipoprotein cholesterol contents, serum total protein, and albumin levels. Among all groups, cecum Clostridium perfringens and Escherichia coli counts decreased; however, there was an increase in Lactobacillus count compared to the control group. In probiotic supplemented groups (PRO and AP), a significant (P<0.05) improvement in ilea architecture. Conclusion and clinical relevance: Using probiotic after initial treatment with an antibiotic in broiler diets had a positive effect on broiler growth performance, gut health (improved cecum microbial populations and ileum histomorphology), and nutrient digestibility.

Effect of combined treatment with aflatoxin B 1 and T-2 toxin and metabolites on some production traits and lipid peroxide status parameters of broiler chickens

2009 ◽  
Vol 57 (1) ◽  
pp. 75-84 ◽  
Author(s):  
László Pál ◽  
Károly Dublecz ◽  
Mária Weber ◽  
Krisztián Balogh ◽  
Márta Erdélyi ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Reduced Glutathione ◽  
Body Weight Gain ◽  
Control Diet ◽  
Combined Treatment ◽  
Lipid Peroxide ◽  
Control Group ◽  
Production Traits ◽  
Feed Conversion ◽  
Aflatoxin B

Three groups of cockerels were fed with a control diet, with a diet contaminated with T-2 and HT-2 toxin (0.31 and 0.26 mg/kg) or with that containing a combination of T-2 and HT-2 toxin (0.32 and 0.25 mg/kg) and aflatoxin B1(AFB1, 0.38 mg/kg) for 21 days. Body weight gain and feed conversion ratio did not differ significantly among the groups. Malondialdehyde concentration of the liver was lower in the group fed the diet contaminated with the combination of T-2 + HT-2 toxin and aflatoxin B1as compared to the control group or the group fed T-2 + HT-2 toxins. Reduced glutathione (GSH) content of the liver was lower in the T-2 + HT-2 group than in the group fed a combination of T-2, HT-2 and aflatoxin. Reduced glutathione content of the heart was higher in the T-2 + HT-2 group than in the control group. Mycotoxin contamination had no effect on glutathione peroxidase (GSH-Px) activity in comparison to the control, but significantly lower GSH-Px activity was found in the heart of chickens in the T-2 + HT-2 + AFB1group than in the T-2 + HT-2 group. In this study, T-2 + HT-2 toxin and aflatoxin B1contamination of the diets did not affect the production traits adversely and did not exert additive effects on lipid peroxidation and on the glutathione redox system.

scholarly journals Effect of using ginger, red and black pepper powder as phytobiotics with protexin® probiotic on performance, carcass characteristics and some blood biochemical on Japanese quails (Coturnix japonica)

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Yaser Rahimian ◽  
Farshid Kheiri ◽  
Mehdi Moghaddam
Keyword(s):  
Control Diet ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Black Pepper ◽  
Average Weight ◽  
Feed Conversion ◽  
Blood Biochemical ◽  
Japanese Quails ◽  
Pepper Powder ◽  
Black Pepper Powder

This experiment was conducted to evaluate the feeding values of ginger, red and black pepper powder with protexin on performance of Japanese quails. A total 240ten days old male Japanese quails with an average weight of 19 ±5 g were divided into 8 treatments with 3 replicates as randomized factorial design. The quails were fed by basal diet as control diet, 2% ginger, 2%red pepper 2% black pepper powder with or without protexin probiotic respectively. At the end of trial for carcass evaluation 2 birds form each group were slaughtered. Also some parameters such as feed intake (FI), body weight gains (BW), and feed conversion ratio (FCR) were calculated and compared together. Some blood parameters such as cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL) of quail’s blood were determined. In conclusion it seem that inclusion of ginger, red and black pepper powder in quails diet at level of 2% may be useful and have significantly effects on performance and blood biochemical on Japanese quails

scholarly journals Evaluation of a Product Derived from Porcine Plasma Protein and a Yeast Product with Similar Biological Activity in Diets of Growing Broilers

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1751
Author(s):  
Park Waldroup ◽  
Mathew Vaughn ◽  
James McNaughton
Keyword(s):  
Negative Impact ◽  
Control Diet ◽  
High Stress ◽  
Integral Point ◽  
Feed Conversion ◽  
Breast Meat ◽  
Breast Meat Yield ◽  
Stress Environment ◽  
Yeast Product ◽  
And Performance

The post-hatch period of a broiler is an integral point in their development and for the programming of musculoskeletal and immune cells. Therefore, the efficacy of two bioactive protein products, betaGRO® (BG) and celluTEIN® (CT) to impact post-hatch and lifelong development was evaluated. Birds were grown under a low stress environment using clean wood shavings litter and a high stress environment with used litter from a commercial farm that had suffered high mortality. Each additive was fed at 300 g/ton from day 1–14 and 50 g/ton from day 15–42. Growing birds in the high stress environment had a negative impact on performance (p < 0.05); however, addition of either BG or CT successfully mitigated the detriments of the high stress environment (p < 0.05), and in many cases, the performance was equal to or better than the performance of birds on the control diet in the low stress environment. Birds fed BG and CT experienced improvements in 42-day feed conversion, and were more uniform than birds grown consuming the control diet (p < 0.05). Mortality of birds in the high stress environment was reduced by addition of BG or CT (p < 0.05). Addition of BG and CT resulted in improvements in carcass and breast meat yield (p < 0.05). Together, these data suggest that BG and CT can be used interchangeably to improve broiler health and performance.

scholarly journals The Relationship between Endothelial Nitric Oxide Synthase with Dyslipidemia in Coronary Heart Disease

2020 ◽  
Vol 8 (A) ◽  
pp. 537-542
Author(s):  
Eryati Darwin ◽  
Eka Fithra Elfi ◽  
Eva Decroli ◽  
Dwitya Elvira
Keyword(s):  
Nitric Oxide ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Medical Condition ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Control Group ◽  
Protective Function ◽  
The Mean ◽  
The Relationship

BACKGROUND: Dyslipidemia is a medical condition that refers to an abnormal of blood lipids level, most common is hyperlipidemia. Elevation of blood lipid such as cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol, or a low high-density lipoprotein (HDL) cholesterol level induces disturbance of endothelial function. Endothelial dysfunction in dyslipidemia is in large part due to a reduced bioavailability of nitric oxide (NO) which is synthesized by endothelial NO synthase (eNOS) which will trigger the development of atherosclerosis, and increases the risk of coronary heart disease (CHD). AIM: This study aims to determine the relationship of lipid profiles of dyslipidemia with eNOS levels in CHD patients. MATERIALS AND METHODS: This study design was a cross-sectional study. The sample in this study was 26 patients which diagnosed as CHD of outpatients in the department of cardiology of a regional general hospital and fulfilled the inclusion and exclusion criteria. Fifteen healthy individuals who come for the general check-up were included as a control group. Blood samples were collected for measurements of eNOS levels and lipid profiles that carried out according to laboratory standards. Statistical analyses were conducted using analysis of variance and Shapiro–Wilk test. RESULTS: The results of this study showed that eNOS levels in the group of CHD patients (24.174 ± 7.136 ng/ml) were significantly lower (p < 0.05) than those in the control group (72.092 ± 30.065 ng/ml). The mean of triglycerides and HDL levels has a weak correlation with the level of eNOS (p > 0.05). The mean of LDL level has moderately positive correlation with eNOS, while cholesterol has a moderate negative correlation with the level of eNOS (p > 0.05). CONCLUSION: This study concluded that high cholesterol levels and low HDL levels in dyslipidemia condition were correlated with eNOS, which has a protective function in CHD.

scholarly journals High quality cassava peel mash supplemented with direct fed microbial as an alternate source of energy supplement: Effects on performance and blood parameters in growing pig

2020 ◽  
Vol 45 (2) ◽  
pp. 176-184
Author(s):  
A. O. K. Adesehinwa ◽  
A. A. Fatufe ◽  
E. Ajayi ◽  
J. O. Abiola ◽  
O. O. Adeleye ◽  
...  
Keyword(s):  
Body Weight Gain ◽  
Control Diet ◽  
Density Lipoprotein ◽  
Conversion Ratio ◽  
Growing Pigs ◽  
Feed Conversion Ratio ◽  
The Body ◽  
Feed Conversion ◽  
High Quality ◽  
Cassava Peel

The feeding trial was carried out to determine the effect of feeding high quality cassava peel mash (HQCP) with or without multi-strain direct fed microbials (DFM) as replacement for maize in the diet of growing pigs on growth, cost benefit, haematology and serumbiochemical indices. A total of 90 growing pigs with an initial weight of 25.36±0.87 kg were randomly assigned to five dietary treatments in a 2×2+1 factorial arrangement in a completely randomised design. The factors were 2 levels of HQCP (7.5% and 15%), two DFM inclusions and a control diet with neither HQCP nor DFM. Pigs on T1 were given corn (40%) based diet without HQCP, T2 had 18.75% of Maize (7.5kg) replaced by HQCP and T3 had 37.5% of total Maize (15kg) replaced by HQCP. The pigs in T4 were given same diet as in T2 with addition of multi-strain DFM and animals on T5 were given the same diet with those on T3 with addition of multi-strain DFM microbial. Each treatment group had three replicates with six animals per replicate. No significant (P>0.05) difference was observed in the performance characteristics of the growing pigs among the diets. The body weight gain ranged between 10.97 and 13.56 Kg in T5 and T3, respectively. The least feed conversion ratio of 3.98 was observed in T3 while the highest feed conversion ratio (4.77) was observed in T5. All the haematological and serum biochemical indices examined were not significantly (P>0.05) different among the treatments. There was no significant (P>0.05) effect of HQCP, DFM or their interaction on all the haematological parameters analysed. There was significant effect of HQCP and DFM interaction on the serum cholesterol (p=0.0062), high density lipoprotein (p=0.05) and low density lipoprotein (p=0.0018). It can be concluded from this study that growing pigs can utilize HQCP up to 15% in their diet without any adverse effect.

Cardioprotective Effects of Diet with Different Grains on Lipid Profiles and Antioxidative System in Obesity-Induced Rats

2012 ◽  
Vol 82 (2) ◽  
pp. 85-93 ◽  
Author(s):  
Y. Kim ◽  
H. Shin ◽  
S. Lee
Keyword(s):  
Aortic Wall ◽  
Plasma Lipids ◽  
Antioxidant Activities ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Thiobarbituric Acid ◽  
Lipid Profiles ◽  
Dietary Lipids ◽  
Male Rats

In the present study, the nutritional quality of four grains including adlay (AD), buckwheat (BW), glutinous barley (GB), and white rice (WR) were evaluated in terms of plasma lipid parameters, gut transit time, and thickness of the aortic wall in rats. The rats were then raised for 4 weeks on the high-fat diet based on the American Institute of Nutrition-93 (AIN-93 G) diets containing 1 % cholesterol and 20 % dietary lipids. Forty male rats were divided into 4 groups and raised for 4 weeks with a diet containing one of the following grains: WR, AD, BW, or WB. The level of thiobarbituric acid-reactive substances (TBARS) in liver was shown to be higher in rats by the order of those fed WR, AD, GB, and BW. This indicates that other grains decreased oxidative stress in vivo more than WR. The superoxide dismutase, glutathione, glutathione peroxidase, and glutathione reductase levels in the AD, BW, and GB groups were significantly higher than those in the WR group (p < 0.05). Plasma lipid profiles differed significantly according to grain combination, and decreased aortic wall thickness was consistent with the finding of decreased plasma low-density lipoprotein cholesterol (LDL-C) (p < 0.05) and increased high-density lipoprotein (HDL-C) in rats fed AD, BW, and GB (p < 0.001). The antioxidant and hypolipidemic capacities of grains are quite high, especially those of adlay, buckwheat, and glutinous barley. In conclusion, this study has demonstrated that the whole grains had a cardioprotective effect. This effect was related to several mechanisms that corresponded to lowering plasma lipids, decreasing TBARS, and increasing antioxidant activities.

Variations in the Lipid Profile of Patients with Chronic Renal Failure, Treated with Folic Acid

2003 ◽  
Vol 73 (3) ◽  
pp. 215-220 ◽  
Author(s):  
de Gómez Dumm ◽  
Giammona ◽  
Touceda
Keyword(s):  
Renal Failure ◽  
Folic Acid ◽  
Chronic Renal Failure ◽  
Density Lipoprotein ◽  
Plasma Homocysteine ◽  
Lipid Profiles ◽  
Erythrocyte Membranes ◽  
Favorable Effect ◽  
High Dose ◽  
Acid Therapy

Dyslipidemia and increases in plasma homocysteine usually occur at end-stage renal disease; both are recognized as risk factors for atherosclerosis. Folate administration reduces homocysteine concentration. In this study we determined the effect of a high dose of folic acid (40 mg intravenous injection three times a week) on plasma and red blood cell lipid profiles in twelve chronic renal failure patients on regular hemodialysis. Fasting blood samples were taken at the beginning of the study (baseline) and after 21, 42, and 64 days of treatment. Folic acid supplementation decreased plasma homocysteine. Plasma triglyceride levels decreased whereas polyunsaturated fatty acid values increased after 21 days; then they returned to baseline levels at the end of treatment. Total cholesterol and low-density lipoprotein (LDL) cholesterol were higher than those of the baseline during all the study, whereas high-density lipoprotein (HDL) cholesterol was reduced. In erythrocyte membranes, folic acid therapy enhanced cholesterol/phospholipid ratios and the fluorescence anisotropy of diphenyl-hexatriene. We conclude that large doses of folic acid produce a favorable effect, reducing plasma homocysteine levels and protecting patients from atherosclerosis. However, as this therapy induces significant alterations in both plasma and erythrocyte membrane lipid profiles, plasma lipid values should be controlled throughout the treatment of patients with renal failure.

Astaxanthin, the Natural Antioxidant, Reduces Reserpine Induced Depression in Mice

2020 ◽  
Vol 16 (9) ◽  
pp. 1319-1327
Author(s):  
Ferdous Khan ◽  
Syed A. Kuddus ◽  
Md. H. Shohag ◽  
Hasan M. Reza ◽  
Murad Hossain
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Reduced Glutathione ◽  
Forced Swim Test ◽  
Tail Suspension Test ◽  
Glutathione Depletion ◽  
Swim Test ◽  
Stress Markers ◽  
Immobility Time ◽  
Biochemical Level

Background: An imbalance between pro-oxidants and antioxidants determines the level of oxidative stress which is implicated in the etiopathogenesis of various neuropsychiatric disorders including depression. Therefore, treatment with antioxidants could potentially improve the balance between pro-oxidants and antioxidants. Objective: The objective of this study was to evaluate the ability of astaxanthin, a potential antioxidant, to reduce reserpine-induced depression in BALB/c mice (Mus musculus). Methods: On the behavioral level, antidepressant property of astaxanthin (50 mg/kg, orally) on reserpine (2 mg/kg, subcutaneously) induced depressed mice was evaluated by Forced Swim Test (FST) and Tail Suspension Test (TST). In the biochemical level, the ability of astaxanthin to mitigate reserpine-induced oxidative stress was evaluated by the measurement of Malondialdehyde (MDA) and nitric oxide (NO) in brain, liver and plasma samples. On the other hand, the efficiency of astaxanthin to replenish glutathione depletion and antioxidant enzyme activity augmentation in the same samples were also investigated. Results: Astaxanthin was able to lower reserpine induced immobility time significantly (p<0.05) in FST and TST. Mice treated with astaxanthin showed significantly (p<0.05) low level of oxidative stress markers such as Malondialdehyde (MDA), Nitric Oxide (NO). Consistently, the level of reduced Glutathione (GSH), and the activity of Superoxide Dismutase (SOD) and catalase were augmented due to the oral administration of astaxanthin. Conclusion: This study suggests that astaxanthin reduces reserpine-induced oxidative stress and therefore might be effective in treating oxidative stress associated depression.

scholarly journals Arginase Isoform Expression in Chronic Rhinosinusitis

2019 ◽  
Vol 8 (11) ◽  
pp. 1809 ◽  
Author(s):  
Diana Vlad ◽  
Silviu Albu
Keyword(s):  
Nitric Oxide ◽  
Chronic Rhinosinusitis ◽  
Defense Mechanisms ◽  
Upper Airway ◽  
Control Group ◽  
Mrna Levels ◽  
Tissue Samples ◽  
Endoscopic View ◽  
Important Regulator ◽  
Arginase I

Nitric oxide (NO) has emerged as an important regulator of upper airway inflammation, mainly as part of the local naso-sinusal defense mechanisms. Increased arginase activity can reduce NO levels by decreasing the availability of its precursor, L-arginine. Chronic rhinosinusitis (CRS) has been associated with low levels of nasal nitric oxide (nNO). Thus, the present study investigates the activity of arginase I (ARG1) and II (ARG2) in CRS and its possible involvement in the pathogenesis of this disease. Under endoscopic view, tissue samples of pathologic (n = 36) and normal (n = 29) rhinosinusal mucosa were collected. Arginase I and II mRNA levels were measured using real-time PCR. Our results showed low arginase I activity in all samples. The levels of ARG2 were significantly higher in patients with chronic rhinosinusitis compared to the control group (fold regulation (FR) 2.22 ± 0.42 vs. 1.31 ± 0.21, p = 0.016). Increased ARG2 expression was found in patients with CRS without nasal polyposis (FR 3.14 ± 1.16 vs. 1.31 ± 0.21, p = 0.0175), in non-allergic CRS (FR 2.55 ± 0.52 vs. 1.31 ± 0.21, p = 0.005), and non-asthmatic CRS (FR 2.42 ± 0.57 vs. 1.31 ± 0.21, p = 0.028). These findings suggest that the upregulation of ARG2 may play a role in the pathology of a distinctive phenotype of CRS.

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