scholarly journals The Complaints Feed By Breast Cancer Patients Based On Stadium And Duration Of Chemotherapy In Waled General Hospital Cirebon District

2019 ◽  
Vol 6 (2) ◽  
pp. 31-38
Author(s):  
Retna Ayu Pengasih ◽  
Dewi Erna Marisa ◽  
Citra Setyo Dwi Andhini
Keyword(s):  
Breast Cancer ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
Public Hospital ◽  
Statistical Tests ◽  
Sampling Technique ◽  
Total Sample ◽  
Breast Cancer Patients ◽  
Breast Cancer Rate ◽  
Quantitative Descriptive

Breast cancer is a malignancy in cells found in breast tissue that can originate from the glandular components (epithelial tracts or lobules) as well as components other than such as fat tissue, blood vessels, and nerve tissue.In Indonesia, there are two types of cancer most commonly suffered by Indonesia people, namely breast cancer and cervical cancer. There is breast cancer rate of 42,1 by 100.000 population and cervical cancer of 23,4 by 100.000 population with an average death of 13,9 by 100.000 population. In Waled Regional Public Hospital Cirebon District, from 2018, 32 breast cancer patients were obtained. This study was conducted to determine complaints in cancer patients based on the stage and duration of chemotherapy at Waled Waled Regional Public Hospital Cirebon District.  This type of research is a quantitative descriptive study using a retrospective. The sampling technique used is the total sample of 32 respondents. Statistical tests were performed by univriat analysis. This research was conducted at Waled Regional Public Hospital Cirebon District. The results of this study indicate all complaints of breast cancer sufferers in Cirebon District Hospital that are less tolerable at stage IIB (100%) which supports moderate chemotherapy (100%).  During chemotherapy treatment, nurses monitor patients about changes in complaints experienced by patients.

scholarly journals Family Support and Self-Esteem of Patient with Breast Cancer

2020 ◽  
Author(s):  
Jek Amidos Pardede ◽  
Marthalena Simamora ◽  
Galvani Volta Simanjuntak
Keyword(s):  
Breast Cancer ◽  
Family Support ◽  
Cancer Patients ◽  
Sampling Technique ◽  
Total Sample ◽  
Self Esteem ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Sample Number ◽  
Spearman Test

Background: Breast cancer brings negative impacts to women, particularly thosewho have undergone chemotherapy, not only physically but also mentally. The negativeimpacts on patients’ mental include a feeling of being failed to play their role as a woman,not having the ability to do anything, low self-esteem, and confidence loss. Thus, familysupport is necessary for anticipating negative self-esteem in breast cancer patients. Familysupport helps patients maintain and increase their self-esteem. Objective: The objectiveof this study is to analyze the relationship between family support and self-esteem inpatients with breast cancer undergoing chemotherapy at Haj Adam Malik Central Hospital.Methods: The study employed analytical correlational design with a cross-sectional approach.The research samples included all breast cancer patients who were undergoingchemotherapy at Haj Adam Malik Central Hospital in Medan City. The sampling selectionof this study used total sampling technique; hence the total sample number was 34.Spearman test was performed in data analysis. Result: The study suggested that 64.7% ofthe respondents received good family support and 66.7% of the respondents had a high levelof self-esteem. Besides, it was also obtained that there was a moderate correlation betweenfamily support and self-esteem of patients with breast cancer (p=0.01< α 0,05 with r =0.432). The results imply that better family support is the higher the level of self-esteemof patients with breast cancer undergoing chemotherapy will be. Therefore, it isrecommended that each of the family members gives support to the patient in the form of care,information, and instrumental support, so that the patient will have better self-esteem andquality of life

scholarly journals LEMON AROMATHERAPY AS AN ALTERNATIVE TO REDUCE THE INTENSITY OF CHEMOTHERAPY-RELATED NAUSEA AND VOMITING EXPERIENCED BY THE BREAST CANCER PATIENTS

2021 ◽  
Vol 5 (2) ◽  
pp. 125-130
Author(s):  
Puji Hastuti ◽  
Yuli Nurhayati ◽  
Dwi Ernawati ◽  
Christina Yuliastuti ◽  
Merina Widyastuti
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Sampling Technique ◽  
Complementary Therapy ◽  
Nausea And Vomiting ◽  
Wilcoxon Test ◽  
Control Group ◽  
Breast Cancer Patients ◽  
Post Test ◽  
Abnormal Tissue

ABSTRACT Introduction : The mechanism of breast cancer is the cells growing and breeding become appear abnormal tissue of breast. One of the common treatments for it is chemotherapy using cytotoxic drugs. However, chemotherapy may cause nausea and vomiting as its side effects. Lemon aromatherapy is a complementary therapy in patients with breast cancer who experience nausea or vomiting. The study’s purpose was to know the effect of lemon aromatherapy on the intensity of nausea and vomiting experienced by the breast cancer patients as an effect of chemoterapy in the Chemo Center Room of RSAL Dr. Ramelan Surabaya. Material and Methods : The study was the pre-experimental design with pre-post test without control group. There are two variables, lemon aromatherapy is independent, and the intensity of nausea and vomiting is dependent. The sampling technique was nonprobability purposive sampling, with 34 breast cancer patients taken as the sample. A questionnaire was the instrument for collecting the data. The Data collected were analyzed using the Wilcoxon Test (α = 0,05). Results : The study’s result indicated that the lemon aromatherapy was effectively to decrease of the intensity of nausea and vomiting exeperienced by the respondents, with the value of Wilcoxon test p < 0.001. Conclusion : Lemon aromatherapy stimulates the raphe nucleus to produce serotonin. Which function to generate a sense of comfort and calm. For that reason, it can be used as an alternative for taking care of nausea and vomiting experienced by patients with breast cancer as the side effect of chemotherapy. Keywords:  Lemon Aromatherapy, Nausea, Vomiting, Chemotherapy  

scholarly journals Hubungan Dukungan Keluarga Terhadap Kualitas Hidup Pasien Kanker Payudara di Rumah Sakit Islam Siti Khodijah Palembang Tahun 2018

2019 ◽  
Vol 19 (3) ◽  
pp. 529
Author(s):  
Yofa Anggriani Utama
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Developing Countries ◽  
Family Support ◽  
Cancer Patients ◽  
Sampling Technique ◽  
P Value ◽  
Breast Cancer Patients ◽  
The World

Cancer is one of the causes of death in both developed and developing countries, cancer is increasing in developing countries due to increasing lifestyle, breast cancer is a cancer that causes death in women in the world, breast cancer is the highest contributor to mortality in women in the world, 43.3 per 100,000. The purpose of this study was to determine the relationship of family support to the quality of life of breast cancer patients. The research design used was observational analytic with cross sectional approach. The sampling technique used purposive sampling technique, the study sample amounted to 63 breast cancer patients. The results show that there is a relationship between family support and the quality of life of breast cancer patients with a p value of 0.032. shows there is a relationship between family support for the quality of life of patients with breast cancer. Suggestions that nurses can improve the quality of nursing services, and provide motivation to patients and families of breast cancer in carrying out breast cancer treatment.

scholarly journals Late Stage Diagnostic of Breast Cancer at RSUD Arifin Achmad of Riau Province 2016

2018 ◽  
Vol 4 (1) ◽  
pp. 33-39
Author(s):  
Titiana Yuswar ◽  
Nurlisis Nurlisis
Keyword(s):  
Breast Cancer ◽  
Health Service ◽  
Cancer Patients ◽  
Public Hospital ◽  
Community Health Centers ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Cancer Knowledge ◽  
Cross Sectional ◽  
Keywords Screening

ABSTRACT   Breast cancer examination delays is a condition where breast cancer patients come to know their condition exceeds the specified time (cancer stage III)  when cancer can not differentiate well to get treatment. In Indonesia, almost 70% of breast cancer patients are too late to do examination. Data at Arifin Achmad Regional Public Hospital show increasing number of breast cancer cases, where in 2012 there were 145 cases, in 2013 there were 262 cases and in 2014 there were 584 cases. This research aims to know the factors that related to breast cancer examination delays such as knowledge, education, income, pain, fear, family support, BSE (breast elf examination), distance to health service, resources and family history of breast cancer. The research type is quantitative analytic observational. The research design is analytic cross sectional study. The populations are outpatients women with breast cancer who came to Arifin Achmad regional public hospital Riau Province and total sampel are 203 women. The data were analyzes by univariat, bivariat analyzes by chi square and multivariat analyzes by multiple logistic regression. The results of this research show that knowledge effect 3 times, income effect 3 times, distance to health service effect 2,5 times and pain effect 2 times to breast cancer examination delays. The conclusions of this study are there are casual link between knowledge, income, distance to health service and pain to breast cancer examination delays. Recommended to women to improve their knowledge about breast cancer examination and suggested to Health Departement of Riau Province through community health centers to give education and socialization about breast cancer to community.   Keywords: Screening Delays, Breast Cancer, Knowledge, Income, Distance  

scholarly journals Spiritual Distress In Breast Cancer Patients

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Puji Lestari ◽  
Aan Nuraeni ◽  
Dyah Setyorini
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Assessment Tool ◽  
Sampling Technique ◽  
Spiritual Needs ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Life Balance ◽  
Spiritual Distress ◽  
Values And Beliefs

Breast Cancer would affect all aspects of patients’ life including spiritually. This aspect is one of the patients’ main coping sources in dealing with impacts of the disease. However, the spiritual aspect is rarely noticed by nurses, and may lead to patients’ spiritual distress. This study aimed to determine spiritual distress in breast cancer patients who had treatments in a referral hospital in West Java. This study was a descriptive quantitative with cross-sectional approach. The population was in-patient breast cancer patients. Respondents were chosen using the accidental sampling technique. During a month period, 37 patients involved in this study. The data was collected using an instrument which was developed from Spiritual Distress Assessment Tool (SDAT) and analyzed using descriptive quantitative analysis.  Almost two-thirds (62.2%) of respondents had low spiritual distress, 32.2% of respondents had moderate spiritual distress and a very small number of respondents (5.4%) had severe spiritual distress. In the term of spiritual distress dimension, “life balance” had the highest mean score (1.86) and the lowest was in “values and beliefs with sub-dimension of need maintain control” (0.89). The conclusion was the majority of patients had low spiritual distress, yet spiritual distress for moderate to severe still could be found in smaller proportion. Life balance was dimension with the highest level of spiritual distress.  The patients’ spiritual need would be achieved when patients have a good acceptance and adaptation. Nurses have a role to encourage patients’ acceptance of their illnesses through improvement of the fulfillment of the patient's spiritual needs.

scholarly journals Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, p16INK4a

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Shlomit S Shachar ◽  
Allison M Deal ◽  
Katherine E Reeder-Hayes ◽  
Kirsten A Nyrop ◽  
Natalia Mitin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Chemotherapy Regimen ◽  
Early Stage ◽  
Statistical Tests ◽  
Accelerated Aging ◽  
Early Stage Breast Cancer ◽  
Breast Cancer Patients ◽  
Aging Effects ◽  
P16ink4a Expression

Abstract Background Although chemotherapy saves lives, increasing evidence shows that chemotherapy accelerates aging. We previously demonstrated that mRNA expression of p16INK4a, a biomarker of senescence and molecular aging, increased early and dramatically after beginning adjuvant anthracycline-based regimens in early stage breast cancer patients. Here, we determined if changes in p16INK4a expression vary by chemotherapy regimen among early stage breast cancer patients. Methods We conducted a study of stage I-III breast cancer patients receiving adjuvant or neoadjuvant chemotherapy. p16INK4a expression was analyzed prechemotherapy and postchemotherapy (median 6.2 months after the last chemotherapy) in peripheral blood T lymphocytes. Chemotherapy-induced change in p16INK4a expression was compared among regimens. All statistical tests were 2-sided. Results In 146 women, chemotherapy was associated with a statistically significant increase in p16INK4a expression (accelerated aging of 17 years; P &lt; .001). Anthracycline-based regimens were associated with the largest increases (accelerated aging of 23 to 26 years; P ≤ .008). Nonanthracycline-based regimens demonstrated a much smaller increase (accelerated aging of 9 to 11 years; P ≤ .15). In addition to the type of chemotherapy regimen, baseline p16INK4a levels, but not chronologic age or race, were also associated with the magnitude of increases in p16INK4a. Patients with lower p16INK4a levels at baseline were more likely to experience larger increases. Conclusions Our findings suggest that the aging effects of chemotherapy may be influenced by both chemotherapy type and the patient’s baseline p16INK4a level. Measurement of p16INK4a expression is not currently available in the clinic, but nonanthracycline regimens offering similar efficacy as anthracycline regimens might be favored.

Natural HPV58 E6 and E7 Variants Detected in Thai Breast Cancer Patients Cooperate to Induce Loss of p53 and Increase Cell Growth

2021 ◽  
Vol 104 (6) ◽  
pp. 902-910
Keyword(s):  
Breast Cancer ◽  
Cervical Cancer ◽  
Cell Proliferation ◽  
Human Papillomavirus ◽  
Cell Growth ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Breast And Cervical Cancer ◽  
Cervical Cancer Cells ◽  
Hpv Oncoproteins

Background: Detection of human papillomavirus (HPV) in breast cancer patients has suggested a possible contributing role of the virus in cancer progression in this population. Objective: To investigate the presence of HPVs in Thai breast cancer patients and examine the potential activities of HPVs identified in both breast and cervical cancer cells. Materials and Methods: Fifty-five breast cancer tissues from Thai patients were subjected to HPV detection using PCR-EIA and DNA sequencing. Detection of HPV E6 proteins in sample tissues was examined by fluorescence immunohistochemistry. Cervical and two types of breast cancer cell lines expressing HPV oncogenes were established. The separate and combination of HPV oncoproteins activity for p53 degradation and specific gene regulation were investigated using western blot analysis and qPCR. Cell proliferation was assessed by MTT assay. Results: Twenty-two percent (10/45) of invasive breast cancers were found infected with various high-risk HPV types, with HPV58 E6D4G/E7T20IG63S being the most common variant. The percentage of HPV58 alone was approximately 50% (5/10) of all HPV positive samples. Similar potential oncogenic activity for this variant was observed in breast and cervical cancer cells. A separate analysis of single or combination of 58E6 (prototype or E6D4G) with 58E7 (prototype or E7T20IG63S) demonstrated that co-expression of 58E7T20IG63S with 58E6 (either prototype or E6D4G) significantly promoted cell proliferation compared to prototype 58E6/E7. Enhanced proliferation was mediated through elevated p53 degradation and reduced p21 expression. While p53 degradation activity was greatly diminished from E6 with D4G mutation, co-expression with E7T20IG63S cooperated to enhance degradation of p53 and promoted cell growth. Conclusion: HPV58 E6D4G/E7T20IG63S was the most HPV oncogene variant detected in Thai breast cancer patients. This variant exhibited in promoting cell proliferation and p53 degradation. A cooperative effect was observed in combination of HPV oncoproteins. Keywords: Human papillomavirus type 58; oncogene variant; breast cancer; Thai patients; altered cell growth

scholarly journals BREAST CANCER PATIENTS’ COMPLIANCE ON CHEMOTHERAPY: A DESCRIPTIVE STUDY

2019 ◽  
Vol 2 (3) ◽  
Author(s):  
Vici Triyunita Sabiyanto ◽  
Restuning Widiasih ◽  
Tetti Solehati
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Univariate Analysis ◽  
Sampling Technique ◽  
Breast Cancer Patients ◽  
Halfway House ◽  
Breast Cancer Therapy ◽  
Patient Factors ◽  
Halfway Houses ◽  
Therapy Compliance

Breast cancer is the most women cancer in the world, including Indonesia. Some patients stop breast cancer treatment which is impacted to patients' conditions. In chronic diseases, therapy compliance is important for reach successful therapy however study that assess breast cancer patients’ compliance on chemotherapy is limited. The purpose of this study was to describe patient factors that can affect therapy compliance. This research used descriptive quantitative method and respondents were chosen using the accidental sampling technique. The data were gathered at one of the halfway houses in Bandung. Data were collected using a questionnaire. Data were analyzed by univariate analysis and described by frequency distribution. The results showed that 26 respondents (84%) were obedient to chemotherapy. There were 28 respondents (90.3%) because they did not carry out alternative medicine and 26 respondents (83.9%) had because they put aside work and related affairs to do chemotherapy. In conclusion, the majority of respondents were obedient to chemotherapy. There are patient factors that can improve chemotherapy compliance, there are chosen therapy factor and demographic and economic factors. Development of another halfway houses could be carried out, because of the result of this research, representing many breast cancer patients feels easier to obedient the sequence of therapy.Keywords: Breast cancer, therapy compliance, halfway house.

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