Beneficial Effects of Ashitaba (Gynura nepalensis): Users’ Testimonies

2013 ◽  
Vol 6 (1) ◽  
Author(s):  
FLORIDA U. URSULOM ◽  
ANICETO R. RIALUBIN
Keyword(s):  
Social Sciences ◽  
The Philippines ◽  
Health Maintenance ◽  
Beneficial Effects ◽  
The Poor ◽  
Anti Cancer ◽  
Angelica Keiskei ◽  
Anti Oxidant ◽  
Quota Sampling ◽  
Descriptive Method

Ashitaba (Gynura nepalensis, Gynura procumbens, Gynura acutifolia) is the ashitaba grown in the Philippines. Ashitaba (Angelica keiskei Kodzumi) originated in the Island of Hachijo, Japan. Both ashitaba have been studied by researchers using animals and in test tubes and have been claimed to be anti-oxidant, anti-cancer, antiaging, anti-inflammatory, antihypertensive, and anti-diabetic. Generally, this study aimed to widen the dissemination of the beneficial effects of ashitaba (Gynura nepalensis) based from testimonies of users. This study utilized the descriptive method of research with data presented in tabular form and analyzed in textual manner, used quota sampling, interview with guide questions, and frequency and percentage and rank. Findings showed that giving a lighter and healthier feeling, emitting stomach gas and giving a lighter feeling, and giving energy ranks 1, 2, and 3, respectively; on the other hand, aiding in dialysis, treating pharyngitis, goiter, and pain in nipples ranks last among the testimonies of respondents. Based on findings, it is concluded that ashitaba (G. nepalensis), is a health enhancer, medicine and good for health maintenance. Further, it is recommended that the result of this study be widely disseminated to be of help particularly to the poor, rich, pharmacologists, food businessmen, researchers, and other interested identities.Keywords: Social Sciences, Gynura nepalensis, Gynura precumbens, Angelica keiskei Kodzumi,quota sampling, Philippines

scholarly journals The Beneficial Effects of Principal Polyphenols from Green Tea, Coffee, Wine, and Curry on Obesity

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 453
Author(s):  
Tomokazu Ohishi ◽  
Ryuuta Fukutomi ◽  
Yutaka Shoji ◽  
Shingo Goto ◽  
Mamoru Isemura
Keyword(s):  
Green Tea ◽  
Animal Studies ◽  
Epigallocatechin Gallate ◽  
Nuclear Factor Κb ◽  
Epidemiological Studies ◽  
Ros Generation ◽  
Beneficial Effects ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Amp Activated Protein Kinase

Several epidemiological studies and clinical trials have reported the beneficial effects of green tea, coffee, wine, and curry on human health, with its anti-obesity, anti-cancer, anti-diabetic, and neuroprotective properties. These effects, which have been supported using cell-based and animal studies, are mainly attributed to epigallocatechin gallate found in green tea, chlorogenic acid in coffee, resveratrol in wine, and curcumin in curry. Polyphenols are proposed to function via various mechanisms, the most important of which is related to reactive oxygen species (ROS). These polyphenols exert conflicting dual actions as anti- and pro-oxidants. Their anti-oxidative actions help scavenge ROS and downregulate nuclear factor-κB to produce favorable anti-inflammatory effects. Meanwhile, pro-oxidant actions appear to promote ROS generation leading to the activation of 5′-AMP-activated protein kinase, which modulates different enzymes and factors with health beneficial roles. Currently, it remains unclear how these polyphenols exert either pro- or anti-oxidant effects. Similarly, several human studies showed no beneficial effects of these foods, and, by extension polyphenols, on obesity. These inconsistencies may be attributed to different confounding study factors. Thus, this review provides a state-of-the-art update on these foods and their principal polyphenol components, with an assumption that it prevents obesity.

scholarly journals Nutraceutical and Pharmacological Appraisal of Āmla (Emblica officinalis Gaertn.): A Review

2019 ◽  
pp. 1-13
Author(s):  
Mohammad Fazil ◽  
Sadia Nikhat
Keyword(s):  
Biologically Active ◽  
Emblica Officinalis ◽  
Active Components ◽  
Tropical Regions ◽  
Unani Medicine ◽  
Beneficial Effects ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Dose Dependent ◽  
Pale Green

Āmla (Emblica officinalis Gaertn, Family: Euphorbiaceae) is a medicinally important plant indigenous to tropical and sub-tropical regions of South-east Asia. The tree is 5-25 metres tall, deciduous, having deltoid-squamiform leaves and bears pale-green globose fruits 2-4 cm in diameter. In Unani medicine, it is widely used in compound formulations or in raw form in many disorders of central nervous system, gastro-intestinal system, skin, hair, general debility etc. In Ayurveda, it is classified as a rasayana, i.e., drugs which promote longevity and delay ageing. Āmla fruit is one of the richest sources of Vitamin C (478.56 mg/ 100 ml), alongwith important constituents such as gallic acid, ellagic acid, iron, magnesium, phosphorous, potassium etc. recent researches on Āmla have revealed the presence of several biologically active substances with scientifically proven effects as anti-oxidant, anti-ageing, immunomodulatory, memory enhancing, protective towards vital organs such as liver, heart kidneys; anti-depressant, anti-cancer and many more beneficial effects. Most of the experiments have been carried out on Āmla fruit and are dose-dependent. Moreover, no toxic effects have been reported in any of the studies. This review focuses on the various biologically active components of Āmla and its relevance in modern pharmacology.

PENERAPAN STRATEGI PEMBELAJARAN GO TO YUOR POST UNTUK MENINGKATKAN HASIL BELAJAR IPS SISWA KELAS VI SDN 024 TARAI BANGUN KECAMATAN TAMBANG KABUPATEN KAMPAR

2017 ◽  
Vol 1 (1) ◽  
pp. 85
Author(s):  
Delfi Yendri
Keyword(s):  
Social Sciences ◽  
Data Collection ◽  
Student Learning ◽  
Learning Outcomes ◽  
Learning Strategies ◽  
Student Learning Outcomes ◽  
Student Activity ◽  
The Poor ◽  
The Subject ◽  
Data Collection Activity

This research is motivated by the poor results of Study Social Sciences (IPS) Student Class VI SDN 024 Tarai Bangun Kecamatan Tambang. This study aims to determine the resulting increase studying social sciences (IPS) student class VI SDN 024 Tarai Bangun Kecamatan Tambang through the application of learning strategies go to yuor post, which carried out for 1 month. The subjects were VI SDN 024 Tarai Bangun Kecamatan Tambang by the number of students as many as 38 people. Form of research is classroom action research. The research instrument consists of instruments and instrument performance data collection activity observation sheet form teacher and student activity. Based on the research, the conclusion to this study is based on the analysis and discussion in chapter IV can be concluded that the application of learning strategies go to yuor post can improve learning outcomes in the subject of social sciences grade VI SDN 024 Tarai Bangun Kecamatan Tambang. Evidenced by the increase in learning outcomes before action to the first cycle, to cycle II. Before the act of student learning outcomes classified as unresolved with an average of 59%, an increase in the first cycle by an average of 69%. While the results of student learning in the second cycle must be increased by an average of 75% with the category completed.

Pharmacological study on the possible involvement of a Nrf2 -Heme oxygenase pathways in anti-cataract activity of fisetin

2020 ◽  
Vol 10 (1) ◽  
pp. 14-19
Author(s):  
Krishna Reddy BV ◽  
Avinash Kumar Reddy G ◽  
Sujitha V ◽  
Manasa A
Keyword(s):  
Oxidative Stress ◽  
Heme Oxygenase ◽  
Pharmacological Study ◽  
World Population ◽  
Central Feature ◽  
Beneficial Effects ◽  
Radical Production ◽  
Anti Oxidant ◽  
Diabetic Population ◽  
Oxidant Status

DM otherwise diabetes is now a days an epidemic with the percentage of patient population rising to almost 10% of the world population. Out of all the DM complications, cataract leads the way contributing to disabilities to about 60% of diabetic population. But the pathogenesis of DM cataract is still a half-understood area of medicine there by posing a problem in the therapy. The data that we have till now gives us enough evidence to advocate the oxidative stress has a major role for the pathogenesis of DM complications like DMnephropathy, DMneuropathy, and cardiac hypertrophy, which suggests the oxidative stress is a central feature of diabetes. In the current research, the pharmacological evaluation of Fisetin for its DM based anti-cataract property was performed. This research concentrates to estimate the possible involvement of Nrf-2 / heme oxygenase (HO)-pathway in the observed therapeutic effect, if any. The data obtained in this study also indicate that the observed beneficial effects mainly due to activation of Nrf2/HO-1 pathway. These effects probably result in increased tissue anti-oxidant status as well as decreased free radical production, which ultimately responsible for the observed beneficial effects of Fisetin against hyperglycemia-induced cataract.

Role of Rasayan Churna in outbreak of Covid -19 as preventive and curative aspect

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1208-1212
Author(s):  
Amol Madhav Deshpande ◽  
Mayuri Amol Deshpande
Keyword(s):  
Recurrent Infection ◽  
Symptomatic Patient ◽  
H1n1 Influenza ◽  
Drug Of Choice ◽  
Asymptomatic Patients ◽  
Diseased Person ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Immune Booster ◽  
Respiratory Droplets

In last two decade world suffer with three epidemic diseases like SARS-CoV, H1N1 influenza, MERS –CoV and presently the world under a pandemic of Covid-19, out of these SARS-CoV, MERS –CoV and Covid-19 are form the same virus call as corona, which primary present on bats and transferred from animal to human, and then it transfer from human to human mostly by respiratory droplets or in the direct contact with the diseased person, these recurrent infection of corona virus is the burning issue in the word, so to avoid these recurrent infections good habitual behaviour with regular immune booster medicine should be taken which can be used in both normal and symptomatic patient for this Rasayan churna  is the best drug of choice as it is used for  rejuvenation therapy. From literally study from various recourses it is found that Rasayan churna have property anti-depressant, anti-xylotic, Immunomodulatory, Anti-diabetes, anti hypertensive, anti-inflammatory, Anti-toxic effects, Anti-arthritic, Anti-cancer effects, Anti-microbial effect, and Anti-oxidant which can be useful in preventive aspect of Covid -19 in all phase like normal individual, also can be used in asymptomatic patients and symptomatic patients, clinical study can be performed for the same to evaluate the result.

1,4-Dihydropyridine: A Dependable Heterocyclic Ring with the Promising and the Most Anticipable Therapeutic Effects

2019 ◽  
Vol 19 (15) ◽  
pp. 1219-1254 ◽  
Author(s):  
Abhinav Prasoon Mishra ◽  
Ankit Bajpai ◽  
Awani Kumar Rai
Keyword(s):  
Calcium Ion ◽  
Heterocyclic Compounds ◽  
Channel Blocker ◽  
Heterocyclic Ring ◽  
Therapeutic Effects ◽  
Voltage Gated ◽  
Therapeutic Benefits ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Synthetic Medicinal

: Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal chemistry. Among all of the heterocyclic scaffolds, 1,4-Dihydropyridine (1,4-DHP) is one of the most important heterocyclic rings that possess prominent therapeutic effects in a very versatile manner and plays an important role in synthetic, medicinal, and bioorganic chemistry. The main aim of the study is to review and encompass relevant studies related to 1,4-DHP and excellent therapeutic benefits of its derivatives. An extensive review of Pubmed-Medline, Embase and Lancet’s published articles was done to find all relevant studies on the activity of 1,4-DHP and its derivatives. 1,4-DHP is a potent Voltage-Gated Calcium Channel (VGCC) antagonist derivative which acts as an anti-hypertensive, anti- anginal, anti-tumor, anti-inflammatory, anti-tubercular, anti-cancer, anti-hyperplasia, anti-mutagenic, anti-dyslipidemic, and anti-ulcer agent. From the inferences of the study, it can be concluded that the basic nucleus, 1,4-DHP which is a voltage-gated calcium ion channel blocker, acts as a base for its derivatives that possess different important therapeutic effects. There is a need of further research of this basic nucleus as it is a multifunctional moiety, on which addition of different groups can yield a better drug for its other activities such as anti-convulsant, anti-oxidant, anti-mutagenic, and anti-microbial. This review would be significant for further researches in the development of several kinds of drugs by representing successful matrix for the medicinal agents.

Effects of Minor Compounds of Edible Oils on Human Health

2020 ◽  
Vol 16 (8) ◽  
pp. 1196-1208
Author(s):  
Ramin Ghodsi ◽  
Rahmat Nosrati
Keyword(s):  
Human Health ◽  
Food Industry ◽  
Edible Oils ◽  
Food Groups ◽  
Bioactive Constituents ◽  
Beneficial Effects ◽  
Anti Cancer ◽  
Prevention And Treatment ◽  
Minor Compounds ◽  
Anti Inflammation

Background: Oils and fats are the densest sources of food energy among food groups. Vegetable oils are constituted predominantly of triglycerides. Due to the importance of edible oils in nutrition, food industry and human health, great attention has been paid to them in recent years. Some minor bioactive constituents in oils include phospholipids, tocols, sterols, carotenoid, chlorophyll, phenols, phylokynon and terpenes. Objective: The aim of the present study was to examine beneficial effects of minor compounds in edible oils on human health. Results: Minor compounds of edible oils that we use daily can produce remarkable results in the prevention and treatment of various diseases like diabetes, inflammation, hypertension, cancer, allergy and central nervous system disorders due to their antimicrobial, anti-cancer, anti-viral, anti-oxidative, anti-inflammation, anti-mutagenic, hypolipidemic, and hypoglycemic properties, among others. Conclusion: The results of this study showed that the presence of beneficial minor compounds in oils could have significant impact on the prevention and treatment of various diseases. Therefore, the type of consumed oil can play an important role in human health.

Poverty and Penia

2017 ◽  
Author(s):  
Claire Taylor
Keyword(s):  
Social Sciences ◽  
Theoretical Approach ◽  
Ancient World ◽  
The Poor ◽  
The Social ◽  
Methodological Problems ◽  
Previous Scholarship

This chapter lays out the theoretical approach for the book and discusses the methodological problems of writing about poverty and the poor in the ancient world. Whilst studying the lives of the poor in the ancient world is to some extent elusive, it argues that historians can do more than simply imagine this group of people back into the gaps left by other evidence. As well as reviewing previous scholarship on poverty in the ancient world, it suggests a way forward which is more in line with contemporary poverty research within the social sciences.

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