scholarly journals Complete Blood Count (CBC) Status among Hypertensive Subjects in Isiala Mbano, Imo State, South East, Nigeria

Author(s):  
M. U. Elendu ◽  
A. A. Nwankwo ◽  
J. N. Egwurugwu ◽  
P. I. Ugwu ◽  
P. C. Ugwuezumba ◽  
...  

Aim: The Complete Blood Count (CBC) among hypertensive subjects in Isiala Mbano, Imo State, Nigeria West Africa were studied. Methodology: The American College of Cardiology/American Heart Association (2017) current definition of hypertension was used to ascertain, diagnoses and assigned eighty (80)hypertensive subjects after three different consecutive blood pressure check into tests groups. Other blood pressure measures such as pulse pressure and mean arterial pressure were calculated appropriately. Venous blood samples were collected with 5mls syringe and immediately emptied into EDTA container for complete blood count analysis. Results: The results showed increase in RBC count, HB, PCV and decrease in MCV among hypertensive subjects compared with normotensive subjects. It was statistically insignificant in all age groups. No changes were seen in MCHC and MCH. The results also, showed increase in PLTS count. The increase in PLTS count was statistically significant at P<0.05 and <0.001 among hypertensive age groups 36-65yrs and >66yrs respectively. Increase in PLTS count among 20-35yr age group was not significant. There were increase in WBC count among hypertensive subjects compared with normotensive subjects in all age groups. It was statistically significant at P<0.05 and <0.001 among hypertensive age groups 36-50yrs and >66yrs respectively. Neutrophil was increased in all age groups and was statistically significant at P<0.05 except 20-35yr age group. No changes were seen on lymphocytes, monocytes, eosinophils and basophils. Conclusion: Haematological parameters investigated could predict possible cardiovascular abnormalities such as hypertension.

2012 ◽  
Vol 25 (06) ◽  
pp. 460-465 ◽  
Author(s):  
I. Roquet ◽  
S. Hendrick ◽  
J. L. Carmalt

Summary Objective: Based on a systemic complete blood count and a synovial fluid sample, to develop a mathematical model enabling the approximation of corrected values for synovial fluid white blood cell (WBC) count, neutrophil percentage, and total protein concentration in samples of synovial fluid that were contaminated by blood. Methods: Peripheral venous blood and synovial fluid samples were obtained from ten horses. A pooled synovial fluid sample from each horse was separated into 2 mL aliquots, which were subsequently contaminated with a known percentage of autogenous blood (0 to 50% of the synovial fluid volume). A complete blood count, packed cell volume, total protein (TP) concentration, and differential cytological examination were performed in all the synovial fluid and venous blood samples. Regression analysis was used to generate a model to calculate non-contaminated synovial WBC count, TP concentration and synovial neutrophil percentage. Using a further five horses these models were applied in blinded fashion to contaminated synovial fluid samples. Calculated values were compared to non-contaminated measured values. Results: Model results for synovial WBC count and TP concentration were not significantly different from measured values. Calculated neutrophil percentage of synovial fluid WBC was a mean of 6.6% higher than measured values and was significantly different. There was no effect of the severity of contamination (as a percentage of volume) on the ability of the models to predict any of the outcome variables. Clinical significance: It is possible to calculate non-contaminated synovial fluid WBC and TP values, but not neutrophil percentage, from heavily contaminated samples. Further study would allow for improved prediction, validation and extrapolation to a wider horse population.


PEDIATRICS ◽  
1995 ◽  
Vol 95 (5) ◽  
pp. 623-627 ◽  
Author(s):  
Paul C. Young

Objective. To determine primary-care pediatricians' management of febrile infants and compare them with published practice guidelines. Design. Case scenarios were sent to 194 primary-care pediatricians in Utah, describing three febrile infants, ages 21 days, 60 days, and 20 months, corresponding to the three age groups: 0 to 28 days; 29 to 90 days, and 91 days to 36 months for which the guidelines suggest different strategies. Results. Ninety-four pediatricians responded (response rate, 48%). Compliance with the guidelines was 39% for the 21 day old, 9.6% for the 60 day old, and 75% for the 20 month old. No respondent followed the guidelines for all three infants. Performance of tests to determine if an infant was low risk varied from 3%, for a stool white cell examination in a febrile 2 month old with diarrhea, to 75% for a complete blood count in a 20 month old with a temperature of 40°C. Compliance did not differ between private and academic practitioners. Those in practice less than 5 years (n = 22) were more likely than those with more experience to follow the guidelines for the 21 day old but not the other two infants. Conclusion. Primary-care pediatricians in Utah manage febrile infants with fewer laboratory tests and less hospitalization than recent practice guidelines developed by an expert panel of academic specialists suggest.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Carlos Ricardo Maneck Malfatti ◽  
Leandro Tibiriçá Burgos ◽  
Alexandre Rieger ◽  
Cássio Luiz Rüdger ◽  
Janaína Angela Túrmina ◽  
...  

The essential hypertension has been associated with membrane cell damage. The aim of the present study is investigate the relationship between erythrocyte Na+,K+-ATPase and lipoperoxidation in prehypertensive patients compared to normotensive status. The present study involved the prehypertensive patients (systolic:136±7 mmHg; diastolic:86.8±6.3 mmHg;n=8) and healthy men with normal blood pressure (systolic:110±6.4 mmHg; diastolic:76.1±4.2 mmHg;n=8) who were matched for age (35±4years old). The venous blood samples of antecubital vein (5 mL) were collected into a tube containing sodium heparin as anticoagulant (1000 UI), and erythrocyte ghosts were prepared for quantifying Na+,K+-ATPase activity. The extent of the thiobarbituric acid reactive substances (TBARS) was determined in plasma. The statistical analysis was carried out by Student’st-test and Pearson’s correlation coefficient. AP<0.05was considered significant. The Na+,K+-ATPase activity was lower in prehypertensive patients compared with normotensive subjects (4.9 versus 8.0 nmol Pi/mg protein/min;P<0.05). The Na+,K+-ATPase activity correlated negatively with TBARS content (r=-0.6;P<0.05) and diastolic blood pressure (r=-0.84;P<0.05). The present study suggests that Na+,K+-ATPase activity reduction and elevation of the TBARS content may underlie the pathophysiological aspects linked to the prehypertensive status.


2004 ◽  
Vol 40 (4) ◽  
pp. 255-260 ◽  
Author(s):  
Nora S. Matthews ◽  
Raquel M. Brown ◽  
Kerry S. Barling ◽  
Sandra L. Lovering ◽  
Brent W. Herrig

A bolus of propofol was administered to 10 dogs (6 mg/kg intravenously [IV]) and 10 cats (10 mg/kg IV) on three consecutive days. The occurrence of apnea, heart and respiratory rates, blood pressure, time to movement, and changes in a complete blood count and biochemical profile were recorded. Apnea was not seen in the dogs but was seen in three cats. Slight increases in the number of Heinz bodies were seen in six cats, but the increases were not considered clinically significant. No apparent cumulative adverse effects were seen from a bolus of bisulfite-containing propofol, administered on three consecutive days.


2019 ◽  
Author(s):  
Nazarius Mbona Tumwesigye ◽  
Gerald Mutungi ◽  
Silver Bahendeka ◽  
Ronald Wesonga ◽  
Monica H. Swahn ◽  
...  

AbstractIntroductionUganda is experiencing a significant increase in the prevalence of non-communicable diseases including hypertension and obesity. Frequent alcohol use is also highly prevalent in Uganda and is a key risk factor for both hypertension and obesity. This study determines the trends of frequent alcohol consumption, hypertension and obesity across different age groups, and the extent to which alcohol consumption affects the two.MethodsThe data were extracted from the 2014 National Non-communicable Diseases Risk Factor Survey (N=3,987) conducted among adults aged 18 to 69 years. Hypertension was defined as systolic blood pressure ≥140mmHG or diastolic blood pressure ≥90. Obesity was defined as body mass index >30 kg/m2. Frequent alcohol consumption was defined as alcohol use 3 or more times a week. Multivariable log binomial regression analysis was carried out for each of the two outcome variables against age group and controlled for frequency of alcohol consumption and few other independent factors. Non-parametric tests were used to compare trends of prevalence ratios across age groups. Modified Poisson regression was use in few instances when the model failed to converge.ResultsThe results showed increasing trend in the prevalence of hypertension and frequent alcohol consumption but a declining trend for obesity along different age groups (p<0.01). Frequency of alcohol consumption did not significantly modify the age group-hypertension and age group-obesity relationships although the effect was significant with ungrouped age. There was significance in difference of fitted lines for hypertension prevalence ratios between frequent drinkers and mild drinkers and between abstainers and frequent drinkers. Alcohol consumption did not have any significant effect on obesity-age group relationship.ConclusionThe results call for more research to understand the effect of alcohol on the hypertension-age relationship, and the obesity-age relationship. Why prevalence ratios for hypertension decline among those who take alcohol most frequently is another issue that needs further research.


Author(s):  
G. Chethan Raj ◽  
Syam Sundar Junapudi

Background: The overall imbalance between unhealthy diet intake and physical activity leads to obesity which contributes to high blood pressure and high cholesterol. It is multi factorial disease and changes in the levels of blood pressure and blood lipids differ by age sex and race and are influenced by body fat and dietary patterns. These risk factors need to be monitored and evaluated in childhood and adolescents. So identifying and modifying the risk factors in early age reduces the incidence in adolescents and adult. Prevalence of hypertension varies across countries and states. The prevalence of hypertension in India is reported as ranging from 10 to 30.9%. The objective of the present study is to observe the prevalence hypertension among study population and to study contributing factors for hypertension among study population.Methods: A cross sectional study done on 100 adolescents and young adults of both sexes in the age group 17 to 25 years from 2 degree colleges randomly selected in Nizamabad city, Telangana, India.Results: In the present study population 52 were males and 48 were females, 22 students belongs to rural area and 78 belongs to urban area, pre-hypertension and hypertension was found 8% in both age groups. Overweight and obesity (>25) was found 7% in 17-19 age group and 9% in 20-25 age group. Pre-hypertension and hypertension was found among 10% of alcoholics.Conclusions: The result of our study concluded that there is increasing prevalence of hypertension with increase in age and is associated with overweight and obesity. 


2016 ◽  
Vol 20 (2) ◽  
pp. 200-209
Author(s):  
Michele Zimowski ◽  
Jack Moye ◽  
Bernard Dugoni ◽  
Melissa Heim Viox ◽  
Hildie Cohen ◽  
...  

AbstractObjectiveThe current study assessed whether home-based data collection by trained data collectors can produce high-quality physical measurement data in young children.DesignThe study assessed the quality of intra-examiner measurements of blood pressure, pulse rate and anthropometric dimensions using intra-examiner reliability and intra-examiner technical error of measurement (TEM).SettingNon-clinical, primarily private homes of National Children’s Study participants in twenty-two study locations across the USA.SubjectsChildren in four age groups: 5–7 months (n 91), 11–16 months (n 393), 23–28 months (n 1410) and 35–40 months (n 800).ResultsAbsolute TEM ranged in value from 0·09 to 16·21, varying widely by age group and measure, as expected. Relative TEM spanned from 0·27 to 13·71 across age groups and physical measures. Reliabilities for anthropometric measurements by age group and measure ranged from 0·46 to >0·99 with most exceeding 0·90, suggesting that the large majority of anthropometric measures can be collected in a home-based setting on young children by trained data collectors. Reliabilities for blood pressure and pulse rate measurements by age group ranged from 0·21 to 0·74, implying these are less reliably measured with young children when taken in the data collection context described here.ConclusionsReliability estimates >0·95 for weight, length, height, and thigh, waist and head circumference, and >0·90 for triceps and subscapular skinfolds, indicate that these measures can be collected in the field by trained data collectors without compromising data quality. These estimates can be used for interim evaluations of data collector training and measurement protocols.


2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
I. Arjun Rao ◽  
Adimoolam Chandrasekhar ◽  
Venugopal N. Pulamaghatta ◽  
Subal Das ◽  
Kaushik Bose

The present study investigated blood pressure levels as well as the prevalence of hypertension among adult Parengi Porja tribals of village Munchingput Mandalam, Visakhapatnam district, Andhra Pradesh, India. A cross-sectional study was used to collect data on systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse rate. A total of 137 adults (100 males and 37 females) were measured and classified into three age groups, that is, Gr-I: 23 to 32 years, Gr-II: 33 to 42 years, and Gr-III: ≥ 43 years. Negative significant sex difference in SBP among age group I (t=-2.409; P<0.05) was observed. Positive significant sex difference in DBP among age group I (t=2.545; P<0.05) was also observed. Significant age group difference was noticed for SBP (F=4.332; P<0.01) among males. Based on SBP, the prevalence of prehypertension and stage I hypertension in males was 25.0% and 5.0%, respectively. Similarly, in females the prevalence of prehypertension and stage I hypertension based on SBP was 32.4% and 5.4%, respectively. On the basis of DBP, the prevalence of stage I hypertension in males was 5.0%. Similarly, in females, the prevalence of stage I hypertension based on DBP was 5.4%. Our results suggest that females of this ethnic group were more prone to have prehypertension and stage I hypertension than males.


Open Medicine ◽  
2010 ◽  
Vol 5 (4) ◽  
pp. 486-494
Author(s):  
Adam Buciński ◽  
Jerzy Romaszko ◽  
Ryszard Targoński ◽  
Leszek Cichowski ◽  
Ewa Romaszko ◽  
...  

AbstractThe study is a retrospective analysis of data obtained from a cardiovascular disease prevention program financed by the National Health Fund (Poland). The aim of the study was to evaluate the population to demonstrate the prevalence of favourable and unfavourable lipid parameters and blood pressure values depending on age and BMI. A total of 2,616 subjects were included in the study (811 men and 1805 women aged between 35 and 55 years of age) who perceived themselves as completely healthy individuals and in whom no cardiovascular disease or diabetes mellitus had been diagnosed. We evaluated blood pressure values, body weight, height, BMI, fasting glucose, total cholesterol, triglycerides, HDL and LDL in the serum of venous blood. The above-mentioned parameters were compared in women and men depending on BMI and age. It was demonstrated that the epidemiological situation of women in the analysed age group, regardless of the studied parameter and method of its evaluation, is much more favourable than that of men. We have demonstrated that evaluation of the analysed lipid parameters and blood pressure should be performed with consideration to gender and age. Otherwise conclusions may be obtained which are not satisfied by 75-95% of the population in a given age group. Obesity was highlighted as a factor triggering further lipid disturbances and blood pressure increase.


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