scholarly journals A Mini-review: Silver Nanoparticles (AgNPs) as Antimicrobial in Magical Socks

Author(s):  
Lubna Abdulazeem ◽  
Yusor Fadhil Alasadi ◽  
Yasir Haider Al-Mawlah ◽  
Ameer M. Hadi

Silver nanoparticles vary in size from 1 to 100 nm. These have unique properties that assists in molecular diagnostics, therapies, and devices used in many medical procedures. The most popular methods for making silver nanoparticles are physical and chemical approaches. Chemical and physical methods are troublesome because synthesis is expensive. The biological approach is a feasible alternative one. The major biological processes involved are bacteria, fungi, and plant extracts. Silver nanoparticles are mainly used in diagnostic and therapeutic applications in medicine. Their medical uses rely on the antimicrobial property, while the anti-inflammatory property has its own range of applications. Silver nanoparticles are used in a number of medical therapies and instruments, as well as in a variety of biological sciences. This article focuses on chemical and biological techniques for synthesizing AgNPs, which will subsequently be utilized to coat socks materials, testing antimicrobial activity and comparing the ability of these coated fabrics to minimize infections.

Author(s):  
K.K. Gupta ◽  
Neha Kumari ◽  
Neha Sinha ◽  
Akruti Gupta

Biogenic synthesis of silver nanoparticles synthesized from Hymenocallis species (Spider Lilly) leaf extract was subjected for investigation of its antimicrobial property against four bacterial species (E. coli, Salmonella sp., Streptococcus sp. & Staphylococcus sp.). The results revealed that synthesized nanoparticles solution very much justify the color change property from initial light yellow to final reddish brown during the synthesis producing a characteristics absorption peak in the range of 434-466 nm. As antimicrobial agents, their efficacy was evaluated by analysis of variance in between the species and among the different concentration of AgNPs solution, which clearly showed that there was significant variation in the antibiotic property between the four different concentrations of AgNPs solution and also among four different species of bacteria taken under studies. However, silver nanoparticles solution of 1: 9 and 1:4 were proved comparatively more efficient as antimicrobial agents against four species of bacteria.


2021 ◽  
pp. 0958305X2198988
Author(s):  
Nur Syakirah Rabiha Rosman ◽  
Noor Aniza Harun ◽  
Izwandy Idris ◽  
Wan Iryani Wan Ismail

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.


Geofluids ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Máté Osvald ◽  
Gergely Maróti ◽  
Bernadett Pap ◽  
János Szanyi

Reinjection of heat-depleted thermal water has long been in the center of scientific interest in Hungary regarding around 1000 operating thermal wells. While the physical and chemical aspects of reinjection have partly been answered in the past years, the effects of biological processes are still less known. We carried out our investigations in the surface elements of the Hódmezővásárhely geothermal system which is one of the oldest operating geothermal systems in Hungary. About one-third of the used geothermal water has been reinjected since 1998 by two reinjection wells at the end of the thermal loops. During the operation, plugging of the surface system was experienced within a few-day-long period, due to biological processes. The goal of our research was to find the dominant species of the microbial flora and to make a proposal to avoid further bacterial problems. We found that the reinjected, therefore the produced, water’s chemical oxygen demand, phenol index, and BTEX composition basically determine the appearing flora on the surface. When the concentration of these compounds in the thermal water is significant and residence time is long enough in the buffer tank, certain bacteria can be much more dominant than others, thus able to form a biofilm which plugs the surface equipment much more than it is expected.


2017 ◽  
Vol 14 (3) ◽  
Author(s):  
Gláucia Oliveira da Silva

Abstract My objective is to discuss the persistence of the notion of natural selection in the biological sciences, exploring the fact that: (1) this notion, just like the term culture in anthropology, is historically an inaugural concept in its particular scientific field, and, insofar as both possess a value of heuristic delimitation, both thus came to be considered as explanatory concepts, although today they may be more widely accepted as descriptive in kind; (2) this persistence seems to be equally linked to the fact that the term combines randomness and teleology, but without foregrounding the inherent contradiction; (3) the anthropomorphic metaphors generally used in the description of biological processes, by attributing intentionality to beings lacking in self-determination, presume the existence of a nature defined by processes oriented towards precise ends, endorsing the finalism that, I believe, underlies the idea of natural selection; (4) and, finally, I think that ‘culture’ and ‘natural selection’ correspond to disciplinary labels - for social anthropology and biology respectively - that arose in Victorian Britain, as defined by the Great Divide, but they no longer have explanatory power.


2021 ◽  
Vol 09 ◽  
Author(s):  
Sarvat Zafar ◽  
Aiman Zafar ◽  
Fakhra Jabeen ◽  
Miad Ali Siddiq

: Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors, like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particles exhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulant and catalytic properties because of their unique dimensions with large surface area, chemical stability and higher binding density for the accumulation of various bio-constituents on their surfaces. Biological approaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easy and single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physical and chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesis has drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy to scale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaboration of nanomaterials with bio-green approaches could extend the utilization of biological and cytological properties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, and their potential biomedical applications have also been reviewed.


2013 ◽  
Vol 756 ◽  
pp. 106-111 ◽  
Author(s):  
Selvaraj Arokiyaraj ◽  
Udaya Prakash Nyayiru Kannaian ◽  
Vijay Elakkya ◽  
T. Kamala ◽  
S. Bhuvaneswari ◽  
...  

The aim of the present study is to synthesize silver nanoparticles, using an aqueous floral extract of common Lotus, i.e Nelumbo nucifera. The synthesized nanoparticles were characterized using UV, TEM, EDX, AFM & XRD. The synthesized AgNPs were confirmed due to the colour change from colourless to reddish brown just after the addition of the aqueous floral extract of Nelumbo nucifera. The UV results of AgNPs showed the excitation of surface Plasmon resonance band at 427 nm. TEM results showed that the synthesized AgNPs were uniformed; monodispersed,spherical in shape and the particle size were found to be 77.81 ± 3.54 nm. EDX spectrum of AgNPs confirms strong signals from Ag (64%) and other elements such as C, O and Cl. The morphology of the synthesized AgNPs by AFM analysis resembled the TEM micrograph. The crystalline nature of the AgNPs was confirmed by XRD. The present study concludes that the aqueous floral extract of Nelumbo nucifera could be used as an effective reducing agent for the synthesis of AgNP. The green synthesis ofsilver nanoparticles is non-toxic and cost-effective and thus remains to be an alternative method to other physical and chemical reduction methods.


Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2268 ◽  
Author(s):  
Garima Sharma ◽  
Ju-Suk Nam ◽  
Ashish Sharma ◽  
Sang-Soo Lee

Coptidis rhizome contains several alkaloids that are bioactive agents of therapeutic value. We propose an eco-friendly method to synthesize biocompatible silver nanoparticles (AgNPs) using the aqueous extract of Coptidis rhizome. Silver ions were reduced to AgNPs using the aqueous extract of Coptidis rhizome, indicating that Coptidis rhizome can be used for the biosynthesis of AgNPs. The time and the concentration required for conversion of silver ions into AgNPs was optimized using UV-absorbance spectroscopy and inductively coupled plasma spectroscopy (ICP). Biosynthesized AgNPs showed a distinct UV-Visible absorption peak at 420 nm. ICP analysis showed that the time required for the completion of biosynthesis was around 20 min. Microscopic images showed that nanoparticles synthesized were of spherical shape and the average diameter of biosynthesized AgNPs was less than 30 nm. XRD analysis also confirmed the size of AgNps and revealed their crystalline nature. The interaction of AgNPs with phytochemicals present in Coptidis rhizome extract was observed in FTIR analysis. The antimicrobial property of AgNPs was evaluated using turbidity measurements. Coptidis rhizome-mediated biosynthesized AgNPs showed significant anti-bacterial activities against Escherichia coli and Staphylococcus aureus that are commonly involved in various types of infections, indicating their potential as an effective anti-bacterial agent.


2018 ◽  
Vol 917 ◽  
pp. 145-151 ◽  
Author(s):  
Nur Syazana Jalani ◽  
Sharifah Zati-Hanani ◽  
Yi Peng Teoh ◽  
Rozaini Abdullah

Recently, interest in plant-mediated synthesis of the silver nanoparticles (AgNPs) is growing among researchers and till now the potential of different plants is still further explored to synthesize nanoparticles. Conventionally, AgNPs are synthesized using chemical and physical methods. However, these methods involve use of toxic and hazardous chemicals which are harmful to health and environment. Therefore, plant-mediated synthesis has been used as environmental friendly alternative to overcome the limitation of conventional methods. The bioactive compounds in plant acts as natural reducing and stabilizing agents which help to increase the rate of synthesis and stabilization of synthesized nanoparticles. Besides, the nanoparticles synthesized using plants are reported to be more stable and the rate of synthesis is much faster compared to other methods. This review focuses on the biosynthesis of AgNPs using plant as natural source plant and the effect of reaction conditions are summarised and discussed.


2019 ◽  
Vol 25 (24) ◽  
pp. 2650-2660 ◽  
Author(s):  
Rajasree Shanmuganathan ◽  
Indira Karuppusamy ◽  
Muthupandian Saravanan ◽  
Harshiny Muthukumar ◽  
Kumar Ponnuchamy ◽  
...  

Generally, silver is considered as a noble metal used for treating burn wound infections, open wounds and cuts. However, the emerging nanotechnology has made a remarkable impact by converting metallic silver into silver nanoparticles (AgNPs) for better applications. The advancement in technology has improved the synthesis of NPs using biological method instead of physical and chemical methods. Nonetheless, synthesizing AgNPs using biological sources is ecofriendly and cost effective. Till date, AgNPs are widely used as antibacterial agents; therefore, a novel idea is needed for the successful use of AgNPs as therapeutic agents to uncertain diseases and infections. In biomedicine, AgNPs possess significant advantages due to their physical and chemical versatility. Indeed, the toxicity concerns regarding AgNPs have created the need for non-toxic and ecofriendly approaches to produce AgNPs. The applications of AgNPs in nanogels, nanosolutions, silver based dressings and coating over medical devices are under progress. Still, an improvised version of AgNPs for extended applications in an ecofriendly manner is the need of the hour. Therefore, the present review emphasizes the synthesis methods, modes of action under dissipative conditions and the various biomedical applications of AgNPs in detail.


2013 ◽  
Vol 394 (1) ◽  
pp. 113-123 ◽  
Author(s):  
Radoslaw Szmyd ◽  
Anna Grazyna Goralczyk ◽  
Lukasz Skalniak ◽  
Agnieszka Cierniak ◽  
Barbara Lipert ◽  
...  

Abstract Silver nanoparticles (AgNPs) have many biological applications in biomedicine, biotechnology and other life sciences. Depending on the size, shape and the type of carrier, AgNPs demonstrate different physical and chemical properties. AgNPs have strong antimicrobial, antiviral and antifungal activity, thus they are used extensively in a range of medical settings, particularly in wound dressings but also in cosmetics. This study was undertaken to examine the potential toxic effects of 15 nm polyvinylpyrrolidone-coated AgNPs on primary normal human epidermal keratinocytes (NHEK). Cells were treated with different concentrations of AgNPs and then cell viability, metabolic activity and other biological and biochemical aspects of keratinocytes functioning were studied. We observed that AgNPs decrease keratinocyte viability, metabolism and also proliferatory and migratory potential of these cells. Moreover, longer exposure resulted in activation of caspase 3/7 and DNA damage. Our studies show for the first time, that AgNPs may present possible danger for primary keratinocytes, concerning activation of genotoxic and cytotoxic processes depending on the concentration.


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