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Author(s):  
Deepti Negi ◽  
Anoop Kumar Singh ◽  
Vipin Kumar ◽  
Shweta G Shukla

Darunak is a Vata –Kaphaj Vyadhi. Sushruta mentioned it under Kshudra roga. Chakradatta has mentioned application of Maltyadi Tail (Jaati, Karveer, Chitrak, Karanj, base oil- Tila Tail) in the treatment of Darunak. Aggravation of Kapha and Vata in Darunak causes, itching, falling of hair, loss of sensation, dryness and small cracks of the skin of the scalp. Several factors increase the risk of developing dandruff, including a person’s age, the weather, stress levels, fungus, medical conditions, and choice of hair products. Oiling is the best way to get a healthy scalp. Aim and objective: To evaluate efficacy of Maltyadi Tail in the management of Darunak w.s.r to dandruff. Materials and Methods: In this clinical study total 46 Patients of Darunak were registered out of which 3 patients left the treatment; remaining 43 patients were divided into 2 groups. 23 patients were treated in group A (test drug- Maltyadi Tail) and 20 patients were treated in group B (control drug- Tila Tail) for 30 days. The effect of therapy was assessed on the basis of changes in grading score. Result: In clinical study, All the cardinal and associate symptoms except Raag, Daah, Ruja were statistically significant improved after the complete course of test drug (Maltyadi Tail). Effect of Group A reduced Kesha Bhoomi Rookshta by 92.68%, Kandu by 100%, Keshbhoomi Prapatan by 92.68% and Keshchyuti by 87.50% which was statistically highly significant. Conclusion: The study revealed that test drug (Maltyadi tail) is more effective in Darunak /dandruff compare to control drug (Tila Tail).


2021 ◽  
Vol 14 (33) ◽  
pp. e16443
Author(s):  
Stefane Rodrigues Colman ◽  
Gregory da Silva Balthazar

This article focuses on a possible permeability between feminist experience and evangelical Neo-Pentecostal experience. Through a focus group approach, we problematize the intersection between the pulsating gender pedagogy in prosperity theology and the lines of force of two feminist premises, which was resignified by a neoliberal rationality: gender equality and female empowerment. Therefore, we defend that the sayings of young evangelicals allow us to suggest the existence of a post-feminist heterotopia: spaces, certainly not full of neoliberal gender discourse ruptures, despite of that, still give rise to small cracks that from the very heart of normativity allow these evangelical young women to create other subjective possibilities for themselves.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Wang Liu ◽  
Xiao Li ◽  
Fengjiao Wu

Considering the problems of fuzzy repair and low pixel similarity matching in the repair of existing tomb murals, we propose a novel tomb mural repair algorithm based on sequential similarity detection in this paper. First, we determine the gradient value of tomb mural through second-order Gaussian Laplace operator in LOG edge detection and then reduce the noise in the edge of tomb mural to process a smooth edge of tomb mural. Further, we set the mathematical model to obtain the edge features of tomb murals. To calculate the average gray level of foreground and background under a specific threshold, we use the maximum interclass variance method, which considers the influence of small cracks on the edge of tomb murals and separates the cracks through a connected domain labelling algorithm and open and close operations to complete the edge threshold segmentation. In addition, we use the priority calculation function to determine the damaged tomb mural area, calculate the gradient factor of edge information, obtain the information entropy of different angles, determine the priority of tomb mural image repair, detect the similarity of tomb mural repair pixels with the help of sequential similarity, and complete the tomb mural repair. Experimental results show that our model can effectively repair the edges of the tomb murals and can achieve a high pixel similarity matching degree.


2021 ◽  
pp. 30-33
Author(s):  
Елена Владимировна Калмыкова ◽  
Ольга Владимировна Калмыкова

В данной статье предложена усовершенствованная технология производства диетического десерта - безе на основе растительного белка нута (аквафаба) - в качестве замены животных белков. Аквафаба - это отвар из семян бобовых культур, таких как нут, фасоль, горох. В процессе отваривания бобовых крахмалы в плодах (семенах) частично начинают превращаться в желе. Это способствует тому, что растворимые частицы крахмалов переходят в жидкость, в которой они варятся. Чем выше температура, давление при варке, чем дольше время отваривания, тем большее количество желеобразующих веществ перемещается из плодов в отвар. Разработаны рецептура и элементы технологии производства безе функциональной направленности. В качестве ингредиентов для безе на основе растительного белка использовали аквафабу, сахар, лимонный сок, соль. Поверхность готового воздушного изделия была светло-кремового цвета, хрупкая, с твердой корочкой и рифлеными краями, с шероховатостью и характерными небольшими трещинами, изделия были хорошо пропечены, без следов подгорелости. Вкус и запах, свойственные данному наименованию, без посторонних привкусов и запахов. Влажность изделия составляла 3,5 %. Установлено, что по пищевой ценности разработанные изделия превосходят традиционную пастилу. В современном мире большое внимание уделяется правильному питанию и образу жизни. Поэтому необходимо рекомендовать продукты, которые положительно влияют на организм человека. В связи с этим нужно изучить возможности производства безе, содержащего полезные биологически активные вещества и функциональные ингредиенты. Экспериментально полученный состав безе с заменой животного белка на растительный рекомендуется для использования не только всем группам населения, но и людям, у которых ранее был запрет на использование таких продуктов. This article proposes an improved technology for the production of a dietary dessert - meringue based on vegetable protein chickpea (aquafaba) as a replacement for animal proteins. Aquafaba is a decoction of the seeds of legumes such as chick-peas, beans, peas. In the process of boiling the legumes, the starches in the fruits (seeds) partially begin to turn into jelly. This helps the soluble starch particles pass into the liquid in which they are cooked. The higher the temperature, the pressure during cooking, the longer the boiling time, the more jellyforming substances move from the fruit to the broth. The formulation and elements of the production technology for the production of functional meringue have been developed. Aquafaba, sugar, lemon juice, and salt were used as ingredients for a vegetable proteinbased meringue. The surface of the finished airy product was light creamcolored, brittle with a hard crust and corrugated edges, with roughness and characteristic small cracks, well baked, without traces of burnt. Taste and smell are characteristic of this product name, without foreign tastes and odors. The moisture content of the product was 3.5 %. It was found that the developed products are superior in nutritional value to traditional marshmallows. In the modern world, great attention is paid to proper nutrition and lifestyle. Therefore, it is necessary to recommend products that have a positive effect on the human body. In this regard, it is necessary to study the possibility of producing meringues containing useful biologically active substances and functional ingredients. The experimentally obtained meringue composition with the replacement of animal protein with vegetable protein is recommended for use not only for all groups of the population, but also for people who previously had a ban on the use of such products.


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257873
Author(s):  
Shao-Chin Chiang ◽  
Mandy Shen ◽  
Chen-Chia Lin ◽  
Hui-Ping Chang

Closed-system drug transfer devices (CSTDs) are used to prevent occupational exposure to hazardous drugs in health care providers. They are considered Class II medical devices by the US FDA and are cleared but not approved before marketing. While compatibility tests are conducted by CSTD manufacturers, the procuring institution needs to consider performing its own studies before buying these devices. Herein we tested the compatibility of the components of the Needleless® DualGuard CSTD system (vial access clips, vial access spikes, and administration adaptors) with 10 antineoplastic drugs, under simulated clinical conditions, including compounding and administration, and examined drug potency maintenance, plasticizer migration, and device functionality. All drugs maintained potency within 5%. Diisononyl phthalate leakage was observed from the administration adaptors for paclitaxel and concentrated etoposide solution. In addition, white particles were discovered in CSTDs storing busulfan solution and small cracks were observed on devices which stored melphalan. Thus, it was concluded that even in simulated clinical conditions, instead of extreme conditions, there are still concerns regarding the efficacy and safety of CSTD components. The methodology may be used to implement and detect possible interactions between antineoplastic agents and CSTD components before procurement.


Author(s):  
Viktoriia Kulinich ◽  
Viktor Vorobyov ◽  
Larysa Vorobyova ◽  
Iryna Peeva

A method for estimating crack formation in a solid is proposed. The necessity the crack formation dynamics investigation is substantiated. Based on the Rebinder effect, a method for controlling the cracking nature using surfactants is proposed. The destruction by impact and explosion of samples pre-treated with water and surfactant is considered. It is established that pre-treatment of glass plates with surfactant solution shows a more uniform cracks distribution on impact, which may be the basis for the assumption that the surfactants use in blasting will significantly improve the crushing quality and reduce the oversized fractions yield. When examining the samples, which were saturated with surfactant solution, it is seen that the cracks system only increased after the explosion, small cracks appeared, which connect large ones. In the case of water use, we also see an increase in cracking, but it is not as intense and uniform as in the case of surfactants previous use. This result also confirms the fact that the pre-saturation of the medium with a surfactant solution before the pulse loads contributes to a more uniform crushing in the future and provides a basis for experiments on three-dimensional models in this direction.


2021 ◽  
Author(s):  
Hala H. A. Mahmoud ◽  
Mohamed H. A. Kalaba ◽  
Gamal M.E. El-Sherbiny ◽  
Abdelzaher E. A. Mostafa ◽  
Mohamed E. A. Ouf ◽  
...  

Abstract The small cracks in concrete constructions are inevitable due to deterioration during their service life throughout different load combination factors. In this study, we aimed to isolate, identify, and construct a bacterial consortium able to heal small cracks of concrete and enhance the different properties of concrete. Six isolates of bacillus, endospore-forming bacteria were isolated. There are only three isolates out of the six coded as NW-1, MK and NW-9 were showed the ability to produce urease enzyme and able to grow at 60°C with optimum growth at a temperature of 40°C. These isolates were survived in high pH, where isolate NW-1 was tolerated pH up to 11 with optimum growth at 10 while the isolates NW-9 and MK showed growth at pH 12 with an ideal growth at 10. CaCO3 production was observed by the three bacterial isolates whether in pure or mixed cultures (bacterial consortium) but the consortium consisting of MK and NW-9 was significantly the highest in productivity among them. Therefore, these two isolates were identified using 16s as Bacillus flexus MK-FYT-3 and Bacillus haynesii MK-NW-9 and deposited to GenBank under accession numbers MN965692 and MN965693 respectively. The effect of bacteria on some properties of concrete was studied, and the results showed that the compressive and tensile strengths of bio-concrete specimens were significantly increased by 31.29, 29 % after 7 days and 36.3, 39 % after 28 days of curing compared to control specimens. The results of permeability indicated that the bio-concrete specimens significantly showed less permeability than the control specimens by 21.1, 23.1% after 7 and 28 of curing, respectively. To determine the concrete density, Ultrasonic Pulse Velocity (UPV) test was performed, and the bio-concrete specimens gave higher values ​​than control specimens by 26 and 20% after curing for 7 and 28 days, respectively. Also, surface healing of concrete was observed visually, the bio-concrete showed white precipitates around and inside the cracks after 7 days, which led to almost complete sealing of concrete after 28 days of curing, while the control samples were showed only very slight deposits on the surface and away from the cracks. The micro-analysis of concrete samples using SEM and XRD were done. It was found that the bio-concrete specimens showed crystalline precipitate with different shapes under SEM, while no such deposits appeared in the control specimens. On the other hand, the XRD profile was explained the characteristic peaks of calcium carbonate in both the bio-concrete and the control specimens, but the peak intensity was higher in the bio-concrete than the control specimens. This reflects the effectiveness of bacterial consortium in repairing and preventing the concrete cracks from spreading in addition to improving the various properties of concrete leading to increasing its life and sustainability.


Sensors ◽  
2021 ◽  
Vol 21 (12) ◽  
pp. 3967
Author(s):  
Dragos A. Poiana ◽  
Jose A. Garcia-Souto ◽  
Xiaoyi Bao

The broad-frequency response and nanometer-range displacements of ultrasound detection are essential for the characterization of small cracks, structural health monitoring and non-destructive evaluation. Those perturbations are generated at sub-nano-strain to nano-strain levels. This corresponds to the sub-nm level and, therefore, to about 0.1% of wavelength change at 1550 nm, making it difficult to detect them by conventional interferometric techniques. In this paper, we propose a demodulation system to read the random fiber grating spectrum using a self-heterodyne acousto-optic frequency comb. The system uses a self-heterodyne approach to extract phase and amplitude modulated signals to detect surface acoustic waves with sub-nanometer amplitudes in the frequency domain. The method can detect acoustic frequencies of 1 MHz and the associated displacement. The system is calibrated via phase detection with a heterodyne interferometer, which has a limited frequency response of up to 200 kHz. The goal is to achieve sub-nanometer strain detection at MHz frequency with random fiber gratings.


2021 ◽  
Vol 8 (2) ◽  
pp. 20218206
Author(s):  
E. G. Kalinina ◽  
D. S. Rusakova ◽  
E. Yu. Pikalova

The electrophoretic deposition (EPD) of coatings and bulk compacts in a wide range of thicknesses (from 23 to 1800 μm) from stable suspensions of a magnesium-doped aluminum oxide nanopowder with subsequent sintering of samples into dense ceramics was studied. The initial nanopowder was obtained by the method of electric explosion of an Al-Mg alloy wire with a Mg content of 1.3 wt. %. The study of the dispersion composition, kinetics of deaggregation under the ultrasonic treatment and zeta potential in the nanopowder-based suspensions was carried out. It was shown that a nearly linear increase in the deposited mass and thickness of EPD deposits occurred at a constant voltage of 20 V and an average deposition current of approximately 40 μA when the deposition time was varied from 1 to 180 min. Drying of the coatings with a thickness of less than 35 μm led to the formation of a net of small cracks, while drying of the bulk compacts with a thickness of more than 1 mm occurred without cracking. The ceramic bulk sample with a thickness of 1.2 mm and the density of 98.7% TD was successfully obtained by sintering at 1650 °C for 4 h. It was characterized by a dense grain structure with an average grain size of 5 μm and the presence of a small number of closed pores less than 1 μm in size. Sintering of ceramics was revealed to be accompanied by the formation of a MgAl2O4 crystalline spinel phase, localized mainly at grain boundaries.


Author(s):  
Péter Szalva ◽  
Imre Orbulov

AlSi9Cu3(Fe) vacuum-assisted high pressure die cast (VPDC) specimens were investigated by experimental fatigue test and fracture mechanics approach. The aims of the investigations were (i) to evaluate the fracture resistance and (ii) to indirectly determine the threshold stress intensity value (ΔKth) of casting alloy in uniaxial tension. The specimens were sorted into two groups: specimens with different size (0.01-0.40 mm2) natural defects, and specimens an additional artificial blind hole. The fatigue strength region was tested at R=-1 stress ratio to 107 number of cycles to fracture. The fracture mechanics approach was applied to study the behavior of the small cracks by Kitagawa diagram, the defect size was taken into account by the Murakami’s (√area) parameter. The fatigue strength values were 104.7 MPa for smooth specimen, 92.7 MPa for specimen with D0.3 artificial hole, and 87.2 MPa for specimen with D0.6 artificial hole at the prescribed cycles, respectively.


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