Diet and Dementia: A Prospective Study

Whether dietary and nutrition and dietary patterns are associated with the development of dementia is an interesting research question. Participants of a longitudinal cohort study that included European adults who were middle to old aged at baseline and who had not been diagnosed with dementia at baseline (2006–2010) and had not been diagnosed with dementia or died within 5 years after baseline were followed up (until 2018) and analyzed. Associations between intake frequency of each food class measured by the food-frequency questionnaire at baseline and incident dementia 5 years after baseline were analyzed after correcting for confounding variables. A total of approximately 340,000 participants and 900 cases were included in the analysis for each food class. Cox proportional hazard models with self-reported intake level of each food category divided into four mostly equally divided categorical variables revealed a high intake of bread, moderate total meat and total fish intake and low vegetable and fruit intake were thus associated with a small but significant decrease in the onset risk of dementia, while poultry and cereal were not. These findings are mostly inconsistent with the idea that Mediterranean diet is associated with lower risk of subsequent incident dementia.

Meat yield characteristics of different upgraded dwarf chicken under intensive management condition

The study was conducted with attempts to determine the effects of autosomal dwarf (adw) gene introgression from Indigenous dwarf chicken (IDC) to White Leghorn (WLH) and Fayoumi (Fay) on growth and meat yield characteristics. Experiment was carried out at the Poultry Farm of Bangladesh Agricultural University (BAU), Mymensingh for a period of 28 months from March 2013 to June 2015 under intensive management condition. In this study, the di-allele crossing between WLH, Fay and IDC produced 4 up-graded chickens viz. IDC♂ × WLH♀, WLH♂ × IDC♀, IDC♂ × Fay♀ and Fay♂ × IDC♀. The up-graded F1 generations were mated intersex to access their productivity. The up-graded F1 generations were mated intersex to access their productivity. Pre-slaughter live weight of birds significantly (P<0.001) varied by genotype, sex and genotype × sex interaction. Percentage of thigh meat, drumstick meat, dark and total meat weights was significantly influenced by genotype. Although meat yield parameters of male birds in relation to live weight were found higher than their female birds, some parameters like breast meat, liver, giblet and total meat yield were found higher in female birds than that of male birds of all genotypes. However, meat yield parameters like percentage of thigh, drumstick and total meat yield were the highest in IDC♂ × Fay♀ and Fay♂ × IDC♀ and the lowest in IDC♂ × WLH♀. From the above findings, Fayoumi mediated dwarf genotypes showed better meat yield characteristics than Leghorn mediated dwarf genotypes.

Effect of different selenium sources and concentrations on glutathione peroxidase activity and cholesterol metabolism of beef cattle

The objective of this study was to investigate the effects of different Se sources and concentrations on glutathione forms and cholesterol metabolism in beef cattle. Sixty-three Nellore bulls (412 ± 19 kg BW; 24 months old) were randomly assigned to a completely randomized design in a 2×3 + 1 factorial arrangement (63 pens; one animal/pen) with two Se sources (sodium selenite, ING and Se-yeast, ORG), three concentrations (0.3, 0.9 and 2.7 mg supplemental Se/kg DM), and control treatment (without Se supplementation) fed for 90 days. Blood samples were collected on d 0, 28, 56, and 84. Muscle and liver samples were collected at harvest. Hepatic GSSG (P = 0.004), GSH/GSSG ratio (P = 0.030), and GSH-Px (P = 0.004) were affected by Se source x concentration interaction. Oxidized glutathione was higher in the ORG group vs. ING at concentration 2.7 mg supplemental Se/kg DM, but at 0.3 mg supplemental Se/kg DM the ING group was higher than ORG. The liver GSH-Px activity was higher in the ORG group vs. ING at concentration 0.9 and 2.7 mg supplemental Se/kg DM. The GSH/GSSG ratio was the highest in animals fed 0.3 mg supplemental Se/kg DM of ORG. Selenium liver concentration increased linearly with the supplemental Se concentration in the diet (y = 0.0583 + 0.4254x, R 2 = 0.92, P &lt; 0.0001), regardless of source. Total meat cholesterol was greater (P &lt; 0.001) in CON (control) vs. SUP (supplemented, regardless source) group. The muscle GSH-Px activity was higher (P &lt; 0.001) in SUP vs. CON and increased (P &lt; 0.004) with increasing supplemental Se concentrations. There was an increase on VLDL, glucose, and triglycerides in ORG vs. ING (P ≤ 0.035). In general, serum Se was higher (P &lt; 0.001) in SUP vs. CON and increased with increasing supplemental Se concentration. Lastly, the HMGCR concentration was lower (P = 0.002) in SUP (0.39 ng/mL) vs. CON (0.55 ng/mL). Selenium supplementation with different sources and concentrations has the potential to affect cholesterol metabolism by affecting GSH/GSSG ratio, GSH-Px, and the HMGCR.

Higher Meat Intake Is Associated with Higher Inflammatory Markers, Mostly Due to Adiposity: Results from UK Biobank

ABSTRACT Background High meat consumption might play a role in promoting low-grade systemic inflammation, but evidence is limited. Objectives We examined cross-sectional associations of habitual meat consumption with serum C-reactive protein (CRP) and total white blood cell count (WBCC) in British adults. Methods We included 403,886 men and women (aged 38–73 y) participating in the UK Biobank who provided information on meat intake (via touchscreen questionnaire) and a nonfasting blood sample at recruitment (2006–2010). For a subset of participants (∼5%), an additional blood sample was collected (median 4.4 y later). We used multivariable linear regression models to estimate associations of meat intake (total meat, unprocessed red meat, processed meat, and poultry) with logCRP and logWBCC. Results The difference in the serum CRP (mg/L) for each 50-g/d higher intake for total meat was 11.6% (95% CI: 11.1, 12.0%), for processed meat was 38.3% (95% CI: 36.0, 40.7%), for unprocessed red meat was 14.4% (95% CI: 13.6, 15.1%), and for poultry was 12.8% (95% CI: 12.0, 13.5%). The difference in the WBCC (×10–9L) for each 50 g/d higher intake of total meat was 1.5% (95% CI: 1.4, 1.6%), for processed meat was 6.5% (95% CI: 6.1, 6.9%), for unprocessed red meat was 1.6% (95% CI: 1.4, 1.7%), and for poultry was 1.6% (95% CI: 1.4, 1.7%). All associations were attenuated after adjustment for adiposity; by 67% with BMI (in kg/m2) and by 58% with waist circumference for total meat and CRP, and by 53% and 47%, respectively, for WBCC, although associations remained statistically significant. Findings of sensitivity analyses in 15,420 participants were similar prospectively, except there were no associations between unprocessed red meat and WBCC. Conclusions Higher meat consumption, particularly of processed meat, was positively associated with inflammatory markers in these British adults; however, the magnitudes of associations are small and predominantly due to higher adiposity.

A Model for Prediction of the Buffalo and Cattle male Calves' live Weight

The buffalo and cattle population in Egypt reached about 4.898,893 and 3,476,396 heads, respectively, in 2019. The buffalo and cattle meat production represented around 43% and 45% of the total meat production in Egypt, respectively, and the average carcass weight of buffalo and cattle reached 318 kg and 336Kg in 2019. About 50% of livestock numbers are slaughtered off-slaughter houses due to a shortage in the capacity of slaughterhouses and other financial and administrative reasons. The conducted field survey of this study showed that the majority of Egyptian livestock markets lack live weight scales, and if available, they are expensive and frightening for the animals. Therefore, numerous feedlot enterprises hire an agent who can visually forecast the expected live weight of the exhibited feeder calves for sale in the market at a high charge. Most of the models to predict the weight of live cattle-bulls knowing the chest circumference were lacking such models for buffalo-bulls and were linear models that fit only limited periods of cattle-fattening. The sample survey included 500 buffalo males and 340 cattle males of different live weights from 14 villages in 4 provinces in the Nile Delta. The data were used to estimate the best-fitted model for Egyptian livestock. This study showed that the best-fitted model was curved linear. It was a quadratic form. For empirical application, the study designed a table to predict the live weight of buffalo and cattle males at a range of 100-200 cm chest circumference. The results showed that a 1% increase in the chest circumference was associated with a 2.4% and 2.8% increase in the buffalo and cattle male's circumference, which implicitly reflects higher live weight gain of cattle than buffalo males and better meat quality. Therefore, the farm price of cattle feeder males surpassed the buffalo by $1000.

Effect of Incorporating Early Feather Restriction Gene (KS) From Native Chicken to Purebred Chicken

Fast growing chicken suffers more in a hot humid condition than a slow growing one. The slow feathering affects the insulation mechanism of the chicken, thus enhance birds ability to dissipate heat during heat stress to a greater extent. As a consequence, slow feathered birds are more adaptive to hot humid environmental conditions. This study was undertaken to investigate the effect of incorporating early feather restriction gene (KS) in exotic population. A total of 34 slow feathered (SF) native chicks with KS gene of 28-day-old were collected from different villages and markets and were reared up to sexual maturity. After attaining sexual maturity, 2 males and 8 females of SF native chicken were randomly chosen to make a di-allelic cross with rapid feathered (RF) Rhode Island Red (RIR) and Fayoumi (FY). The crossbred progeny of each cross were reared up to 105 days to assess growth, survivability, heat tolerance and carcass yield under hot humid Bangladeshi condition. The collected data were arranged in a 3(genotype)×2(feather pattern)×9(age) factorial experiment in a Completely Randomized Design (CRD) and analyzed by SAS. Among genotypes, the highest survivability was obtained in Desi×Fayoumi (96.7%) and in SF chicks (96.1%) and the lowest in Desi×RIR (91.5%) and in RF chicks (90.5%). The SF chicks exhibited an average 8% heavier live weight than that of their RF counterparts. The cloacal temperature varied among genotypes and between feathering patterns (FP); being highest in Desi×RIR (430C) and in RF chicks (41.60C) and lowest in RIR×Desi (400C) and in SF chicks (41.40C). In case of Desi×RIR, RIR×Desi and Desi×Fayoumi, cloacal temperature increased linearly by 0.047, 0.044 and 0.0320C for each gram of live weight increase. Further, the cloacal temperature increased linearly by 0.036 and 0.0440C for the increase of each gram of live weight gain in case of RF and SF chicks, respectively. There was no significant (P>0.05) difference of dressing percentage for the effect of either genotype or FP (55.4% for SF vs. 46.6% for RF birds). Genotype and FP had significant effects (P<0.05; P<0.01) on total meat yield; being highest in Desi×RIR (24.6%) and in SF birds (26.2%) and lowest in Desi×Fayoumi (21.4%) and in RF birds (20.6%). Breast meat yield of SF birds (9.2%) was significantly (P<0.01) higher than that of RF birds (7.1%). The highest thigh meat yield was obtained in Desi×RIR (7.6%) and in SF birds (8.3%) and the lowest in Desi×Fayoumi (6.7%) and in RF counterparts (6.0%). The highest drumstick meat yield was obtained in RIR×Desi (5.6%) and in SF birds (5.9%) and the lowest in Desi×Fayoumi (5.0%) and in RF birds (4.8%). Genotype and FP had significant interaction effect on total meat yield as well as fractional meat yields. The study revealed that incorporation of ‘Ks’ gene in the exotic one by crossing with native chicken and rearing under hot humid environment may be a means of improving growth, survivability, heat tolerance and carcass yield.

Comparative Analysis of Meat Bone Meal and Meat Bone Combustion Using the Life Cycle Assessment Method

LCA analysis with 16 impact categories was used for the comparison of two developed combustion technologies: Scenario I—the combustion of meat bone meal produced from all types of meat waste; Scenario II—the combustion of meat bones from the production of meat products. The key hotspots determined were electricity and natural gas consumption, covering as much as 98.2% of the total influence on the environment in Scenario I and 99.3% in Scenario II. Without taking into account the environmental burdens avoided, the LCA analysis showed that Scenario I was assessed to have 71.2% less environmental impact. The avoided burdens approach changed the relationship between the two scenarios. The absolute value score for the overall environmental impact shows that Scenario II can be more environmentally beneficial than Scenario I; however, Scenario I allowed the elimination of all types of Polish meat waste, and Scenario II could only be carried out in meat production units for the elimination of meat bone waste and by-products from meat processing (i.e., 23% of the total meat waste produced in Poland).

US and UK Consumer Adoption of Cultivated Meat: A Segmentation Study

Despite growing evidence of the environmental and public health threats posed by today’s intensive animal production, consumers in the west remain largely attached to meat. Cultivated meat offers a way to grow meat directly from cells, circumventing these issues as well as the use of animals altogether. The aim of this study was to assess the overall consumer markets and a range of preferences around cultivated meat in the US and the UK relating to nomenclature, genetic modification, health enhancements, and other features. To this end, we recruited large representative samples to participate in an online survey about cultivated meat, and subsequently analyzed segments (a) in the early majority population (guided by the Diffusion of Innovations Model), (b) by generation, and (c) in the general population. Our findings showed a high level of openness (80%) in both the US and UK populations, with 40% somewhat or moderately likely to try and 40% highly likely to try. Younger generations had the greatest openness: 88% of Gen Z, 85% of Millennials, 77% of Gen X, and 72% of Baby Boomers were at least somewhat open to trying cultivated meat. All segments envisioned cultivated meat to be nearly half of their total meat intake. Findings show that consumers prefer the terms ‘cultured’ and ‘cultivated’ over ‘cell-based’ and ‘cell-cultured’ for use in a social context and on packages, even though they perceive these terms as less descriptive. The most important on-package label was one indicating government assurances, and participants preferred non-GM products over GM products. We also found that US consumers prefer nutritionally superior meat over nutritionally equivalent meat. We discuss implications for product development, messaging, and understanding the likely adoption path of this food innovation.

The Association of Meat Intake With All-Cause Mortality and Acute Myocardial Infarction Is Age-Dependent in Patients With Stable Angina Pectoris

Background: Red and processed meat intake have been associated with increased risk of morbidity and mortality, and a restricted intake is encouraged in patients with cardiovascular disease. However, evidence on the association between total meat intake and clinical outcomes in this patient group is lacking.Objectives: To investigate the association between total meat intake and risk of all-cause mortality, acute myocardial infarction, cancer, and gastrointestinal cancer in patients with stable angina pectoris. We also investigated whether age modified these associations.Materials and Methods: This prospective cohort study consisted of 1,929 patients (80% male, mean age 62 years) with stable angina pectoris from the Western Norway B-Vitamin Intervention Trial. Dietary assessment was performed by the administration of a semi-quantitative food frequency questionnaire. Cox proportional hazards models were used to investigate the association between a relative increase in total meat intake and the outcomes of interest.Results: The association per 50 g/1,000 kcal higher intake of total meat with morbidity and mortality were generally inconclusive but indicated an increased risk of acute myocardial infarction [HR: 1.26 (95% CI: 0.98, 1.61)] and gastrointestinal cancer [1.23 (0.70, 2.16)]. However, we observed a clear effect modification by age, where total meat intake was associated with an increased risk of mortality and acute myocardial infarction among younger individuals, but an attenuation, and even reversal of the risk association with increasing age.Conclusion: Our findings support the current dietary guidelines emphasizing a restricted meat intake in cardiovascular disease patients but highlights the need for further research on the association between meat intake and health outcomes in elderly populations. Future studies should investigate different types of meat separately in other CVD-cohorts, in different age-groups, as well as in the general population.

THE EFFECTS OF STOCKING DENSITY ON THE PERFORMANCE OF BROILER CHICKENS

THREE trials were conducted to determine the optimum stocking density for broiler chickens raised in a tropical environment In Trial 1, 100,67, 50,40, 34 and 29 birds were placed in duplicates in each pen with an area of 3.72 M2 to give stocking densities of 0.037, 0.056, 0.074, 0.093, 0.10 and 0 128 M2 per bird respectively. In Trial 2, stocking densities of 0.046, 0056, 0.064, 0.074, 0.083 and 0.093 M2 per bird were compared. Trial 3 involved studying the effects of providing equal feeder space (5cm/bird) or equal number of similar sized feeders (2 feeders per pen) when birds were stocked at floor spaces of 0.056, 0.064, 0.74, 0.083 and 0.093 sq meter per bird. Results showed that weight gain and feed consumption decreased, while total meat yield and net income per unit area increased, with increase in stocking rates. Feed efficiency, mortality and carcass dressing percentages were not significantly affected by the stocking rates. The effects of stocking densities on the performance of the birds were not altered by equalizing the feeder space per bird or by providing equal number of feeders per unit space. Management problems in terms of wetness of litter, feeding and watering were encountered with stocking densities of 0.037, 0.046 and 0.056 M2/ bird. Stocking rates of 0.083, 0.093, 0.10 and 0.128 M2 were uneconomic and did not produce superior performances to stocking densities of 0.064 or 0.074 M2/bird. On the basis of the results, floor spaces of 0.064 or 0.074 M2 per bird may be recommended as the optimum for broiler chickens raised in the tropics. The feeder space at these optimum stocking rates need not be more than 5cm per bird.