Modeling of Fatigue Wear of Viscoelastic Coatings

A new model for studying the kinetics of fatigue wear of a viscoelastic coating bonded to a rigid substrate is proposed. The fatigue mechanism is due to the cyclic interaction of the coating with a rough counterbody, which is modeled by a periodic system of smooth indenters. The study includes the solution of the problem of sliding contact of the indenter at a constant velocity along the viscoelastic coating, the calculation of stresses taking into account the mutual effect, and study of the process of damage accumulation in the material. The calculation of the damage function of the surface layer was carried out using the reduced stress criterion. Assuming the possibility of summation of accumulated damage, two processes were considered: delamination of surface layers of the coating and continuous fracture of the surface by the fatigue mechanism. The effect of the sliding velocity and viscoelastic properties of the material on the damage accumulation and the coating wear rate was analyzed. Two types of load, constant and stochastically varying, were used in modeling and analysis. It was found that the rate of fatigue wear of the coating increased and then became constant.

Damage Function of a Quasi-Brittle Material, Damage Rate, Acceleration and Jerk during Uniaxial Compression: Model and Application to Analysis of Trabecular Bone Tissue Destruction

A diversity of quasi-brittle materials can be observed in various engineering structures and natural objects (rocks, frozen soil, concrete, ceramics, bones, etc.). In order to predict the condition and safety of these objects, a large number of studies aimed at analyzing the strength of quasi-brittle materials has been conducted and presented in publications. However, at the modeling level, the problem of estimating the rate and acceleration of destruction of a quasi-brittle material under loading remains relevant. The purpose of the study was to substantiate the function of damage to a quasi-brittle material under uniaxial compression, determine the rate, acceleration and jerk of the damage process, and also to apply the results obtained to predicting the destruction of trabecular bone tissue. In accordance with the purpose of the study, the basic concepts of fracture mechanics and standard methods of mathematical modeling were used. The proposed model is based on the application of the previously obtained differentiable damage function without parameters. The results of the study are presented in the form of plots and analytical relations for computing the rate, acceleration and jerk of the damage process. Examples are given. The predicted peak of the combined effect of rate, acceleration and jerk of the damage process are found to be of practical interest as an additional criterion for destruction. The simulation results agree with the experimental data known from the available literature.

Economic damages due to extreme precipitation during tropical storms: evidence from Jamaica

This study investigates economic damage risk due to extreme rainfall during tropical storms in Jamaica. To this end, remote sensing precipitation data are linked to regional damage data for five storms. Extreme value modelling of precipitation is combined with an estimated damage function and satellite-derived nightlight intensity to estimate local risk in monetary terms. The results show that variation in maximum rainfall during a storm significantly contributes to parish level damages even after controlling for local wind speed. For instance, the damage risk for a 20 year rainfall event in Jamaica is estimated to be at least 238 million USD, i.e. about 1.5% of Jamaica’s yearly GDP.

Estimation of Nonlinear Static Damage Index for Seismic Assessment

The main objective of this study is, evaluation damage index of reinforced concrete moment resisting frames by” NONLINEAR STATIC PROCEDURE” nonlinear static analysis includes the capacity spectrum method (CSM) that uses the intersection of the capacity (pushover) curve and a reduced response spectrum to estimate maximum displacement in terms of damage of building. Nonlinear static procedure is simple and practical method for static damage index. For this purpose, first some functions are derived to estimate damage to the structure using pushover analysis and then designed procedure is proposed. In this study damage function is estimated by using correlation between park-ang damage index (NLDD) and nonlinear static damage index (NLSD) which is based on the pushover analysis. For this purpose dynamic and static damage damage analysis are performed on several concrete frames subjected to various earthquake acceleration records. So the detail explanation is found in this study.

The mortality cost of carbon

Many studies project that climate change can cause a significant number of excess deaths. Yet, in integrated assessment models (IAMs) that determine the social cost of carbon (SCC) and prescribe optimal climate policy, human mortality impacts are limited and not updated to the latest scientific understanding. This study extends the DICE-2016 IAM to explicitly include temperature-related mortality impacts by estimating a climate-mortality damage function. We introduce a metric, the mortality cost of carbon (MCC), that estimates the number of deaths caused by the emissions of one additional metric ton of CO2. In the baseline emissions scenario, the 2020 MCC is 2.26 × 10‒4 [low to high estimate −1.71× 10‒4 to 6.78 × 10‒4] excess deaths per metric ton of 2020 emissions. This implies that adding 4,434 metric tons of carbon dioxide in 2020—equivalent to the lifetime emissions of 3.5 average Americans—causes one excess death globally in expectation between 2020-2100. Incorporating mortality costs increases the 2020 SCC from $37 to $258 [−$69 to $545] per metric ton in the baseline emissions scenario. Optimal climate policy changes from gradual emissions reductions starting in 2050 to full decarbonization by 2050 when mortality is considered.

Expansion of CD10neg neutrophils and HLA-DRneg/low monocytes driving inflammatory responses after myocardial infarction

Background: Immature neutrophils and HLA-DRneg/low monocytes expand in cancer, autoimmune diseases and viral infections, but their appearance and immunoregulatory effects on T-cells after acute myocardial infarction (AMI) remain underexplored.Methods and Results: We found an expansion of circulating immature CD16+CD66b+CD10neg neutrophils and CD14+HLA-DRneg/low monocytes in AMI patients, correlating with cardiac damage, function and levels of immune-inflammation markers. Immature CD10neg neutrophils expressed high amounts of MMP-9 and S100A9, and displayed resistance to apoptosis. Moreover, we found that increased frequency of CD10neg neutrophils and elevated circulating IFN-γ levels were linked, mainly in patients with expanded CD4+CD28null T-cells. Notably, the expansion of circulating CD4+CD28null T-cells was associated with cytomegalovirus (CMV) seropositivity. Using bioinformatic tools we identified a tight relationship among the peripheral expansion of immature CD10neg neutrophils, CMV IgG titers, and circulating levels of IFN-γ and IL-12 in patients with AMI. At a mechanistic level, CD10neg neutrophils enhanced IFN-γ production by CD4+ T-cells through a contact-independent mechanism involving IL-12. In vitro experiments also highlighted that HLA-DRneg/low monocytes do not suppress T-cell proliferation but secrete high levels of pro-inflammatory cytokines after differentiation to macrophages and IFN-γ stimulation. Lastly, using a mouse model of AMI, we showed that immature neutrophils (CD11bposLy6GposCD101neg cells) are recruited to the injured myocardium and migrate to mediastinal lymph nodes shortly after reperfusion.Conclusions: Immunoregulatory functions of CD10neg neutrophils play a dynamic role in mechanisms linking myeloid cell compartment dysregulation, Th1-type immune responses and inflammation after AMI.