What informations should be extracted from the national programs for the prevention of congenital toxoplasmosis in Austria and in France?

2000 ◽  
pp. 299-303
Author(s):  
P. Ambroise-Thomas
Keyword(s):  
Congenital Toxoplasmosis ◽  
National Programs

EPIZOOTOLOGICAL FEATURES OF MODERN CATTLE LEUKEMIA

1970 ◽  
pp. 53-58
Author(s):  
V. V. Makarov ◽  
D. A. Lozovoy
Keyword(s):  
Dairy Cattle ◽  
Western Europe ◽  
Control Programs ◽  
Foreign Countries ◽  
Negative Order ◽  
Dairy Cattle Breeding ◽  
The Usa ◽  
Epizootic Process ◽  
National Programs

  Enzootic bovine leucosis (EBL) has been known for more than a century and a half. Its occurrence and registration may have historically been associated with intensive breeding of dairy cattle in Western Europe to increase target productivity. It is known that any limiting intervention in the nature of the animal organism is always accompanied by an uncontrolled and unpredictable change in the genotype of a wider range than the required, particularly negative order. In particular, a decrease in the resistance to macroorganisms and the possibility of the new diseases emergence, including infectious ones (for example, immunodeficiencies such as BLAD syndrome of black-motley cattle and stress syndrome in pigs, the occurrence of scrapie and other slow sheep infections). In the last two decades of the last century, in many disadvantaged countries, primarily Western European, national programs for the eradication of EBL have been developed and subsequently successfully implemented. First of all the motivation was the economy of dairy cattle breeding (mainly the extension of productive age, as well as the tightening of requirements in international trade in cattle and bull products, breeding, pricing, etc.). In an analytical article are reviewed the elements of epizootology of EBL in the foreign countries with special attention to the situation in the USA, scenarios of various control programs, and promising methods for assessing the role of infected animals in the epizootic process. A critical assessment of the problem of EBL in the Russian Federation is given, the reasons for the ineffectiveness of against leucosis measures are discussed.

Digital Transformation of Management, Economy, and Social Sphere: Reality and Prospects

2019 ◽  
pp. 26-31
Author(s):  
L. V. Achba ◽  
L. G. Vorona-Slivinskaya ◽  
E. V. Voskresenskaya
Keyword(s):  
Russian Federation ◽  
Institutional Environment ◽  
Digital Transformation ◽  
Social Sphere ◽  
Digital Reference ◽  
Stage Of Development ◽  
Current State ◽  
Information And Computer Technology ◽  
The Russian Federation ◽  
National Programs

The presented study examines the current state of the digital transformation of management, economy, and social sphere. The authors analyze the fundamental features of the digitalization of management, economy, and social sphere, namely: the mechanism of transformation of a considerable part of social and business interactions within the information and telecommunications space; development of remote forms of employment and transmission of information; active commercialization and use of digital currency and smart contracts; development of digital management.Aim. The study aims to substantiate the theoretical and methodological provisions on the current state of management, economy, and social sphere, and to develop practical recommendations on the improvement of the digital transformation of management, economy, and social sphere.Tasks. As part of the realization of the set aim, the authors solve the problems of examining the legal and regulatory framework of formation and development of the digital transformation of management, economy, and social sphere; analyzing the content of the digital transformation of management, economy, and social sphere in modern Russia; identifying the problems of the digital transformation of management, economy, and social sphere, and prospects for its development.Methods. The methodological basis of the study comprises the fundamental provisions of the modern economic theory, theories of public and municipal administration and those describing the functioning of the social sphere. The information basis of this study includes the laws and regulations of the Russian Federation, statistics of public institutions and science centers on the implementation of newinformation technologies, materials of national programs for the digitalization of the economy and social sphere.Results. The authors substantiate that at the current stage of development of management, economy, and social sphere, information and computer technology has a decisive impact on the technological and institutional environment within the society.Conclusions. Examination of indicators associated with the transformation of digital technology in management, economy, and social sphere makes it possible to conclude that the Russian Federation as a whole is making good progress in the digitalization of the examined sphere. However, by independently integrating into a digital reference system, Russia faces a key problem in the field of management. Digital technologies will not work without establishing relations between economic actors and their management in general. Without this synchronization, they cannot develop properly.

Integration of Ayurvedic Medicine in Public Health Delivery System at primary level for UHC - An Evidence Based Study.

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Rayeesa Zainab ◽  
Karthika P. ◽  
Irfanahemad A. S. ◽  
Gulappa M.D.
Keyword(s):  
Health Care ◽  
Economic Status ◽  
Ayurvedic Medicine ◽  
Evidence Based ◽  
Primary Level ◽  
Health Delivery ◽  
Ayurvedic Drugs ◽  
Choice Of Treatment ◽  
Health Delivery System ◽  
National Programs

Background: In developing country like India it is very difficult for people of low socio-economic status to get access to healthcare and in case they seek healthcare, cost of medicines becomes major reason for out of pocket expenditure, as all the medicines are not available in PHC. Objective: To collate Ayurvedic medicine with Allopathic medicine to provide choice of treatment to patient in view of UHC. Methods: A literature review on Ayurvedic drugs (single drug and formulations) was done after prioritizing the diseases for our study based on National programs and other frequently seen diseases in Primary healthcare (PHC). Evidence was collected in two ways, first by pure Ayurvedic evidence based on Samhitas and second was based on modern techniques and then tabulated. Results: Ayurvedic drug list for Primary Health Care was formulated based on available modern as well as Classical evidence and tabulated in the form of a table. Conclusion: Ayurvedic drugs can be integrated in PHC to provide universal health care at primary level.

Timing and type of prenatal treatment for congenital toxoplasmosis

2003 ◽  
Author(s):  
R Thiébaut ◽  
RE Gilbert ◽  
L Gras ◽  
G Chêne
Keyword(s):  
Congenital Toxoplasmosis ◽  
Prenatal Treatment

scholarly journals A Novel Calcium-Dependent Protein Kinase 1 Inhibitor Potently Prevents Toxoplasma gondii Transmission to Foetuses in Mouse

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4203
Author(s):  
Héloïse Débare ◽  
Nathalie Moiré ◽  
Firmin Baron ◽  
Louis Lantier ◽  
Bruno Héraut ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Toxoplasma Gondii ◽  
Intraperitoneal Administration ◽  
Congenital Toxoplasmosis ◽  
Parasite Burden ◽  
Oral Route ◽  
Dependent Protein Kinase ◽  
Calcium Dependent ◽  
Dependent Protein ◽  
Calcium Dependent Protein Kinase

Treatments currently used to prevent congenital toxoplasmosis are non-specific of Toxoplasma gondii and have grievous side effects. To develop a more specific and less toxic drug, we have designed SP230, an imidazo[1,2-b]pyridazine salt targeting the Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) and active against acute toxoplasmosis in mice. Efficiency of SP230 to inhibit foetal transmission of the parasite was evaluated in a mouse model of congenital toxoplasmosis. Swiss mice were infected at mid-pregnancy with tachyzoites or cysts of the ME49 strain of T. gondii by intraperitoneal and oral route, respectively, and treated with SP230 at 50 mg/kg for 5 days by the same routes. Parasite burden in organs of dams and in foetuses was measured by quantitative PCR. Intraperitoneal administration of SP230 drastically reduced the number of parasites (more than 97% of reduction) in the brain and lungs of dams, and led to a reduction of 66% of parasite burden in foetuses. Oral administration of SP230 was particularly efficient with 97% of reduction of parasite burdens in foetuses. SP230 did not impact number and weight of offspring in our conditions. This inhibitor of TgCDPK1 is a promising candidate for the development of alternative therapeutics to treat infected pregnant women.

scholarly journals Implementing Electromobility in Public Transport in Poland in 1990–2020. A Review of Experiences and Evaluation of the Current Development Directions

2021 ◽  
Vol 13 (7) ◽  
pp. 4009
Author(s):  
Marcin Połom ◽  
Paweł Wiśniewski
Keyword(s):  
Electric Vehicles ◽  
Public Transport ◽  
Online Survey ◽  
Small Towns ◽  
The European Union ◽  
Operational Capabilities ◽  
Electric Bus ◽  
Low Emission ◽  
National Programs ◽  
Regional Authorities

Public transport has undergone major changes in recent years. In particular, they relate to the issue of environmental impact. Due to the significant emission of pollutants from the economy, in particular from the transport segment, member states of the European Union have taken measures to limit its scope. Only low-emission and zero-emission vehicles are to be used in transport, and mainly those that are powered by electricity in public transport. The development of battery technologies has led to a revolution in the range and operational capabilities of electric buses in the last decade. They have become a seemingly easy alternative to traditional electric vehicles in public transport—trams and trolleybuses. This article presents the possibilities and limitations of the development of public transport in Poland based on electric buses. An attempt was made to review the literature and compare the possibility of the functioning of buses, trams and trolleybuses in the Polish socio-economic, environmental and technological conditions. The article was based on a literature query, an analysis of unpublished materials, and a qualitative analysis of national programs endorsing the idea of electromobility as well as an online survey on the perception of electric public transport. The main goal of the article was to identify and evaluate the possibilities of developing public transport in Poland with the use of electric buses. The main results of the work include the demonstration that the optics of the national and regional authorities in Poland are focused mainly on electric buses without a thorough analysis of the legitimacy of their operation, especially in small towns. The incentive in the form of subsidizing the purchase of an electric bus is sufficient for them, and the future effects of using electric buses are not investigated.

Congenital Toxoplasmosis: Missed Opportunities for Diagnosis and Prevention

2020 ◽  
Author(s):  
Raquel Aitken Soares Mueller ◽  
Ana Cristina Cisne Frota ◽  
Daniela Durão Menna Barreto ◽  
Daniela Pires Ferreira Vivacqua ◽  
Gabriela Bueno Loria ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Congenital Toxoplasmosis ◽  
First Trimester ◽  
University Hospital ◽  
Serological Testing ◽  
Missed Opportunities ◽  
Clinic Appointment ◽  
History Of ◽  
Acute Toxoplasmosis ◽  
Made In

Abstract Objectives Identify missed opportunities for the prevention and early diagnosis of congenital toxoplasmosis (CT) in infants followed up in a reference center for pediatric infectious diseases (PID) in Rio de Janeiro between January 2007 and December 2016. Methods Descriptive study including infants with CT, diagnosis established based on Brazil’s Ministry of Health’s criteria. All data regarding the infants and their mother’s prenatal care were collected from the medical records of the Instituto de Puericultura e Pediatria Martagão Gesteira (IPPMG)—a tertiary public pediatric university hospital. The study enrolled infants aged between 0 and 12 months followed up in the PID department of IPPMG and with confirmed infection by Toxoplasma gondii in the period between January 2007 and December 2016. All patients with diagnosis of CT registered in the PID database of the IPPMG and admitted in the above-mentioned period were included in the study. Patients whose records were not available, or who went to just one clinic appointment were excluded. Results The obstetric history of all 44 women, whose infants (45) were diagnosed with CT, was analyzed. Their median age was 22 years. None had undergone preconception serological testing for toxoplasmosis. Only 20 (45%) of them started antenatal care during the first trimester of gestation, a total of 24 (55%) had more than six antenatal care visits, and 16% of those did not undergo serological testing for toxoplasmosis. None were adequately informed of preventive measures. The diagnosis of acute toxoplasmosis was made in 50% of these pregnancies but 32% of the women were not treated. Only 10 children of these mothers were adequately screened and treated at birth. Conclusion Despite the existence of national recommendations, several opportunities were missed to prevent CT during the antenatal period and to diagnose and treat this condition in the neonatal period.

Sign in / Sign up

Export Citation Format

Share Document