Cellulose and Chitin Nanofibers: Potential Applications on Wound Healing

2021 ◽  
pp. 133-143
Author(s):  
Athira Johnson ◽  
M.S. Neelakandan ◽  
Jiya Jose ◽  
Sabu Thomas ◽  
Nandakumar Kalarikkal
Keyword(s):  
Wound Healing ◽  
Potential Applications ◽  
Chitin Nanofibers

scholarly journals Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Hamed Nosrati ◽  
Reza Aramideh Khouy ◽  
Ali Nosrati ◽  
Mohammad Khodaei ◽  
Mehdi Banitalebi-Dehkordi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Tissue Regeneration ◽  
Molecular Mechanisms ◽  
Healing Process ◽  
The Body ◽  
Key Factors ◽  
Potential Applications ◽  
Nanocomposite Scaffolds

AbstractSkin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life. Tissue engineering aims to improve the quality of damaged tissue regeneration. One of the most effective treatments for skin tissue regeneration is to improve angiogenesis during the healing period. Over the last decade, there has been an impressive growth of new potential applications for nanobiomaterials in tissue engineering. Various approaches have been developed to improve the rate and quality of the healing process using angiogenic nanomaterials. In this review, we focused on molecular mechanisms and key factors in angiogenesis, the role of nanobiomaterials in angiogenesis, and scaffold-based tissue engineering approaches for accelerated wound healing based on improved angiogenesis.

The veterinary nurse's role in the management of wound drains

2020 ◽  
Vol 11 (6) ◽  
pp. 264-269
Author(s):  
Evie Yon
Keyword(s):  
Wound Healing ◽  
Patient Outcomes ◽  
Wound Management ◽  
Surgical Reconstruction ◽  
Normal Process ◽  
Initial Management ◽  
Accurate Knowledge ◽  
Wound Breakdown ◽  
Potential Applications ◽  
The Ideal

Wound management is an exciting and well-researched area of veterinary medicine. It is a key area for veterinary nursing involvement from initial management to possible surgical reconstruction. An essential aspect of this is provision of the ideal wound environment to encourage normal and effective wound healing, and to reduce the incidence of wound breakdown and dehiscence. Throughout this clinical review, consideration will be given to the normal process of wound healing and how this can be assisted by drain placement. The types of drain used in practice, in addition to novel drainage techniques, will be considered throughout, as well as the veterinary nurse's role in their management. Comprehensive and accurate knowledge and understanding of different drain types, in addition to their potential applications, can help to ensure more informed veterinary nursing and, in turn, better wound healing and patient outcomes.

scholarly journals A New Generation of Electrospun Fibers Containing Bioactive Glass Particles for Wound Healing

Materials ◽  
2020 ◽  
Vol 13 (24) ◽  
pp. 5651
Author(s):  
Rachele Sergi ◽  
Valeria Cannillo ◽  
Aldo R. Boccaccini ◽  
Liliana Liverani
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Bioactive Glass ◽  
Flexible Structures ◽  
Biological Properties ◽  
Cellular Viability ◽  
Bioactive Glasses ◽  
Electrospinning Technique ◽  
Potential Applications ◽  
Biological Performance

Chitosan fibers blended with polyethylene oxide (CHIT_PEO) and crosslinked with genipin were fabricated by electrospinning technique. Subsequently, CHIT_PEO bioactive glass composite electrospun mats were fabricated with the aim to achieve flexible structures with adequate mechanical properties and improved biological performance respect to CHIT_PEO fibers, for potential applications in wound healing. Three different compositions of bioactive glasses (BG) were selected and investigated: 45S5 BG, a Sr and Mg containing bioactive glass (BGMS10) and a Zn-containing bioactive glass (BGMS_2Zn). Particulate BGs (particles size < 20 μm) were separately added to the starting CHIT_PEO solution before electrospinning. The two recently developed bioactive glasses (BGMS10 and BGMS_2Zn) showed very promising biological properties in terms of bioactivity and cellular viability; thus, such compositions were added for the first time to CHIT_PEO solution to fabricate composite electrospun mats. The incorporation of bioactive glass particles and their distribution into CHIT_PEO fibers were assessed by SEM and FTIR analyses. Furthermore, CHIT_PEO composite electrospun mats showed improved mechanical properties in terms of Young’s Modulus compared to neat CHIT_PEO fibers; on the contrary, the values of tensile strain at break (%) were comparable. Biological performance in terms of cellular viability was investigated by means of WST-8 assay and CHIT_PEO composite electrospun mats showed cytocompatibility and the desired cellular viability.

Bioactive glasses in wound healing: hope or hype?

2017 ◽  
Vol 5 (31) ◽  
pp. 6167-6174 ◽  
Author(s):  
Shiva Naseri ◽  
William C. Lepry ◽  
Showan N. Nazhat
Keyword(s):  
Wound Healing ◽  
Soft Tissue ◽  
Tissue Regeneration ◽  
Tissue Repair ◽  
Great Promise ◽  
Mineralized Tissue ◽  
Bioactive Glasses ◽  
Soft Tissue Repair ◽  
Potential Applications

Bioactive glasses have long been investigated in mineralized tissue regeneration, but recently their potential applications in soft tissue repair, and in particular wound healing, have demonstrated great promise.

scholarly journals Potential of Cyanobacteria in Wound Healing

2021 ◽  
Author(s):  
Laxmi Parwani ◽  
Mansi Shrivastava ◽  
Jaspreet Singh
Keyword(s):  
Wound Healing ◽  
Bioactive Compounds ◽  
Wound Care ◽  
Cost Effective ◽  
Wound Dressings ◽  
Potential Applications ◽  
Healing Agent ◽  
The Rich ◽  
Immense Potential ◽  
Insight Into

The wound care market is rapidly expanding due to the development of innumerable dressings that exhibit specific healing requirements for different wound types. The use of biomaterials as suitable wound dressing material is highly advantageous due to their biocompatibility, biodegradability, and non-toxicity. Cyanobacteria have been widely explored for their potential applications in wound healing, as they are the rich source of bioactive compounds with antibacterial, antitumor, antiviral, antioxidant, and antifungal activities. In recent years this group of organisms has been widely studied due to their immense potential in biomedical applications. Although their different bioactivities can support wound healing in different ways, very few forms have proven utility as a wound-healing agent. This chapter gives an insight into the potential of cyanobacteria in wound healing. Different bioactive compounds present in variable forms of cyanobacteria and their associated activities were reported to support tissue regeneration and wound healing acceleration. As the demand for cost-effective, bioactive wound care products is ever increasing, these organisms have immense potential to be utilized for the development of bioactive wound dressings. Hence, various bioactive compounds of cyanobacteria, their associated activities, and roles in wound healing have been briefly reviewed in this chapter.

scholarly journals A Review on Plant Cellulose Nanofibre-Based Aerogels for Biomedical Applications

Polymers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1759 ◽  
Author(s):  
H.P.S. Abdul Khalil ◽  
A.S. Adnan ◽  
Esam Bashir Yahya ◽  
N.G. Olaiya ◽  
Safrida Safrida ◽  
...  
Keyword(s):  
Wound Healing ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Functional Materials ◽  
Plant Fibre ◽  
Potential Applications ◽  
Antimicrobial Film ◽  
Cellulose Nanomaterials ◽  
Dressing Materials ◽  
Antibiotic Delivery

Cellulose nanomaterials from plant fibre provide various potential applications (i.e., biomedical, automotive, packaging, etc.). The biomedical application of nanocellulose isolated from plant fibre, which is a carbohydrate-based source, is very viable in the 21st century. The essential characteristics of plant fibre-based nanocellulose, which include its molecular, tensile and mechanical properties, as well as its biodegradability potential, have been widely explored for functional materials in the preparation of aerogel. Plant cellulose nano fibre (CNF)-based aerogels are novel functional materials that have attracted remarkable interest. In recent years, CNF aerogel has been extensively used in the biomedical field due to its biocompatibility, renewability and biodegradability. The effective surface area of CNFs influences broad applications in biological and medical studies such as sustainable antibiotic delivery for wound healing, the preparation of scaffolds for tissue cultures, the development of drug delivery systems, biosensing and an antimicrobial film for wound healing. Many researchers have a growing interest in using CNF-based aerogels in the mentioned applications. The application of cellulose-based materials is widely reported in the literature. However, only a few studies discuss the potential of cellulose nanofibre aerogel in detail. The potential applications of CNF aerogel include composites, organic–inorganic hybrids, gels, foams, aerogels/xerogels, coatings and nano-paper, bioactive and wound dressing materials and bioconversion. The potential applications of CNF have rarely been a subject of extensive review. Thus, extensive studies to develop materials with cheaper and better properties, high prospects and effectiveness for many applications are the focus of the present work. The present review focuses on the evolution of aerogels via characterisation studies on the isolation of CNF-based aerogels. The study concludes with a description of the potential and challenges of developing sustainable materials for biomedical applications.

scholarly journals Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing

2020 ◽  
Vol Volume 15 ◽  
pp. 9717-9743
Author(s):  
Que Bai ◽  
Kai Han ◽  
Kai Dong ◽  
Caiyun Zheng ◽  
Yanni Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Wound ◽  
Potential Applications ◽  
Diabetic Wound Healing

scholarly journals Biosynthesis of Silver Nanoparticles and Its Applications

2015 ◽  
Vol 2015 ◽  
pp. 1-18 ◽  
Author(s):  
M. Jannathul Firdhouse ◽  
P. Lalitha
Keyword(s):  
Wound Healing ◽  
Silver Nanoparticles ◽  
Critical Review ◽  
Characterization Techniques ◽  
Potential Applications ◽  
Insight Into

Silver nanoparticles possess unique properties which find myriad applications such as antimicrobial, anticancer, larvicidal, catalytic, and wound healing activities. Biogenic syntheses of silver nanoparticles using plants and their pharmacological and other potential applications are gaining momentum owing to its assured rewards. This critical review is aimed at providing an insight into the phytomediated synthesis of silver nanoparticles, its significant applications in various fields, and characterization techniques involved.

scholarly journals Collagen/Chitosan Gels Cross-Linked with Genipin for Wound Healing in Mice with Induced Diabetes

Materials ◽  
2021 ◽  
Vol 15 (1) ◽  
pp. 15
Author(s):  
Balzhima Shagdarova ◽  
Mariya Konovalova ◽  
Yuliya Zhuikova ◽  
Alexey Lunkov ◽  
Vsevolod Zhuikov ◽  
...  
Keyword(s):  
Wound Healing ◽  
Wound Closure ◽  
Collagen Deposition ◽  
Sebaceous Glands ◽  
Hemostatic Effect ◽  
Potential Applications ◽  
Low Toxicity ◽  
Cd1 Mice ◽  
Diabetic Wounds ◽  
Timp1 Gene

Diabetes mellitus continues to be one of the most common diseases often associated with diabetic ulcers. Chitosan is an attractive biopolymer for wound healing due to its biodegradability, biocompatibility, mucoadhesiveness, low toxicity, and hemostatic effect. A panel of hydrogels based on chitosan, collagen, and silver nanoparticels were produced to treat diabetic wounds. The antibacterial activity, cytotoxicity, swelling, rheological properties, and longitudinal sections of hydrogels were studied. The ability of the gels for wound healing was studied in CD1 mice with alloxan-induced diabetes. Application of the gels resulted in an increase in VEGF, TGF-b1, IL-1b, and TIMP1 gene expression and earlier wound closure in a comparison with control untreated wounds. All gels increased collagen deposition, hair follicle repair, and sebaceous glands formation. The results of these tests show that the obtained hydrogels have good mechanical properties and biological activity and have potential applications in the field of wound healing. However, clinical studies are required to compare the efficacy of the gels as animal models do not reproduce full diabetes pathology.

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