Cost-effective biogenic-production of inorganic nanoparticles, characterizations, and their antimicrobial properties

2022 ◽  
pp. 265-290
Author(s):  
Kishore Kumar Kadimpati ◽  
Narasimha Golla
Author(s):  
Nilushi Indika Bamunu Arachchige ◽  
Fazlurrahman Khan ◽  
Young-Mog Kim

Background: The treatment of infection caused by pathogenic bacteria becomes one of the serious concerns globally. The failure in the treatment was found due to the exhibition of multiple resistance mechanisms against the antimicrobial agents. Emergence of resistant bacterial species has also been observed due to prolong treatment using conventional antibiotics. To combat these problems, several alternative strategies have been employed using biological and chemically synthesized compounds as antibacterial agents. Marine organisms considered as one of the potential sources for the isolation of bioactive compounds due to the easily available, cost-effective, and eco-friendly. Methods: The online search methodology was adapted for the collection of information related to the antimicrobial properties of marine-derived compounds. These compound has been isolated and purified by different purification techniques, and their structure also characterized. Furthermore, the antibacterial activities have been reported by using broth microdilution as well as disc diffusion assays. Results: The present review paper describes the antimicrobial effect of diverse secondary metabolites which are isolated and purified from the different marine organisms. The structural elucidation of each secondary metabolite has also been done in the present paper, which will help for the in silico designing of the novel and potent antimicrobial compounds. Conclusion: A thorough literature search has been made and summarizes the list of antimicrobial compounds that are isolated from both prokaryotic and eukaryotic marine organisms. The information obtained from the present paper will be helpful for the application of marine compounds as antimicrobial agents against different antibiotic-resistant human pathogenic bacteria.


Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 380 ◽  
Author(s):  
Diana Rafael ◽  
Fernanda Andrade ◽  
Francesc Martinez-Trucharte ◽  
Jana Basas ◽  
Joaquín Seras-Franzoso ◽  
...  

Hydrogels (HG) have recognized benefits as drug delivery platforms for biomedical applications. Their high sensitivity to sterilization processes is however one of the greatest challenges regarding their clinical translation. Concerning infection diseases, prevention of post-operatory related infections is crucial to ensure appropriate patient recovery and good clinical outcomes. Silver nanoparticles (AgNPs) have shown good antimicrobial properties but sustained release at the right place is required. Thus, we produced and characterized thermo-sensitive HG based on Pluronic® F127 loaded with AgNPs (HG-AgNPs) and their integrity and functionality after sterilization by dry-heat and autoclave methods were carefully assessed. The quality attributes of HG-AgNPs were seriously affected by dry-heat methods but not by autoclaving methods, which allowed to ensure the required sterility. Also, direct sterilization of the final HG-AgNPs product proved more effective than of the raw material, allowing simpler production procedures in non-sterile conditions. The mechanical properties were assessed in post mortem rat models and the HG-AgNPs were tested for its antimicrobial properties in vitro using extremely drug-resistant (XDR) clinical strains. The produced HG-AgNPs prove to be versatile, easy produced and cost-effective products, with activity against XDR strains and an adequate gelation time and spreadability features and optimal for in situ biomedical applications.


2012 ◽  
Vol 4 (4) ◽  
pp. 279-287 ◽  
Author(s):  
R. G. S. V. Prasad ◽  
J. L. Endrino ◽  
Nishanth Kumar Jain ◽  
Goutham Reddy ◽  
D. Basavaraju ◽  
...  

2020 ◽  
Vol 13 (3) ◽  
pp. 203-209
Author(s):  
Sumathi . P

This study was involved to synthesize and investigate the antimicrobial properties of highly pure nanocrystalline SnO2 by simple chemical method. In the nanorods, SnO2 nanoparticles, with a size of about 74 nm, the SnO2 nanoparticles were maximum antibacterial activity against both bacterial and fungal with the zone of inhibition for Klebsiella pneumoniae, Staphylococcus aures, Salmonella typhi and Ascerpergillus Flavus, Ascerpergillus Niger from 25μg/ml and 100 μg/ml respectively. SnO2 nanoparticles showed good activity against both Gram-negative and Gram-positive bacteria confirming these as future broad spectrum antibacterial a cost effective way and to study its antimicrobial properties. We observed an effective antibacterial and antifungal activity of the SnO2 nanoparticle against bacteria and fungi. The results showed that SnO2 nanoparticles enhanced the good antibacterial activity.


Plants ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 357 ◽  
Author(s):  
Himashree Bora ◽  
Madhu Kamle ◽  
Dipendra Kumar Mahato ◽  
Pragya Tiwari ◽  
Pradeep Kumar

Citrus is a genus belonging to the Rutaceae family and includes important crops like orange, lemons, pummelos, grapefruits, limes, etc. Citrus essential oils (CEOs) consist of some major biologically active compounds like α-/β-pinene, sabinene, β-myrcene, d-limonene, linalool, α-humulene, and α-terpineol belonging to the monoterpenes, monoterpene aldehyde/alcohol, and sesquiterpenes group, respectively. These compounds possess several health beneficial properties like antioxidant, anti-inflammatory, anticancer, etc., in addition to antimicrobial properties, which have immense potential for food applications. Therefore, this review focused on the extraction, purification, and detection methods of CEOs along with their applications for food safety, packaging, and preservation. Further, the concerns of optimum dose and safe limits, their interaction effects with various food matrices and packaging materials, and possible allergic reactions associated with the use of CEOs in food applications were briefly discussed, which needs to be addressed in future research along with efficient, affordable, and “green” extraction methods to ensure CEOs as an ecofriendly, cost-effective, and natural alternative to synthetic chemical preservatives.


2021 ◽  
Vol 7 (2) ◽  
pp. 79-85
Author(s):  
Adriana Yazik ◽  
Nur Azira Tukiran

Packaging is a critical process in the food industry because it is used to prevent spoilage, extend shelf-life, and provide an attractive presentation of the food product. Plastic packaging is used all over the world, and its production is increasing year after year. It comes in a variety of colours and designs. However, it has caused serious environmental problems, particularly to the ocean that has become a place for discarded plastic packaging. To address this issue, biodegradable packaging was developed to replace the use of plastic packaging because it helps to reduce environmental impact and waste management costs. Biodegradable packaging is also known as environmentally friendly packaging because it can be degraded into carbon dioxide, water, inorganic compounds, and biomass by microorganisms, algae, fungi, as well as enzyme catalysts. Biodegradable biocomposite film such as starch, cellulose, chitosan, and polyvinyl alcohol (PVA) is required to produce biodegradable packaging. Therefore, this paper aims to characterize PVA as a biocomposite film in biodegradable packaging. PVA has excellent properties to form films, as well as biodegradable, abundant in the environment, and cost-effective. However, it has some limitations in terms of thickness and mechanical properties; thus, the incorporation of PVA with essential oils and fiber is required to improve its mechanical properties, thickness, and provide antimicrobial properties to the packaging. 


Cavitation ◽  
2014 ◽  
pp. 263-300
Author(s):  
Aharon Gedanken ◽  
Nina Perkas ◽  
Ilana Perelshtein ◽  
Guy Applerot ◽  
Anat Lipovsky ◽  
...  

2014 ◽  
Vol 2 (21) ◽  
pp. 3221-3231 ◽  
Author(s):  
Marcela Elisabeta Barbinta-Patrascu ◽  
Camelia Ungureanu ◽  
Stefan Marian Iordache ◽  
Ioana Raluca Bunghez ◽  
Nicoleta Badea ◽  
...  

A novel, simple and cost-effective bottom-up approach was developed to achieve antioxidant and antimicrobial biohybrids based on biomimetic membranes, phyto-nanosilver and single-walled carbon nanotubes.


2021 ◽  
Vol 22 (7) ◽  
pp. 3316
Author(s):  
Carlos Sainz-Urruela ◽  
Soledad Vera-López ◽  
María Paz San San Andrés ◽  
Ana M. Díez-Pascual

Over the last years, different nanomaterials have been investigated to design highly selective and sensitive sensors, reaching nano/picomolar concentrations of biomolecules, which is crucial for medical sciences and the healthcare industry in order to assess physiological and metabolic parameters. The discovery of graphene (G) has unexpectedly impulsed research on developing cost-effective electrode materials owed to its unique physical and chemical properties, including high specific surface area, elevated carrier mobility, exceptional electrical and thermal conductivity, strong stiffness and strength combined with flexibility and optical transparency. G and its derivatives, including graphene oxide (GO) and reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the area of optical and electrochemical sensors. The presence of oxygenated functional groups makes GO nanosheets amphiphilic, facilitating chemical functionalization. G-based nanomaterials can be easily combined with different types of inorganic nanoparticles, including metals and metal oxides, quantum dots, organic polymers, and biomolecules, to yield a wide range of nanocomposites with enhanced sensitivity for sensor applications. This review provides an overview of recent research on G-based nanocomposites for the detection of bioactive compounds, providing insights on the unique advantages offered by G and its derivatives. Their synthesis process, functionalization routes, and main properties are summarized, and the main challenges are also discussed. The antioxidants selected for this review are melatonin, gallic acid, tannic acid, resveratrol, oleuropein, hydroxytyrosol, tocopherol, ascorbic acid, and curcumin. They were chosen owed to their beneficial properties for human health, including antibiotic, antiviral, cardiovascular protector, anticancer, anti-inflammatory, cytoprotective, neuroprotective, antiageing, antidegenerative, and antiallergic capacity. The sensitivity and selectivity of G-based electrochemical and fluorescent sensors are also examined. Finally, the future outlook for the development of G-based sensors for this type of biocompounds is outlined.


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