Fish consumption and the incidence of cerebrovascular disease

Studies of the beneficial role of fish consumption in the prevention of CVD are not consistent in their findings, particularly those studies that focus on the risk of stroke. The aim of the present study is to investigate the relationship between the consumption of different types of fish and the subsequent incidence of cerebrovascular disease (CVA). We prospectively evaluated the association between consumption of different types of fish and CVA in 3958 men and women aged 40–79 years who were free of heart disease and had participated in a health examination survey from 1967 to 1972. A total of 659 incident cases of CVA occurred during a follow-up until the end of 1994. A dietary history interview method provided data on habitual consumption of fish and other foods over the preceding year at baseline. Total fish intake did not predict CVA, but consumption of salted fish suggested an increased risk of intracerebral haemorrhage. The relative risk of intracerebral haemorrhage between the highest tertile of salted fish consumption and non-consumers was 1·98 (95 % CI 1·02, 3·84; P for trend = 0·06) after adjustment for age, sex, energy intake, smoking, BMI, physical activity, geographic area, occupation, diabetes, use of post-menopausal hormones, serum cholesterol, hypertension, and consumptions of butter, vegetables, fruits and berries. The relationship between fish consumption and stroke risk is not straightforward. How the fish is prepared for consumption may play an important role, affecting the association.

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Intake of fish and long-chain n−3 fatty acids and the risk of coronary heart mortality in men and women

British Journal Of Nutrition ◽

10.1079/bjn20051687 ◽

2006 ◽

Vol 95 (4) ◽

pp. 824-829 ◽

Cited By ~ 49

Author(s):

Ritva Järvinen ◽

Paul Knekt ◽

Harri Rissanen ◽

Antti Reunanen

Keyword(s):

Fatty Acids ◽

Fish Consumption ◽

Geographical Area ◽

Food Composition ◽

Health Examination ◽

Dietary History ◽

Interview Method ◽

The Relationship ◽

Long Chain

This prospective study investigated the relationship between the consumption of fish and intake of long-chain n−3 fatty acids and the risk of coronary heart mortality in 2775 men and 2445 women aged from 30 to 79 years who were free of CHD and had participated in a health examination survey from 1967 to 1972. In total, 335 men and 163 women died of CHD during a follow-up until the end of 1992. A dietary history interview method provided data on habitual consumption of fish and other foods over the preceding year at baseline. The intakes of long-chain n−3 fatty acids were calculated on the basis of food composition values of Finnish foods. Higher consumption of fish was associated with a decreased risk of CHD among women, whereas no significant association was seen among men. The relative risk between the highest and the lowest quintile for fish consumption was 1·00 (95% CI 0·70, 1·43; p for trend 0·83) for men and 0·59 (95% CI 0·36, 0·99; p for trend 0·02) for women in analysis adjusting for age, energy intake, geographical area, BMI, serum cholesterol, blood pressure, smoking, occupation and diabetes; however, after adjustment for dietary confounders this association was no longer significant. The intake of n−3 fatty acids was not significantly associated with the risk of CHD in either men or women. In conclusion, our results for women are in line with the suggested protective effect of fish consumption against CHD but a similar association was not, however, found in men.

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Association of Urinary and Plasma Levels of Trimethylamine N-Oxide (TMAO) with Foods

Nutrients ◽

10.3390/nu13051426 ◽

2021 ◽

Vol 13 (5) ◽

pp. 1426

Author(s):

Mauro Lombardo ◽

Giovanni Aulisa ◽

Daniele Marcon ◽

Gianluca Rizzo ◽

Maria Grazia Tarsisano ◽

...

Keyword(s):

Gut Microbiota ◽

Fish Consumption ◽

Plasma Levels ◽

Cooking Methods ◽

Saltwater Fish ◽

Increased Risk ◽

Mediator Role ◽

Fish And Shellfish ◽

The Relationship

Introduction: Trimethylamine N-oxide (TMAO) may play a key mediator role in the relationship between the diet, gut microbiota and cardiovascular diseases, particularly in people with kidney failure. The aim of this review is to evaluate which foods have a greater influence on blood or urinary trimethylamine N-oxide (TMAO) levels. Methods: 391 language articles were screened, and 27 were analysed and summarized for this review, using the keywords “TMAO” AND “egg” OR “meat” OR “fish” OR “dairy” OR “vegetables” OR “fruit” OR “food” in December 2020. Results: A strong correlation between TMAO and fish consumption, mainly saltwater fish and shellfish, but not freshwater fish, has been demonstrated. Associations of the consumption of eggs, dairy and meat with TMAO are less clear and may depend on other factors such as microbiota or cooking methods. Plant-based foods do not seem to influence TMAO but have been less investigated. Discussion: Consumption of saltwater fish, dark meat fish and shellfish seems to be associated with an increase in urine or plasma TMAO values. Further studies are needed to understand the relationship between increased risk of cardiovascular disease and plasma levels of TMAO due to fish consumption. Interventions coupled with long-term dietary patterns targeting the gut microbiota seem promising.

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Hubungan Gaya Hidup Dengan Kejadian Hipertensi Pada Pasien Rawat Jalan di Puskesmas Pagesangan Periode Juli 2019

Lumbung Farmasi: Jurnal Ilmu Kefarmasian ◽

10.31764/lf.v1i1.1635 ◽

2020 ◽

Vol 1 (1) ◽

pp. 34

Author(s):

Nur Furqani ◽

Cyntiya Rahmawati ◽

Melianti Melianti

Keyword(s):

Health Center ◽

Significant Relationship ◽

Fish Consumption ◽

Healthy Lifestyle ◽

Case Control ◽

Alcoholic Beverages ◽

Chi Square ◽

Salted Fish ◽

Chi Square Test ◽

The Relationship

ABSTRAKHipertensi merupakan tekanan darah tinggi yang bersifat abnormal dengan angka sistolik dan diastolik menunjukan angka lebih tinggi dari 140/90mmHg Hubungan gaya hidup dengan kejadian hipertensi sangat mempengaruhi beberapa kondisi psikis maupun seseorang. Gaya hidup yang sehat menggambarkan pola perilaku sehari-hari yang mengarah pada upaya memelihara kondisi fisik, dan mental sosial berada dalam keadaan positf. Gaya hidup sehat yang meliputi kebiasaan tidur, makan, pengendalian berat badan, tidak merokok, minum-minuman beralkohol, berolahraga secara teratur dan mengendalikan stres, untuk mendapatkan kesehatan yang baik yaitu dengan merubah gaya hidup dalam menjaga kesehatan. Penelitian ini bertujuan untuk mengetahui hubungangaya hidup dengan kejadian hipertensi pada pasien rawat jalan di Puskesmas Pagesangan periode juli 2019. Penelitian ini menggunakan metode observasi analitik dengan desain penelitian case control dan dianalisi mengunakan uji Chi square Pengambilan data yang dilakukan yaitu dengan cara wawancara langsung dengan menggunakan kuesioner yang diberikan pada responden yang akan diteliti dengan jumlah sampel sebanyak 80 responden diambil berdasarkan kurun waktu penelitian . gaya hidup dengan kejadian hipertensi yang diteliti pada penelitian ini adalah olahraga, merokok, konsumsi ikan asin, konsumsi bayam, konsumsi gorengan, dan konsumsi pisang. Kemudian dianalis dengan menggunakan spss uji chi square. Hasil penelitian penelitian Hubungan Gaya Hidup Dengan Kejadian Hipertensi Pasien Rawat Jalan Di Puskesmas Pagesangan Periode Juli 2019 menunjukan adanya hubungan yang signifikan pada gaya hidup yaitu olahraga p= 0,00, merokok p=0,00, konsumsi bayamp=0,00, konsumsi gorengan p=0,001, konsumsi pisang p=0,001, sedangkan yang menunjukan tidak adanya hubungan yang signifikan adalah gaya hidup konsumsi ikan asin p= 0,263. Kata kunci : Hipertensi; Gaya Hidup; Puskesmas Pagesangan. ABSTRACTHypertension is an abnormally high blood pressure with systolic and diastolic numbers higher than 140 / 90mmHg lifestyle relationship with the incidence of hypertension greatly affects several psychological conditions and a person. A healthy lifestyle describes daily behavioral patterns that lead to efforts to maintain physical condition, and social mentality is in a positive state. A healthy lifestyle that includes sleeping, eating, weight control, not smoking, drinking alcoholic beverages, exercising regularly and controlling stress, to get good health by changing lifestyle in maintaining health. This study aims to determine the relationship of lifestyle with the incidence of hypertension in outpatients in the Pagesangan Health Center in July 2019. This study uses analytical observation methods with a case control research design and analyzed using the Chi square test. Data collection was carried out by means of direct interviews using questionnaire given to respondents to be studied with a total sample of 80 respondents taken based on the period of research. lifestyle with the incidence ofhypertension studied in this study are exercise, smoking, consumption of salted fish, consumption of spinach, consumption of fried foods, and consumption of bananas. Then analyzed using the chi square test spss. The results of the study of the Relationship between Lifestyle and Outpatient Hypertension in the Pagesangan Health Center in the period of July 2019 showed a significant relationship to lifestyle, namely exercise p = 0.00, smoking p = 0.00, spinach consumption p = 0.00, consumption fried food p = 0,001, consumption of banana p = 0,001, while the one that shows no significant relationship is the lifestyle of salted fish consumption p = 0,263. Keywords : Hypertension; Lifestyle; community health center of Pagesangan.

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Abstract P104: Dietary Polychlorinated biphenyls and Long-chain Omega-3 Fish fatty acids Exposures and Risk of Heart Failure

Circulation ◽

10.1161/circ.137.suppl_1.p104 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Maria Kippler ◽

Carolina Donat Vargas ◽

Marika Berglund ◽

Anders Glynn ◽

Alicja Wolk ◽

...

Keyword(s):

Risk Factors ◽

Heart Failure ◽

Fatty Acids ◽

Polychlorinated Biphenyls ◽

Fish Consumption ◽

Omega 3 ◽

Increased Risk ◽

Incident Cases ◽

Long Chain ◽

Pcb Exposure

The potential beneficial effects of fish consumption on heart failure (HF) may be modified by major food contaminants in fish. Polychlorinated biphenyls (PCBs) in particular, have been associated with well-established risk factors of HF such as coronary heart disease, hypertension, and diabetes. Likewise, experimental and cross-sectional studies in humans suggest that PCB exposure may be involved in the development of HF. We aimed to assess the association of both dietary PCB and long-chain omega-3 fish fatty acids exposures with risk of HF in two large population-based prospective cohorts. We used the Swedish Mammography Cohort and the Cohort of Swedish Men, comprising 32,867 women and 36,545 men, free of cancer, heart failure, myocardial infarction and diabetes at baseline in 1997. A questionnaire on diet (96-food items) and lifestyle factors was completed at baseline. We calculated validated estimates of dietary PCB exposure and intake of long-chain omega-3 fish fatty acids [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)]. First incident cases of HF were ascertained through computerized linkage to the National Patient Register and the Cause of Death Register, defined as hospitalizations for (listed as the primary diagnosis) or death from HF. We use multivariable-adjusted Cox regression to estimate hazard ratio (HR) and its 95% confidence interval (CI), by quintiles of dietary PCB and EPA/DHA and controlling for known HF risk factors. During an average of 12 years of follow-up, 1,263 and 1,606 first incident cases of HF were ascertained in women and men, respectively. In multivariable-adjusted models, we observed no association between dietary PCB exposure or EPA/DHA intake and risk of HF. However, after additional mutual adjustments for PCBs and EPA/DHA, HRs for dietary PCB exposure were 1.60 (95% CI, 1.08-2.38) among women and 1.40 (95% CI, 0.97-2.02) among men, comparing extreme quintiles. The corresponding HRs for EPA/DHA intake were 0.62 (95% CI, 0.42-0.92) and 0.79 (95% CI, 0.55-1.13), respectively. Dietary exposure to PCBs was associated with an increased risk of HF in women, while EPA/DHA intake was associated with a lower risk of HF. Results for men was less evident but showed a similar trend. The results provide important information regarding the risk-benefit analysis of fish consumption, especially in cardiovascular disease prevention.

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Late-Onset Epilepsy and Occult Cerebrovascular Disease

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/jcbfm.2014.25 ◽

2014 ◽

Vol 34 (4) ◽

pp. 564-570 ◽

Cited By ~ 25

Author(s):

Lorna M Gibson ◽

Martha F Hanby ◽

Sarah M Al-Bachari ◽

Laura M Parkes ◽

Stuart M Allan ◽

...

Keyword(s):

Cerebrovascular Disease ◽

Late Onset ◽

Cerebral Metabolism ◽

Neurovascular Unit ◽

Barrier Dysfunction ◽

Increased Risk ◽

Antiepileptic Drug Treatment ◽

History Of ◽

Ischemic Attack ◽

The Relationship

The interface between cerebrovascular disease (CVD) and epilepsy is complex and multifaceted. Late-onset epilepsy (LOE) is increasingly common and is often attributed to CVD, and is indeed associated with an increased risk of stroke. This relationship is easily recognizable where there is a history of stroke, particularly involving the cerebral cortex. However, the relationship with otherwise occult, subcortical CVD is currently less well established yet causality is often invoked. In this review, we consider the diagnosis of LOE in clinical practice—including its behaviour as a potential mimic of acute ischemic stroke and transient ischemic attack; evidence for an association between occult CVD and LOE; and potential mechanisms of epileptogenesis in occult CVD, including potential interrelationships between disordered cerebral metabolism and perfusion, disrupted neurovascular unit integrity, blood–brain barrier dysfunction, and inflammation. We also discuss recently recognized issues concerning antiepileptic drug treatment and vascular risk and consider a variety of less common CVD entities associated with seizures.

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Age, Sickness, and Longevity in the Late Nineteenth and the Early Twentieth Centuries

Social Science History ◽

10.1017/s0145553200013596 ◽

2006 ◽

Vol 30 (4) ◽

pp. 571-600

Author(s):

Martin Gorsky ◽

Bernard Harris ◽

Andrew Hinde

Keyword(s):

Old Age ◽

Early Adulthood ◽

Older Men ◽

Risk Of Death ◽

Increased Risk ◽

Different Types ◽

Younger Men ◽

Late Nineteenth ◽

The Relationship ◽

Sick Pay

We examine the relationship between age, sickness, and longevity among men who were members of the Hampshire Friendly Society (HFS) in southern England during the late nineteenth and the early twentieth centuries. The HFS insured its members against sickness, death, and old age, keeping detailed records of the claims for sick pay submitted by its members from 1868 onward. From 1892 onward these records included information about the cause of the sickness for which compensation was paid. We can therefore use this information to construct individual “sickness biographies” for men who joined the society during this period. This article uses these sickness histories to address two questions. The first concerns the relationship between the age of the society’s members and the nature of the claims they submitted. We find that both the incidence and the duration of periods of sickness increased with age. Older men experienced longer periods of sickness both because they experienced different types of sickness and because it took them longer to recover from the same illnesses as those suffered by younger men. The second question is whether sickness in early adulthood was associated with increased mortality. We find that repeated bouts of sickness, as revealed by the number of claims made for sick pay, at ages under 50 years were associated with an increased risk of death at ages over 50 years.

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Plant foods and the risk of cerebrovascular diseases: a potential protection of fruit consumption

British Journal Of Nutrition ◽

10.1017/s0007114509359097 ◽

2009 ◽

Vol 102 (7) ◽

pp. 1075-1083 ◽

Cited By ~ 66

Author(s):

Anna Mizrahi ◽

Paul Knekt ◽

Jukka Montonen ◽

Maarit A. Laaksonen ◽

Markku Heliövaara ◽

...

Keyword(s):

Cerebrovascular Disease ◽

Ischaemic Stroke ◽

Intracerebral Haemorrhage ◽

Disease Incidence ◽

Cerebrovascular Diseases ◽

Cruciferous Vegetables ◽

Health Examination ◽

Inverse Association ◽

Fruit Consumption ◽

Plant Foods

Studies on the association between plant foods and cerebrovascular diseases have given contradictory results suggesting the existence of some effect-modifying factors. The present study determines whether the consumption of plant foods (i.e. fruits and berries, vegetables, and cereals) predicts a decreased cerebrovascular disease incidence in a population with low fruit and vegetable and high wholegrain intake. This cohort study on 3932 men and women was based on data from the Finnish Mobile Clinic Health Examination Survey, conducted in 1968–72. The participants were 40–74 years of age and free of cardiovascular diseases at baseline. Data on the plant food consumption were derived from a 1-year dietary history interview. During a 24-year follow-up 625 cases of cerebrovascular diseases occurred, leading to either hospitalisation or death. An inverse association was found between fruit consumption and the incidence of cerebrovascular diseases, ischaemic stroke and intracerebral haemorrhage. The adjusted relative risks (RR) between the highest and lowest quartiles of intake of any cerebrovascular disease, ischaemic stroke and intracerebral haemorrhage were 0·75 (95 % CI 0·59, 0·94), 0·73 (95 % CI 0·54, 1·00) and 0·47 (95 % CI 0·24, 0·92), respectively. These associations were primarily due to the consumption of citrus fruits and occurred only in men. Total consumption of vegetables or cereals was not associated with the cerebrovascular disease incidence. The consumption of cruciferous vegetables, however, predicted a reduced risk of cerebrovascular diseases (RR 0·79; 95 % CI 0·63, 0·99), ischaemic stroke (RR 0·67; 95 % CI 0·49, 0·92) and intracerebral haemorrhage (RR 0·49; 95 % CI 0·25, 0·98). In conclusion, the consumption of fruits, especially citrus, and cruciferous vegetables may protect against cerebrovascular diseases.

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Fast-food and commercial baked goods consumption and the risk of depression

Public Health Nutrition ◽

10.1017/s1368980011001856 ◽

2011 ◽

Vol 15 (3) ◽

pp. 424-432 ◽

Cited By ~ 124

Author(s):

Almudena Sánchez-Villegas ◽

Estefania Toledo ◽

Jokin de Irala ◽

Miguel Ruiz-Canela ◽

Jorge Pla-Vidal ◽

...

Keyword(s):

Fast Food ◽

Cox Regression ◽

Antidepressant Medication ◽

Baked Goods ◽

Depression Risk ◽

Increased Risk ◽

Incident Cases ◽

The Relationship

AbstractObjectiveWhereas the relationship between some components of diet, such as n-3 fatty acids and B-vitamins, and depression risk has been extensively studied, the role of fast-food or processed pastries consumption has received little attention.DesignConsumption of fast food (hamburgers, sausages, pizza) and processed pastries (muffins, doughnuts, croissants) was assessed at baseline through a validated semi-quantitative FFQ. Participants were classified as incident cases of depression if they reported a physician diagnosis of depression or the use of antidepressant medication in at least one of the follow-up questionnaires. Cox regression models were fit to assess the relationship between consumption of fast food and commercial baked goods and the incidence of depression.SettingThe SUN (Seguimiento Universidad de Navarra – University of Navarra Follow-up) Project, Spain.SubjectsParticipants (n 8964) from a Spanish cohort.ResultsAfter a median follow-up of 6·2 years, 493 cases of depression were reported. A higher risk of depression was associated with consumption of fast food (fifth (Q5) v. first quintile (Q1): hazard ratio (HR) = 1·36; 95 % CI 1·02, 1·81; P trend = 0·003). The results did not change after adjustment for the consumption of other food items. No linear relationship was found between the consumption of commercial baked goods and depression. Participants belonging to consumption quintiles Q2–Q5 showed an increased risk of depression compared with those belonging to the lowest level of consumption (Q1; HR = 1·38; 95 % CI 1·06, 1·80).ConclusionsFast-food and commercial baked goods consumption may have a detrimental effect on depression risk.

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The relationship between handedness and risk of multiple sclerosis

Multiple Sclerosis Journal ◽

10.1177/1352458509102622 ◽

2009 ◽

Vol 15 (5) ◽

pp. 587-592 ◽

Cited By ~ 12

Author(s):

H Gardener ◽

K Munger ◽

T Chitnis ◽

D Spiegelman ◽

A Ascherio

Keyword(s):

Multiple Sclerosis ◽

Hand Preference ◽

The United States ◽

In Utero ◽

Health Study ◽

Unknown Etiology ◽

Left Handed ◽

Increased Risk ◽

Incident Cases ◽

The Relationship

Background Left-handedness has been studied as a marker for in-utero exposure to sex steroid hormones, and an increased risk of autoimmune and immune disorders among left-handed individuals has been suggested. Objective This study examines the relationship between hand preference and risk of multiple sclerosis, a presumed autoimmune disorder of unknown etiology. Methods The study population comprised participants in the Nurses’ Health Study, an ongoing prospective cohort study of 121,701 female nurses in the United States with followup from 1976 to 2002. The nurses were asked to report their natural hand preference (right, left, ambidextrous, forced to change). Results During followup 210 incident cases with multiple sclerosis were confirmed. A 62% increased risk of multiple sclerosis was observed among women who were naturally left handed as compared to those who were naturally right handed (95% CI: 1.04–2.53). Conclusions This study suggests a modest increase in risk of multiple sclerosis among left-handed women. Further investigation of this relationship is suggested in other populations including both males and females. While the current results suggest that prenatal exposure to sex hormones may play a role in multiple sclerosis risk, direct examination of the relationship between in-utero hormone exposure and hand preference is necessary before any conclusions can be drawn.

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Association between uric acid and metabolic syndrome in elderly women

Open Medicine ◽

10.1515/med-2018-0027 ◽

2018 ◽

Vol 13 (1) ◽

pp. 172-177 ◽

Cited By ~ 9

Author(s):

Hui-Juan Wang ◽

Lei-Zhi Shi ◽

Cun-Fei Liu ◽

Shi-Min Liu ◽

Song-Tao Shi

Keyword(s):

Metabolic Syndrome ◽

Uric Acid ◽

Elderly Women ◽

Serum Uric Acid Level ◽

Health Examination ◽

Logistic Regression Models ◽

Increased Risk ◽

Individual Variables ◽

The Relationship ◽

Fourth Quartile

AbstractObjectiveTo investigate the relationship between uric acid and metabolic syndrome (MetS) in elderly women.MethodsA total of 468 women aged ≥60 years participating in a health examination were enrolled. The association between uric acid and MetS and its individual variables was evaluated by univariate and multivariate logistic regression models.ResultsA dose-response relationship was observed for the prevalence of MetS and uric acid quartiles. Subjects in the second, third and fourth quartile of uric acid had a 2.23-fold, 2.25-fold and 4.41-fold increased risk, respectively, of MetS than those in the first uric acid quartile (p for trend <0.001). Furthermore, each 1 mg/dl increment of serum uric acid level had a 1.38-fold increased risk of MetS (OR 1.38; 95% CI, 1.14-1.69; p=0.001).ConclusionsOur present study demonstrated that elevated uric acid was positively associated with the prevalence of MetS in elderly women. Further random control trials are needed to elucidate the effectiveness of treatment of hyperuricaemia in reducing the incidence of MetS in elderly women.

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